The tendon injury response is influenced by decorin and biglycan

Annals of Biomedical Engineering

Volumn 42, Issue 3, 2014, Pages 619-630

  Dunkman, Andrew A ^a   Buckley, Mark R ^a   Mienaltowski, Michael J ^b   Adams, Sheila M ^b   Thomas, Stephen J ^a   Satchell, Lauren ^a   Kumar, Akash ^a   Pathmanathan, Lydia ^a   Beason, David P ^a   Iozzo, Renato V ^c   Birk, David E ^b   Soslowsky, Louis J ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Biglycan; Decorin; Extracellular matrix; Healing; Injury; Proteogly can; SLRP; Tendon

Indexed keywords

GENE EXPRESSION; GLYCOPROTEINS; MAMMALS; MECHANICAL PROPERTIES; MECHANICAL TESTING; POLYMERASE CHAIN REACTION;

BIGLYCAN; DECORIN; EXTRACELLULAR MATRICES; HEALING; INJURY; PROTEOGLY-CAN; SLRP;

TENDONS;

BIGLYCAN; COLLAGEN; DECORIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL SHAPE; CONTROLLED STUDY; FEMALE; FIBER; FRACTURE HEALING; GENE EXPRESSION; HEALING IMPAIRMENT; MOUSE; NONHUMAN; PATELLA TENDON; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TENDON INJURY; WILD TYPE;

ANIMALS; BIGLYCAN; COLLAGEN; DECORIN; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; MICE; MICE, KNOCKOUT; PATELLAR LIGAMENT; TENDON INJURIES;

EID: 84898639375     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-013-0915-2     Document Type: Article

References (30)

1. Ameye, L., D. Aria, K. Jepsen, A. Oldberg, T. Xu, and M. F. Young. Abnormal collagen fibrils in tendons of bigly-can/fibromodulin-deficient mice lead to gait impairment, ectopic ossification, and osteoarthritis. FASEB J. 6:673-680, 2002.
2. Ansorge, H. L., S. Adams, D. E. Birk, and L. J. Soslowsky. Mechanical, compositional, and structural properties of the post-natal mouse Achilles tendon. Ann. Biomed. Eng. 39:1904-1913, 2011.
3. Ansorge, H. L., S. Adams, A. F. Jawad, D. E. Birk, and L. J. Soslowsky. Mechanical property changes during neonatal development and healing using a multiple regression model. J. Biomech. 45:1288-1292, 2012.
4. Berglund, M., C. Reno, D. A. Hart, and M. Wiig. Patterns of mRNA expression for matrix molecules and growth factors in flexor tendon injury: differences in the regulation between tendon and tendon sheath. J. Hand Surg. Am. 31:1279-1287, 2006.
5. Birk, D. E., and P. Bruckner. Collagen suprastructures. In: Topics in Current Chemistry: Collagen, edited by J. Brinckmann, P. K. Muller, and H. Notbohm. Berlin: Springer-Verlag, 247:185-205, 2005.
6. Birk, D. E., M. V. Nurminskaya, and E. I. Zycband. Collagen fibrillogenesis in situ: fibril segments undergo post-depositional modifications resulting in linear and lateral growth during matrix development. Dev. Dyn. 202:229-243, 1995.
7. Buckley, M. R., A. A. Dunkman, K. E. Reuther, A. Kumar, L. Pathmanathan, D. P. Beason, D. E. Birk, and L. J. Soslowsky. Validation of an empirical damage model for aging and in vivo injury of the murine patellar tendon. J. Biomech. Eng. 135:041005-1-7.
8. Chen, S., and D. E. Birk. 2013 The regulatory roles of small leucine-rich proteoglycans in extracellular assembly. FEBS J. 2013: 10.1111/febs.12136.
9. Connizzo, B. K., J. J. Sarver, D. E. Birk, and L. J. Soslowsky. Effect of age and proteoglycan deficiency on collagen fiber re-alignment and mechanical properties in mouse supraspinatus tendon. J. Biomech. Eng. 135(2): 021019, 2013.
10. Corsi, A., T. Xu, X. D. Chen, A. Boyde, J. Liang, M. Mankani, B. Sommer, R. V. Iozzo, I. Eichstetter, P. G. Robey, P. Bianco, and M. F. Young. Phenotypic effects of biglycan deficiency are linked to collagen fibril abnormalities, are synergized by decorin deficiency, and mimic Ehlers-Danlos-like changes in bone and other connective tissues. J. Bone Miner. Res. 17:1180-1189, 2002.
11. Dafforn, A., P. Chen, G. Deng, M. Herrler, D. Iglehart, S. Koritala, S. Lato, S. Pillarisetty, R. Purohit, M. Wang, S. Wang, and N. Kurn. Linear mRNA amplification from as little as 5 ng total RNA for global gene expression analysis. Biotechniques 37:854-857, 2004.
12. Dourte, L. M., L. Pathmanathan, A. F. Jawad, R. V. Iozzo, M. J. Mienaltowski, D. E. Birk, and L. J. Soslowsky. Influence of decorin on the mechanical, compositional, and structural properties of the mouse patellar tendon. J. Bio-mech. 134(3):031005, 2012.
13. Dunkman, A. A., M. R. Buckley, M. J. Mienaltowski, A. Kumar, D. P. Beason, L. Pathmanathan, L. D. E. Birk, and L. J. Soslowsky. 2013. Dynamic mechanical properties of tendon repair tissue are unaffected by aging. Trans. Orthop. Res. Soc. 38:614.
14. Dunkman, A. A., M. R. Buckley, M. J. Mienaltowski, S. M. Adams, S. J. Thomas, L. Satchell, A. Kumar, L. Pathmanathan, D. P. Beason, R. V. Iozzo, D. E. Birk, and L. J. Soslowsky. Decorin expression is required for age-related changes in tendon structure and mechanical properties. Matrix Biol. 32:3-13, 2013.
15. Ezura, Y., S. Chakravarti, A. Oldberg, I. Chervoneva, and D. E. Birk. Differential expression of lumican and fibro-modulin regulate collagen fibrillogenesis in developing mouse tendons. J. Cell Biol. 151:779-788, 2000.
16. Favata, M. Scarless healing in the fetus: Implications and strategies for postnatal tendon repair. Dissertation available from ProQuest. Paper AAI3246156, 2006.
17. Iozzo, R. V. The biology of the small leucine-rich proteo-glycans. Functional network of interactive proteins. J. Biol. Chem. 274:18843-18846, 1999.
18. Kumar, A., A. A. Dunkman, M. R. Buckley, L. Pathmanathan, M. J. Mienaltowski, D. P. Beason, R. V. Iozzo, D. E. Birk, and L. J. Soslowsky. Tendon repair response to injury is affected by the absence of biglycan and decorin. Trans. Orthop. Res. Soc. 37:158, 2012.s
19. Leadbetter, W. B. Cell-matrix response in tendon injury. Clin. Sports Med. 11:533-578, 1992.
20. Lin, T. W., L. Cardenas, D. L. Glaser, and L. J. Soslowsky. Tendon healing in interleukin-4 and interleukin-6 knockout mice. J. Biomech. 39:61-69, 2006.
21. Lui, P. P., Y. C. Cheuk, Y. W. Lee, and K. M. Chan. Ectopic chondro-ossification and erroneous extracellular matrix deposition in a tendon window injury model. J. Orthop. Res. 301:37-46, 2012.
22. Lujan, T. J., C. J. Underwood, N. T. Jacobs, and J. A. Weiss. Contribution of glycosaminoglycans to viscoelastic tensile behavior of human ligament. J. Appl. Physiol. 106:423-431, 2009.
23. Ramakers, C., J. M. Ruijter, R. H. Deprez, and A. F. Moorman. Assumption-free analysis of quantitative realtime polymerase chain reaction (PCR) data. Neurosci. Lett. 339, 62-66, 2003.
24. Reed, C. C., and R. V. Iozzo. The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconj. J. 19:249-255, 2002.
25. Ruhland, C., E. Schonherr, H. Robenek, U. Hansen, R. V. Iozzo, P. Bruckner, and D. G. Seidler. The glycosamino-glycan chain of decorin plays an important role in collagen fibril formation at the early stages of fibrillogenesis. FEBS J. 274:4246-4255, 2007.
26. Schefe, J. H., K. E. Lehmann, I. R. Buschmann, T. Unger, and H. Funke-Kaiser. Quantitative real-time RT-PCR data analysis: current concepts and the novel "gene expression's CT difference" formula. J. Mol. Med. 84:901-910, 2006.
27. Young, M. F., Y. Bi, L. Ameye, and X. D. Chen. Biglycan knockout mice: new models for musculoskeletal diseases. Glycoconj. J. 19:257-262, 2002.
28. Zhang, G., S. Chen, S. Goldoni, B. W. Calder, H. C. Simpson, R. T. Owens, D. J. McQuillan, M. F. Young, R. V. Iozzo, and D. E. Birk. Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan. J. Biol. Chem. 284:8888-8897, 2009.
29. Zhang, G., Y. Ezura, I. Chervoneva, P. S. Robinson, D. P. Beason, E. T. Carine, L. J. Soslowsky, R. V. Iozzo, and D. E. Birk. Decorin regulates assembly of collagen fibrils and acquisition of biomechanical properties during tendon development. J. Cell. Biochem. 98:1436-1449, 2006.
30. Zhang, G., B. B. Young, Y. Ezura, M. Favata, L. J. Soslowsky, S. Chakravarti, and D. E. Birk. Development of tendon structure and function: regulation of collagen fibrillogenesis. J. Musculoskeletal. Neuronal. Interact. 5:5-21, 2005.