Ileal pouch symptoms do not correlate with inflammation of the pouch

Clinical Gastroenterology and Hepatology

Volumn 12, Issue 5, 2014, Pages 831-837.e2

  Ben Bassat, Ofer ^a   Tyler, Andrea D ^a   Xu, Wei ^b   Kirsch, Richard ^a   Schaeffer, David F ^a   Walsh, Joanna ^a   Steinhart, A Hillary ^a,c   Greenberg, Gordon R ^a,c   Cohen, Zane ^a,c   Silverberg, Mark S ^a,c   McLeod, Robin S ^a,b,c  

^a MOUNT SINAI HOSPITAL   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

Ileal Pouch Anal Anastomosis; Inflammatory Bowel Disease; Pouchitis; Ulcerative Colitis

Indexed keywords

ADULT; AGED; ANUS FISTULA; ARTICLE; CORRELATIONAL STUDY; CROSS-SECTIONAL STUDY; ENDOSCOPIC MUCOSAL RESECTION; FEMALE; HUMAN; ILEITIS; ILEUM POUCH; INTESTINE ENDOSCOPY; MAJOR CLINICAL STUDY; MALE; POUCHITIS ACTIVITY SCORE; POUCHITIS DISEASE ACTIVITY INDEX; RECTUM HEMORRHAGE; SCORING SYSTEM; ADOLESCENT; BIOPSY; CANADA; COLOSTOMY BAG; CYTOCHEMISTRY; DECISION SUPPORT SYSTEM; ENDOSCOPY; EVALUATION STUDY; MIDDLE AGED; PATHOLOGY; POUCHITIS; PROCEDURES; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BIOPSY; CANADA; COLONIC POUCHES; CROSS-SECTIONAL STUDIES; DECISION SUPPORT TECHNIQUES; ENDOSCOPY; FEMALE; HISTOCYTOCHEMISTRY; HUMANS; MALE; MIDDLE AGED; POUCHITIS; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

EID: 84899048895     PISSN: 15423565     EISSN: 15427714     Source Type: Journal    
DOI: 10.1016/j.cgh.2013.09.027     Document Type: Article

References (18)

1. Shen B., Achkar J.-P., Lashner B.A., et al. Irritable pouch syndrome: a new category of diagnosis for symptomatic patients with ileal-pouch anal anastomosis. Am J Gastroenterol 2002, 97:972-977.
2. Sandborn W.J. Pouchitis following ileal pouch-anal anastomosis: definition, pathogenesis and treatment. Gastroenterology 1994, 107:1856-1860.
3. Sandborn W.J., Tremaine W.J., Batts K.P., et al. Pouchitis after ileal pouch-anal anastomosis: a pouchitis disease activity index. Mayo Clin Proc 1994, 69:409-415.
4. Moskowitz R.L., Sheperd N.A., Nicholls R.J. An assessment of inflammation in the reservoir after restorative proctocolectomy with ileoanal ileal reservoir. Int J Colorect Dis 1986, 1:167-174.
5. Shen B., Achkar J.-P., Lashner B.A., et al. Endoscopic and histologic evaluations together with symptom assessment are required to diagnose pouchitis. Gastroenterology 2001, 121:261-267.
6. Heuschen U.A., Autschbach F., Allemeyer E.H., et al. Long-term follow-up after ileoanal pouch procedure: algorithm for diagnosis, classification, and management of pouchitis. Dis Colon Rectum 2001, 44:487-499.
7. Heuschen U.A., Allemeyer E.H., Hinz U., et al. Diagnosing pouchitis: comparative validation of two scoring systems in routine follow-up. Dis Colon Rectum 2002, 45:776-788.
8. Tyler A.D., Milgrom R., Stempak J.M., et al. The NOD2insC polymorphism is associated with worse outcome following ileal pouch-anal anastomosis for ulcerative colitis. Gut 2013, 62:1433-1439.
9. Tyler A.D., Milgrom R., Xu W., et al. Antimicrobial antibodies are associated with a Crohn's disease-like phenotype after ileal pouch-anal anastomosis. Clin Gastroenterol Hepatol 2012, 10:507-512.
10. Colombel J.-F., Sandborn W.J., Reinisch W., et al. Infliximab, azathioprine or combination therapy for Crohn's disease. NEngl J Med 2010, 362:1383-1395.
11. Keighley M.R.B. Review article: the management of pouchitis. Aliment Pharmacol Ther 1996, 10:449-457.
12. Madden M.V., Farthing M.J.G., Nicholls R.J. Inflammation in ileal reservoirs: 'pouchitis'. Gut 1990, 31:247-249.
13. Zella G.C., Hait E.J., Glavan T., et al. Distinct microbiome in pouchitis compared to healthy pouches in ulcerative colitis and familial adenomatous polyposis. Inflamm Bowel Dis 2011, 17:1092-1100.
14. Tyler A.D., Berard N., Kabakchiev B., et al. Characterization of the gut-associated microbiome in inflammatory pouch complications following ileal pouch-anal anastomosis. PLoS One 2013, 8:e66934.
15. Shen B., Fazio V.W., Remzi F.H., et al. Comprehensive evaluation of inflammatory and noninflammatory sequelae of ileal pouch-anal anastomoses. Am J Gastroenterol 2005, 100:93-101.
16. Lofberg R., Liljeqvist L., Lindquist K., et al. Dysplasia and DNA aneuploidy in a pelvic pouch. Report of a case. Dis Colon Rectum 1991, 34:280-284.
17. Veress B., Reinholt F.P., Lindquist K., et al. Long-term histomorphological surveillance of the pelvic ileal pouch. Dysplasia develops in a subgroup of patients. Gastroenterology 1995, 109:1090-1097.
18. Shepherd N.A. Pouchitis and neoplasia in the pelvic ileal reservoir. Gastroenterology 1995, 109:1381-1396.