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Volumn 46, Issue 5, 2014, Pages 452-459

Polychemotherapy or gemcitabine in advanced pancreatic cancer: A meta-analysis

Author keywords

First line; Gemcitabine; Meta analysis; Overall survival; Pancreatic cancer; Polychemotherapy

Indexed keywords

CISPLATIN; FLUOROURACIL; GEMCITABINE; ANTINEOPLASTIC AGENT; BRIDGED COMPOUND; DEOXYCYTIDINE; PLATINUM DERIVATIVE; TAXANE; TAXOID;

EID: 84898913530     PISSN: 15908658     EISSN: 18783562     Source Type: Journal    
DOI: 10.1016/j.dld.2014.01.001     Document Type: Article
Times cited : (17)

References (46)
  • 1
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial
    • Burris H.A., Moore M.J., Andersen J., et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. Journal of Clinical Oncology 1997, 15:2403-2413.
    • (1997) Journal of Clinical Oncology , vol.15 , pp. 2403-2413
    • Burris, H.A.1    Moore, M.J.2    Andersen, J.3
  • 2
    • 34247188535 scopus 로고    scopus 로고
    • Meta-analyses of chemotherapy for locally advanced and metastatic pancreatic cancer
    • Sultana A., Smith C.T., Cunningham D., et al. Meta-analyses of chemotherapy for locally advanced and metastatic pancreatic cancer. Journal of Clinical Oncology 2007, 25:2607-2615.
    • (2007) Journal of Clinical Oncology , vol.25 , pp. 2607-2615
    • Sultana, A.1    Smith, C.T.2    Cunningham, D.3
  • 3
    • 42349093032 scopus 로고    scopus 로고
    • Metaanalysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer
    • Heinemann V., Boeck S., Hinke A., et al. Metaanalysis of randomized trials: evaluation of benefit from gemcitabine-based combination chemotherapy applied in advanced pancreatic cancer. BMC Cancer 2008, 8:82.
    • (2008) BMC Cancer , vol.8 , pp. 82
    • Heinemann, V.1    Boeck, S.2    Hinke, A.3
  • 4
    • 34249933404 scopus 로고    scopus 로고
    • Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
    • Moore M.J., Goldstein D., Hamm J., et al. Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group. Journal of Clinical Oncology 2007, 25:1960.
    • (2007) Journal of Clinical Oncology , vol.25 , pp. 1960
    • Moore, M.J.1    Goldstein, D.2    Hamm, J.3
  • 5
    • 65549150854 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
    • Van Cutsem E., Vervenne W.L., Bennouna J., et al. Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer. Journal of Clinical Oncology 2009, 27:2231.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 2231
    • Van Cutsem, E.1    Vervenne, W.L.2    Bennouna, J.3
  • 6
    • 77955914277 scopus 로고    scopus 로고
    • Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205
    • Philip P.A., Benedetti J., Corless C.L., et al. Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205. Journal of Clinical Oncology 2010, 28:3605.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 3605
    • Philip, P.A.1    Benedetti, J.2    Corless, C.L.3
  • 7
    • 37549027274 scopus 로고    scopus 로고
    • Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial
    • Cascinu S., Berardi R., Labianca R., et al. Cetuximab plus gemcitabine and cisplatin compared with gemcitabine and cisplatin alone in patients with advanced pancreatic cancer: a randomised, multicentre, phase II trial. Lancet Oncology 2008, 9:39.
    • (2008) Lancet Oncology , vol.9 , pp. 39
    • Cascinu, S.1    Berardi, R.2    Labianca, R.3
  • 8
    • 79955921754 scopus 로고    scopus 로고
    • FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer
    • Conroy T., Desseigne F., Ychou M., et al. FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer. New England Journal of Medicine 2011, 364:1817.
    • (2011) New England Journal of Medicine , vol.364 , pp. 1817
    • Conroy, T.1    Desseigne, F.2    Ychou, M.3
  • 9
    • 84886741654 scopus 로고    scopus 로고
    • Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine
    • Von Hoff D.D., Ervin T.J., Arena F.P., et al. Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine. New England Journal of Medicine 2013, 369:1691-1703.
    • (2013) New England Journal of Medicine , vol.369 , pp. 1691-1703
    • Von Hoff, D.D.1    Ervin, T.J.2    Arena, F.P.3
  • 10
    • 84872677684 scopus 로고    scopus 로고
    • Role of gemcitabine-based combination therapy in the management of advanced pancreatic cancer: a meta-analysis of randomised trials
    • Ciliberto D., Botta C., Correale P., et al. Role of gemcitabine-based combination therapy in the management of advanced pancreatic cancer: a meta-analysis of randomised trials. European Journal of Cancer 2013, 49:593-603.
    • (2013) European Journal of Cancer , vol.49 , pp. 593-603
    • Ciliberto, D.1    Botta, C.2    Correale, P.3
  • 11
    • 0032583387 scopus 로고    scopus 로고
    • Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints
    • Parmar M.K., Torri V., Stewart L. Extracting summary statistics to perform meta-analyses of the published literature for survival endpoints. Statistics in Medicine 1998, 17:2815-2834.
    • (1998) Statistics in Medicine , vol.17 , pp. 2815-2834
    • Parmar, M.K.1    Torri, V.2    Stewart, L.3
  • 12
    • 34547450763 scopus 로고    scopus 로고
    • Practical methods for incorporating summary time-to-event data into meta-analysis
    • Tierney J.F., Stewart L.A., Ghersi D., et al. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials 2007, 8:16.
    • (2007) Trials , vol.8 , pp. 16
    • Tierney, J.F.1    Stewart, L.A.2    Ghersi, D.3
  • 13
  • 14
    • 28344452125 scopus 로고    scopus 로고
    • A randomised, prospective, multicenter, phase III trial of gemcitabine, 5-fluorouracil (5-FU), folinic acid vs. gemcitabine alone in patients with advanced pancreatic cancer
    • LBA4009
    • Riess H., Helm A., Niedergethmann M., et al. A randomised, prospective, multicenter, phase III trial of gemcitabine, 5-fluorouracil (5-FU), folinic acid vs. gemcitabine alone in patients with advanced pancreatic cancer. Journal of Clinical Oncology 2005, 23:LBA4009.
    • (2005) Journal of Clinical Oncology , vol.23
    • Riess, H.1    Helm, A.2    Niedergethmann, M.3
  • 15
    • 84898861724 scopus 로고    scopus 로고
    • Randomized controlled trial of gemcitabine in combination with UFT versus gemcitabine alone in patients with advanced pancreatic cancer
    • Ohkawa S: (abstr. 4131)
    • Ohkawa S: Randomized controlled trial of gemcitabine in combination with UFT versus gemcitabine alone in patients with advanced pancreatic cancer. Journal of Clinical Oncology 2004, 22(Suppl. 14S). (abstr. 4131).
    • (2004) Journal of Clinical Oncology , vol.22 , Issue.SUPPL. 14S
  • 16
    • 23944500432 scopus 로고    scopus 로고
    • A prospective randomized trial of gemcitabine alone or gemcitabine+cisplatin in the treatment of metastatic pancreatic cancer
    • Li C.P., Chao Y. A prospective randomized trial of gemcitabine alone or gemcitabine+cisplatin in the treatment of metastatic pancreatic cancer. Journal of Clinical Oncology 2004, 22:4144.
    • (2004) Journal of Clinical Oncology , vol.22 , pp. 4144
    • Li, C.P.1    Chao, Y.2
  • 17
    • 33644881606 scopus 로고    scopus 로고
    • Gemcitabine in combination with cisplatin (GP) versus gemcitabine (G) alone in the treatment of locally advanced or metastatic pancreatic cancer: final results of a multicenter randomized phase II study
    • Viret F., Ychou M., Lepille D., et al. Gemcitabine in combination with cisplatin (GP) versus gemcitabine (G) alone in the treatment of locally advanced or metastatic pancreatic cancer: final results of a multicenter randomized phase II study. Journal of Clinical Oncology 2004, 22:4118.
    • (2004) Journal of Clinical Oncology , vol.22 , pp. 4118
    • Viret, F.1    Ychou, M.2    Lepille, D.3
  • 18
    • 0036637150 scopus 로고    scopus 로고
    • Gemcitabine or gemcitabine plus cisplatin for in 42 patients with locally advanced or metastatic pancreatic cancer
    • Wang X., Ni Q., Jin M., et al. Gemcitabine or gemcitabine plus cisplatin for in 42 patients with locally advanced or metastatic pancreatic cancer. Zhonghua zhong liu za zhi 2002, 24:404-407.
    • (2002) Zhonghua zhong liu za zhi , vol.24 , pp. 404-407
    • Wang, X.1    Ni, Q.2    Jin, M.3
  • 19
    • 0036682041 scopus 로고    scopus 로고
    • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
    • Berlin J.D., Catalano P., Thomas J.P., et al. Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. Journal of Clinical Oncology 2002, 20:3270-3275.
    • (2002) Journal of Clinical Oncology , vol.20 , pp. 3270-3275
    • Berlin, J.D.1    Catalano, P.2    Thomas, J.P.3
  • 20
    • 0037083621 scopus 로고    scopus 로고
    • Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: a prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale
    • Colucci G., Giuliani F., Gebbia V., et al. Gemcitabine alone or with cisplatin for the treatment of patients with locally advanced and/or metastatic pancreatic carcinoma: a prospective, randomized phase III study of the Gruppo Oncologia dell'Italia Meridionale. Cancer 2002, 94:902-910.
    • (2002) Cancer , vol.94 , pp. 902-910
    • Colucci, G.1    Giuliani, F.2    Gebbia, V.3
  • 21
    • 12244296736 scopus 로고    scopus 로고
    • Biweekly high-dose gemcitabine alone or in combination with capecitabine in patients with metastatic pancreatic adenocarcinoma: a randomized phase II trial
    • Scheithauer W., Schull B., Ulrich-Pur H., et al. Biweekly high-dose gemcitabine alone or in combination with capecitabine in patients with metastatic pancreatic adenocarcinoma: a randomized phase II trial. Annals of Oncology 2003, 14:97-104.
    • (2003) Annals of Oncology , vol.14 , pp. 97-104
    • Scheithauer, W.1    Schull, B.2    Ulrich-Pur, H.3
  • 22
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • Rocha Lima C.M., Green M.R., Rotche R., et al. Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. Journal of Clinical Oncology 2004, 22:3776-3783.
    • (2004) Journal of Clinical Oncology , vol.22 , pp. 3776-3783
    • Rocha Lima, C.M.1    Green, M.R.2    Rotche, R.3
  • 23
    • 20644464360 scopus 로고    scopus 로고
    • Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase III trial
    • Louvet C., Labianca R., Hammel P., et al. Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase III trial. Journal of Clinical Oncology 2005, 23:3509-3516.
    • (2005) Journal of Clinical Oncology , vol.23 , pp. 3509-3516
    • Louvet, C.1    Labianca, R.2    Hammel, P.3
  • 24
    • 19944409357 scopus 로고    scopus 로고
    • Gemcitabine versus cisplatin, epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: a randomised controlled multicentre phase III trial
    • Reni M., Cordio S., Milandri C., et al. Gemcitabine versus cisplatin, epirubicin, fluorouracil, and gemcitabine in advanced pancreatic cancer: a randomised controlled multicentre phase III trial. Lancet Oncology 2005, 6:369-376.
    • (2005) Lancet Oncology , vol.6 , pp. 369-376
    • Reni, M.1    Cordio, S.2    Milandri, C.3
  • 25
    • 23644437797 scopus 로고    scopus 로고
    • Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: a randomised phase II trial of the Italian oncology group for clinical research (GOIRC)
    • Di Costanzo F., Carlini P., Doni L., et al. Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: a randomised phase II trial of the Italian oncology group for clinical research (GOIRC). British Journal of Cancer 2005, 93:185-189.
    • (2005) British Journal of Cancer , vol.93 , pp. 185-189
    • Di Costanzo, F.1    Carlini, P.2    Doni, L.3
  • 26
    • 27144530079 scopus 로고    scopus 로고
    • A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer
    • Oettle H., Richards D., Ramanathan R.K., et al. A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancer. Annals of Oncology 2005, 16:1639-1645.
    • (2005) Annals of Oncology , vol.16 , pp. 1639-1645
    • Oettle, H.1    Richards, D.2    Ramanathan, R.K.3
  • 27
    • 33748445708 scopus 로고    scopus 로고
    • Randomized phase III trial of gemcitabine plus cisplatin compared with gemcitabine alone in advanced pancreatic cancer
    • Heinemann V., Quietzsch D., Gieseler F., et al. Randomized phase III trial of gemcitabine plus cisplatin compared with gemcitabine alone in advanced pancreatic cancer. Journal of Clinical Oncology 2006, 24:3946-3952.
    • (2006) Journal of Clinical Oncology , vol.24 , pp. 3946-3952
    • Heinemann, V.1    Quietzsch, D.2    Gieseler, F.3
  • 28
    • 33748297529 scopus 로고    scopus 로고
    • A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancer
    • Stathopoulos G.P., Syrigos K., Aravantinos G., et al. A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancer. British Journal of Cancer 2006, 95:587-592.
    • (2006) British Journal of Cancer , vol.95 , pp. 587-592
    • Stathopoulos, G.P.1    Syrigos, K.2    Aravantinos, G.3
  • 29
    • 68949114505 scopus 로고    scopus 로고
    • Phase III, randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed-dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology Group
    • Poplin E., Feng Y., Berlin J., et al. Phase III, randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed-dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology Group. Journal of Clinical Oncology 2009, 27:3778-3785.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 3778-3785
    • Poplin, E.1    Feng, Y.2    Berlin, J.3
  • 30
    • 33749071359 scopus 로고    scopus 로고
    • Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer
    • Abou-Alfa G.K., Letourneau R., Harker G., et al. Randomized phase III study of exatecan and gemcitabine compared with gemcitabine alone in untreated advanced pancreatic cancer. Journal of Clinical Oncology 2006, 24:4441-4447.
    • (2006) Journal of Clinical Oncology , vol.24 , pp. 4441-4447
    • Abou-Alfa, G.K.1    Letourneau, R.2    Harker, G.3
  • 31
    • 34250180939 scopus 로고    scopus 로고
    • Gemcitabine plus capecitabine compared with gemcitabine alone in advanced pancreatic cancer: a randomized, multicenter, phase III trial of the Swiss Group for Clinical Cancer Research and the Central European Cooperative Oncology Group
    • Herrmann R., Bodoky G., Ruhstaller T., et al. Gemcitabine plus capecitabine compared with gemcitabine alone in advanced pancreatic cancer: a randomized, multicenter, phase III trial of the Swiss Group for Clinical Cancer Research and the Central European Cooperative Oncology Group. Journal of Clinical Oncology 2007, 25:2212-2217.
    • (2007) Journal of Clinical Oncology , vol.25 , pp. 2212-2217
    • Herrmann, R.1    Bodoky, G.2    Ruhstaller, T.3
  • 32
    • 73949135518 scopus 로고    scopus 로고
    • Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer
    • Cunningham D., Chau I., Stocken D.D., et al. Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancer. Journal of Clinical Oncology 2009, 27:5513-5518.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 5513-5518
    • Cunningham, D.1    Chau, I.2    Stocken, D.D.3
  • 33
    • 77950498286 scopus 로고    scopus 로고
    • Randomized phase III trial of gemcitabine plus cisplatin compared with single-agent gemcitabine as first-line treatment of patients with advanced pancreatic cancer: the GIP-1 study
    • Colucci G., Labianca R., Di Costanzo F., et al. Randomized phase III trial of gemcitabine plus cisplatin compared with single-agent gemcitabine as first-line treatment of patients with advanced pancreatic cancer: the GIP-1 study. Journal of Clinical Oncology 2010, 28:1645-1651.
    • (2010) Journal of Clinical Oncology , vol.28 , pp. 1645-1651
    • Colucci, G.1    Labianca, R.2    Di Costanzo, F.3
  • 34
    • 73949094909 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer: CALGB 89904
    • Kulke M.H., Tempero M.A., Niedzwiecki D., et al. Randomized phase II study of gemcitabine administered at a fixed dose rate or in combination with cisplatin, docetaxel, or irinotecan in patients with metastatic pancreatic cancer: CALGB 89904. Journal of Clinical Oncology 2009, 27:5506-5512.
    • (2009) Journal of Clinical Oncology , vol.27 , pp. 5506-5512
    • Kulke, M.H.1    Tempero, M.A.2    Niedzwiecki, D.3
  • 35
    • 78049497383 scopus 로고    scopus 로고
    • Combination 5-fluorouracil, folinic acid and cisplatin (LV5FU2-CDDP) followed by gemcitabine or the reverse sequence in metastatic pancreatic cancer: final results of a randomised strategic phase III trial (FFCD 0301)
    • Dahan L., Bonnetain F., Ychou M., et al. Combination 5-fluorouracil, folinic acid and cisplatin (LV5FU2-CDDP) followed by gemcitabine or the reverse sequence in metastatic pancreatic cancer: final results of a randomised strategic phase III trial (FFCD 0301). Gut 2010, 59:1527-1534.
    • (2010) Gut , vol.59 , pp. 1527-1534
    • Dahan, L.1    Bonnetain, F.2    Ychou, M.3
  • 36
    • 84862006429 scopus 로고    scopus 로고
    • A multicentre randomised phase II trial of gemcitabine alone vs gemcitabine and S-1 combination therapy in advanced pancreatic cancer: GEMSAP study
    • Nakai Y., Isayama H., Sasaki T., et al. A multicentre randomised phase II trial of gemcitabine alone vs gemcitabine and S-1 combination therapy in advanced pancreatic cancer: GEMSAP study. British Journal of Cancer 2012, 106:1934-1939.
    • (2012) British Journal of Cancer , vol.106 , pp. 1934-1939
    • Nakai, Y.1    Isayama, H.2    Sasaki, T.3
  • 37
    • 84860463458 scopus 로고    scopus 로고
    • Cationic liposomal paclitaxel plus gemcitabine or gemcitabine alone in patients with advanced pancreatic cancer: a randomized controlled phase II trial
    • Löhr J.M., Haas S.L., Bechstein W.O., et al. Cationic liposomal paclitaxel plus gemcitabine or gemcitabine alone in patients with advanced pancreatic cancer: a randomized controlled phase II trial. Annals of Oncology 2012, 23:1214-1222.
    • (2012) Annals of Oncology , vol.23 , pp. 1214-1222
    • Löhr, J.M.1    Haas, S.L.2    Bechstein, W.O.3
  • 38
    • 84862290986 scopus 로고    scopus 로고
    • Randomized phase II study of gemcitabine and S-1 combination versus gemcitabine alone in the treatment of unresectable advanced pancreatic cancer (Japan Clinical Cancer Research Organization PC-01 study)
    • Ozaka M., Matsumura Y., Ishii H., et al. Randomized phase II study of gemcitabine and S-1 combination versus gemcitabine alone in the treatment of unresectable advanced pancreatic cancer (Japan Clinical Cancer Research Organization PC-01 study). Cancer Chemotherapy and Pharmacology 2012, 69:1197-1204.
    • (2012) Cancer Chemotherapy and Pharmacology , vol.69 , pp. 1197-1204
    • Ozaka, M.1    Matsumura, Y.2    Ishii, H.3
  • 39
    • 84880047829 scopus 로고    scopus 로고
    • Randomized phase III study of gemcitabine plus S-1, S-1 alone, or gemcitabine alone in patients with locally advanced and metastatic pancreatic cancer in Japan and Taiwan: GEST study
    • Ueno H., Ioka T., Ikeda M., et al. Randomized phase III study of gemcitabine plus S-1, S-1 alone, or gemcitabine alone in patients with locally advanced and metastatic pancreatic cancer in Japan and Taiwan: GEST study. Journal of Clinical Oncology 2013, 31:1640-1648.
    • (2013) Journal of Clinical Oncology , vol.31 , pp. 1640-1648
    • Ueno, H.1    Ioka, T.2    Ikeda, M.3
  • 40
    • 84872208571 scopus 로고    scopus 로고
    • FOLFIRI.3 (CPT-11 plus folinic acid plus 5-FU) alternating with gemcitabine or gemcitabine (G) alone in patients (pts) with previously untreated metastatic pancreatic adenocarcinoma (MPA): results of the randomized multicenter AGEO phase II trial FIRGEM
    • (abstr. 4018)
    • Trouilloud I., Dupont-Gossard A.C., Lecomte T., et al. FOLFIRI.3 (CPT-11 plus folinic acid plus 5-FU) alternating with gemcitabine or gemcitabine (G) alone in patients (pts) with previously untreated metastatic pancreatic adenocarcinoma (MPA): results of the randomized multicenter AGEO phase II trial FIRGEM. Journal of Clinical Oncology 2012, 30. (abstr. 4018).
    • (2012) Journal of Clinical Oncology , vol.30
    • Trouilloud, I.1    Dupont-Gossard, A.C.2    Lecomte, T.3
  • 41
    • 0035371228 scopus 로고    scopus 로고
    • Correlation between progression free survival and response rate in patients with metastatic colorectal carcinoma
    • Louvet C., de Gramont A., Tournigand C., et al. Correlation between progression free survival and response rate in patients with metastatic colorectal carcinoma. Cancer 2001, 91:2033-2038.
    • (2001) Cancer , vol.91 , pp. 2033-2038
    • Louvet, C.1    de Gramont, A.2    Tournigand, C.3
  • 42
    • 84874912760 scopus 로고    scopus 로고
    • Evaluation of progression-free survival as a surrogate endpoint for survival in chemotherapy and targeted agent metastatic colorectal cancer trials
    • Sidhu R., Rong A., Dahlberg S. Evaluation of progression-free survival as a surrogate endpoint for survival in chemotherapy and targeted agent metastatic colorectal cancer trials. Clinical Cancer Research 2013, 19:969-976.
    • (2013) Clinical Cancer Research , vol.19 , pp. 969-976
    • Sidhu, R.1    Rong, A.2    Dahlberg, S.3
  • 43
    • 33750610513 scopus 로고    scopus 로고
    • Correlation between tumor response to first-line chemotherapy and prognosis in advanced gastric cancer patients
    • Ichikawa W., Sasaki Y. Correlation between tumor response to first-line chemotherapy and prognosis in advanced gastric cancer patients. Annals of Oncology 2006, 17:1665-1672.
    • (2006) Annals of Oncology , vol.17 , pp. 1665-1672
    • Ichikawa, W.1    Sasaki, Y.2
  • 44
    • 84871186668 scopus 로고    scopus 로고
    • Optimizing supportive measures for the safe administration of FOLFIRINOX as first-line treatment in advanced, inoperable pancreatic cancer (aPDAC) patients (pts) in routine clinical practice
    • (abstr. e14661)
    • Vaccaro V., Bria E., Sperduti I., et al. Optimizing supportive measures for the safe administration of FOLFIRINOX as first-line treatment in advanced, inoperable pancreatic cancer (aPDAC) patients (pts) in routine clinical practice. Journal of Clinical Oncology 2012, 30. (abstr. e14661).
    • (2012) Journal of Clinical Oncology , vol.30
    • Vaccaro, V.1    Bria, E.2    Sperduti, I.3
  • 45
    • 83355169753 scopus 로고    scopus 로고
    • Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a Phase I/II trial
    • Von Hoff D.D., Ramanathan R.K., Borad M.J., et al. Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a Phase I/II trial. Journal of Clinical Oncology 2011, 29:4548-4554.
    • (2011) Journal of Clinical Oncology , vol.29 , pp. 4548-4554
    • Von Hoff, D.D.1    Ramanathan, R.K.2    Borad, M.J.3
  • 46
    • 84865474189 scopus 로고    scopus 로고
    • Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma
    • Maréchal R., Bachet J.B., Mackey J.R., et al. Levels of gemcitabine transport and metabolism proteins predict survival times of patients treated with gemcitabine for pancreatic adenocarcinoma. Gastroenterology 2012, 143:664-674.
    • (2012) Gastroenterology , vol.143 , pp. 664-674
    • Maréchal, R.1    Bachet, J.B.2    Mackey, J.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.