Emergence of daptomycin resistance in daptomycin-naïve rabbits with methicillin-resistant Staphylococcus aureus prosthetic joint infection is associated with resistance to host defense cationic peptides and mprF polymorphisms.

PloS one

Volumn 8, Issue 8, 2013, Pages

  Mishra, Nagendra N ^a   Yang, Soo Jin ^b   Chen, Liang ^b   Muller, Claudette ^b   Saleh Mghir, Azzam ^b   Kuhn, Sebastian ^b   Peschel, Andreas ^b   Yeaman, Michael R ^b   Nast, Cynthia C ^b   Kreiswirth, Barry N ^b   Crémieux, Anne Claude ^b   Bayer, Arnold S ^b  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINOACYLTRANSFERASE; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; BACTERIAL PROTEIN; DAPTOMYCIN; FATTY ACID; MPRF PROTEIN, STAPHYLOCOCCUS AUREUS; PHOSPHOLIPID;

ANIMAL; ANTIBIOTIC RESISTANCE; CELL WALL; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HOST PATHOGEN INTERACTION; JOINT PROSTHESIS; METABOLISM; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MICROBIOLOGY; PHENOTYPE; RABBIT; SINGLE NUCLEOTIDE POLYMORPHISM; STAPHYLOCOCCAL INFECTIONS;

AMINOACYLTRANSFERASES; ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL PROTEINS; CELL WALL; DAPTOMYCIN; DRUG RESISTANCE, BACTERIAL; FATTY ACIDS; GENE EXPRESSION REGULATION, BACTERIAL; GENOTYPE; HOST-PATHOGEN INTERACTIONS; JOINT PROSTHESIS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; PHENOTYPE; PHOSPHOLIPIDS; POLYMORPHISM, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; RABBITS; STAPHYLOCOCCAL INFECTIONS;

EID: 84899039263     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0071151     Document Type: Article

References (0)