-
1
-
-
84855564475
-
Nextgeneration sequencing for cancer diagnostics: A practical perspective
-
Meldrum C, Doyle MA, Tothill RW. Nextgeneration sequencing for cancer diagnostics: A practical perspective. Clin Biochem Rev 2011;32: 177-195.
-
(2011)
Clin Biochem Rev
, vol.32
, pp. 177-195
-
-
Meldrum, C.1
Doyle, M.A.2
Tothill, R.W.3
-
2
-
-
84874533657
-
Combining highly multiplexed PCR with semiconductorbased sequencing for rapid cancer genotyping
-
Beadling C, Neff TL, Heinrich MC et al. Combining highly multiplexed PCR with semiconductorbased sequencing for rapid cancer genotyping. JMol Diagn 2013;15:171-176.
-
(2013)
JMol Diagn
, vol.15
, pp. 171-176
-
-
Beadling, C.1
Neff, T.L.2
Heinrich, M.C.3
-
3
-
-
84882289495
-
Clinical validation of a next-generation sequencing screen formutational hotspots in 46 cancer-related genes
-
Singh RR, Patel KP, Routbort MJ et al. Clinical validation of a next-generation sequencing screen formutational hotspots in 46 cancer-related genes. J Mol Diagn 2013;15:607-622.
-
(2013)
J Mol Diagn
, vol.15
, pp. 607-622
-
-
Singh, R.R.1
Patel, K.P.2
Routbort, M.J.3
-
4
-
-
84878874062
-
Next-generation screening goes national in UK
-
Next-generation screening goes national in UK. Cancer Discov 2013;3:OF6.
-
(2013)
Cancer Discov
, vol.3
-
-
-
5
-
-
49649087385
-
Essential roles of PI(3)Kp110beta in cell growth, metabolism and tumorigenesis
-
Jia S, Liu Z, Zhang S et al. Essential roles of PI(3)Kp110beta in cell growth, metabolism and tumorigenesis. Nature 2008;454:776-779.
-
(2008)
Nature
, vol.454
, pp. 776-779
-
-
Jia, S.1
Liu, Z.2
Zhang, S.3
-
6
-
-
84874519595
-
Targeted, high-depth, next-generation sequencing of cancer genes in formalin-fixed, paraffinembedded and fine-needle aspiration tumor specimens
-
Hadd AG, Houghton J, Choudhary A et al. Targeted, high-depth, next-generation sequencing of cancer genes in formalin-fixed, paraffinembedded and fine-needle aspiration tumor specimens. J Mol Diagn 2013;15:234-247.
-
(2013)
J Mol Diagn
, vol.15
, pp. 234-247
-
-
Hadd, A.G.1
Houghton, J.2
Choudhary, A.3
-
7
-
-
84871325703
-
Mutation scanning using MUT-MAP, a high-throughput, microfluidic chip-based, multi-analyte panel
-
Patel R, Tsan A, Tam R et al. Mutation scanning using MUT-MAP, a high-throughput, microfluidic chip-based, multi-analyte panel. PLoS One 2012;7: e51153.
-
(2012)
PLoS One
, vol.7
-
-
Patel, R.1
Tsan, A.2
Tam, R.3
-
8
-
-
84872849091
-
Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention
-
Jia S, Gao X, Lee SH et al. Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention. Cancer Discov 2013;3: 44-51.
-
(2013)
Cancer Discov
, vol.3
, pp. 44-51
-
-
Jia, S.1
Gao, X.2
Lee, S.H.3
-
9
-
-
19444371824
-
A germline mutation in KIT in familial diffuse cutaneous mastocytosis
-
Tang X, Boxer M, Drummond A et al. A germline mutation in KIT in familial diffuse cutaneous mastocytosis. J Med Genet 2004;41:e88.
-
(2004)
J Med Genet
, vol.41
-
-
Tang, X.1
Boxer, M.2
Drummond, A.3
-
10
-
-
0034641890
-
A novel germ line juxtamembrane Met mutation in human gastric cancer
-
Lee JH, Han SU, Cho H et al. A novel germ line juxtamembrane Met mutation in human gastric cancer. Oncogene 2000;19:4947-4953.
-
(2000)
Oncogene
, vol.19
, pp. 4947-4953
-
-
Lee, J.H.1
Han, S.U.2
Cho, H.3
-
11
-
-
84863922124
-
Comprehensive molecular characterization of human colon and rectal cancer
-
Cancer Genome Atlas Network
-
Cancer Genome Atlas Network. Comprehensive molecular characterization of human colon and rectal cancer. Nature 2012;487:330-337.
-
(2012)
Nature
, vol.487
, pp. 330-337
-
-
-
12
-
-
36248962105
-
The genomic landscapes of human breast and colorectal cancers
-
Wood LD, Parsons DW, Jones S et al. The genomic landscapes of human breast and colorectal cancers. Science 2007;318:1108-1113.
-
(2007)
Science
, vol.318
, pp. 1108-1113
-
-
Wood, L.D.1
Parsons, D.W.2
Jones, S.3
-
13
-
-
84874650275
-
Development of PI3K inhibitors: Lessons learned from early clinical trials
-
Rodon J, Dienstmann R, Serra V et al. Development of PI3K inhibitors: Lessons learned from early clinical trials. Nat Rev Clin Oncol 2013;10: 143-153.
-
(2013)
Nat Rev Clin Oncol
, vol.10
, pp. 143-153
-
-
Rodon, J.1
Dienstmann, R.2
Serra, V.3
-
14
-
-
74749085995
-
Prospects for personalized medicine with inhibitors targeting the RAS and PI3K pathways
-
Lackner MR. Prospects for personalized medicine with inhibitors targeting the RAS and PI3K pathways. Expert Rev Mol Diagn 2010;10:75-87.
-
(2010)
Expert Rev Mol Diagn
, vol.10
, pp. 75-87
-
-
Lackner, M.R.1
-
15
-
-
63749106157
-
Should individual PI3 kinase isoformsbetargetedin cancer?
-
Jia S, Roberts TM, Zhao JJ. Should individual PI3 kinase isoformsbetargetedin cancer? Curr Opin Cell Biol 2009;21:199-208.
-
(2009)
Curr Opin Cell Biol
, vol.21
, pp. 199-208
-
-
Jia, S.1
Roberts, T.M.2
Zhao, J.J.3
-
16
-
-
52449092107
-
Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling
-
She QB, Chandarlapaty S, Ye Q et al. Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling. PLoS One 2008;3:e3065.
-
(2008)
PLoS One
, vol.e3065
, pp. 3
-
-
She, Q.B.1
Chandarlapaty, S.2
Ye, Q.3
-
17
-
-
84871254065
-
Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models
-
Spoerke JM, O'Brien C, Huw L et al. Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models. Clin Cancer Res 2012;18: 6771-6783.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 6771-6783
-
-
Spoerke, J.M.1
O'Brien, C.2
Huw, L.3
-
18
-
-
79959974471
-
Targeting PI3K signaling as a therapeutic approach for colorectal cancer
-
Zhang J, Roberts TM, Shivdasani RA. Targeting PI3K signaling as a therapeutic approach for colorectal cancer. Gastroenterology 2011;141:50-61.
-
(2011)
Gastroenterology
, vol.141
, pp. 50-61
-
-
Zhang, J.1
Roberts, T.M.2
Shivdasani, R.A.3
-
19
-
-
84865591846
-
A tale of three next generation sequencing platforms: Comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers
-
Quail MA, Smith M, Coupland P et al. A tale of three next generation sequencing platforms: Comparison of Ion Torrent, Pacific Biosciences and Illumina MiSeq sequencers. BMC Genomics 2012; 13:341.
-
(2012)
BMC Genomics
, vol.13
, pp. 341
-
-
Quail, M.A.1
Smith, M.2
Coupland, P.3
-
20
-
-
79952109738
-
Comparing the roles of the p110a and p110b isoforms of PI3K in signaling and cancer
-
Ilić N, Roberts TM. Comparing the roles of the p110a and p110b isoforms of PI3K in signaling and cancer. Curr Top Microbiol Immunol 2010;347: 55-77.
-
(2010)
Curr Top Microbiol Immunol
, vol.347
, pp. 55-77
-
-
Ilić, N.1
Roberts, T.M.2
-
21
-
-
0036843937
-
Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas
-
Kurose K, Gilley K, Matsumoto S et al. Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas. Nat Genet 2002;32: 355-357.
-
(2002)
Nat Genet
, vol.32
, pp. 355-357
-
-
Kurose, K.1
Gilley, K.2
Matsumoto, S.3
-
22
-
-
84865456673
-
Algorithm for codevelopment of new drug-predictive biomarker combinations: Accounting for inter- and intrapatient tumor heterogeneity
-
Gandara DR, Li T, Lara PN Jr. et al. Algorithm for codevelopment of new drug-predictive biomarker combinations: Accounting for inter- and intrapatient tumor heterogeneity. Clin Lung Cancer 2012; 13:321-325.
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 321-325
-
-
Gandara, D.R.1
Li, T.2
Lara Jr., P.N.3
-
24
-
-
84879823947
-
Targeted therapy: Tailoring cancer treatment
-
Yan M, Liu QQ. Targeted therapy: Tailoring cancer treatment. Chin J Cancer 2013;32:363-364.
-
(2013)
Chin J Cancer
, vol.32
, pp. 363-364
-
-
Yan, M.1
Liu, Q.Q.2
-
25
-
-
77953143235
-
Targeted cancer therapies
-
Aggarwal S. Targeted cancer therapies. NatRev Drug Discov 2010;9:427-428.
-
(2010)
NatRev Drug Discov
, vol.9
, pp. 427-428
-
-
Aggarwal, S.1
|