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Volumn 31, Issue 3, 2014, Pages 289-317

Incorporating incretin-based therapies into clinical practice for patients with type 2 diabetes

Author keywords

Dipeptidyl peptidase 4 inhibitors; Endocrinology; Glucagon like peptide 1 receptor agonists; Glycemic control; Incretin; Type 2 diabetes; Weight loss

Indexed keywords

DIPEPTIDYL PEPTIDASE IV INHIBITOR; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; INCRETIN; INSULIN; METFORMIN; SULFONYLUREA; ADAMANTANE; ALOGLIPTIN; ANTIDIABETIC AGENT; DIPEPTIDE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCAGON RECEPTOR; GLUCAGON-LIKE PEPTIDE-1 RECEPTOR; LINAGLIPTIN; LIRAGLUTIDE; PEPTIDE; PIPERIDINE DERIVATIVE; PURINE DERIVATIVE; PYRAZINE DERIVATIVE; QUINAZOLINE DERIVATIVE; SAXAGLIPTIN; SITAGLIPTIN; TRIAZOLE DERIVATIVE; URACIL; VENOM;

EID: 84898886425     PISSN: 0741238X     EISSN: 18658652     Source Type: Journal    
DOI: 10.1007/s12325-014-0100-5     Document Type: Review
Times cited : (8)

References (81)
  • 1
    • 67049155251 scopus 로고    scopus 로고
    • Unraveling the science of incretin biology
    • 19464426 10.1016/j.amjmed.2009.03.012
    • Nauck MA. Unraveling the science of incretin biology. Am J Med. 2009;122:S3-10.
    • (2009) Am J Med , vol.122
    • Nauck, M.A.1
  • 2
    • 84865464426 scopus 로고    scopus 로고
    • The role of endogenous incretin secretion as amplifier of glucose-stimulated insulin secretion in healthy subjects and patients with type 2 diabetes
    • 1:CAS:528:DC%2BC38XhtlantbbL 3425423 22721966 10.2337/db11-1701
    • Woerle HJ, Carneiro L, Derani A, Goke B, Schirra J. The role of endogenous incretin secretion as amplifier of glucose-stimulated insulin secretion in healthy subjects and patients with type 2 diabetes. Diabetes. 2012;61:2349-58.
    • (2012) Diabetes , vol.61 , pp. 2349-2358
    • Woerle, H.J.1    Carneiro, L.2    Derani, A.3    Goke, B.4    Schirra, J.5
  • 3
    • 84866268783 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes: A patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
    • 1:CAS:528:DC%2BC38Xps1Kitb4%3D 3357214 22517736 10.2337/dc12-0413
    • Inzucchi SE, Bergenstal RM, Buse JB, et al. Management of hyperglycemia in type 2 diabetes: a patient-centered approach. Position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2012;35:1364-79.
    • (2012) Diabetes Care , vol.35 , pp. 1364-1379
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3
  • 4
    • 75549091263 scopus 로고    scopus 로고
    • Statement by an American Association of Clinical Endocrinologists/ American College of Endocrinology consensus panel on type 2 diabetes mellitus: An algorithm for glycemic control
    • 19858063 10.4158/EP.15.6.540
    • Rodbard HW, Jellinger PS, Davidson JA, et al. Statement by an American Association of Clinical Endocrinologists/American College of Endocrinology consensus panel on type 2 diabetes mellitus: an algorithm for glycemic control. Endocr Pract. 2009;15:540-59.
    • (2009) Endocr Pract. , vol.15 , pp. 540-559
    • Rodbard, H.W.1    Jellinger, P.S.2    Davidson, J.A.3
  • 5
    • 84898862494 scopus 로고    scopus 로고
    • ® (exenatide) injection [prescribing information]. Princeton: Bristol-Myers Squibb Company; 2011
    • ® (exenatide) injection [prescribing information]. Princeton: Bristol-Myers Squibb Company; 2011.
  • 6
    • 84898844284 scopus 로고    scopus 로고
    • ® (exenatide extended-release for injectable suspension) [prescribing information]. Princeton: Bristol-Myers Squibb Company; 2012
    • ® (exenatide extended-release for injectable suspension) [prescribing information]. Princeton: Bristol-Myers Squibb Company; 2012.
  • 7
    • 84898868218 scopus 로고    scopus 로고
    • ® liraglutide (rDNA origin) injection [prescribing information]. Princeton: Novo Nordisk Inc.; 2013
    • ® liraglutide (rDNA origin) injection [prescribing information]. Princeton: Novo Nordisk Inc.; 2013.
  • 8
    • 84898858211 scopus 로고    scopus 로고
    • ® (sitagliptin) tablets [prescribing information]. Whitehouse Station: Merck & Co., Inc.; 2012
    • ® (sitagliptin) tablets [prescribing information]. Whitehouse Station: Merck & Co., Inc.; 2012.
  • 9
    • 84898904201 scopus 로고    scopus 로고
    • ® (saxagliptin) tablets [prescribing information]. Princeton: Bristol-Myers Squibb Company; 2011
    • ® (saxagliptin) tablets [prescribing information]. Princeton: Bristol-Myers Squibb Company; 2011.
  • 10
    • 84898903460 scopus 로고    scopus 로고
    • ® (alogliptin) tablets [prescribing information]. Takeda Pharmaceuticals America, Inc.; 2013
    • ® (alogliptin) tablets [prescribing information]. Takeda Pharmaceuticals America, Inc.; 2013.
  • 11
    • 84898839266 scopus 로고    scopus 로고
    • ® (linagliptin) [prescribing information]. Ridgefield: Boehringer Ingelheim Pharmaceuticals, Inc.; 2012
    • ® (linagliptin) [prescribing information]. Ridgefield: Boehringer Ingelheim Pharmaceuticals, Inc.; 2012.
  • 12
    • 77952309372 scopus 로고    scopus 로고
    • Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: A 26-week, randomised, parallel-group, open-label trial
    • 1:CAS:528:DC%2BC3cXltFOmsLo%3D 20417856 10.1016/S0140-6736(10)60307-8
    • Pratley RE, Nauck M, Bailey T, et al. Liraglutide versus sitagliptin for patients with type 2 diabetes who did not have adequate glycaemic control with metformin: a 26-week, randomised, parallel-group, open-label trial. Lancet. 2010;375:1447-56.
    • (2010) Lancet , vol.375 , pp. 1447-1456
    • Pratley, R.E.1    Nauck, M.2    Bailey, T.3
  • 13
    • 79952755181 scopus 로고    scopus 로고
    • One year of liraglutide treatment offers sustained and more effective glycaemic control and weight reduction compared with sitagliptin, both in combination with metformin, in patients with type 2 diabetes: A randomised, parallel-group, open-label trial
    • 1:CAS:528:DC%2BC3MXktFeht7Y%3D 3085127 21355967 10.1111/j.1742-1241.2011. 02656.x
    • Pratley R, Nauck M, Bailey T, et al. One year of liraglutide treatment offers sustained and more effective glycaemic control and weight reduction compared with sitagliptin, both in combination with metformin, in patients with type 2 diabetes: a randomised, parallel-group, open-label trial. Int J Clin Pract. 2011;65:397-407.
    • (2011) Int J Clin Pract , vol.65 , pp. 397-407
    • Pratley, R.1    Nauck, M.2    Bailey, T.3
  • 14
    • 84866650686 scopus 로고    scopus 로고
    • Efficacy and safety of switching from the DPP-4 inhibitor sitagliptin to the human GLP-1 analog liraglutide after 52 weeks in metformin-treated patients with type 2 diabetes: A randomized, open-label trial
    • 1:CAS:528:DC%2BC38Xhs1Gks77F 3447855 22851600 10.2337/dc11-2113
    • Pratley RE, Nauck MA, Bailey T, et al. Efficacy and safety of switching from the DPP-4 inhibitor sitagliptin to the human GLP-1 analog liraglutide after 52 weeks in metformin-treated patients with type 2 diabetes: a randomized, open-label trial. Diabetes Care. 2012;35:1986-93.
    • (2012) Diabetes Care , vol.35 , pp. 1986-1993
    • Pratley, R.E.1    Nauck, M.A.2    Bailey, T.3
  • 15
    • 77955262909 scopus 로고    scopus 로고
    • Further improvement in postprandial glucose control when adding exenatide (EXE) or sitagliptin (SITA) to combination therapy with insulin glargine (GLAR) and metformin (MET): A proof-of-concept study
    • 1:CAS:528:DC%2BC3cXpslKhu7o%3D 2890351 20357372 10.2337/dc09-2191
    • Arnolds S, Dellweg S, Clair J, et al. Further improvement in postprandial glucose control when adding exenatide (EXE) or sitagliptin (SITA) to combination therapy with insulin glargine (GLAR) and metformin (MET): a proof-of-concept study. Diabetes Care. 2010;33:1509-15.
    • (2010) Diabetes Care , vol.33 , pp. 1509-1515
    • Arnolds, S.1    Dellweg, S.2    Clair, J.3
  • 16
    • 84867191797 scopus 로고    scopus 로고
    • A randomized non-inferiority study comparing the addition of exenatide twice daily to sitagliptin or switching from sitagliptin to exenatide twice daily in patients with Type 2 diabetes experiencing inadequate glycaemic control on metformin and sitagliptin
    • 1:CAS:528:DC%2BC3sXps1entA%3D%3D 22375612 10.1111/j.1464-5491.2012.03624. x
    • Violante R, Oliveira JH, Yoon KH, et al. A randomized non-inferiority study comparing the addition of exenatide twice daily to sitagliptin or switching from sitagliptin to exenatide twice daily in patients with Type 2 diabetes experiencing inadequate glycaemic control on metformin and sitagliptin. Diabet Med. 2012;29:e417-24.
    • (2012) Diabet Med , vol.29
    • Violante, R.1    Oliveira, J.H.2    Yoon, K.H.3
  • 17
    • 55549136417 scopus 로고    scopus 로고
    • Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: A randomized, cross-over study
    • 1:CAS:528:DC%2BD1cXhsVKmt73K 18786299 10.1185/03007990802418851
    • DeFronzo RA, Okerson T, Viswanathan P, et al. Effects of exenatide versus sitagliptin on postprandial glucose, insulin and glucagon secretion, gastric emptying, and caloric intake: a randomized, cross-over study. Curr Med Res Opin. 2008;24:2943-52.
    • (2008) Curr Med Res Opin. , vol.24 , pp. 2943-2952
    • Defronzo, R.A.1    Okerson, T.2    Viswanathan, P.3
  • 18
    • 80053390364 scopus 로고    scopus 로고
    • Effects of exenatide twice daily versus sitagliptin on 24-hour glucose, glucoregulatory, and hormonal measures: A randomized, double-blind, crossover study
    • 1:CAS:528:DC%2BC3MXhsVOjsrbM 3258427 21615670 10.1111/j.1463-1326.2011. 01428.x
    • Berg JK, Shenouda SK, Heilmann CR, Gray AL, Holcombe JH. Effects of exenatide twice daily versus sitagliptin on 24-hour glucose, glucoregulatory, and hormonal measures: a randomized, double-blind, crossover study. Diabetes Obes Metab. 2011;13:982-9.
    • (2011) Diabetes Obes Metab. , vol.13 , pp. 982-989
    • Berg, J.K.1    Shenouda, S.K.2    Heilmann, C.R.3    Gray, A.L.4    Holcombe, J.H.5
  • 19
    • 77955573674 scopus 로고    scopus 로고
    • Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): A randomised trial
    • 20580422 10.1016/S0140-6736(10)60590-9
    • Bergenstal RM, Wysham C, Macconell L, et al. Efficacy and safety of exenatide once weekly versus sitagliptin or pioglitazone as an adjunct to metformin for treatment of type 2 diabetes (DURATION-2): a randomised trial. Lancet. 2010;376:431-9.
    • (2010) Lancet , vol.376 , pp. 431-439
    • Bergenstal, R.M.1    Wysham, C.2    Macconell, L.3
  • 20
    • 79955960213 scopus 로고    scopus 로고
    • DURATION-2: Efficacy and safety of switching from maximum daily sitagliptin or pioglitazone to once-weekly exenatide
    • 1:CAS:528:DC%2BC3MXos1Kmsrw%3D 3123706 21434995 10.1111/j.1464-5491.2011. 03301.x
    • Wysham C, Bergenstal R, Malloy J, et al. DURATION-2: efficacy and safety of switching from maximum daily sitagliptin or pioglitazone to once-weekly exenatide. Diabet Med. 2011;28:705-14.
    • (2011) Diabet Med. , vol.28 , pp. 705-714
    • Wysham, C.1    Bergenstal, R.2    Malloy, J.3
  • 21
    • 84859013614 scopus 로고    scopus 로고
    • Efficacy and safety of exenatide once weekly versus metformin, pioglitazone, and sitagliptin used as monotherapy in drug-naive patients with type 2 diabetes (DURATION-4): A 26-week double-blind study
    • 1:CAS:528:DC%2BC38Xjt1ajurw%3D 3263915 22210563 10.2337/dc11-1107
    • Russell-Jones D, Cuddihy RM, Hanefeld M, et al. Efficacy and safety of exenatide once weekly versus metformin, pioglitazone, and sitagliptin used as monotherapy in drug-naive patients with type 2 diabetes (DURATION-4): a 26-week double-blind study. Diabetes Care. 2012;35:252-8.
    • (2012) Diabetes Care. , vol.35 , pp. 252-258
    • Russell-Jones, D.1    Cuddihy, R.M.2    Hanefeld, M.3
  • 22
    • 67649666737 scopus 로고    scopus 로고
    • Liraglutide once a day versus exenatide twice a day for type 2 diabetes: A 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6)
    • 1:CAS:528:DC%2BD1MXotFCgtb4%3D 19515413 10.1016/S0140-6736(09)60659-0
    • Buse JB, Rosenstock J, Sesti G, et al. Liraglutide once a day versus exenatide twice a day for type 2 diabetes: a 26-week randomised, parallel-group, multinational, open-label trial (LEAD-6). Lancet. 2009;374:39-47.
    • (2009) Lancet , vol.374 , pp. 39-47
    • Buse, J.B.1    Rosenstock, J.2    Sesti, G.3
  • 23
    • 77956076972 scopus 로고    scopus 로고
    • Switching to once-daily liraglutide from twice-daily exenatide further improves glycemic control in patients with type 2 diabetes using oral agents
    • 1:CAS:528:DC%2BC3cXotFKhs7s%3D 2875443 20332351 10.2337/dc09-2260
    • Buse JB, Sesti G, Schmidt WE, et al. Switching to once-daily liraglutide from twice-daily exenatide further improves glycemic control in patients with type 2 diabetes using oral agents. Diabetes Care. 2010;33:1300-3.
    • (2010) Diabetes Care. , vol.33 , pp. 1300-1303
    • Buse, J.B.1    Sesti, G.2    Schmidt, W.E.3
  • 24
    • 84872084453 scopus 로고    scopus 로고
    • Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): A randomised, open-label study
    • 1:CAS:528:DC%2BC38Xhs1CjsbvM 23141817 10.1016/S0140-6736(12)61267-7
    • Buse JB, Nauck M, Forst T, et al. Exenatide once weekly versus liraglutide once daily in patients with type 2 diabetes (DURATION-6): a randomised, open-label study. Lancet. 2013;381:117-24.
    • (2013) Lancet. , vol.381 , pp. 117-124
    • Buse, J.B.1    Nauck, M.2    Forst, T.3
  • 25
    • 53249142132 scopus 로고    scopus 로고
    • Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: A randomised, open-label, non-inferiority study
    • 1:CAS:528:DC%2BD1cXhtF2ku7nN 18782641 10.1016/S0140-6736(08)61206-4
    • Drucker DJ, Buse JB, Taylor K, et al. Exenatide once weekly versus twice daily for the treatment of type 2 diabetes: a randomised, open-label, non-inferiority study. Lancet. 2008;372:1240-50.
    • (2008) Lancet , vol.372 , pp. 1240-1250
    • Drucker, D.J.1    Buse, J.B.2    Taylor, K.3
  • 26
    • 77953828230 scopus 로고    scopus 로고
    • DURATION-1: Exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks
    • 1:CAS:528:DC%2BC3cXotFKhsrY%3D 2875434 20215461 10.2337/dc09-1914
    • Buse JB, Drucker DJ, Taylor KL, et al. DURATION-1: exenatide once weekly produces sustained glycemic control and weight loss over 52 weeks. Diabetes Care. 2010;33:1255-61.
    • (2010) Diabetes Care. , vol.33 , pp. 1255-1261
    • Buse, J.B.1    Drucker, D.J.2    Taylor, K.L.3
  • 27
    • 79955661908 scopus 로고    scopus 로고
    • DURATION-5: Exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes
    • 1:CAS:528:DC%2BC3MXmsVWnsro%3D 21307137 10.1210/jc.2010-2081
    • Blevins T, Pullman J, Malloy J, et al. DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes. J Clin Endocrinol Metab. 2011;96:1301-10.
    • (2011) J Clin Endocrinol Metab. , vol.96 , pp. 1301-1310
    • Blevins, T.1    Pullman, J.2    Malloy, J.3
  • 28
    • 84862903186 scopus 로고    scopus 로고
    • Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets
    • 1:CAS:528:DC%2BC38Xht1Sht7rE 3379583 22584132 10.2337/dc11-1928
    • DeVries JH, Bain SC, Rodbard HW, et al. Sequential intensification of metformin treatment in type 2 diabetes with liraglutide followed by randomized addition of basal insulin prompted by A1C targets. Diabetes Care. 2012;35:1446-54.
    • (2012) Diabetes Care. , vol.35 , pp. 1446-1454
    • Devries, J.H.1    Bain, S.C.2    Rodbard, H.W.3
  • 29
    • 79551615182 scopus 로고    scopus 로고
    • Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes: A randomized, controlled trial
    • 21138825 10.7326/0003-4819-154-2-201101180-00300
    • Buse JB, Bergenstal RM, Glass LC, et al. Use of twice-daily exenatide in basal insulin-treated patients with type 2 diabetes: a randomized, controlled trial. Ann Intern Med. 2011;154:103-12.
    • (2011) Ann Intern Med. , vol.154 , pp. 103-112
    • Buse, J.B.1    Bergenstal, R.M.2    Glass, L.C.3
  • 30
    • 84873864348 scopus 로고    scopus 로고
    • Long-term efficacy and safety of linagliptin in patients with type 2 diabetes and severe renal impairment: A 1-year, randomized, double-blind, placebo-controlled study
    • 1:CAS:528:DC%2BC3sXislyju7s%3D 3554278 23033241 10.2337/dc12-0706
    • McGill JB, Sloan L, Newman J, et al. Long-term efficacy and safety of linagliptin in patients with type 2 diabetes and severe renal impairment: a 1-year, randomized, double-blind, placebo-controlled study. Diabetes Care. 2013;36:237-44.
    • (2013) Diabetes Care. , vol.36 , pp. 237-244
    • McGill, J.B.1    Sloan, L.2    Newman, J.3
  • 31
    • 84864373418 scopus 로고    scopus 로고
    • Comparison between sitagliptin as add-on therapy to insulin and insulin dose-increase therapy in uncontrolled Korean type 2 diabetes: CSI study
    • 1:CAS:528:DC%2BC38XhtFOmsLbF 22443183 10.1111/j.1463-1326.2012.01600.x
    • Hong ES, Khang AR, Yoon JW, et al. Comparison between sitagliptin as add-on therapy to insulin and insulin dose-increase therapy in uncontrolled Korean type 2 diabetes: CSI study. Diabetes Obes Metab. 2012;14:795-802.
    • (2012) Diabetes Obes Metab. , vol.14 , pp. 795-802
    • Hong, E.S.1    Khang, A.R.2    Yoon, J.W.3
  • 32
    • 73349119110 scopus 로고    scopus 로고
    • Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes
    • 1:STN:280:DC%2BC3c%2FkslGqsA%3D%3D 20092585 10.1111/j.1463-1326.2009. 01173.x
    • Vilsboll T, Rosenstock J, Yki-Jarvinen H, et al. Efficacy and safety of sitagliptin when added to insulin therapy in patients with type 2 diabetes. Diabetes Obes Metab. 2010;12:167-77.
    • (2010) Diabetes Obes Metab. , vol.12 , pp. 167-177
    • Vilsboll, T.1    Rosenstock, J.2    Yki-Jarvinen, H.3
  • 33
    • 84859731126 scopus 로고    scopus 로고
    • Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin
    • 1:CAS:528:DC%2BC38Xls1Whs7c%3D 22313154 10.1185/03007995.2012.665046
    • Barnett AH, Charbonnel B, Donovan M, Fleming D, Chen R. Effect of saxagliptin as add-on therapy in patients with poorly controlled type 2 diabetes on insulin alone or insulin combined with metformin. Curr Med Res Opin. 2012;28:513-23.
    • (2012) Curr Med Res Opin. , vol.28 , pp. 513-523
    • Barnett, A.H.1    Charbonnel, B.2    Donovan, M.3    Fleming, D.4    Chen, R.5
  • 34
    • 33846006173 scopus 로고    scopus 로고
    • The incretin system: Glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes
    • 1:CAS:528:DC%2BD28XhtF2gurjM 17098089 10.1016/S0140-6736(06)69705-5
    • Drucker DJ, Nauck MA. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet. 2006;368:1696-705.
    • (2006) Lancet. , vol.368 , pp. 1696-1705
    • Drucker, D.J.1    Nauck, M.A.2
  • 35
    • 80053203544 scopus 로고    scopus 로고
    • Drugs for diabetes: Part 5. DPP-4 inhibitors
    • McDougall C, McKay GA, Fisher M. Drugs for diabetes: part 5. DPP-4 inhibitors. Br J Cardiol. 2011;18:130-2.
    • (2011) Br J Cardiol. , vol.18 , pp. 130-132
    • McDougall, C.1    McKay, G.A.2    Fisher, M.3
  • 36
    • 77956893157 scopus 로고    scopus 로고
    • Liraglutide: The therapeutic promise from animal models
    • 1:CAS:528:DC%2BC3cXhtlaktb7E 10.1111/j.1742-1241.2010.02499.x
    • Knudsen LB. Liraglutide: the therapeutic promise from animal models. Int J Clin Pract Suppl. 2010;64:4-11.
    • (2010) Int J Clin Pract Suppl. , vol.64 , pp. 4-11
    • Knudsen, L.B.1
  • 37
    • 84863309250 scopus 로고    scopus 로고
    • Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes - A review and meta analysis
    • 1:CAS:528:DC%2BC38XhtlGhtL%2FL 22471248 10.1111/j.1463-1326.2012.01603.x
    • Deacon CF, Mannucci E, Ahren B. Glycaemic efficacy of glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors as add-on therapy to metformin in subjects with type 2 diabetes - a review and meta analysis. Diabetes Obes Metab. 2012;14:762-7.
    • (2012) Diabetes Obes Metab. , vol.14 , pp. 762-767
    • Deacon, C.F.1    Mannucci, E.2    Ahren, B.3
  • 38
    • 84858079439 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction
    • 22015237 10.1016/j.pcd.2011.09.002
    • Lind M, Jendle J, Torffvit O, Lager I. Glucagon-like peptide 1 (GLP-1) analogue combined with insulin reduces HbA1c and weight with low risk of hypoglycemia and high treatment satisfaction. Prim Care Diabetes. 2012;6:41-6.
    • (2012) Prim Care Diabetes. , vol.6 , pp. 41-46
    • Lind, M.1    Jendle, J.2    Torffvit, O.3    Lager, I.4
  • 39
    • 79955556781 scopus 로고    scopus 로고
    • The effect of liraglutide added to U-500 insulin in patients with type 2 diabetes and high insulin requirements
    • 1:CAS:528:DC%2BC3MXltlKjsbw%3D 21406014 10.1089/dia.2010.0221
    • Lane W, Weinrib S, Rappaport J. The effect of liraglutide added to U-500 insulin in patients with type 2 diabetes and high insulin requirements. Diabetes Technol Ther. 2011;13:592-5.
    • (2011) Diabetes Technol Ther. , vol.13 , pp. 592-595
    • Lane, W.1    Weinrib, S.2    Rappaport, J.3
  • 40
    • 84862109466 scopus 로고    scopus 로고
    • Baseline factors associated with glycemic control and weight loss when exenatide twice daily is added to optimized insulin glargine in patients with type 2 diabetes
    • 1:CAS:528:DC%2BC38XptVahsLs%3D 3329851 22432107 10.2337/dc11-1434
    • Rosenstock J, Shenouda SK, Bergenstal RM, et al. Baseline factors associated with glycemic control and weight loss when exenatide twice daily is added to optimized insulin glargine in patients with type 2 diabetes. Diabetes Care. 2012;35:955-8.
    • (2012) Diabetes Care. , vol.35 , pp. 955-958
    • Rosenstock, J.1    Shenouda, S.K.2    Bergenstal, R.M.3
  • 41
    • 84857531976 scopus 로고    scopus 로고
    • Clinical outcomes using long-term combination therapy with insulin glargine and exenatide in patients with type 2 diabetes
    • Levin PA, Mersey JH, Zhou S, Bromberger LA. Clinical outcomes using long-term combination therapy with insulin glargine and exenatide in patients with type 2 diabetes. Endocr Pract. 2012;18:17-25.
    • (2012) Endocr Pract. , vol.18 , pp. 17-25
    • Levin, P.A.1    Mersey, J.H.2    Zhou, S.3    Bromberger, L.A.4
  • 42
    • 84863230184 scopus 로고    scopus 로고
    • Combination therapy with insulin glargine and exenatide: Real-world outcomes in patients with type 2 diabetes
    • 1:CAS:528:DC%2BC38XktVyrurg%3D 22216894 10.1185/03007995.2012.654850
    • Levin P, Wei W, Wang L, et al. Combination therapy with insulin glargine and exenatide: real-world outcomes in patients with type 2 diabetes. Curr Med Res Opin. 2012;28:439-46.
    • (2012) Curr Med Res Opin. , vol.28 , pp. 439-446
    • Levin, P.1    Wei, W.2    Wang, L.3
  • 43
    • 48949098988 scopus 로고    scopus 로고
    • Safety and efficacy of exenatide in combination with insulin in patients with type 2 diabetes mellitus
    • 18463034 10.4158/EP.14.3.285
    • Sheffield CA, Kane MP, Busch RS, et al. Safety and efficacy of exenatide in combination with insulin in patients with type 2 diabetes mellitus. Endocr Pract. 2008;14:285-92.
    • (2008) Endocr Pract. , vol.14 , pp. 285-292
    • Sheffield, C.A.1    Kane, M.P.2    Busch, R.S.3
  • 44
    • 84865861808 scopus 로고    scopus 로고
    • Differentiating among incretin therapies: A multiple-target approach to type 2 diabetes
    • 1:CAS:528:DC%2BC38Xht1yks7vL 22436069 10.1111/j.1365-2710.2012.01342.x
    • Cornell S. Differentiating among incretin therapies: a multiple-target approach to type 2 diabetes. J Clin Pharm Ther. 2012;37:510-24.
    • (2012) J Clin Pharm Ther. , vol.37 , pp. 510-524
    • Cornell, S.1
  • 45
    • 34447267513 scopus 로고    scopus 로고
    • Efficacy and safety of incretin therapy in type 2 diabetes: Systematic review and meta-analysis
    • 1:CAS:528:DC%2BD2sXnslSjuro%3D 17622601 10.1001/jama.298.2.194
    • Amori RE, Lau J, Pittas AG. Efficacy and safety of incretin therapy in type 2 diabetes: systematic review and meta-analysis. JAMA. 2007;298:194-206.
    • (2007) JAMA , vol.298 , pp. 194-206
    • Amori, R.E.1    Lau, J.2    Pittas, A.G.3
  • 46
    • 53749085064 scopus 로고    scopus 로고
    • Incretin-based therapies in type 2 diabetes mellitus
    • 1:CAS:528:DC%2BD1cXht1GmtbfF 2579648 18628530 10.1210/jc.2007-2109
    • Chia CW, Egan JM. Incretin-based therapies in type 2 diabetes mellitus. J Clin Endocrinol Metab. 2008;93:3703-16.
    • (2008) J Clin Endocrinol Metab. , vol.93 , pp. 3703-3716
    • Chia, C.W.1    Egan, J.M.2
  • 47
    • 77956581914 scopus 로고    scopus 로고
    • Incretin agents in type 2 diabetes
    • Ross SA, Ekoe JM. Incretin agents in type 2 diabetes. Can Fam Phys. 2010;56:639-48.
    • (2010) Can Fam Phys. , vol.56 , pp. 639-648
    • Ross, S.A.1    Ekoe, J.M.2
  • 48
    • 79956152024 scopus 로고    scopus 로고
    • Evidence-based medicine in practice
    • 1:STN:280:DC%2BC3Mrgs1Cqsw%3D%3D 21564434 10.1111/j.1742-1241.2011.02681. x
    • Duggal R, Menkes DB. Evidence-based medicine in practice. Int J Clin Pract. 2011;65:639-44.
    • (2011) Int J Clin Pract. , vol.65 , pp. 639-644
    • Duggal, R.1    Menkes, D.B.2
  • 49
    • 0030027092 scopus 로고    scopus 로고
    • Evidence based medicine: What it is and what it isn't
    • 1:STN:280:DyaK287ktF2itw%3D%3D 2349778 8555924 10.1136/bmj.312.7023.71
    • Sackett DL, Rosenberg WM, Gray JA, Haynes RB, Richardson WS. Evidence based medicine: what it is and what it isn't. BMJ. 1996;312:71-2.
    • (1996) BMJ. , vol.312 , pp. 71-72
    • Sackett, D.L.1    Rosenberg, W.M.2    Gray, J.A.3    Haynes, R.B.4    Richardson, W.S.5
  • 50
    • 84856740961 scopus 로고    scopus 로고
    • Oral pharmacologic treatment of type 2 diabetes mellitus: A clinical practice guideline from the American College of Physicians
    • 22312141 10.7326/0003-4819-156-3-201202070-00011
    • Qaseem A, Humphrey LL, Sweet DE, Starkey M, Shekelle P. Oral pharmacologic treatment of type 2 diabetes mellitus: a clinical practice guideline from the American College of Physicians. Ann Intern Med. 2012;156:218-31.
    • (2012) Ann Intern Med. , vol.156 , pp. 218-231
    • Qaseem, A.1    Humphrey, L.L.2    Sweet, D.E.3    Starkey, M.4    Shekelle, P.5
  • 51
    • 34547660561 scopus 로고    scopus 로고
    • Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes
    • 1:CAS:528:DC%2BD2sXpsleksr8%3D 17485570 10.2337/dc07-0627
    • Goldstein BJ, Feinglos MN, Lunceford JK, Johnson J, Williams-Herman DE. Effect of initial combination therapy with sitagliptin, a dipeptidyl peptidase-4 inhibitor, and metformin on glycemic control in patients with type 2 diabetes. Diabetes Care. 2007;30(8):1979-87.
    • (2007) Diabetes Care. , vol.30 , Issue.8 , pp. 1979-1987
    • Goldstein, B.J.1    Feinglos, M.N.2    Lunceford, J.K.3    Johnson, J.4    Williams-Herman, D.E.5
  • 52
    • 65549123794 scopus 로고    scopus 로고
    • Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: A randomized controlled trial
    • 1:CAS:528:DC%2BD1MXnslKrtbo%3D 19515181 10.1111/j.1463-1326.2009.01056.x
    • Jadzinsky M, Pfutzner A, Paz-Pacheco E, et al. Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial. Diabetes Obes Metab. 2009;11:611-22.
    • (2009) Diabetes Obes Metab. , vol.11 , pp. 611-622
    • Jadzinsky, M.1    Pfutzner, A.2    Paz-Pacheco, E.3
  • 53
    • 84862813117 scopus 로고    scopus 로고
    • Initial combination of linagliptin and metformin improves glycaemic control in type 2 diabetes: A randomised, double-blind, placebo-controlled study
    • 1:CAS:528:DC%2BC38XhtVSgsrvN 22356132 10.1111/j.1463-1326.2012.01590.x
    • Haak T, Meinicke T, Jones R, et al. Initial combination of linagliptin and metformin improves glycaemic control in type 2 diabetes: a randomised, double-blind, placebo-controlled study. Diabetes Obes Metab. 2012;14:565-74.
    • (2012) Diabetes Obes Metab. , vol.14 , pp. 565-574
    • Haak, T.1    Meinicke, T.2    Jones, R.3
  • 54
    • 18144401971 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes
    • 1:CAS:528:DC%2BD2MXksF2hu7g%3D 15855572 10.2337/diacare.28.5.1092
    • DeFronzo RA, Ratner RE, Han J, et al. Effects of exenatide (exendin-4) on glycemic control and weight over 30 weeks in metformin-treated patients with type 2 diabetes. Diabetes Care. 2005;28:1092-100.
    • (2005) Diabetes Care. , vol.28 , pp. 1092-1100
    • Defronzo, R.A.1    Ratner, R.E.2    Han, J.3
  • 55
    • 62449169287 scopus 로고    scopus 로고
    • Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: The LEAD (Liraglutide Effect and Action in Diabetes)-2 study
    • 1:CAS:528:DC%2BD1MXhs1Ggu7g%3D 2606836 18931095 10.2337/dc08-1355
    • Nauck M, Frid A, Hermansen K, et al. Efficacy and safety comparison of liraglutide, glimepiride, and placebo, all in combination with metformin, in type 2 diabetes: the LEAD (Liraglutide Effect and Action in Diabetes)-2 study. Diabetes Care. 2009;32:84-90.
    • (2009) Diabetes Care. , vol.32 , pp. 84-90
    • Nauck, M.1    Frid, A.2    Hermansen, K.3
  • 56
    • 84881486681 scopus 로고    scopus 로고
    • Liraglutide achieves A1C targets more often than sitagliptin or exenatide when added to metformin in patients with type 2 diabetes and a baseline A1C < 8.0%
    • 23186975 10.4158/EP12232.OR
    • King AB, Montanya E, Pratley RE, et al. Liraglutide achieves A1C targets more often than sitagliptin or exenatide when added to metformin in patients with type 2 diabetes and a baseline A1C < 8.0%. Endocr Pract. 2013;19:64-72.
    • (2013) Endocr Pract. , vol.19 , pp. 64-72
    • King, A.B.1    Montanya, E.2    Pratley, R.E.3
  • 57
    • 79959692519 scopus 로고    scopus 로고
    • Mild renal impairment and the efficacy and safety of liraglutide
    • 10.4158/EP10215.OR
    • Davidson JA, Brett J, Falahati A, Scott D. Mild renal impairment and the efficacy and safety of liraglutide. Endocr Pract. 2010;17:345-55.
    • (2010) Endocr Pract. , vol.17 , pp. 345-355
    • Davidson, J.A.1    Brett, J.2    Falahati, A.3    Scott, D.4
  • 58
    • 79951906623 scopus 로고    scopus 로고
    • Liraglutide, a once-daily human glucagon-like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes
    • 1:CAS:528:DC%2BC3MXktlylu70%3D 3084519 21205128 10.1111/j.1463-1326.2010. 01356.x
    • Garber A, Henry RR, Ratner R, et al. Liraglutide, a once-daily human glucagon-like peptide 1 analogue, provides sustained improvements in glycaemic control and weight for 2 years as monotherapy compared with glimepiride in patients with type 2 diabetes. Diabetes Obes Metab. 2011;13:348-56.
    • (2011) Diabetes Obes Metab. , vol.13 , pp. 348-356
    • Garber, A.1    Henry, R.R.2    Ratner, R.3
  • 59
    • 59449101432 scopus 로고    scopus 로고
    • Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): A randomised, 52-week, phase III, double-blind, parallel-treatment trial
    • 1:CAS:528:DC%2BD1MXhsFKgur0%3D 18819705 10.1016/S0140-6736(08)61246-5
    • Garber A, Henry R, Ratner R, et al. Liraglutide versus glimepiride monotherapy for type 2 diabetes (LEAD-3 Mono): a randomised, 52-week, phase III, double-blind, parallel-treatment trial. Lancet. 2009;373:473-81.
    • (2009) Lancet. , vol.373 , pp. 473-481
    • Garber, A.1    Henry, R.2    Ratner, R.3
  • 60
    • 84859721063 scopus 로고    scopus 로고
    • DPP-4 inhibitors in the management of type 2 diabetes: A critical review of head-to-head trials
    • 1:CAS:528:DC%2BC38XlvVSnuro%3D 22197148 10.1016/j.diabet.2011.11.001
    • Scheen AJ. DPP-4 inhibitors in the management of type 2 diabetes: a critical review of head-to-head trials. Diabetes Metab. 2012;38:89-101.
    • (2012) Diabetes Metab. , vol.38 , pp. 89-101
    • Scheen, A.J.1
  • 61
    • 79959484802 scopus 로고    scopus 로고
    • Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT
    • 1:CAS:528:DC%2BC3MXmsVKlu7w%3D 3292330 21415383 10.2337/db10-1392
    • Kahn SE, Lachin JM, Zinman B, et al. Effects of rosiglitazone, glyburide, and metformin on β-cell function and insulin sensitivity in ADOPT. Diabetes. 2011;60:1552-60.
    • (2011) Diabetes. , vol.60 , pp. 1552-1560
    • Kahn, S.E.1    Lachin, J.M.2    Zinman, B.3
  • 62
    • 33845405222 scopus 로고    scopus 로고
    • Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
    • 1:CAS:528:DC%2BD28Xht12ntrzF 17145742 10.1056/NEJMoa066224
    • Kahn SE, Haffner SM, Heise MA, et al. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med. 2006;355:2427-43.
    • (2006) N Engl J Med. , vol.355 , pp. 2427-2443
    • Kahn, S.E.1    Haffner, S.M.2    Heise, M.A.3
  • 63
    • 77951044560 scopus 로고    scopus 로고
    • Efficacy and safety of the once-daily human GLP-1 analogue, liraglutide, vs glibenclamide monotherapy in Japanese patients with type 2 diabetes
    • 1:CAS:528:DC%2BC3cXkslOju7k%3D 20199137 10.1185/03007991003672551
    • Seino Y, Rasmussen MF, Nishida T, Kaku K. Efficacy and safety of the once-daily human GLP-1 analogue, liraglutide, vs glibenclamide monotherapy in Japanese patients with type 2 diabetes. Curr Med Res Opin. 2010;26:1013-22.
    • (2010) Curr Med Res Opin. , vol.26 , pp. 1013-1022
    • Seino, Y.1    Rasmussen, M.F.2    Nishida, T.3    Kaku, K.4
  • 64
    • 68949212458 scopus 로고    scopus 로고
    • Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: A randomised controlled trial
    • 1:CAS:528:DC%2BC3cXksVeqsrg%3D 2779994 19614786 10.1111/j.1742-1241.2009. 02143.x
    • Chacra AR, Tan GH, Apanovitch A, et al. Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial. Int J Clin Pract. 2009;63:1395-406.
    • (2009) Int J Clin Pract. , vol.63 , pp. 1395-1406
    • Chacra, A.R.1    Tan, G.H.2    Apanovitch, A.3
  • 65
    • 84871995815 scopus 로고    scopus 로고
    • Standards of medical care in diabetes-2013
    • American Diabetes Association 3537269 10.2337/dc13-S011
    • American Diabetes Association. Standards of medical care in diabetes-2013. Diabetes Care. 2013;36(Suppl 1):S11-66.
    • (2013) Diabetes Care , vol.36 , Issue.SUPPL. 1
  • 66
    • 79960995890 scopus 로고    scopus 로고
    • Glucose-incretin interaction revisited
    • 1:CAS:528:DC%2BC3MXhsVCltL7J 21701075 10.1507/endocrj.EJ11-0064
    • Ishii H, Sato Y, Takei M, Nishio S, Komatsu M. Glucose-incretin interaction revisited. Endocr J. 2011;58:519-25.
    • (2011) Endocr J. , vol.58 , pp. 519-525
    • Ishii, H.1    Sato, Y.2    Takei, M.3    Nishio, S.4    Komatsu, M.5
  • 67
    • 62449129181 scopus 로고    scopus 로고
    • Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU)
    • 1:CAS:528:DC%2BD1MXkvVGqur8%3D 2871176 19317822 10.1111/j.1464-5491.2009. 02666.x
    • Marre M, Shaw J, Brandle M, et al. Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with type 2 diabetes (LEAD-1 SU). Diabet Med. 2009;26:268-78.
    • (2009) Diabet Med. , vol.26 , pp. 268-278
    • Marre, M.1    Shaw, J.2    Brandle, M.3
  • 68
    • 7444228521 scopus 로고    scopus 로고
    • Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes
    • 1:CAS:528:DC%2BD2cXhtVKis7zO 15504997 10.2337/diacare.27.11.2628
    • Buse JB, Henry RR, Han J, et al. Effects of exenatide (exendin-4) on glycemic control over 30 weeks in sulfonylurea-treated patients with type 2 diabetes. Diabetes Care. 2004;27:2628-35.
    • (2004) Diabetes Care. , vol.27 , pp. 2628-2635
    • Buse, J.B.1    Henry, R.R.2    Han, J.3
  • 69
    • 69949117621 scopus 로고    scopus 로고
    • Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus: A randomised controlled trial (LEAD-5 met + SU)
    • 1:CAS:528:DC%2BD1MXhtVygtLnE 2744824 19688338 10.1007/s00125-009-1472-y
    • Russell-Jones D, Vaag A, Schmitz O, et al. Liraglutide vs insulin glargine and placebo in combination with metformin and sulfonylurea therapy in type 2 diabetes mellitus: a randomised controlled trial (LEAD-5 met + SU). Diabetologia. 2009;52:2046-55.
    • (2009) Diabetologia. , vol.52 , pp. 2046-2055
    • Russell-Jones, D.1    Vaag, A.2    Schmitz, O.3
  • 70
    • 34247195226 scopus 로고    scopus 로고
    • A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: A non-inferiority study
    • 1:CAS:528:DC%2BD2sXitlSksA%3D%3D 17160407 10.1007/s00125-006-0510-2
    • Nauck MA, Duran S, Kim D, et al. A comparison of twice-daily exenatide and biphasic insulin aspart in patients with type 2 diabetes who were suboptimally controlled with sulfonylurea and metformin: a non-inferiority study. Diabetologia. 2007;50:259-67.
    • (2007) Diabetologia. , vol.50 , pp. 259-267
    • Nauck, M.A.1    Duran, S.2    Kim, D.3
  • 71
    • 34547863123 scopus 로고    scopus 로고
    • Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin
    • 1:CAS:528:DC%2BD2sXhtFGgt7vO 17593236 10.1111/j.1463-1326.2007.00744.x
    • Hermansen K, Kipnes M, Luo E, et al. Efficacy and safety of the dipeptidyl peptidase-4 inhibitor, sitagliptin, in patients with type 2 diabetes mellitus inadequately controlled on glimepiride alone or on glimepiride and metformin. Diabetes Obes Metab. 2007;9:733-45.
    • (2007) Diabetes Obes Metab. , vol.9 , pp. 733-745
    • Hermansen, K.1    Kipnes, M.2    Luo, E.3
  • 72
    • 64649104158 scopus 로고    scopus 로고
    • Banting lecture. from the triumvirate to the ominous octet: A new paradigm for the treatment of type 2 diabetes mellitus
    • 1:CAS:528:DC%2BD1MXktleitbw%3D 2661582 19336687 10.2337/db09-9028
    • DeFronzo RA. Banting lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus. Diabetes. 2009;58:773-95.
    • (2009) Diabetes. , vol.58 , pp. 773-795
    • Defronzo, R.A.1
  • 73
    • 67650066860 scopus 로고    scopus 로고
    • Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met + TZD)
    • 1:CAS:528:DC%2BD1MXps1KqsLs%3D 2699702 19289857 10.2337/dc08-2124
    • Zinman B, Gerich J, Buse JB, et al. Efficacy and safety of the human glucagon-like peptide-1 analog liraglutide in combination with metformin and thiazolidinedione in patients with type 2 diabetes (LEAD-4 Met + TZD). Diabetes Care. 2009;32:1224-30.
    • (2009) Diabetes Care. , vol.32 , pp. 1224-1230
    • Zinman, B.1    Gerich, J.2    Buse, J.B.3
  • 74
    • 79959559653 scopus 로고    scopus 로고
    • Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies
    • 1:CAS:528:DC%2BC3MXosVGnsrY%3D 21334333 10.1053/j.gastro.2011.02.018
    • Elashoff M, Matveyenko AV, Gier B, Elashoff R, Butler PC. Pancreatitis, pancreatic, and thyroid cancer with glucagon-like peptide-1-based therapies. Gastroenterology. 2011;141:150-6.
    • (2011) Gastroenterology. , vol.141 , pp. 150-156
    • Elashoff, M.1    Matveyenko, A.V.2    Gier, B.3    Elashoff, R.4    Butler, P.C.5
  • 75
    • 79960086290 scopus 로고    scopus 로고
    • The safety of incretin-based therapies - Review of the scientific evidence
    • 1:CAS:528:DC%2BC3MXptlSrsL0%3D 21734003 10.1210/jc.2011-0599
    • Drucker DJ, Sherman SI, Bergenstal RM, Buse JB. The safety of incretin-based therapies - review of the scientific evidence. J Clin Endocrinol Metab. 2011;96:2027-31.
    • (2011) J Clin Endocrinol Metab. , vol.96 , pp. 2027-2031
    • Drucker, D.J.1    Sherman, S.I.2    Bergenstal, R.M.3    Buse, J.B.4
  • 76
    • 84879231610 scopus 로고    scopus 로고
    • A critical analysis of the clinical use of incretin-based therapies: The benefits by far outweigh the potential risks
    • 23645884 10.2337/dc12-2504
    • Nauck MA. A critical analysis of the clinical use of incretin-based therapies: the benefits by far outweigh the potential risks. Diabetes Care. 2013;36:2126-32.
    • (2013) Diabetes Care. , vol.36 , pp. 2126-2132
    • Nauck, M.A.1
  • 77
    • 84878185729 scopus 로고    scopus 로고
    • A critical analysis of the clinical use of incretin-based therapies: Are the GLP-1 therapies safe?
    • 23645885 10.2337/dc12-2713
    • Butler PC, Elashoff M, Elashoff R, Gale EA. A critical analysis of the clinical use of incretin-based therapies: are the GLP-1 therapies safe? Diabetes Care. 2013;36:2118-25.
    • (2013) Diabetes Care. , vol.36 , pp. 2118-2125
    • Butler, P.C.1    Elashoff, M.2    Elashoff, R.3    Gale, E.A.4
  • 79
    • 79851495878 scopus 로고    scopus 로고
    • Liraglutide improves treatment satisfaction in people with type 2 diabetes compared with sitagliptin, each as an add on to metformin
    • 1:CAS:528:DC%2BC3MXktVGgur4%3D 21309842
    • Davies M, Pratley R, Hammer M, Thomsen AB, Cuddihy R. Liraglutide improves treatment satisfaction in people with type 2 diabetes compared with sitagliptin, each as an add on to metformin. Diabet Med. 2011;28:333-7.
    • (2011) Diabet Med. , vol.28 , pp. 333-337
    • Davies, M.1    Pratley, R.2    Hammer, M.3    Thomsen, A.B.4    Cuddihy, R.5
  • 80
    • 67649774247 scopus 로고    scopus 로고
    • Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily
    • 1:CAS:528:DC%2BD1MXpvFeksrY%3D 2776933 19573122 10.1111/j.1464-5491.2009. 02752.x
    • Best JH, Boye KS, Rubin RR, et al. Improved treatment satisfaction and weight-related quality of life with exenatide once weekly or twice daily. Diabet Med. 2009;26:722-8.
    • (2009) Diabet Med. , vol.26 , pp. 722-728
    • Best, J.H.1    Boye, K.S.2    Rubin, R.R.3
  • 81
    • 79951689950 scopus 로고    scopus 로고
    • Weight-related quality of life, health utility, psychological well-being, and satisfaction with exenatide once weekly compared with sitagliptin or pioglitazone after 26 weeks of treatment
    • 1:CAS:528:DC%2BC3MXis1Crtb8%3D 3024340 21270189 10.2337/dc10-1119
    • Best JH, Rubin RR, Peyrot M, et al. Weight-related quality of life, health utility, psychological well-being, and satisfaction with exenatide once weekly compared with sitagliptin or pioglitazone after 26 weeks of treatment. Diabetes Care. 2011;34:314-9.
    • (2011) Diabetes Care. , vol.34 , pp. 314-319
    • Best, J.H.1    Rubin, R.R.2    Peyrot, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.