Inhibition of major virulence pathways of Streptococcus mutans by Quercitrin and Deoxynojirimycin: A synergistic approach of infection control

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Hasan, Sadaf ^a   Singh, Kunal ^b   Danisuddin, Mohd ^a   Verma, Praveen K ^b   Khan, Asad U ^a  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b NATIONAL INSTITUTE OF PLANT GENOME RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXYNOJIRIMYCIN; ADENOSINE TRIPHOSPHATASE; BACTERIAL ANTIGEN; BACTERIAL POLYSACCHARIDE; ENOLASE; F1F0 ADENOSINE TRIPHOSPHATASE; GLUCAN; LACTATE DEHYDROGENASE; QUERCITRIN; SPA P PROTEIN; SURFACE PROTEIN ANTIGEN I; SURFACE PROTEIN ANTIGEN II; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; DEOXYNOJIRIMYCINE; GLUCOSAMINE; QUERCETIN;

ARTICLE; BACTERIAL GENE; BACTERIAL GROWTH; BACTERIAL VIABILITY; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; BIOFILM; BRPA GENE; COMDE GENE; CONTROLLED STUDY; COVR GENE; DOWN REGULATION; DRUG POTENTIATION; GBPB GENE; GENE EXPRESSION; GTFC GENE; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; NONHUMAN; RELA GENE; SMU630 GENE; SPAP GENE; STREPTOCOCCUS MUTANS; VICR GENE; ANALOGS AND DERIVATIVES; CHEMICAL PHENOMENA; DRUG EFFECTS; EXTRACELLULAR SPACE; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; INFECTION CONTROL; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; PATHOGENICITY; PHYSIOLOGICAL STRESS; VIRULENCE;

1-DEOXYNOJIRIMYCIN; ANTI-BACTERIAL AGENTS; ANTIGENS, BACTERIAL; BACTERIAL ADHESION; BIOFILMS; DRUG SYNERGISM; EXTRACELLULAR SPACE; GENE EXPRESSION REGULATION, BACTERIAL; GLUCANS; GLUCOSAMINE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; INFECTION CONTROL; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; POLYSACCHARIDES, BACTERIAL; QUERCETIN; STREPTOCOCCUS MUTANS; STRESS, PHYSIOLOGICAL; VIRULENCE;

EID: 84898729748     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091736     Document Type: Article

References (47)

1. Hasan S, Danishuddin M, Adil M, Singh K, Verma PK, et al. (2012) Efficacy of E. officinalis on the Cariogenic Properties of Streptococcus mutans: A Novel and Alternative Approach to Suppress Quorum-Sensing Mechanissm. PLoS One 7: e40319.
2. Lévesque CM, Voronejskaia E, Huang YC, Mair RW, Ellen RP, et al. (2005) Involvement of sortase anchoring of cell wall proteins in biofilm formation by Streptococcus mutans. Infect Immun 73: 3773-7. (Pubitemid 40745925)
3. Miller-Torbert TA, Sharma S, Holt RG. (2008) Inactivation of a gene for a fibronectin-binding protein of the oral bacterium Streptococcus mutans partially impairs its adherence to fibronectin. Microb Pathog 45: 53-9.
4. Nakano K, Nomura R, Nemoto H, Mukai T, Yoshioka H, et al. (2007) Detection of novel serotype k Streptococcus mutans in infective endocarditis patients. J Med Microbiol56: 1413-5. (Pubitemid 350105615)
5. Quivey RG Jr, Kuhnert WL, Hahn K. (2000) Adaptation of oral streptococci to low pH. Adv Microb Physiol 42:239-74. (Pubitemid 30465953)
6. Schilling KM, Bowen WH. (1992) Glucans synthesized in situ in experimental salivary pellicle function as specific binding sites for Streptococcus mutans. Infect Immun 60:284-95.
7. Jeon JG, Rosalen PL, Falsetta ML, Koo H. (2011) Natural products in caries research: Current (limited) knowledge, challenges and future perspective. Caries Res 45: 243-263.
8. Kobayashi H, Suzuki T, Unemoto T. (1986) Streptococcal cytoplasmic pH is regulated by changes in amount and activity of a proton-translocating ATPase. J Biol Chem 261:627-30. (Pubitemid 16161716)
9. Xu X, Zhou XD, Wu CD. (2011) The tea catechin epigallocatechin gallate suppresses cariogenic virulence factors of Streptococcus mutans. Antimicrob Agents Chemother 55:1229-36.
10. Chen A, Hillman JD, Duncan M. (1994) L-(+)-lactate dehydrogenase deficiency is lethal in Streptococcus mutans. J Bacteriol 176:1542-1545. (Pubitemid 24080079)
11. Yamashita Y, Bowen WH, Burne RA, Kuramitsu HK. (1993) Role of the Streptococcus mutans gtf genes in caries induction in the specific-pathogen-free rat model. Infect Immun 61:3811-7. (Pubitemid 23260054)
12. Islam B, Khan SN, Haque I, Alam M, Mushfiq M.(2008) Novel antiadherence activity of Mulberry Leaves: Inhibition of Streptococcus mutans Bio-film by 1-Deoxynojirimycin isolated from Morus alba. J Antimicrob Chemother 62: 751-757.
13. Service RF (1995). Antibiotics that resist resistance. Science 270:724-7.
14. Hasan S, Ali SZ, Khan AU. (2013) Novel combinations of antibiotics to inhibit extended-spectrum β-lactamase and metallo-β-lactamase producers in vitro : a synergistic approach. Future Microbiol 8:939-44.
15. Müller P, Alber DG, Turnbull L, Schlothauer RC, Carter DA, et al. (2013) Synergism between Medihoney and rifampicin against methicillin-resistant Staphylococcus aureus (MRSA). PLoS One 8:e57679.
16. Celenza G, Segatore B, Setacci D, Bellio P, Brisdelli F, et al. (2012) In vitro antimicrobial activity of pannarin alone and in combination with antibiotics against methicillin-resistant Staphylococcus aureus clinical isolates. Phytomedicine 19:596-602.
17. Muzitano MF, Cruz EA, de Almeida AP, Da Silva SA, Kaiser CR, et al. (2006) Quercitrin: an antileishmanial flavonoid glycoside from Kalanchoe pinnata. Planta Med 72: 81-3. (Pubitemid 43241600)
18. Comalada M, Camuesco D, Sierra S, Ballester I, Xaus J, et al. (2005) In vivo quercitrin anti-inflammatory effect involves release of quercetin, which inhibits inflammation through down-regulation of the NF-kappaB pathway. Eur J Immuno35:584-92. (Pubitemid 40331335)
19. Muzitano MF, Cruz EA, de Almeida AP, Da Silva SA, Kaiser CR, et al. (2006) Quercitrin: an antileishmanial flavonoid glycoside from Kalanchoe pinnata. Planta Med 72: 81-3. (Pubitemid 43241600)
20. Hong CO, Lee HA, Rhee CH, Choung SY, Lee KW. (2013) Separation of the antioxidant compound quercitrin from Lindera obtusiloba Blume and its antimelanogenic effect on B16F10 melanomacells. Biosci Biotechnol Biochem 77: 58-64.
21. Wagner C, Fachinetto R, Dalla Corte CL, Brito VB, Severo D, et al. (2006) Quercitrin, a glycoside form of quercetin, prevents lipid peroxidation in vitro. Brain Res 30: 192-8. (Pubitemid 44205111)
22. Yin Y, Li W, Son YO, Sun L, Lu J, et al. (2013) Quercitrin protects skin from UVB-induced oxidative damage. Toxicol Appl Pharmacol 269: 89-99.
23. Tsuduki T, Kikuchi I, Kimura T, Nakagawa K, Miyazawa T. (2013) Intake of mulberry 1-deoxynojirimycin prevents diet-induced obesity through increases in adiponectin in mice. Food Chem 139:16-23.
24. Timokhova AV, Bakinovskiľ LV, Zinin AI, Popenko VI, Ivanov AV, et al. (2012) Affect of deoxynojirimycin derivatives on hepatitis C virus morphogenesis. Mol Biol (Mosk) 46:644-53.
25. Li YG, Ji DF, Zhong S, Lv ZQ, Lin TB. (2013) Cooperative anti-diabetic effects of deoxynojirimycin-polysaccharide by inhibiting glucose absorption and modulating glucose metabolism in streptozotocin-induced diabetic mice. PLoS One 8: e65892.
26. Ban SH, Kim JE, Pandit S, Jeon JG. (2012) Influences of Dryopteris crassirhizoma extract on the viability, growth and virulence properties of Streptococcus mutans. Molecules 17:9231-44.
27. Belli WA, Buckley DH, Marquis RE. (1995) Weak acid effects and fluoride inhibition of glycolysis by Streptococcus mutans GS-5. Can J Microbiol41:785-91.
28. Bencini DA, Shanley MS, Wild JR, O'Donovan GA. (1983) New assay for enzymatic phosphate release: Application to aspartate transcarbamylase and other enzymes. Ana Biochem132: 259-264.
29. Bradford MM. (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-54.
30. Crow VL, Pritchard GG. (1977). Fructose 1, 6-diphosphate-activated L-lactate dehydrogenase from Streptococcus lactis : kinetic properties and factors affecting activation. J. Bacteriol. 131:82-91. (Pubitemid 8153463)
31. Koo H, Gomes BP, Rosalen PL, Ambrosano GM, Park YK, Cury JA. (2000) In vitro antimicrobial activity of propolis and Arnica montana against oral pathogens. Arch Oral Biol 45: 141-148. (Pubitemid 30097337)
32. Dubois M, Gilles KA, Hamilton JK, Rebers PA, Smith F (1956). Colorimetric method for determination of sugars and related substance. Anal Chem 28: 350-356.
33. Hamada S, Torii M. (1978) Effect of sucrose in culture media on the location of glucosyltransferase of Streptococcus mutans and cell adherence to glass surfaces. Infect Immun 20: 592-599. (Pubitemid 8351991)
34. Loo CY, Corliss DA, Ganeshkumar N.(2000) Streptococcus gordonii biofim formation: identification of genes that code for biofilm phenotypes. J Bacteriol182: 1374-82. (Pubitemid 30104417)
35. Laurie AT, Jackson RM.(2005) Q-SiteFinder: an energy-based method for the prediction of protein-ligand binding sites. Bioinformatics 21:1908-16. (Pubitemid 40668026)
36. Jones G, Willett P, Glen RC. (1995) Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation. J Mol Biol 245: 43-53.
37. Kuramitsu HK.(1993) Virulence factors of mutans streptococci: role of molecular genetics. Crit Rev Oral Biol Med 4:159-76.
38. Gregoire S, Singh AP, Vorsa N, Koo H. (2007)Influence of cranberry phenolics on glucan synthesis by glucosyltransferases and Streptococcus mutans acidogenicity. J Appl Microbiol 103: 1960-1968. (Pubitemid 47620589)
39. Hamilton IR, Buckley ND. (1991) Adaptation by Streptococcus mutans to acid tolerance. Oral Microbiol Immunol 6: 65-71.
40. Lemos JA, Abranches J, Burne RA. (2005) Responses of cariogenic streptococci to environmental stresses. Curr Issues Mol Biol 7:95-107.
41. Postma PW, Lengeler JW, Jacobson GR. (1993) Phosphoenolpyruvate: carbohydrate phosphotransferase systems of bacteria. Microbiol Rev 57:543-94.
42. Yamashita Y, Bowen WH, Burne RA, Kuramitsu HK. (1993) Role of the Streptococcus mutans gtf genes in caries induction in the specific pathogen free rat model. Infect Immun 61: 3811-7. (Pubitemid 23260054)
43. McBride BC, Song M, Krasse B, Olsson J. (1994) Biochemical and immunological differences between hydrophobic and hydrophilic strain of Streptococcus mutans. Infect Immun 44: 68-75.
44. Wen ZT, Burne RA. (2002) Functional genomics approach to identifying genes required for biofilm development by Streptococcus mutans. Appl Environ Microbiol 68: 1196-203. (Pubitemid 34205358)
45. Larson MR, Rajashankar KR, Crowley PJ, Kelly C, Mitchell TJ. (2011) Crystal structure of the C-terminal region of Streptococcus mutans antigen I/II and characterization of salivary agglutinin adherence domains. J Biol Chem 286:21657-66.
46. Liu C, Worthington RJ, Melander C, Wu H. (2011) A new small molecule specifically inhibits the cariogenic bacterium Streptococcus mutans in multispecies biofilms. Antimicrob Agents Chemother 55: 2679-87.
47. Stipp RN, Boisvert H, Smith DJ, Höfling JF, Duncan MJ. (2013) CovR and VicRK Regulate Cell Surface Biogenesis Genes Required for Biofilm Formation in Streptococcus mutans. PLoS One 8: e58271.