Learning from errors: Response to Gefitinib in kidney urothelial carcinoma with EGFR mutations

Oncologist

Volumn 19, Issue 4, 2014, Pages 430-

  Fiorentino, Michelangelo ^a   Giunchi, Francesca ^a   Altimari, Annalisa ^a   Di Tullio, Piergiorgio ^b   Gruppioni, Elisa ^a   Martorana, Giuseppe ^b   Pinto, Carmine ^b  

^a F Addarii Institute of Oncology   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOPLATIN; EPIDERMAL GROWTH FACTOR RECEPTOR; GEFITINIB; GEMCITABINE; ANTINEOPLASTIC AGENT; DEOXYCYTIDINE; EGFR PROTEIN, HUMAN; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE;

ABDOMINAL PAIN; ADULT; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DRUG WITHDRAWAL; EGFR GENE; FEMALE; FOLLOW UP; GENE; GENE MUTATION; HEMATURIA; HUMAN; HUMAN TISSUE; KIDNEY CARCINOMA; KIDNEY METASTASIS; LUNG BIOPSY; LUNG CANCER; LUNG LESION; MIDDLE AGED; NEPHRECTOMY; NOTE; PRIORITY JOURNAL; SMOKING; TRANSBRONCHIAL BIOPSY; TRANSITIONAL CELL CARCINOMA; ANALOGS AND DERIVATIVES; CARCINOMA, SQUAMOUS CELL; GENETICS; KIDNEY; KIDNEY NEOPLASMS; LUNG NEOPLASMS; MUTATION; PATHOLOGY; SECONDARY; UROTHELIUM;

ANTINEOPLASTIC AGENTS; CARBOPLATIN; CARCINOMA, SQUAMOUS CELL; DEOXYCYTIDINE; FEMALE; HUMANS; KIDNEY; KIDNEY NEOPLASMS; LUNG NEOPLASMS; MIDDLE AGED; MUTATION; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; UROTHELIUM;

EID: 84898493183     PISSN: 10837159     EISSN: 1549490X     Source Type: Journal    
DOI: 10.1634/theoncologist.2013-0346     Document Type: Note

References (3)

1. Blehm KN, Spiess PE, Bondaruk JE et al. Mutations within the kinase domain and truncations of the epidermal growth factor receptor are rare events in bladder cancer: Implications for therapy. Clin Cancer Res 2006;12:4671-4677.
2. Chaux A, Cohen JS, Schultz L et al. High epidermal growth factor receptor immunohistochemical expression in urothelial carcinoma of the bladder is not associated with EGFR mutations in exons 19 and 21: A study using formalinfixed, paraffin-embedded archival tissues. Hum Pathol 2012;43:1590-1595.
3. Jiang SX, Yamashita K, Yamamoto M et al. EGFR genetic heterogeneity of nonsmall cell lung cancers contributing to acquired gefitinib resistance. Int J Cancer 2008;123:2480-2486.