The association between statin medication and progression after surgery for localized renal cell carcinoma

Journal of Urology

Volumn 191, Issue 4, 2014, Pages 914-919

  Hamilton, Robert J ^a,d   Morilla, Daniel ^e   Cabrera, Fernando ^b   Leapman, Michael ^c   Chen, Ling Y ^a   Bernstein, Melanie ^a   Hakimi, A Ari ^a   Reuter, Victor E ^a   Russo, Paul ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b SUNY DOWNSTATE MEDICAL CENTER   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF TORONTO   (Canada)

^e TRIPLER ARMY MEDICAL CENTER   (United States)

Author keywords

chemoprevention; disease progression; hydroxymethylglutaryl CoA reductase inhibitors; kidney neoplasms; nephrectomy

Indexed keywords

ATORVASTATIN; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN;

ADULT; AGED; ARTICLE; CANCER GROWTH; CANCER LOCALIZATION; CANCER MORTALITY; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG USE; FEMALE; FOLLOW UP; HUMAN; KIDNEY CANCER; KIDNEY CARCINOMA; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; METASTASIS; OVERALL SURVIVAL; PARTIAL NEPHRECTOMY; PRIORITY JOURNAL; RISK REDUCTION; SENSITIVITY ANALYSIS; TREATMENT OUTCOME; CANCER RECURRENCE; COMORBIDITY; NEPHRECTOMY; RETROSPECTIVE STUDY;

CHEMOPREVENTION; DISEASE PROGRESSION; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KIDNEY NEOPLASMS; NEPHRECTOMY;

AGED; CARCINOMA, RENAL CELL; DISEASE PROGRESSION; FEMALE; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; KIDNEY NEOPLASMS; MALE; MIDDLE AGED;

EID: 84898436285     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2013.10.141     Document Type: Article

References (27)

1. P. Russo Multi-modal treatment for metastatic renal cancer: the role of surgery World J Urol 28 2010 295
2. P.E. Teloken, R.H. Thompson, and S.K. Tickoo et al. Prognostic impact of histological subtype on surgically treated localized renal cell carcinoma J Urol 182 2009 2132
3. L. Cindolo, J.J. Patard, and P. Chiodini et al. Comparison of predictive accuracy of four prognostic models for nonmetastatic renal cell carcinoma after nephrectomy: a multicenter European study Cancer 104 2005 1362
4. L.L. Bañez, J.C. Klink, and J. Jayachandran et al. Association between statins and prostate tumor inflammatory infiltrate in men undergoing radical prostatectomy Cancer Epidemiol Biomarkers Prev 19 2010 722
5. C. Wang, W. Tao, and Y. Wang et al. Rosuvastatin, identified from a zebrafish chemical genetic screen for antiangiogenic compounds, suppresses the growth of prostate cancer Eur Urol 58 2010 418
6. T. Nübel, W. Dippold, and H. Kleinert et al. Lovastatin inhibits Rho-regulated expression of E-selectin by TNFalpha and attenuates tumor cell adhesion FASEB J 18 2004 140
7. J. Wu, W.W. Wong, and F. Khosravi et al. Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis Cancer Res 64 2004 6461
8. J. Woodard, A. Sassano, and N. Hay et al. Statin-dependent suppression of the Akt/mammalian target of rapamycin signaling cascade and programmed cell death 4 up-regulation in renal cell carcinoma Clin Cancer Res 14 2008 4640
9. A. Horiguchi, M. Sumitomo, and J. Asakuma et al. 3-hydroxy-3- methylglutaryl-coenzyme A reductase inhibitor, fluvastatin, as a novel agent for prophylaxis of renal cancer metastasis Clin Cancer Res 10 2004 8648
10. V. Khurana, G. Caldito, and M. Ankem Statins might reduce risk of renal cell carcinoma in humans: case-control study of 500,000 veterans Urology 71 2008 118
11. W. Liu, T.K. Choueiri, and E. Cho Statin use and the risk of renal cell carcinoma in 2 prospective US cohorts Cancer 118 2012 797
12. H.F. Chiu, C.C. Kuo, and H.W. Kuo et al. Statin use and the risk of kidney cancer: a population-based case-control study Expert Opin Drug Saf 11 2012 543
13. T.C. Weng, Y.H. Yang, and S.J. Lin et al. A systematic review and meta-analysis on the therapeutic equivalence of statins J Clin Pharm Ther 35 2010 139
14. M.R. Graaf, A.B. Beiderbeck, and A.C. Egberts et al. The risk of cancer in users of statins J Clin Oncol 22 2004 2388
15. P.F. Coogan, L. Rosenberg, and B.L. Strom Statin use and the risk of 10 cancers Epidemiology 18 2007 213
16. J.A. Kaye, and H. Jick Statin use and cancer risk in the General Practice Research Database Br J Cancer 90 2004 635
17. G.D. Friedman, E.D. Flick, and N. Udaltsova et al. Screening statins for possible carcinogenic risk: up to 9 years of follow-up of 361,859 recipients Pharmacoepidemiol Drug Saf 17 2008 27
18. J. Bil, L. Zapala, and D. Nowis et al. Statins potentiate cytostatic/cytotoxic activity of sorafenib but not sunitinib against tumor cell lines in vitro Cancer Lett 288 2010 57
19. R. Gutt, N. Tonlaar, and R. Kunnavakkam et al. Statin use and risk of prostate cancer recurrence in men treated with radiation therapy J Clin Oncol 28 2010 2653
20. R.J. Hamilton, L.L. Banez, and W.J. Aronson et al. Statin medication use and the risk of biochemical recurrence after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) Database Cancer 116 2010 3389
21. T.P. Ahern, L. Pedersen, and M. Tarp et al. Statin prescriptions and breast cancer recurrence risk: a Danish nationwide prospective cohort study J Natl Cancer Inst 103 2011 1461
22. M.L. Kwan, L.A. Habel, and E.D. Flick et al. Post-diagnosis statin use and breast cancer recurrence in a prospective cohort study of early stage breast cancer survivors Breast Cancer Res Treat 109 2008 573
23. S.F. Nielsen, B.G. Nordestgaard, and S.E. Bojesen Statin use and reduced cancer-related mortality N Engl J Med 367 2012 1792
24. Cholesterol Treatment Trialists' (CTT) Collaboration C. Baigent, and L. Blackwell et al. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials Lancet 376 2010 1670
25. M.S. Katz, P.R. Carroll, and J.E. Cowan et al. Association of statin and nonsteroidal anti-inflammatory drug use with prostate cancer outcomes: results from CaPSURE BJU Int 106 2010 627
26. V. Misrai, C. Do, and J.M. Lhez et al. Is statin use associated with D'Amico risk groups and biochemical recurrence after radical prostatectomy? Prog Urol 22 2012 273
27. E.A. Platz, M.F. Leitzmann, and K. Visvanathan et al. Statin drugs and risk of advanced prostate cancer J Natl Cancer Inst 98 2006 1819