Antisense piRNA amplification, but not piRNA production or nuage assembly, requires the Tudor-domain protein Qin

EMBO Journal

Volumn 33, Issue 6, 2014, Pages 536-539

  Zhang, Zhao ^a   Koppetsch, Birgit S ^a   Wang, Jie ^a   Tipping, Cindy ^a   Weng, Zhiping ^a   Theurkauf, William E ^a   Zamore, Phillip D ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; PIWI INTERACTING RNA;

ALLELE; CHROMOSOME; DIPTERA; FEMALE; GENE; LETTER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; QIN GENE; RNA SEQUENCE; TRANSPOSON;

ANIMALS; DROSOPHILA PROTEINS; FEMALE; GERM CELLS; RNA, SMALL INTERFERING;

EID: 84898656910     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1002/embj.201384895     Document Type: Letter

References (3)

1. Anand A, Kai T, (2012) The tudor domain protein kumo is required to assemble the nuage and to generate germline piRNAs in Drosophila. EMBO J 31: 870-882
2. Brennecke J, Aravin AA, Stark A, Dus M, Kellis M, Sachidanandam R, Hannon GJ, (2007) Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila. Cell 128: 1089-1103 (Pubitemid 46427877)
3. Zhang Z, Xu J, Koppetsch BS, Wang J, Tipping C, Ma S, Weng Z, Theurkauf WE, Zamore PD, (2011) Heterotypic piRNA ping-pong requires Qin, a protein with both E3-ligase and tudor domains. Mol Cell 44: 572-584