Association between performance on timed up and go subtasks and mild cognitive impairment: Further insights into the links between cognitive and motor function

Journal of the American Geriatrics Society

Volumn 62, Issue 4, 2014, Pages 673-678

  Mirelman, Anat ^a,b   Weiss, Aner ^a   Buchman, Aron S ^c   Bennett, David A ^c   Giladi, Nir ^a,d   Hausdorff, Jefferey M ^a,d,e  

^a TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^b BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^c RUSH UNIVERSITY MEDICAL CENTER   (United States)

^d TEL AVIV UNIVERSITY   (Israel)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

accelerometer; aging; cognition; gait; mild cognitive impairment

Indexed keywords

AGED; ARTICLE; COGNITION; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DEMENTIA; DISEASE COURSE; EDUCATIONAL STATUS; FEMALE; GAIT; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; MILD COGNITIVE IMPAIRMENT; MOTOR PERFORMANCE; NEUROLOGIC EXAMINATION; VELOCITY;

ACCELEROMETER; AGING; COGNITION; GAIT; MILD COGNITIVE IMPAIRMENT;

AGED, 80 AND OVER; AGING; COGNITION; CROSS-SECTIONAL STUDIES; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; GAIT DISORDERS, NEUROLOGIC; HUMANS; MALE; MILD COGNITIVE IMPAIRMENT; MOTOR ACTIVITY; PHYSICAL THERAPY MODALITIES; POSTURAL BALANCE; RETROSPECTIVE STUDIES; TIME FACTORS;

EID: 84898796018     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.12734     Document Type: Article

References (28)

1. Buchman AS, Boyle PA, Wilson RS, et al. Physical activity and motor decline in older persons. Muscle Nerve 2007; 35: 354-362.
2. Verghese J, Lipton RB, Hall CB, et al. Abnormality of gait as a predictor of non-Alzheimer's dementia. N Engl J Med 2002; 347: 1761-1768.
3. Hausdorff JM, Buchman AS,. What links gait speed and MCI with dementia? A fresh look at the association between motor and cognitive function. J Gerontol A Biol Sci Med Sci 2013; 68A: 409-411.
4. Buracchio T, Dodge HH, Howieson D, et al. The trajectory of gait speed preceding mild cognitive impairment. Arch Neurol 2010; 67: 980-986.
5. Waite LM, Grayson DA, Piguet O, et al. Gait slowing as a predictor of incident dementia: 6-year longitudinal data from the Sydney Older Persons Study. J Neurol Sci 2005; 229-230: 89-93.
6. Verghese J, Wang C, Lipton RB, et al. Motoric cognitive risk syndrome and the risk of dementia. J Gerontol A Biol Sci Med Sci 2013; 68A: 412-418.
7. Podsiadlo D, Richardson S,. The timed "Up & Go": A test of basic functional mobility for frail elderly persons. J Am Geriatr Soc 1991; 39: 142-148.
8. Hatch J, Gill-Body KM, Portney LG,. Determinants of balance confidence in community-dwelling elderly people. Phys Ther 2003; 83: 1072-1079.
9. Shumway-Cook A, Brauer S, Woollacott M,. Predicting the probability for falls in community-dwelling older adults using the "Timed Up & Go" test. Phys Ther 2000; 80: 896-903.
10. Guideline for the prevention of falls in older persons. American Geriatrics Society, British Geriatrics Society, and American Academy of Orthopaedic Surgeons Panel on Falls Prevention. J Am Geriatr Soc 2001; 49: 664-672.
11. Donoghue OA, Horgan NF, Savva GM, et al. Association between Timed Up and Go and memory, executive function, and processing speed. J Am Geriatr Soc 2012; 60: 1681-1686.
12. Herman T, Giladi N, Hausdorff JM,. Properties of the 'Timed Up and Go' test: More than meets the eye. Gerontology 2011; 57: 203-210.
13. Odonkor CA, Thomas JC, Holt N, et al. A comparison of straight- and curved-path walking tests among mobility-limited older adults. J Gerontol A Biol Sci Med Sci 2013; 68A: 1532-1539.
14. Weiss A, Mirelman A, Buchman AS, et al. Using a body-fixed sensor to identify subclinical gait difficulties in older adults with IADL disability: Maximizing the output of the Timed Up and Go. PLoS One 2013; 8: e68885.
15. Najafi B, Aminian K, Loew F, et al. Measurement of stand-sit and sit-stand transitions using a miniature gyroscope and its application in fall risk evaluation in the elderly. IEEE Trans Biomed Eng 2002; 49: 843-851.
16. Zijlstra W, Bisseling RW, Schlumbohm S, et al. A body-fixed-sensor-based analysis of power during sit-to-stand movements. Gait Posture 2010; 31: 272-278.
17. Weiss A, Herman T, Plotnik M, et al. An instrumented timed up and go: The added value of an accelerometer for identifying fall risk in idiopathic fallers. Physiol Meas 2011; 32: 2003-2018.
18. Salarian A, Zampieri C, Horak FB, et al. Analyzing 180 degrees turns using an inertial system reveals early signs of progression of Parkinson's disease. Conf Proc IEEE Eng Med Biol Soc 2009; 2009: 224-227.
19. Greene BR, McGrath D, Foran TG, et al. Body-worn sensor based surrogates of minimum ground clearance in elderly fallers and controls. Conf Proc IEEE Eng Med Biol Soc 2011; 2011: 6499-6502.
20. Bennett DA, Schneider JA, Buchman AS, et al. The Rush Memory and Aging Project: Study design and baseline characteristics of the study cohort. Neuroepidemiology 2005; 25: 163-175.
21. Weiss A, Herman T, Plotnik M, et al. Can an accelerometer enhance the utility of the "Timed Up and Go" test when evaluating patients with Parkinson's disease? Med Eng Phys 2010; 32: 119-125.
22. Benjamini Y, Hochberg Y,. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J Royal Stat Soc 1995; 57: 125-133.
23. Eggermont LH, Gavett BE, Volkers KM, et al. Lower-extremity function in cognitively healthy aging, mild cognitive impairment, and Alzheimer's disease. Arch Phys Med Rehabil 2010; 91: 584-588.
24. Holtzer R, Wang C, Lipton R, et al. The protective effects of executive functions and episodic memory on gait speed decline in aging defined in the context of cognitive reserve. J Am Geriatr Soc 2012; 60: 2093-2098.
25. Janssen WG, Bussmann HB, Stam HJ,. Determinants of the sit-to-stand movement: A review. Phys Ther 2002; 82: 866-879.
26. Buchman AS, Boyle PA, Leurgans SE, et al. Cognitive function is associated with the development of mobility impairments in community-dwelling elders. Am J Geriatr Psychiatry 2011; 19: 571-580.
27. Lord S, Galna B, Verghese J, et al. Independent domains of gait in older adults and associated motor and nonmotor attributes: Validation of a factor analysis approach. J Gerontol A Biol Sci Med Sci 2013; 68A: 820-827.
28. Salthouse TA,. The processing-speed theory of adult age differences in cognition. Psychol Rev 1996; 103: 403-428.