Inhibitory effect of a novel naphthoquinone derivative on proliferation of vascular smooth muscle cells through suppression of platelet-derived growth factor receptor β tyrosine kinase

European Journal of Pharmacology

Volumn 733, Issue 1, 2014, Pages 81-89

  Kim, Yohan ^a   Han, Joo Hui ^a   Yun, Eunju ^a   Jung, Sang Hyuk ^a   Lee, Jung Jin ^a   Song, Gyu Yong ^a   Myung, Chang Seon ^a  

^a Chungnam National University   (South Korea)

Author keywords

2 Undecylsulfonyl DMNQ; Cardiovascular disease; Platelet derived growth factor receptor ; Proliferation; Vascular smooth muscle cell

Indexed keywords

2 UNDECYLSULFONYL 5,8 DIMETHOXY 1,4 NAPHTHOQUINONE; ANTIMITOTIC AGENT; CYCLIN D1; CYCLIN E; DIGITONIN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; 2‐UNDECYLSULFONYL‐5,8‐DIMETHOXY‐1,4‐NAPHTHOQUINONE; DNA; NAPHTHOQUINONE; SULFONE;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; AUTOPHOSPHORYLATION; CELL COUNT; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DIMERIZATION; DNA SYNTHESIS; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; G1 PHASE CELL CYCLE CHECKPOINT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; S PHASE CELL CYCLE CHECKPOINT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE; ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; BIOSYNTHESIS; CELL CULTURE; CELL CYCLE CHECKPOINT; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; IMMUNOBLOTTING; PATHOLOGY; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; SIGNAL TRANSDUCTION;

ANIMALS; AORTA; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; DNA; IMMUNOBLOTTING; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NAPHTHOQUINONES; PHOSPHORYLATION; PROTEIN MULTIMERIZATION; RATS; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SIGNAL TRANSDUCTION; SULFONES;

EID: 84899041005     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.03.037     Document Type: Article

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