Cyclooxygenase-1 mediated platelet reactivity in young male smokers

Clinical and Applied Thrombosis/Hemostasis

Volumn 20, Issue 4, 2014, Pages 371-377

  Loke, Wai Mun ^a   Sing, Karen Lam Mok ^a   Lee, Chung Yung J ^a   Chong, Wan Ling ^a   Chew, Soh Eng ^a   Huang, Huiwen ^a   Looi, Woan Foon ^a   Quek, Amy M L ^a   Lim, Erle C H ^a   Seet, Raymond Chee Seong ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

atherosclerosis; platelet dysfunction; platelet function; vascular disease

Indexed keywords

11 DEHYDROXYTHROMBOXANE B2; COLLAGEN; COTININE; CYCLOOXYGENASE 1; NICOTINE; THROMBOXANE; THROMBOXANE B2; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; PTGS1 PROTEIN, HUMAN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; FATTY ACID BLOOD LEVEL; HUMAN; MALE; PLATELET REACTIVITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPEAT PROCEDURE; SMOKING; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE VOLUME; URINE LEVEL; BLOOD; METABOLISM; THROMBOCYTE; URINE;

ADULT; BIOLOGICAL MARKERS; BLOOD PLATELETS; CYCLOOXYGENASE 1; HUMANS; MALE; PLATELET AGGREGATION; SMOKING; THROMBOXANE B2;

EID: 84899032500     PISSN: 10760296     EISSN: 19382723     Source Type: Journal    
DOI: 10.1177/1076029612466284     Document Type: Article

References (31)

1. Villablanca AC, McDonald JM, Rutledge JC. Smoking and cardiovascular disease. Clin Chest Med. 2000 ; 21 (1). 159-172
2. Rosamond W, Flegal K, Furie K, et al. Heart disease and stroke statistics - 2008 update: a report from the American Heart Association statistics committee and stroke statistics subcommittee. Circulation. 2008 ; 117 (4). e25 - e146
3. Edwards R. The problem of tobacco smoking. Br Med J. 2004 ; 328 (7433). 217-219
4. Ruggeri Z. Platelets in atherothrombosis. Nat Med. 2002 ; 8 (11). 1227-1234
5. Smith WL, Langenbach R. Why there are two cyclooxygenase isozymes. J Clin Invest. 2001 ; 107 (12). 1491-1495
6. Davis JW, Arnold J. Time course of some effects of cigarette smoking on platelets. J Intern Med. 1992 ; 231 (1). 31-36
7. Casey R, Joyce M, Roche-Nagle G, Cox D, Bouchier-Hayes D. Young male smokers have altered platelets and endothelium that precedes atherosclerosis. J Surg Res. 2004 ; 116 (2). 227-233
8. Fusegawa Y, Handa S. Platelet aggregation induced by ADP or epinephrine is enhanced in habitual smokers. Thromb Res. 2000 ; 97 (5). 287-295
9. Toivanen J, Ylikorkala O, Viinikka L. Effects of smoking and nicotine on human prostacyclin and thromboxane production in vivo and in vitro. Toxicol Appl Pharmacol. 1986 ; 82 (2). 301-306
10. Dotevall A, Rångemark C, Eriksson E, Kutti J, Wadenvik H, Wennmalm A. Cigarette smoking increases thromboxane A2 formation without affecting platelet survival in young healthy females. Thromb Haemost. 1992 ; 68 (5). 583-588
11. Patrignani P, Sciulli M, Manarini S, Santini G, Cerletti C, Evangelista V. COX-2 is not involved in thromboxane biosynthesis by activated human platelets. J Physiol Pharmacol. 1999 ; 50 (4). 661-667
12. National Health Survey 2010. Singapore: Ministry of Health ;
13. Toth O, Calatzis A, Penz S, Losonczy H, Siess W. Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. Thromb Haemost. 2006 ; 96 (6). 781-788
14. Uedelhoven W, Meese C, Weber P. Analysis of the major urinary thromboxane metabolites, 2, 3-dinorthromboxane B2 and 11-dehydrothromboxane B2, by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry. J. Chromatogr. 1989 ; 497: 1-16
15. Shin H-S, Kim J-G, Shin YJ, Jee SH. Sensitive and simple method for the determination of nicotine and cotinine in human urine, plasma and saliva by gas chromatography-mass spectrometry. J. Chromatogr. B. 2002 ; 769 (1). 177-183
16. Man CN, Gam LH, Ismail S, Lajis R, Awang R. Simple, rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 ; 844 (2). 322-327
17. Goh L, Chua T, Kang V, et al. Ministry of health clinical practice guidelines: screening of cardiovascular disease and risk factors. Singapore Med J. 2011 ; 52 (3). 220-225
18. Taylor RR, Sturm M, Vandongen R, Strophair J, Beilin LJ. Whole blood platelet aggregation is not affected by cigarette smoking but is sex-related. Clin Exp Pharmacol Physiol. 1987 ; 14 (8). 665-671
19. Michelson AD. Methods for the measurement of platelet function. Am J Cardiol. 2009 ; 103 (3 suppl). 20A - 26A
20. Schweer H, Meese CO, Fürst O, Kühl PG, Seyberth HW. Tandem mass spectrometric determination of 11-dehydrothromboxane B2, an index metabolite of thromboxane B2 in plasma and urine. Anal Biochem. 1987 ; 164 (1). 156-163
21. Wennmalm Å, Benthin G, GranstrÖm EF, Persson L, Winell S. Maintained hyperexcretion of thromboxane A2 metabolite in healthy young cigarette smokers: results from a prospective study in randomly sampled males with stable smoking habits. Clin Physiol. 1993 ; 13 (3). 257-264
22. Rangemark C, Benthin G, Granstrom E, Persson L, Winell S, Wennmalm A. Tobacco use and urinary excretion of thromboxane A2 and prostacyclin metabolites in women stratified by age. Circulation. 1992 ; 86 (5). 1495-1500
23. Rioux N, Castonguay A. The induction of cyclooxygenase-1 by a tobacco carcinogen in U937 human macrophages is correlated to the activation of NF- B. Carcinogenesis. 2000 ; 21 (9). 1745-1751
24. Weyrich AS, Schwertz H, Kraiss LW, Zimmerman GA. Protein synthesis by platelets: historical and new perspectives. J Thromb Haemost. 2009 ; 7 (2). 241-246
25. Baigent C, Blackwell L, Collins R, et al. Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials. Lancet. 2009 ; 373 (9678). 1849-1860
26. Kario K, Matsuo T, Nakao K. Cigarette smoking increases the mean platelet volume in elderly patients with risk factors for atherosclerosis. Clin Lab Haematol. 1992 ; 14 (4). 281-287
27. Coban E, Bostan F, Ozdogan M. The mean platelet volume in subjects with impaired fasting glucose. Platelets. 2006 ; 17 (1). 67-69
28. Nadar SK, Blann AD, Kamath S, Beevers DG, Lip GYH. Platelet indexes in relation to target organ damage in high-risk hypertensive patients: a substudy of the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT). J Am Coll Cardiol. 2004 ; 44 (2). 415-422
29. Tavil Y, Sen N, Yazici HU, Hizal F, Abac A, Cengel A. Mean platelet volume in patients with metabolic syndrome and its relationship with coronary artery disease. Thromb Res. 2007 ; 120 (2). 245-250
30. Coban E, Ozdogan M, Yazicioglu G, Akcit F. The mean platelet volume in patients with obesity. Int J Clin Pract. 2005 ; 59 (8). 981-982
31. Gawaz M, Korbinian B, Timm D, et al. Platelets induce alterations of chemotactic and adhesive properties of endothelial cells mediated through an interleukin-1-dependent mechanism. Implications for atherogenesis. Atherosclerosis. 2000 ; 148 (1). 75-85