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Volumn 19, Issue 3, 2014, Pages 283-289
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Evacetrapib at a supratherapeutic steady state concentration does not prolong QT in a thorough QT/QTc study in healthy participants
a
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Author keywords
cholesteryl ester transfer protein; evacetrapib; QT interval
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Indexed keywords
ALANINE AMINOTRANSFERASE;
ASPARTATE AMINOTRANSFERASE;
BILIRUBIN;
ENOXAPARIN;
EVACETRAPIB;
MOXIFLOXACIN;
PLACEBO;
WARFARIN;
ANTIINFECTIVE AGENT;
BENZODIAZEPINE DERIVATIVE;
CHOLESTEROL ESTER TRANSFER PROTEIN;
QUINOLONE DERIVATIVE;
ABDOMINAL PAIN;
ADULT;
AGED;
AREA UNDER THE CURVE;
ARTICLE;
BODY MASS;
CONCENTRATION RESPONSE;
CONSTIPATION;
CONTROLLED STUDY;
CROSSOVER PROCEDURE;
DECREASED APPETITE;
DEEP VEIN THROMBOSIS;
DIARRHEA;
DRUG BLOOD LEVEL;
DRUG ELIMINATION;
DRUG ERUPTION;
DRUG HALF LIFE;
DRUG SAFETY;
DRUG TOLERABILITY;
ELECTROCARDIOGRAPHY;
ELECTROCARDIOGRAPHY MONITORING;
FEMALE;
FLATULENCE;
HEADACHE;
HOT FLUSH;
HUMAN;
HUMAN EXPERIMENT;
HYPERTRANSAMINASEMIA;
INSOMNIA;
MALE;
MAXIMUM PLASMA CONCENTRATION;
NAUSEA;
NORMAL HUMAN;
PARESTHESIA;
PHASE 1 CLINICAL TRIAL;
PLASMA CONCENTRATION-TIME CURVE;
PRIORITY JOURNAL;
PRURITUS;
QRS COMPLEX;
QT INTERVAL;
QT PROLONGATION;
RANDOMIZED CONTROLLED TRIAL;
STEADY STATE;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ANTAGONISTS AND INHIBITORS;
CHEMICALLY INDUCED;
DOSE RESPONSE;
HALF LIFE TIME;
HEART VENTRICLE TACHYCARDIA;
ADULT;
AGED;
ANTI-BACTERIAL AGENTS;
AREA UNDER CURVE;
BENZODIAZEPINES;
BODY MASS INDEX;
CHOLESTEROL ESTER TRANSFER PROTEINS;
CROSS-OVER STUDIES;
DOSE-RESPONSE RELATIONSHIP, DRUG;
ELECTROCARDIOGRAPHY;
FEMALE;
FLUOROQUINOLONES;
HALF-LIFE;
HUMANS;
MALE;
TACHYCARDIA, VENTRICULAR;
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EID: 84898937203
PISSN: 10742484
EISSN: 19404034
Source Type: Journal
DOI: 10.1177/1074248413510784 Document Type: Article |
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Times cited : (10)
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References (11)
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