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Volumn 9, Issue 3, 2014, Pages

Gene silencing of SOCS3 by siRNA intranasal delivery inhibits asthma phenotype in mice

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; JANUS KINASE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; STAT PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; COLLAGEN; CYTOKINE; MICRORNA; SOCS3 PROTEIN, MOUSE; SUPPRESSOR OF CYTOKINE SIGNALING;

EID: 84898669702     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0091996     Document Type: Article
Times cited : (38)

References (34)
  • 1
    • 84860655039 scopus 로고    scopus 로고
    • Innate and adaptative immune responses in asthma
    • Holgate ST (2012) Innate and adaptative immune responses in asthma. Nat Med 18(5):673-83.
    • (2012) Nat Med , vol.18 , Issue.5 , pp. 673-683
    • Holgate, S.T.1
  • 3
    • 34249660614 scopus 로고    scopus 로고
    • SOCS proteins, cytokine signalling and immune regulation
    • DOI 10.1038/nri2093, PII NRI2093
    • Yoshimura A, Naka T, Kubo M (2007) SOCS proteins, cytokine signaling and immune regulation. Nat Rev Immunol 7(6):454-65. (Pubitemid 46834848)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.6 , pp. 454-465
    • Yoshimura, A.1    Naka, T.2    Kubo, M.3
  • 6
    • 51349169485 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 1 inhibits IFN-gamma inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation
    • Madonna S, Scarponi C, De Pita O, Albanesi C (2008) Suppressor of cytokine signaling 1 inhibits IFN-gamma inflammatory signaling in human keratinocytes by sustaining ERK1/2 activation. FASEB J 22:3287-3297.
    • (2008) FASEB J , vol.22 , pp. 3287-3297
    • Madonna, S.1    Scarponi, C.2    De Pita, O.3    Albanesi, C.4
  • 9
    • 1542359152 scopus 로고    scopus 로고
    • Differential expression of mRNA for Th1 and Th2 cytokine-associated transcription factors and suppressors of cytokine signalling in peripheral blood mononuclear cells of patients with atopic dermatitis
    • DOI 10.1111/j.1365-2249.2004.02405.x
    • 2 cytokine-associated transcription factors and suppressors of cytokine signaling in peripheral blood mononuclear cells of patients with atopic dermatitis. Clin Exp Immunol 135:505-510. (Pubitemid 38297154)
    • (2004) Clinical and Experimental Immunology , vol.135 , Issue.3 , pp. 505-510
    • Arakawa, S.1    Hatano, Y.2    Katagiri, K.3
  • 10
    • 33646113393 scopus 로고    scopus 로고
    • Overexpression of the suppressor of cytokine signaling 3 (SOCS3) in severe atopic dermatitis
    • Horiuchi Y, Bae SJ, Katayama I (2006) Overexpression of the suppressor of cytokine signaling 3 (SOCS3) in severe atopic dermatitis. Clin Exp Dermatol 31:100-104.
    • (2006) Clin Exp Dermatol , vol.31 , pp. 100-104
    • Horiuchi, Y.1    Bae, S.J.2    Katayama, I.3
  • 11
    • 79953747618 scopus 로고    scopus 로고
    • T cell treatment with small interfering RNA for suppressor of cytokine signaling 3 modulates allergic airway responses in a murine model of asthma
    • Moriwaki A, Inoue H, Nakano T, Matsunaga Y, Matsuno Y, et al. (2011) T cell treatment with small interfering RNA for suppressor of cytokine signaling 3 modulates allergic airway responses in a murine model of asthma. Am J Respir Cell Mol Biol 44(4):448-55.
    • (2011) Am J Respir Cell Mol Biol , vol.44 , Issue.4 , pp. 448-455
    • Moriwaki, A.1    Inoue, H.2    Nakano, T.3    Matsunaga, Y.4    Matsuno, Y.5
  • 12
    • 13444262170 scopus 로고    scopus 로고
    • Inhibition of respiratory viruses by nasally administered siRNA
    • DOI 10.1038/nm1164
    • Bitko V, Musiyenko A, Shulyayeva O, Barik S (2005) Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 11(1):50-5. (Pubitemid 40215837)
    • (2005) Nature Medicine , vol.11 , Issue.1 , pp. 50-55
    • Bitko, V.1    Musiyenko, A.2    Shulyayeva, O.3    Barik, S.4
  • 13
    • 77249102130 scopus 로고    scopus 로고
    • Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis
    • Bonifazi P, D'Angelo C, Zagarella S, Zelante T, Bozza S, et al. (2010) Intranasally delivered siRNA targeting PI3K/Akt/mTOR inflammatory pathways protects from aspergillosis. Mucosal Immunol 3(2):193-205.
    • (2010) Mucosal Immunol , vol.3 , Issue.2 , pp. 193-205
    • Bonifazi, P.1    D'Angelo, C.2    Zagarella, S.3    Zelante, T.4    Bozza, S.5
  • 14
    • 82855167217 scopus 로고    scopus 로고
    • Intraairway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuated allergic asthma in mice
    • Miyamoto S, Hattori N, Senoo T, Onari Y, Iwamoto H, et al. (2011) Intraairway administration of small interfering RNA targeting plasminogen activator inhibitor-1 attenuated allergic asthma in mice. Am J Physiol Lung Cell Mol Physiol 301:L908-L916.
    • (2011) Am J Physiol Lung Cell Mol Physiol , vol.301
    • Miyamoto, S.1    Hattori, N.2    Senoo, T.3    Onari, Y.4    Iwamoto, H.5
  • 15
    • 0030800586 scopus 로고    scopus 로고
    • Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography
    • Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, et al. (1997) Noninvasive measurement of airway responsiveness in allergic mice using barometric plethysmography. Am J Respir Crit Care Med 156:766-755.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 766-755
    • Hamelmann, E.1    Schwarze, J.2    Takeda, K.3    Oshiba, A.4    Larsen, G.L.5
  • 16
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schimittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 22DDCT method. Methods 25:402-408. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 18
    • 84883158559 scopus 로고    scopus 로고
    • An IL-4/IL-13 dual antagonist reduces lung inflammation, airway hyperresponsiveness, and IgE production in mice
    • Kasaian MT, Marquette K, Fish S, De Clercq C, Agostinelly R, et al. (2013) An IL-4/IL-13 dual antagonist reduces lung inflammation, airway hyperresponsiveness, and IgE production in mice. Am J Respir Cell Mol Biol 49(1):37-46.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , Issue.1 , pp. 37-46
    • Kasaian, M.T.1    Marquette, K.2    Fish, S.3    De Clercq, C.4    Agostinelly, R.5
  • 19
    • 80053475355 scopus 로고    scopus 로고
    • Role of Rho kinase isoforms in murine allergic airway responses
    • Zhu M, Liu P, Kasahara DI, Williams AS, Verbout NG, et al. (2011) Role of Rho kinase isoforms in murine allergic airway responses. Eur Respire J 38(4):841-850.
    • (2011) Eur Respire J , vol.38 , Issue.4 , pp. 841-850
    • Zhu, M.1    Liu, P.2    Kasahara, D.I.3    Williams, A.S.4    Verbout, N.G.5
  • 20
    • 70350125752 scopus 로고    scopus 로고
    • Rho kinase (ROCK) inhibitors and their application to inflammatory disorders
    • Lo Grasso PV, Feng Y (2009) Rho kinase (ROCK) inhibitors and their application to inflammatory disorders. Curr Top Med Chem 9(8):704-23.
    • (2009) Curr Top Med Chem , vol.9 , Issue.8 , pp. 704-723
    • Lo Grasso, P.V.1    Feng, Y.2
  • 21
    • 73949147807 scopus 로고    scopus 로고
    • Interleukin-4 upregulates RhoA protein via an activation of STAT6 in cultured human bronchial smooth muscle cells
    • Chiba Y, Todokori M, Misawa M (2010) Interleukin-4 upregulates RhoA protein via an activation of STAT6 in cultured human bronchial smooth muscle cells. Pharmacol Res 61(2):188-92.
    • (2010) Pharmacol Res , vol.61 , Issue.2 , pp. 188-192
    • Chiba, Y.1    Todokori, M.2    Misawa, M.3
  • 22
    • 59149107299 scopus 로고    scopus 로고
    • Interleukin-13 augments bronchial smooth muscle contractility with an upregulation of RhoA protein
    • Chiba Y, Nakazawa S, Todokori M, Shinozaki K, Sakai H, et al. (2009) Interleukin-13 augments bronchial smooth muscle contractility with an upregulation of RhoA protein. Am J Respir Cell Mol Biol 40:159-67.
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 159-167
    • Chiba, Y.1    Nakazawa, S.2    Todokori, M.3    Shinozaki, K.4    Sakai, H.5
  • 23
    • 78649424607 scopus 로고    scopus 로고
    • RhoA, a possible target for treatment of airway hyperresponsiveness in bronchial asthma
    • Chiba Y, Matsusue K, Misawa M (2010) RhoA, a possible target for treatment of airway hyperresponsiveness in bronchial asthma. J Pharmacol Sci 114(3):239-47.
    • (2010) J Pharmacol Sci , vol.114 , Issue.3 , pp. 239-247
    • Chiba, Y.1    Matsusue, K.2    Misawa, M.3
  • 24
    • 77950629897 scopus 로고    scopus 로고
    • The proximal STAT6 and NF-kB sites are responsible for IL-13 and TNF-a-induced RhoA transcriptions in human bronchial smooth cells
    • Goto K, Chiba Y, Matsusue K, Hattori Y, Maitani Y, et al. (2010) The proximal STAT6 and NF-kB sites are responsible for IL-13 and TNF-a-induced RhoA transcriptions in human bronchial smooth cells. Pharmacol Res 61(5):466-72.
    • (2010) Pharmacol Res , vol.61 , Issue.5 , pp. 466-472
    • Goto, K.1    Chiba, Y.2    Matsusue, K.3    Hattori, Y.4    Maitani, Y.5
  • 27
    • 33645849231 scopus 로고    scopus 로고
    • Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-b1
    • Kinjyo I, Inoue H, Hamano S, Fukuyama S, Yoshimura T, et al. (2006) Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-b1. JEM 203(4):1021-31.
    • (2006) JEM , vol.203 , Issue.4 , pp. 1021-1031
    • Kinjyo, I.1    Inoue, H.2    Hamano, S.3    Fukuyama, S.4    Yoshimura, T.5
  • 28
    • 78650341401 scopus 로고    scopus 로고
    • Induction of tolerogenic lung CD4+ T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthma
    • Hausding M, Tepe M, Ubel C, Lehr HA, Röhrig B, et al. (2010) Induction of tolerogenic lung CD4+ T cells by local treatment with a pSTAT-3 and pSTAT-5 inhibitor ameliorated experimental allergic asthma. Int Immunol 23(1):1-15.
    • (2010) Int Immunol , vol.23 , Issue.1 , pp. 1-15
    • Hausding, M.1    Tepe, M.2    Ubel, C.3    Lehr, H.A.4    Röhrig, B.5
  • 29
    • 13444262170 scopus 로고    scopus 로고
    • Inhibition of respiratory viruses by nasally administered siRNA
    • DOI 10.1038/nm1164
    • Bitko V, Musiyenko A, Shulyayeva O, Barik S (2005) Inhibition of respiratory viruses by nasally administered siRNA. Nat Med 11(1):50-5. (Pubitemid 40215837)
    • (2005) Nature Medicine , vol.11 , Issue.1 , pp. 50-55
    • Bitko, V.1    Musiyenko, A.2    Shulyayeva, O.3    Barik, S.4
  • 30
    • 24744466699 scopus 로고    scopus 로고
    • Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque
    • Li BJ, Quingquan T, Cheng D, Qin C, Xie FY, et al. (2005) Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med 11(9):441-51.
    • (2005) Nat Med , vol.11 , Issue.9 , pp. 441-451
    • Li, B.J.1    Quingquan, T.2    Cheng, D.3    Qin, C.4    Xie, F.Y.5
  • 31
    • 77952688315 scopus 로고    scopus 로고
    • A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncitial virus
    • De Vincenzo J, Lambkin-Williams R, Wilkinson T, Cehelsky J, Nochur S, et al. (2010) A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncitial virus. PNAS 107(19):8800-05.
    • (2010) PNAS , vol.107 , Issue.19 , pp. 8800-8805
    • De Vincenzo, J.1    Lambkin-Williams, R.2    Wilkinson, T.3    Cehelsky, J.4    Nochur, S.5
  • 32
    • 79956193631 scopus 로고    scopus 로고
    • Altered expression of microRNA in the airway wall in chronic asthma: MiR-126 as a potential therapeutic target
    • doi:10.1186/1471-2466-11-29
    • Collison A, Herbert C, Siegle JS, Mattes J, Foster PS, et al. (2011) Altered expression of microRNA in the airway wall in chronic asthma: miR-126 as a potential therapeutic target. BMC Pul Med doi:10.1186/1471-2466-11-29.
    • (2011) BMC Pul Med
    • Collison, A.1    Herbert, C.2    Siegle, J.S.3    Mattes, J.4    Foster, P.S.5
  • 33
    • 79551565924 scopus 로고    scopus 로고
    • MicroRNAs profiling in murine models of acute and chronic asthma: A relationship with mRNAs targets
    • doi:10.1371/journal.pone.0016509
    • Garbacki N, Di Valentin E, Huynh-Thu VA, Geurts P, Irrthum A, et al. (2011) MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets. PLoS One doi:10.1371/journal.pone.0016509.
    • (2011) PLoS One
    • Garbacki, N.1    Di Valentin, E.2    Huynh-Thu, V.A.3    Geurts, P.4    Irrthum, A.5
  • 34
    • 66749152769 scopus 로고    scopus 로고
    • Noninvasive quantitative tomography of the therapeutic response to dexamethasone in ovalbumin-induced murine asthma
    • Korideck H, Peterson JD (2009) Noninvasive quantitative tomography of the therapeutic response to dexamethasone in ovalbumin-induced murine asthma. JPET 329:882-89.
    • (2009) JPET , vol.329 , pp. 882-889
    • Korideck, H.1    Peterson, J.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.