메뉴 건너뛰기




Volumn 106, Issue 4, 2014, Pages

Better therapeutic trials in ovarian cancer

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA1 PROTEIN, HUMAN; BRCA2 PROTEIN; BRCA2 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84898857497     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/dju029     Document Type: Review
Times cited : (41)

References (38)
  • 1
    • 77649219639 scopus 로고    scopus 로고
    • The origin and pathogenesis of epithelial ovarian cancer-a proposed unifying theory
    • Kurman RJ, Shih IM. The origin and pathogenesis of epithelial ovarian cancer-a proposed unifying theory. Am J Surg Pathol. 2010;34(3):433.
    • (2010) Am J Surg Pathol. , vol.34 , Issue.3 , pp. 433
    • Kurman, R.J.1    Shih, I.M.2
  • 2
    • 0037454224 scopus 로고    scopus 로고
    • Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma
    • Singer G, Oldt R III, Cohen Y, et al. Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma. J Natl Cancer Inst. 2003;95(6):484-486.
    • (2003) J Natl Cancer Inst. , vol.95 , Issue.6 , pp. 484-486
    • Singer, G.1    Oldt Iii., R.2    Cohen, Y.3
  • 3
    • 1842581590 scopus 로고    scopus 로고
    • Grading ovarian serous carcinoma using a two-tier system
    • Malpica A, Deavers MT, Lu K, et al. Grading ovarian serous carcinoma using a two-tier system. Am J Surg Pathol. 2004;28(4):496.
    • (2004) Am J Surg Pathol. , vol.28 , Issue.4 , pp. 496
    • Malpica, A.1    Deavers, M.T.2    Lu, K.3
  • 4
    • 84867403944 scopus 로고    scopus 로고
    • Transitional cell carcinoma of the ovary is related to high-grade serous carcinoma and is distinct from malignant Brenner tumor
    • Ali RH, Seidman JD, Luk M, Kalloger S, Gilks CB. Transitional cell carcinoma of the ovary is related to high-grade serous carcinoma and is distinct from malignant Brenner tumor. Int J Gynecol Pathol. 2012;31(6):499-506
    • (2012) Int J Gynecol Pathol. , vol.31 , Issue.6 , pp. 499-506
    • Ali, R.H.1    Seidman, J.D.2    Luk, M.3    Kalloger, S.4    Gilks, C.B.5
  • 5
    • 47749086997 scopus 로고    scopus 로고
    • Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma
    • Gilks CB, Ionescu DN, Kalloger SE, et al. Tumor cell type can be reproducibly diagnosed and is of independent prognostic significance in patients with maximally debulked ovarian carcinoma. Hum Pathol. 2008;39(8):1239-1251.
    • (2008) Hum Pathol. , vol.39 , Issue.8 , pp. 1239-1251
    • Gilks, C.B.1    Ionescu, D.N.2    Kalloger, S.E.3
  • 6
    • 77954213625 scopus 로고    scopus 로고
    • Diagnosis of ovarian carcinoma cell type is highly reproducible: A transcanadian study
    • Köbel M, Kalloger SE, Baker PM, et al. Diagnosis of ovarian carcinoma cell type is highly reproducible: a transcanadian study. Am J Surg Pathol. 2010;34(7):984-993.
    • (2010) Am J Surg Pathol. , vol.34 , Issue.7 , pp. 984-993
    • Köbel, M.1    Kalloger, S.E.2    Baker, P.M.3
  • 7
    • 34547627444 scopus 로고    scopus 로고
    • Interobserver and intraobserver variability of a two-tier system for grading ovarian serous carcinoma
    • Malpica A, Deavers MT, Tornos C, et al. Interobserver and intraobserver variability of a two-tier system for grading ovarian serous carcinoma. Am J Surg Pathol. 2007;31(8):1168-1174.
    • (2007) Am J Surg Pathol. , vol.31 , Issue.8 , pp. 1168-1174
    • Malpica, A.1    Deavers, M.T.2    Tornos, C.3
  • 8
    • 67349190538 scopus 로고    scopus 로고
    • Precursors to pelvic serous carcinoma and their clinical implications
    • Folkins AK, Jarboe EA, Roh MH, Crum C P. Precursors to pelvic serous carcinoma and their clinical implications. Gynecol Oncol. 2009;113(3):391-396.
    • (2009) Gynecol Oncol. , vol.113 , Issue.3 , pp. 391-396
    • Folkins, A.K.1    Jarboe, E.A.2    Roh, M.H.3    Crum, C.P.4
  • 9
    • 0035175430 scopus 로고    scopus 로고
    • Dysplastic changes in prophy-lactically removed Fallopian tubes of women predisposed to developing ovarian cancer
    • Piek JM., van Diest PJ, Zweemer R P, et al. Dysplastic changes in prophy-lactically removed Fallopian tubes of women predisposed to developing ovarian cancer. J Pathol. 2001;195(4):451-456.
    • (2001) J Pathol. , vol.195 , Issue.4 , pp. 451-456
    • Piek, J.M.1    Van Diest, P.J.2    Zweemer, R.P.3
  • 10
    • 33846187651 scopus 로고    scopus 로고
    • A candidate precursor to serous carcinoma that originates in the distal fallopian tube
    • Lee Y, Miron A, Drapkin R, et al. A candidate precursor to serous carcinoma that originates in the distal fallopian tube. J Pathol. 2007;211(1):26-35.
    • (2007) J Pathol. , vol.211 , Issue.1 , pp. 26-35
    • Lee, Y.1    Miron, A.2    Drapkin, R.3
  • 11
    • 0028844106 scopus 로고
    • Endometrioid adenocarcinoma of the ovary and its relationship to endo-metriosis
    • McMeekin DS, Burger RA, Manetta A, DiSaia P, Berman ML. Endometrioid adenocarcinoma of the ovary and its relationship to endo-metriosis. Gynecol Oncol. 1995;59(1):81-86.
    • (1995) Gynecol Oncol. , vol.59 , Issue.1 , pp. 81-86
    • McMeekin, D.S.1    Burger, R.A.2    Manetta, A.3    Disaia, P.4    Berman, M.L.5
  • 13
    • 77957946398 scopus 로고    scopus 로고
    • ARID1A mutations in endometriosis-associated ovarian carcinomas
    • Wiegand KC, Shah SP, Al-Agha OM, et al. ARID1A mutations in endometriosis-associated ovarian carcinomas. N Engl J Med. 2010;363(16):1532- 1543.
    • (2010) N Engl J Med. , vol.363 , Issue.16 , pp. 1532-1543
    • Wiegand, K.C.1    Shah, S.P.2    Al-Agha, O.M.3
  • 14
    • 84866930983 scopus 로고    scopus 로고
    • New insights into the pathogen-esis of ovarian carcinoma: Time to rethink ovarian cancer screening
    • Chan A, Gilks CB, Kwon J, Tinker A. New insights into the pathogen-esis of ovarian carcinoma: time to rethink ovarian cancer screening. Obstet Gynecol. 2012;20(4):935-940.
    • (2012) Obstet Gynecol. , vol.20 , Issue.4 , pp. 935-940
    • Chan, A.1    Gilks, C.B.2    Kwon, J.3    Tinker, A.4
  • 15
    • 84872930026 scopus 로고    scopus 로고
    • BRAF mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer
    • Grisham RN, Iyer G, Garg K, et al. BRAF mutation is associated with early stage disease and improved outcome in patients with low-grade serous ovarian cancer. Cancer. 2013;119(3):548-554.
    • (2013) Cancer. , vol.119 , Issue.3 , pp. 548-554
    • Grisham, R.N.1    Iyer, G.2    Garg, K.3
  • 16
    • 77957354624 scopus 로고    scopus 로고
    • BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas
    • Wong KK, Tsang YT, Deavers MT, et al. BRAF mutation is rare in advanced-stage low-grade ovarian serous carcinomas. Am J Pathol. 2010;177(4):1611-1617.
    • (2010) Am J Pathol. , vol.177 , Issue.4 , pp. 1611-1617
    • Wong, K.K.1    Tsang, Y.T.2    Deavers, M.T.3
  • 17
    • 0033651234 scopus 로고    scopus 로고
    • The molecular and cellular biology of HER2/neu gene amplification/ overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer
    • Pegram MD, Konecny G, Slamon DJ. The molecular and cellular biology of HER2/neu gene amplification/overexpression and the clinical development of herceptin (trastuzumab) therapy for breast cancer. Cancer Treat Res. 2000;103:57-75.
    • (2000) Cancer Treat Res. , vol.103 , pp. 57-75
    • Pegram, M.D.1    Konecny, G.2    Slamon, D.J.3
  • 18
    • 78049425319 scopus 로고    scopus 로고
    • Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
    • Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010;363(18):1693-1703.
    • (2010) N Engl J Med. , vol.363 , Issue.18 , pp. 1693-1703
    • Kwak, E.L.1    Bang, Y.J.2    Camidge, D.R.3
  • 19
    • 84864026311 scopus 로고    scopus 로고
    • BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: A report from the Australian Ovarian Cancer Study Group
    • Alsop K, Fereday S, et al. BRCA mutation frequency and patterns of treatment response in BRCA mutation-positive women with ovarian cancer: a report from the Australian Ovarian Cancer Study Group. J Clin Oncol. 2012;30(21):2654-2663.
    • (2012) J Clin Oncol. , vol.30 , Issue.21 , pp. 2654-2663
    • Alsop, K.1    Fereday, S.2
  • 20
    • 67650471685 scopus 로고    scopus 로고
    • Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers
    • Fong PC, Boss DS, Yap TA, et al. Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers. N Engl J Med. 2009;361(2):123-134.
    • (2009) N Engl J Med. , vol.361 , Issue.2 , pp. 123-134
    • Fong, P.C.1    Boss, D.S.2    Yap, T.A.3
  • 21
    • 77955039099 scopus 로고    scopus 로고
    • Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: A proof-of-concept trial
    • Audeh MW, Carmichael J, Penson RT, et al. Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial. Lancet. 2010;376(9737):245- 251.
    • (2010) Lancet. , vol.376 , Issue.9737 , pp. 245-251
    • Audeh, M.W.1    Carmichael, J.2    Penson, R.T.3
  • 22
    • 80052389761 scopus 로고    scopus 로고
    • Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: A phase 2, multicentre, open-label, non-randomised study
    • Gelmon KA, Tischkowitz M, Mackay H, et al. Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study. Lancet Oncol. 2011;12(9):852-861.
    • (2011) Lancet Oncol. , vol.12 , Issue.9 , pp. 852-861
    • Gelmon, K.A.1    Tischkowitz, M.2    Mackay, H.3
  • 23
    • 84863010984 scopus 로고    scopus 로고
    • Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer
    • Kaye SB, Lubinski J, Matulonis U, et al. Phase II, open-label, randomized, multicenter study comparing the efficacy and safety of olaparib, a poly (ADP-ribose) polymerase inhibitor, and pegylated liposomal doxorubicin in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer. J Clin Oncol. 2012;30(4):372-379.
    • (2012) J Clin Oncol. , vol.30 , Issue.4 , pp. 372-379
    • Kaye, S.B.1    Lubinski, J.2    Matulonis, U.3
  • 24
    • 81155139687 scopus 로고    scopus 로고
    • A high response rate to liposo-mal doxorubicin is seen among women with BRCA mutations treated for recurrent epithelial ovarian cancer
    • Adams S F, Marsh EB, Elmasri W, et al. A high response rate to liposo-mal doxorubicin is seen among women with BRCA mutations treated for recurrent epithelial ovarian cancer. Gynecol Oncol. 2011;123(3):486-491.
    • (2011) Gynecol Oncol. , vol.123 , Issue.3 , pp. 486-491
    • Adams, S.F.1    Marsh, E.B.2    Elmasri, W.3
  • 25
    • 84873079682 scopus 로고    scopus 로고
    • Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: An open-label, single-arm, phase 2 study
    • Farley J, Brady WE, Vathipadiekal V, et al. Selumetinib in women with recurrent low-grade serous carcinoma of the ovary or peritoneum: an open-label, single-arm, phase 2 study. Lancet Oncol. 2013;14(2):134-140
    • (2013) Lancet Oncol. , vol.14 , Issue.2 , pp. 134-140
    • Farley, J.1    Brady, W.E.2    Vathipadiekal, V.3
  • 27
    • 52649085237 scopus 로고    scopus 로고
    • Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome
    • Tothill RW, Tinker AV, George J, et al. Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome. Clin Cancer Res. 2008;14(16):5198-5208.
    • (2008) Clin Cancer Res. , vol.14 , Issue.16 , pp. 5198-5208
    • Tothill, R.W.1    Tinker, A.V.2    George, J.3
  • 28
    • 79954570471 scopus 로고    scopus 로고
    • IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer
    • Anglesio MS, George J, Kulbe H, et al. IL6-STAT3-HIF signaling and therapeutic response to the angiogenesis inhibitor sunitinib in ovarian clear cell cancer. Clin Cancer Res. 2011;17(8):2538-2548.
    • (2011) Clin Cancer Res. , vol.17 , Issue.8 , pp. 2538-2548
    • Anglesio, M.S.1    George, J.2    Kulbe, H.3
  • 29
    • 79959923767 scopus 로고    scopus 로고
    • Identification of novel therapeutic targets in microdissected clear cell ovarian cancers
    • Stany MP, Vathipadiekal V, Ozbun L, et al. Identification of novel therapeutic targets in microdissected clear cell ovarian cancers. PLoS One. 2011;6(7):e21121.
    • (2011) PLoS One. , vol.6 , Issue.7
    • Stany, M.P.1    Vathipadiekal, V.2    Ozbun, L.3
  • 30
    • 84872862768 scopus 로고    scopus 로고
    • Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas
    • Anglesio MS, Kommoss S, Tolcher MC, et al. Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas. J Pathol. 2013;229(1):111-120.
    • (2013) J Pathol. , vol.229 , Issue.1 , pp. 111-120
    • Anglesio, M.S.1    Kommoss, S.2    Tolcher, M.C.3
  • 31
    • 84895782404 scopus 로고    scopus 로고
    • The BEST trial (E2804): A randomized phase II study of VEGF, RAF kinase, and mTOR combination targeted therapy (CTT) with bevacizumab (bev), sorafenib (sor), and temsirolimus (tem) in advanced renal cell carcinoma (RCC)
    • McDermott DF, Manola J, Pins M, et al. The BEST trial (E2804): a randomized phase II study of VEGF, RAF kinase, and mTOR combination targeted therapy (CTT) with bevacizumab (bev), sorafenib (sor), and temsirolimus (tem) in advanced renal cell carcinoma (RCC). J Clin Oncol. 2013;31(Supp):345.
    • (2013) J Clin Oncol. , vol.31 , Issue.SUPPL. , pp. 345
    • McDermott, D.F.1    Manola, J.2    Pins, M.3
  • 32
    • 67650652432 scopus 로고    scopus 로고
    • I-SPY 2: An adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy
    • Barker AD, Sigman CC, Kelloff GJ, et al. I-SPY 2: an adaptive breast cancer trial design in the setting of neoadjuvant chemotherapy. Clin Pharmacol Ther. 2009;86(1):97-100.
    • (2009) Clin Pharmacol Ther. , vol.86 , Issue.1 , pp. 97-100
    • Barker, A.D.1    Sigman, C.C.2    Kelloff, G.J.3
  • 33
    • 70349671467 scopus 로고    scopus 로고
    • A comparison of phase II study strategies
    • Hunsberger S, Zhao Y, Simon R. A comparison of phase II study strategies. Clin Cancer Res. 2009;15(19):5950-5955.
    • (2009) Clin Cancer Res. , vol.15 , Issue.19 , pp. 5950-5955
    • Hunsberger, S.1    Zhao, Y.2    Simon, R.3
  • 34
    • 51749123391 scopus 로고    scopus 로고
    • Speeding up the evaluation of new agents in cancer
    • Parmar MK, Barthel FM, Sydes M, et al. Speeding up the evaluation of new agents in cancer. J Natl Cancer Inst. 2008;100(17):1204-1214.
    • (2008) J Natl Cancer Inst. , vol.100 , Issue.17 , pp. 1204-1214
    • Parmar, M.K.1    Barthel, F.M.2    Sydes, M.3
  • 35
    • 84866145248 scopus 로고    scopus 로고
    • Flexible trial design in practice-stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: A multi-arm multi-stage randomized controlled trial
    • Sydes MR, Parmar MK, Mason MD, et al. Flexible trial design in practice-stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial. Trials. 2012;13:168.
    • (2012) Trials. , vol.13 , pp. 168
    • Sydes, M.R.1    Parmar, M.K.2    Mason, M.D.3
  • 36
    • 0030054309 scopus 로고    scopus 로고
    • Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer
    • McGuire III W P, Hoskins WJ, Brady MF, et al. Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancer. N Engl J Med. 1996;334(1):1-6.
    • (1996) N Engl J Med. , vol.334 , Issue.1 , pp. 1-6
    • McGuire III, W.P.1    Hoskins, W.J.2    Brady, M.F.3
  • 37
    • 0033986363 scopus 로고    scopus 로고
    • Phase III randomized study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal stage III or IV ovarian cancer: A Gynecologic Oncology Group study
    • Muggia FM, Braly PS, Brady MF, et al. Phase III randomized study of cisplatin versus paclitaxel versus cisplatin and paclitaxel in patients with suboptimal stage III or IV ovarian cancer: a Gynecologic Oncology Group study. J Clin Oncol. 2000;18(1):106-115.
    • (2000) J Clin Oncol. , vol.18 , Issue.1 , pp. 106-115
    • Muggia, F.M.1    Braly, P.S.2    Brady, M.F.3
  • 38
    • 84885092663 scopus 로고    scopus 로고
    • Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial muta-tional profiling
    • Bashashati A, Ha G, Tone A, et al. Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial muta-tional profiling. J Pathol. 2013;231(1):21-34.
    • (2013) J Pathol. , vol.231 , Issue.1 , pp. 21-34
    • Bashashati, A.1    Ha, G.2    Tone, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.