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Volumn 20, Issue 3, 2014, Pages 369-375

Tranexamic acid as adjunct therapy to bypassing agents in haemophilia A patients with inhibitors

Author keywords

Activated prothrombin complex concentrates; Haemophilia; Inhibitors; Recombinant activated FVII; Tranexamic acid

Indexed keywords

ACTIVATED PROTHROMBIN COMPLEX; BLOOD CLOTTING FACTOR; D DIMER; FIBRINOGEN; RECOMBINANT ACTIVATED FACTOR VII; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TRANEXAMIC ACID; UNCLASSIFIED DRUG; ANTIFIBRINOLYTIC AGENT; BLOOD CLOTTING INHIBITOR; PROTHROMBIN COMPLEX CONCENTRATES;

EID: 84898914313     PISSN: 13518216     EISSN: 13652516     Source Type: Journal    
DOI: 10.1111/hae.12318     Document Type: Article
Times cited : (32)

References (38)
  • 1
    • 84862848720 scopus 로고    scopus 로고
    • How I treat inhibitors in haemophilia
    • Makris M, Hay CR, Gringeri A, D'Oiron R. How I treat inhibitors in haemophilia. Haemophilia 2012; 18(Suppl. 4): 48-53.
    • (2012) Haemophilia , vol.18 , Issue.SUPPL. 4 , pp. 48-53
    • Makris, M.1    Hay, C.R.2    Gringeri, A.3    D'Oiron, R.4
  • 2
    • 84857984508 scopus 로고    scopus 로고
    • Elective orthopaedic surgery for haemophilia patients with inhibitors: single centre experience of 40 procedures and review of the literature
    • Caviglia H, Candela M, Galatro G, Neme D, Moretti N, Bianco RP. Elective orthopaedic surgery for haemophilia patients with inhibitors: single centre experience of 40 procedures and review of the literature. Haemophilia 2011; 17: 910-9.
    • (2011) Haemophilia , vol.17 , pp. 910-919
    • Caviglia, H.1    Candela, M.2    Galatro, G.3    Neme, D.4    Moretti, N.5    Bianco, R.P.6
  • 3
    • 84876814220 scopus 로고    scopus 로고
    • SURgical interventions with FEIBA (SURF): international registry of surgery in haemophilia patients with inhibitory antibodies
    • Negrier C, Lienhart A, Numerof R et al. SURgical interventions with FEIBA (SURF): international registry of surgery in haemophilia patients with inhibitory antibodies. Haemophilia 2013; 19: e143-50.
    • (2013) Haemophilia , vol.19
    • Negrier, C.1    Lienhart, A.2    Numerof, R.3
  • 4
    • 79951875993 scopus 로고    scopus 로고
    • Experience of four UK comprehensive care centres using FEIBA(R) for surgeries in patients with inhibitors
    • Rangarajan S, Yee TT, Wilde J. Experience of four UK comprehensive care centres using FEIBA(R) for surgeries in patients with inhibitors. Haemophilia 2011; 17: 28-34.
    • (2011) Haemophilia , vol.17 , pp. 28-34
    • Rangarajan, S.1    Yee, T.T.2    Wilde, J.3
  • 6
    • 84860324856 scopus 로고    scopus 로고
    • Efficacy of FEIBA for acute bleeding and surgical haemostasis in haemophilia A patients with inhibitors: a multicentre registry in Turkey 41
    • Zulfikar B, Aydogan G, Salcioglu Z et al. Efficacy of FEIBA for acute bleeding and surgical haemostasis in haemophilia A patients with inhibitors: a multicentre registry in Turkey 41. Haemophilia 2012; 18: 383-91.
    • (2012) Haemophilia , vol.18 , pp. 383-391
    • Zulfikar, B.1    Aydogan, G.2    Salcioglu, Z.3
  • 8
    • 63049090494 scopus 로고    scopus 로고
    • Differential response to bypassing agents complicates treatment in patients with haemophilia and inhibitors
    • Berntorp E. Differential response to bypassing agents complicates treatment in patients with haemophilia and inhibitors. Haemophilia 2009; 15: 3-10.
    • (2009) Haemophilia , vol.15 , pp. 3-10
    • Berntorp, E.1
  • 9
    • 84857108099 scopus 로고    scopus 로고
    • On-demand treatment of bleeds in haemophilia patients with inhibitors: strategies for securing and maintaining predictable efficacy with recombinant activated factor VII 13
    • Sorensen B, Dargaud Y, Kenet G et al. On-demand treatment of bleeds in haemophilia patients with inhibitors: strategies for securing and maintaining predictable efficacy with recombinant activated factor VII 13. Haemophilia 2012; 18: 255-62.
    • (2012) Haemophilia , vol.18 , pp. 255-262
    • Sorensen, B.1    Dargaud, Y.2    Kenet, G.3
  • 10
    • 84876814770 scopus 로고    scopus 로고
    • Case studies in the management of refractory bleeding in patients with haemophilia A and inhibitors
    • Valentino LAFAU, Allen GF, Gill JCFAU et al. Case studies in the management of refractory bleeding in patients with haemophilia A and inhibitors. Haemophilia 2013; 19: 151-66.
    • (2013) Haemophilia , vol.19 , pp. 151-166
    • Valentino, L.A.F.A.U.1    Allen, G.F.2    Gill, J.C.F.A.U.3
  • 12
    • 84860319276 scopus 로고    scopus 로고
    • Thrombin activatable fibrinolysis inhibitor activation and bleeding in haemophilia A
    • Foley JH, Nesheim ME, Rivard GE, Brummel-Ziedins KE. Thrombin activatable fibrinolysis inhibitor activation and bleeding in haemophilia A. Haemophilia 2012; 18: e316-22.
    • (2012) Haemophilia , vol.18
    • Foley, J.H.1    Nesheim, M.E.2    Rivard, G.E.3    Brummel-Ziedins, K.E.4
  • 13
    • 75649122555 scopus 로고    scopus 로고
    • The effect of tranexamic acid on reducing blood loss in cementless total hip arthroplasty under epidural anesthesia
    • Kazemi SM, Mosaffa F, Eajazi A et al. The effect of tranexamic acid on reducing blood loss in cementless total hip arthroplasty under epidural anesthesia. Orthopedics 2010; 33: 17.
    • (2010) Orthopedics , vol.33 , pp. 17
    • Kazemi, S.M.1    Mosaffa, F.2    Eajazi, A.3
  • 14
    • 84861101002 scopus 로고    scopus 로고
    • Should antifibrinolytics be given in all patients with trauma?
    • Levi M. Should antifibrinolytics be given in all patients with trauma? Curr Opin Anaesthesiol 2012; 25: 385-8.
    • (2012) Curr Opin Anaesthesiol , vol.25 , pp. 385-388
    • Levi, M.1
  • 15
    • 84875398229 scopus 로고    scopus 로고
    • The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients
    • Roberts I, Shakur H, Coats T et al. The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Health Technol Assess 2013; 17: 1-79.
    • (2013) Health Technol Assess , vol.17 , pp. 1-79
    • Roberts, I.1    Shakur, H.2    Coats, T.3
  • 16
    • 84863222250 scopus 로고    scopus 로고
    • Combined treatment with APCC (FEIBA(R)) and tranexamic acid in patients with haemophilia A with inhibitors and in patients with acquired haemophilia A-a two-centre experience
    • Holmstrom M, Tran HT, Holme PA. Combined treatment with APCC (FEIBA(R)) and tranexamic acid in patients with haemophilia A with inhibitors and in patients with acquired haemophilia A-a two-centre experience. Haemophilia 2012; 18: 544-9.
    • (2012) Haemophilia , vol.18 , pp. 544-549
    • Holmstrom, M.1    Tran, H.T.2    Holme, P.A.3
  • 17
    • 84877607719 scopus 로고    scopus 로고
    • Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives
    • Young G, Sorensen B, Dargaud Y, Negrier C, Brummel-Ziedins K, Key NS. Thrombin generation and whole blood viscoelastic assays in the management of hemophilia: current state of art and future perspectives. Blood 2013; 121: 1944-50.
    • (2013) Blood , vol.121 , pp. 1944-1950
    • Young, G.1    Sorensen, B.2    Dargaud, Y.3    Negrier, C.4    Brummel-Ziedins, K.5    Key, N.S.6
  • 18
    • 61849136778 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology
    • Levi M, Toh CH, Thachil J, Watson HG. Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. Br J Haematol 2009; 145: 24-33.
    • (2009) Br J Haematol , vol.145 , pp. 24-33
    • Levi, M.1    Toh, C.H.2    Thachil, J.3    Watson, H.G.4
  • 19
    • 0020662181 scopus 로고
    • The use of factor eight inhibitor by-passing activity (FEIBA immuno) product for treatment of bleeding episodes in hemophiliacs with inhibitors
    • Hilgartner MW, Knatterud GL. The use of factor eight inhibitor by-passing activity (FEIBA immuno) product for treatment of bleeding episodes in hemophiliacs with inhibitors. Blood 1983; 61: 36-40.
    • (1983) Blood , vol.61 , pp. 36-40
    • Hilgartner, M.W.1    Knatterud, G.L.2
  • 20
    • 0019426632 scopus 로고
    • The effect of activated prothrombin-complex concentrate (FEIBA) on joint and muscle bleeding in patients with hemophilia A and antibodies to factor VIII. A double-blind clinical trial
    • Sjamsoedin LJ, Heijnen L, Mauser-Bunschoten EP et al. The effect of activated prothrombin-complex concentrate (FEIBA) on joint and muscle bleeding in patients with hemophilia A and antibodies to factor VIII. A double-blind clinical trial. N Engl J Med 1981; 305: 717-21.
    • (1981) N Engl J Med , vol.305 , pp. 717-721
    • Sjamsoedin, L.J.1    Heijnen, L.2    Mauser-Bunschoten, E.P.3
  • 21
    • 40349085780 scopus 로고    scopus 로고
    • Single 270 microg kg(-1)-dose rFVIIa vs. standard 90 microg kg(-1)-dose rFVIIa and APCC for home treatment of joint bleeds in haemophilia patients with inhibitors: a randomized comparison
    • Young G, Shafer FE, Rojas P, Seremetis S. Single 270 microg kg(-1)-dose rFVIIa vs. standard 90 microg kg(-1)-dose rFVIIa and APCC for home treatment of joint bleeds in haemophilia patients with inhibitors: a randomized comparison. Haemophilia 2008; 14: 287-94.
    • (2008) Haemophilia , vol.14 , pp. 287-294
    • Young, G.1    Shafer, F.E.2    Rojas, P.3    Seremetis, S.4
  • 22
    • 33846185403 scopus 로고    scopus 로고
    • A randomized comparison of bypassing agents in hemophilia complicated by an inhibitor: the FEIBA NovoSeven Comparative (FENOC) Study
    • Astermark J, Donfield SM, Dimichele DM et al. A randomized comparison of bypassing agents in hemophilia complicated by an inhibitor: the FEIBA NovoSeven Comparative (FENOC) Study. Blood 2007; 109: 546-51.
    • (2007) Blood , vol.109 , pp. 546-551
    • Astermark, J.1    Donfield, S.M.2    Dimichele, D.M.3
  • 23
    • 78049307974 scopus 로고    scopus 로고
    • Postauthorization safety surveillance of ADVATE [antihaemophilic factor (recombinant), plasma/albumin-free method] demonstrates efficacy, safety and low-risk for immunogenicity in routine clinical practice
    • Oldenburg J, Goudemand J, Valentino L et al. Postauthorization safety surveillance of ADVATE [antihaemophilic factor (recombinant), plasma/albumin-free method] demonstrates efficacy, safety and low-risk for immunogenicity in routine clinical practice. Haemophilia 2010; 16: 866-77.
    • (2010) Haemophilia , vol.16 , pp. 866-877
    • Oldenburg, J.1    Goudemand, J.2    Valentino, L.3
  • 24
    • 4043155658 scopus 로고    scopus 로고
    • Sequential therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors
    • Schneiderman J, Nugent DJ, Young G. Sequential therapy with activated prothrombin complex concentrate and recombinant factor VIIa in patients with severe haemophilia and inhibitors. Haemophilia 2004; 10: 347-51.
    • (2004) Haemophilia , vol.10 , pp. 347-351
    • Schneiderman, J.1    Nugent, D.J.2    Young, G.3
  • 25
    • 34248551364 scopus 로고    scopus 로고
    • Sequential therapy with activated prothrombin complex concentrates and recombinant FVIIa in patients with severe haemophilia and inhibitors: update of our previous experience
    • Schneiderman J, Rubin E, Nugent DJ, Young G. Sequential therapy with activated prothrombin complex concentrates and recombinant FVIIa in patients with severe haemophilia and inhibitors: update of our previous experience. Haemophilia 2007; 13: 244-8.
    • (2007) Haemophilia , vol.13 , pp. 244-248
    • Schneiderman, J.1    Rubin, E.2    Nugent, D.J.3    Young, G.4
  • 26
    • 67649868161 scopus 로고    scopus 로고
    • Concomitant infusion of low doses of rFVIIa and FEIBA in haemophilia patients with inhibitors
    • Martinowitz U, Livnat T, Zivelin A, Kenet G. Concomitant infusion of low doses of rFVIIa and FEIBA in haemophilia patients with inhibitors. Haemophilia 2009; 15: 904-10.
    • (2009) Haemophilia , vol.15 , pp. 904-910
    • Martinowitz, U.1    Livnat, T.2    Zivelin, A.3    Kenet, G.4
  • 27
    • 80053570793 scopus 로고    scopus 로고
    • Parallel use of by-passing agents in haemophilia with inhibitors: a critical review
    • Ingerslev J, Sorensen B. Parallel use of by-passing agents in haemophilia with inhibitors: a critical review. Br J Haematol 2011; 155: 256-62.
    • (2011) Br J Haematol , vol.155 , pp. 256-262
    • Ingerslev, J.1    Sorensen, B.2
  • 28
    • 77953521329 scopus 로고    scopus 로고
    • Plasma and cellular contributions to fibrin network formation, structure and stability
    • Wolberg AS. Plasma and cellular contributions to fibrin network formation, structure and stability. Haemophilia 2010; 16(Suppl. 3): 7-12.
    • (2010) Haemophilia , vol.16 , Issue.SUPPL. 3 , pp. 7-12
    • Wolberg, A.S.1
  • 29
    • 79952065857 scopus 로고    scopus 로고
    • Factor XIII combined with recombinant factor VIIa: a new means of treating severe hemophilia A
    • Rea CJ, Foley JH, Ingerslev J, Sorensen B. Factor XIII combined with recombinant factor VIIa: a new means of treating severe hemophilia A. J Thromb Haemost 2011; 9: 510-6.
    • (2011) J Thromb Haemost , vol.9 , pp. 510-516
    • Rea, C.J.1    Foley, J.H.2    Ingerslev, J.3    Sorensen, B.4
  • 30
    • 84859815893 scopus 로고    scopus 로고
    • Solulin increases clot stability in whole blood from humans and dogs with hemophilia
    • Foley JH, Petersen KU, Rea CJ et al. Solulin increases clot stability in whole blood from humans and dogs with hemophilia. Blood 2012; 119: 3622-8.
    • (2012) Blood , vol.119 , pp. 3622-3628
    • Foley, J.H.1    Petersen, K.U.2    Rea, C.J.3
  • 31
    • 84856142615 scopus 로고    scopus 로고
    • Factor XIII in the treatment of hemophilia A
    • Rea CJ, Foley JH, Sorensen B. Factor XIII in the treatment of hemophilia A. N Engl J Med 2012; 366: 281-3.
    • (2012) N Engl J Med , vol.366 , pp. 281-283
    • Rea, C.J.1    Foley, J.H.2    Sorensen, B.3
  • 32
    • 36348983304 scopus 로고    scopus 로고
    • Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A
    • Hvas AM, Sorensen HT, Norengaard L, Christiansen K, Ingerslev J, Sorensen B. Tranexamic acid combined with recombinant factor VIII increases clot resistance to accelerated fibrinolysis in severe hemophilia A. J Thromb Haemost 2007; 5: 2408-14.
    • (2007) J Thromb Haemost , vol.5 , pp. 2408-2414
    • Hvas, A.M.1    Sorensen, H.T.2    Norengaard, L.3    Christiansen, K.4    Ingerslev, J.5    Sorensen, B.6
  • 34
    • 77954717667 scopus 로고    scopus 로고
    • Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial
    • Shakur H, Roberts I, Bautista R et al. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 2010; 376: 23-32.
    • (2010) Lancet , vol.376 , pp. 23-32
    • Shakur, H.1    Roberts, I.2    Bautista, R.3
  • 35
    • 11044236959 scopus 로고    scopus 로고
    • Minimizing factor requirements for surgery without increased risk
    • Schulman S, Loogna J, Wallensten R. Minimizing factor requirements for surgery without increased risk. Haemophilia 2004; 10(Suppl. 4): 35-40.
    • (2004) Haemophilia , vol.10 , Issue.SUPPL. 4 , pp. 35-40
    • Schulman, S.1    Loogna, J.2    Wallensten, R.3
  • 36
    • 84885297706 scopus 로고    scopus 로고
    • Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: a randomized controlled trial
    • 9
    • Wang Q, Liu J, Fan R et al. Tranexamic acid reduces postoperative blood loss of degenerative lumbar instability with stenosis in posterior approach lumbar surgery: a randomized controlled trial. Eur Spine J 2013; 22: 9: 2035-8.
    • (2013) Eur Spine J , vol.22 , pp. 2035-2038
    • Wang, Q.1    Liu, J.2    Fan, R.3
  • 37
    • 77949324354 scopus 로고    scopus 로고
    • Platelet binding and activity of recombinant factor VIIa
    • Hoffman M, Monroe DM. Platelet binding and activity of recombinant factor VIIa. Thromb Res 2010; 125(Suppl. 1): S16-8.
    • (2010) Thromb Res , vol.125 , Issue.SUPPL. 1
    • Hoffman, M.1    Monroe, D.M.2
  • 38
    • 84864445333 scopus 로고    scopus 로고
    • Unifying the mechanism of recombinant FVIIa action: dose dependence is regulated differently by tissue factor and phospholipids
    • Shibeko AM, Woodle SA, Lee TK, Ovanesov MV. Unifying the mechanism of recombinant FVIIa action: dose dependence is regulated differently by tissue factor and phospholipids. Blood 2012; 120: 891-9.
    • (2012) Blood , vol.120 , pp. 891-899
    • Shibeko, A.M.1    Woodle, S.A.2    Lee, T.K.3    Ovanesov, M.V.4


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