Selection of an aptamer against rabies virus: A new class of molecules with antiviral activity

Virus Research

Volumn 184, Issue , 2014, Pages 7-13

  Liang, Hong Ru ^a,b   Hu, Gui Qiu ^b   Xue, Xiang Hong ^b   Li, Lu ^b   Zheng, Xue Xing ^b   Gao, Yu Wei ^b   Yang, Song Tao ^b   Xia, Xian Zhu ^b  

^a SOUTH CHINA SEA FISHERIES RESEARCH INSTITUTE   (China)

^b BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Aptamer; Rabies virus; Therapeutic agents

Indexed keywords

ANTIVIRUS AGENT; APTAMER; GE 54; GE 58; GT 1; GT 3; GTE 33; SINGLE STRANDED DNA; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIVIRAL ACTIVITY; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFICACY; FELINE PANLEUKOPENIA VIRUS; HAMSTER; IN VITRO STUDY; IN VIVO STUDY; INTRACRANIAL DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABIES; RABIES VIRUS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VERO CELL; ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMOPROPHYLAXIS; COMBINATORIAL CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; FEMALE; ISOLATION AND PURIFICATION; PHYSIOLOGY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; SURVIVAL; VIRUS LOAD; VIRUS REPLICATION;

ANIMALS; ANTIVIRAL AGENTS; APTAMERS, NUCLEOTIDE; CELL LINE; CHEMOPREVENTION; CRICETINAE; DISEASE MODELS, ANIMAL; FEMALE; MICE, INBRED BALB C; RABIES; RABIES VIRUS; REAL-TIME POLYMERASE CHAIN REACTION; SELEX APTAMER TECHNIQUE; SURVIVAL ANALYSIS; VIRAL LOAD; VIRUS REPLICATION;

EID: 84898665546     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2014.01.021     Document Type: Article

References (14)

1. Albertini A.A., Schoehn G., Weissenhorn W., Ruigrok R.W. Structural aspects of rabies virus replication. Cell. Mol. Life Sci. 2008, 65(2):282-294.
2. Allendorf S.D., et al. Rabies virus distribution in tissues and molecular characterization of strains from naturally infected non-hematophagous bats. Virus Res. 2012, 165(2):119-125.
3. Chen C.H., et al. Aptamer-based endocytosis of a lysosomal enzyme. Proc. Natl. Acad. Sci. U.S.A. 2008, 105(41):15908-15913.
4. Farokhzad O.C., et al. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl. Acad. Sci. U.S.A. 2006, 103(16):6315-6320.
5. Kunii T., Ogura S., Mie M., Kobatake E. Selection of DNA aptamers recognizing small cell lung cancer using living cell-SELEX. Analyst 2011, 136(7):1310-1312.
6. Liang H.-R., et al. Aptamers targeting rabies virus-infected cells inhibit viral replication both in vitro and in vivo. Virus Res. 2013, 173(2):398-403.
7. Liang H.R., et al. Isolation of ssDNA aptamers that inhibit rabies virus. Int. Immunopharmacol. 2012.
8. Masatani T., et al. Amino acids at positions 273 and 394 in rabies virus nucleoprotein are important for both evasion of host RIG-I-mediated antiviral response and pathogenicity. Virus Res. 2011, 155(1):168-174.
9. Roy A., Hooper D.C. Immune evasion by rabies viruses through the maintenance of blood-brain barrier integrity. J. Neurovirol. 2008, 14(5):401-411.
10. Yadav D.K., Ashraf S., Singh P.K., Tuli R. Localization of rabies virus glycoprotein into the endoplasmic reticulum produces immunoprotective antigen. Protein J. 2012, 31(6):447-456.
11. Yamada K., et al. Serial passage of a street rabies virus in mouse neuroblastoma cells resulted in attenuation: potential role of the additional N-glycosylation of a viral glycoprotein in the reduced pathogenicity of street rabies virus. Virus Res. 2012, 165(1):34-45.
12. Zhang K., et al. A novel aptamer developed for breast cancer cell internalization. ChemMedChem 2012, 7(1):79-84.
13. Zhang W., et al. An adenovirus-delivered peptide aptamer C1-1 targeting the core protein of hepatitis B virus inhibits viral DNA replication and production in vitro and in vivo. Peptides 2009, 30(10):1816-1821.
14. Zhou J., Rossi J.J. Aptamer-targeted cell-specific RNA interference. Silence 2010, 1(1):4.