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Volumn 54, Issue 4, 2014, Pages 375-377

Vemurafenib oral bioavailability: An insoluble problem

Author keywords

bioavailability; food effect; melanoma; pharmacokinetics; Vemurafenib

Indexed keywords

VEMURAFENIB;

EID: 84898626787     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1002/jcph.277     Document Type: Review
Times cited : (5)

References (10)
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  • 4
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    • Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process
    • Shah N, Iyer RM, Mair HJ, et al. Improved human bioavailability of vemurafenib, a practically insoluble drug, using an amorphous polymer-stabilized solid dispersion prepared by a solvent-controlled coprecipitation process. J Pharm Sci. 2013; 102 (3): 967-981.
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  • 5
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    • Food and Drug Administration, Center for Drug Evaluation and Research. Application number: 202429Orig1s000. Clinical Pharmacology and Biopharmaceutics Review(s)
    • Accessed February 11, 2014.
    • Food and Drug Administration, Center for Drug Evaluation and Research. Application number: 202429Orig1s000. Clinical Pharmacology and Biopharmaceutics Review(s). Zelboraf. http://www.accessdata.fda.gov/drugsatfda-docs/nda/2011/ 202429Orig1s000ClinPharmR.pdf. Accessed February 11, 2014.
    • Zelboraf
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    • Playing Russian roulette with tyrosine kinase inhibitors
    • Szmulewitz RZ, Ratain MJ,. Playing Russian roulette with tyrosine kinase inhibitors. Clin Pharmacol Ther. 2013; 93 (3): 242-244.
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  • 9
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    • Inhibition of mutated, activated BRAF in metastatic melanoma
    • Flaherty KT, Puzanov I, Kim KB, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010; 363 (9): 809-819.
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.