Conditioned reinforcement can be mediated by either outcome-specific or general affective representations

Frontiers in Integrative Neuroscience

Volumn 1, Issue NOV, 2007, Pages

  Burke, Kathryn A ^a   Franz, Theresa M ^a   Miller, Danielle N ^b   Schoenbaum, Geoffrey ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b Baltimore Polytechnic Institute   (United States)

Author keywords

Basolateral amygdala; Conditioned reinforcement; Orbitofrontal cortex; Pavlovian conditioning; Rat; Reinforcer devaluation; Transreinforcer blocking

Indexed keywords

EID: 84898685806     PISSN: 16625145     EISSN: None     Source Type: Journal    
DOI: 10.3389/neuro.07.002.2007     Document Type: Article

References (33)

1. Balleine, B. W., and Corbit, L. H. (2005). Double dissociation of nucleus accumbens core and shell on the general and outcome-specific forms of pavlovian-instrumental transfer. Soc. Neurosci. Abstr. 71.16.
2. Baxter, M. G., Parker, A., Lindner, C. C., Izquierdo, A. D., and Murray, E. A. (2000). Control of response selection by reinforcer value requires interaction of amygdala and orbitofrontal cortex. J. Neurosci. 20, 4311-4319.
3. Burke, K. A., Miller, D. N., Franz, T. M., and Schoebaum, G. (2007). Orbitofrontal cortex lesions abolish conditioned reinforcement mediated by a representation of the expected outcome. Paper presented at New York Academy of Sciences Conference, Linking Affect to Action: Critical Contributions of the Orbitofrontal Cortex.
4. Burns, L. H., Robbins, T. W., and Everitt, B. J. (1993). Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum, and medial perfrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of d-amphetamine. Behav. Brain Res. 55, 167-183.
5. Cador, M., Robbins, T. W., and Everitt, B. J. (1989). Involvement of the amygdala in stimulus-reward associations: interactions with the ventral striatum. Neuroscience 30, 77-86.
6. Corbit, L. H., and Balleine, B. W. (2005). Double dissociation of basolateral and central amygdala lesions on the general and outcome-specific forms of pavlovianinstrumental transfer. J. Neurosci. 25, 962-970.
7. Cousens, G. A., and Otto, T. (2003). Neural substrates of olfactory discrimination learning with auditory secondary reinforcement. I. Contributions of the basolateral amygdaloid complex and orbitofrontal cortex. Integr. Physiol. Behav. Sci. 38, 272-294.
8. de Borchgrave, R., Rawlins, J. N., Dickinson, A., and Balleine, B. W. (2002). Effects of cytotoxic nucleus accumbens lesions on instrumental conditioning in rats. Exp. Brain Res. 144, 50-68.
9. Everitt, B. J., and Robbins, T. W. (1992). Amygdala-ventral striatal interactions and reward-related processes. In The Amygdala: Neurological Aspects of Emotion, Memory, and Mental Dysfunction, J. P. Aggleton, ed. (Oxford, John Wiley and Sons), pp. 401-429.
10. Gallagher, M., McMahan, R. W., and Schoenbaum, G. (1999). Orbitofrontal cortex and representation of incentive value in associative learning. J. Neurosci. 19, 6610-6614.
11. Gottfried, J. A., O'Doherty, J., and Dolan, R. J. (2003). Encoding predictive reward value in human amygdala and orbitofrontal cortex. Science 301, 1104-1107.
12. Hall, J., Parkinson, J. A., Connor, T.M., Dickinson, A., and Everitt, B. J. (2001). Involvement of the central nucleus of the amygdala and nucleus accumbens core in mediating Pavlovian influences on instrumental behavior. Eur. J. Neurosci. 13, 1984-1992.
13. Hatfield, T., Han, J. S., Conley, M., Gallagher, M., and Holland, P. (1996). Neurotoxic lesions of basolateral, but not central, amygdala interfere with Pavlovian second-order conditioning and reinforcer devaluation effects. J. Neurosci. 16, 5256-5265.
14. Holland, P. C. (2004). Relations between Pavlovian-instrumental transfer and reinforcer devaluation. J. Exp. Psychol.: Anim. Behav. Process. 30, 104-117.
15. Holland, P. C., and Gallagher, M. (2003). Double dissociation of the effects of lesions of basolateral and central amygdala on conditioned stimulus-potentiated feeding and Pavlovian-instrumental transfer. Eur. J. Neurosci. 17, 1680-1694.
16. Holland, P. C., and Rescorla, R. A. (1975). The effects of two ways of devaluing the unconditioned stimulus after first and second-order appetitive conditioning. J. Exp. Psychol.: Anim. Behav. Process. 1, 355-363.
17. Izquierdo, A. D., Suda, R. K., and Murray, E. A. (2004). Bilateral orbital prefrontal cortex lesions in rhesus monkeys disrupt choices guided by both reward value and reward contingency. J. Neurosci. 24, 7540-7548.
18. Malkova, L., Gaffan, D., and Murray, E. A. (1997). Excitotoxic lesions of the amygdala fail to produce impairment in visual learning for auditory secondary reinforcement but interfere with reinforcer devaluation effects in rhesus monkeys. J. Neurosci. 17, 6011-6020.
19. Ostlund, S. B., and Balleine, B.W. (2007). Orbitofrontal cortex mediates outcome encoding in Pavlovian but not instrumental learning. J. Neurosci. 27, 4819-4825.
20. Parkinson, J. A., Crofts, H. S., McGuigan, M., Tomic, D. L., Everitt, B. J., and Roberts, A. C. (2001). The role of the primate amygdala in conditioned reinforcement. J. Neurosci. 21, 7770-7780.
21. Parkinson, J. A., Olmstead, M. C., Burns, L. H., Robbins, T. W., and Everitt, B. J. (1999). Dissociation of effects of lesions of the nucleus accumbens core and shell on appetitive Pavlovian approach behavior and the potentiation of conditioned reinforcement and locomotor activity by d-amphetamine. J. Neurosci. 19, 2401-2411.
22. Parkinson, J. A., Roberts, A. C., Everitt, B. J., and Di Ciano, P. (2005). Acquisition of instrumental conditioned reinforcement is resistant to the devaluation of the unconditioned stimulus. Q. J. Exp. Psychol. 58, 19-30.
23. Pears, A., Parkinson, J. A., Hopewell, L., Everitt, B. J., and Roberts, A. C. (2003). Lesions of the orbitofrontal but not medial prefrontal cortex disrupt conditioned reinforcement in primates. J. Neurosci. 23, 11189-11201.
24. Pickens, C. L., Saddoris, M. P., Gallagher, M., and Holland, P. C. (2005). Orbitofrontal lesions impair use of cue-outcome associations in a devaluation task. Behav. Neurosci. 119, 317-322.
25. Pickens, C. L., Setlow, B., Saddoris, M. P., Gallagher, M., Holland, P. C., and Schoenbaum, G. (2003). Different roles for orbitofrontal cortex and basolateral amygdala in a reinforcer devaluation task. J. Neurosci. 23, 11078-11084.
26. Rescorla, R. A. (1999). Learning about qualitatively different outcomes during a blocking procedure. Anim. Learn. Behav. 27, 140-151.
27. Robledo, P., Robbins, T. W., and Everitt, B. J. (1996). Effects of excitotoxic lesions of hte central amygdaloid nucleus on the potentiation of reward-related stimuli by intra-accumbens amphetamine. Behav. Neurosci. 110, 981-990.
28. Schoenbaum, G., and Setlow, B. (2005). Cocaine makes actions insensitive to outcomes but not extinction: implications for altered orbitofrontal-amygdalar function. Cereb. Cortex 15, 1162-1169.
29. Schoenbaum, G., Setlow, B., Saddoris, M. P., and Gallagher, M. (2003). Encoding predicted outcome and acquired value in orbitofrontal cortex during cue sampling depends upon input from basolateral amygdala. Neuron 39, 855-867.
30. Setlow, B., Gallagher, M., and Holland, P. (2002a). The basolateral complex of the amygdala is necessary for acquisition but not expression of CS motivational value in appetitive Pavlovian second-order conditioning. Eur. J. Neurosci. 15, 1841-1853.
31. Setlow, B., Holland, P. C., and Gallagher, M. (2002b). Disconnection of the basolateral amygdala complex and nucleus accumbens impairs appetitive Pavlovian secondorder conditioned responses. Behav. Neurosci. 116, 267-275.
32. Taylor, J. R., and Robbins, T. W. (1984). Enhanced behavioral control by conditioned reinforcers following microinjections of d-amphetamine into the nucleus accumbens. Psychopharmacology 84, 405-412.
33. Whitelaw, R. B., Markou, A., Robbins, T. W., and Everitt, B. J. (1996). Excitotoxic lesions of the basolateral amygdala impair the acquisition of cocaine-seeking behaviour under a second-order schedule of reinforcement. Psychopharmacology (Berl.) 127, 213-224.