Albumin replacement in patients with severe sepsis or septic shock

New England Journal of Medicine

Volumn 370, Issue 15, 2014, Pages 1412-1421

  Caironi, Pietro ^a,b   Tognoni, Gianni ^f   Masson, Serge ^c   Fumagalli, Roberto ^d   Pesenti, Antonio ^d   Romero, Marilena ^f   Fanizza, Caterina ^f   Caspani, Luisa ^b   Faenza, Stefano ^g   Grasselli, Giacomo ^h   Iapichino, Gaetano ^a,e   Antonelli, Massimo ⁱ   Parrini, Vieri ^j   Fiore, Gilberto ^k   Latini, Roberto ^c   Gattinoni, Luciano ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b MAGGIORE HOSPITAL   (Italy)

^c MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^d UNIVERSITY OF MILANO BICOCCA   (Italy)

^e FATEBENEFRATELLI HOSPITAL   (Italy)

^f Santa Maria Imbaro   (Italy)

^g UNIVERSITY OF BOLOGNA   (Italy)

^h SAN GERARDO HOSPITAL   (Italy)

ⁱ FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^j SANTA MARIA ANNUNZIATA HOSPITAL   (Italy)

^k S CROCE E CARLE HOSPITAL   (Italy)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ARTICLE; CAUSE OF DEATH; CONTROLLED STUDY; CRYSTALLOID; FEMALE; FLUID BALANCE; HOSPITAL DISCHARGE; HUMAN; INTENSIVE CARE; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; MIDDLE AGED; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEPSIS; SEPTIC SHOCK; SUBSTITUTION THERAPY; TREATMENT RESPONSE;

AGED; ALBUMINS; FEMALE; HUMANS; ISOTONIC SOLUTIONS; MALE; MIDDLE AGED; REHYDRATION SOLUTIONS; SEPSIS; SERUM ALBUMIN; SHOCK, SEPTIC; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 84898487262     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1305727     Document Type: Article

References (27)

1. Erstad BL, Gales BJ, Rappaport WD. The use of albumin in clinical practice. Arch Intern Med 1991;151:901-11.
2. Cochrane Injuries Group Albumin Reviewers. Human albumin administration in critically ill patients: systematic review of randomised controlled trials. BMJ 1998;317:235-40.
3. Wilkes MM, Navickis RJ. Patient survival after human albumin administration: a meta-analysis of randomized, controlled trials. Ann Intern Med 2001;135:149-64. (Pubitemid 32738309)
4. Vincent JL, Dubois MJ, Navickis RJ, Wilkes MM. Hypoalbuminemia in acute illness: is there a rationale for intervention? A meta-analysis of cohort studies and controlled trials. Ann Surg 2003; 237:319-34. (Pubitemid 38176446)
5. Finfer S, Bellomo R, Boyce N, French J, Myburgh J, Norton R. A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 2004;350:2247-56. (Pubitemid 38669207)
6. Dubois MJ, Orellana-Jimenez C, Melot C, et al. Albumin administration improves organ function in critically ill hypoalbuminemic patients: a prospective, randomized, controlled, pilot study. Crit Care Med 2006;34:2536-40. (Pubitemid 44413049)
7. Quinlan GJ, Martin GS, Evans TW. Albumin: biochemical properties and therapeutic potential. Hepatology 2005;41: 1211-9. (Pubitemid 40770271)
8. Weil MH, Henning RJ, Puri VK. Colloid oncotic pressure: clinical significance. Crit Care Med 1979;7:113-6.
9. Sudlow G, Birkett DJ, Wade DN. The characterization of two specific drug binding sites on human serum albumin. Mol Pharmacol 1975;11:824-32.
10. King TP. On the sulfhydryl group of human plasma albumin. J Biol Chem 1961;236:PC5.
11. Quinlan GJ, Margarson MP, Mumby S, Evans TW, Gutteridge JM. Administration of albumin to patients with sepsis syndrome: a possible beneficial role in plasma thiol repletion. Clin Sci (Lond) 1998;95:459-65. (Pubitemid 28474732)
12. Stamler JS, Jaraki O, Osborne J, et al. Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin. Proc Natl Acad Sci U S A 1992;89:7674-7.
13. Reeves RB. Temperature-induced changes in blood acid-base status: Donnan rCl and red cell volume. J Appl Physiol 1976;40:762-7.
14. Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest 1992;101:1644-55.
15. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77.
16. Le Gall JR, Lemeshow S, Saulnier F. A new Simplified Acute Physiology Score (SAPS II) based on a European/North American multicenter study. JAMA 1993;270: 2957-63. [Erratum, JAMA 1994;271:1321.] (Pubitemid 24000804)
17. Vincent JL, Moreno R, Takala J, et al. The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. Intensive Care Med 1996;22:707-10. (Pubitemid 26254283)
18. Vincent JL, de Mendonça A, Cantraine F, et al. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Crit Care Med 1998;26:1793-800. (Pubitemid 28527688)
19. Moreno R, Vincent JL, Matos R, et al. The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care: results of a prospective, multicentre study. Working Group on Sepsis related Problems of the ESICM. Intensive Care Med 1999;25:686-96. (Pubitemid 29376122)
20. Kellum JA, Bellomo R, Ronco C. The concept of acute kidney injury and the RIFLE criteria. Contrib Nephrol 2007;156:10-6.
21. Vincent JL. Relevance of albumin in modern critical care medicine. Best Pract Res Clin Anaesthesiol 2009;23:183-91.
22. Vincent JL, Gottin L. Type of fluid in severe sepsis and septic shock. Minerva Anestesiol 2011;77:1190-6.
23. The SAFE Study Investigators. Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis. Intensive Care Med 2011;37:86-96.
24. Delaney AP, Dan A, McCaffrey J, Finfer S. The role of albumin as a resuscitation fluid for patients with sepsis: a systematic review and meta-analysis. Crit Care Med 2011;39:386-91.
25. Hollenberg SM, Piotrowski MJ, Parrillo JE. Nitric oxide synthase inhibition reverses arteriolar hyporesponsiveness to endothelin-1 in septic rats. Am J Physiol 1997;272:R969-R974.
26. Titheradge MA. Nitric oxide in septic shock. Biochim Biophys Acta 1999;1411: 437-55. (Pubitemid 29221966)
27. McCann KB, Vucica Y, Famulari S, Bertolini J. Effect of processing methods on colouration of human serum albumin preparations. Biologicals 2009;37:32-6.