L-Arginine stimulates fibroblast proliferation through the GPRC6A-ERK1/2 and PI3K/Akt pathway

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Fujiwara, Takashi ^a   Kanazawa, Shigeyuki ^a   Ichibori, Ryoko ^a   Tanigawa, Tomoko ^a   Magome, Takuya ^b   Shingaki, Kenta ^c   Miyata, Shingo ^d   Tohyama, Masaya ^d   Hosokawa, Ko ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c Department of Research and Development Noevir Co Ltd ^*  (Japan)

^d KINKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR FAMILY C GROUP 6 SUBTYPE A; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; GPRC6A PROTEIN, HUMAN; MITOGEN ACTIVATED PROTEIN KINASE 3;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; 3T3 CELL LINE; ANIMAL; ANTAGONISTS AND INHIBITORS; CYTOLOGY; DERMIS; DRUG EFFECTS; ENZYMOLOGY; GENE SILENCING; METABOLISM; MOUSE;

ANIMALS; APOPTOSIS; ARGININE; CELL PROLIFERATION; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DERMIS; ENZYME ACTIVATION; FIBROBLASTS; GENE KNOCKDOWN TECHNIQUES; HUMANS; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NIH 3T3 CELLS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84898656217     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0092168     Document Type: Article

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