Stage-specific embryonic antigen 4 in wharton's jelly-derived mesenchymal stem cells is not a marker for proliferation and multipotency

Tissue Engineering - Part A

Volumn 20, Issue 7-8, 2014, Pages 1314-1324

  He, Haiping ^a,b   Nagamura Inoue, Tokiko ^a   Tsunoda, Hajime ^c   Yuzawa, Miki ^a   Yamamoto, Yuki ^a   Yorozu, Pariko ^a   Agata, Hideki ^a   Tojo, Arinobu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b First People's Hospital of Yunnan Province   (China)

^c Nippon Telegraph and Telephone Corporation Medical Center Tokyo   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGENS; FLOWCHARTING; POLYMERASE CHAIN REACTION; STEM CELLS;

CULTURE CONDITIONS; EMBRYONIC STEM CELLS; EXPRESSION PROFILE; FETAL BOVINE SERUM; LONG-TERM CULTURE; MESENCHYMAL STEM CELL; REVERSE TRANSCRIPTION-POLYMERASE CHAIN REACTION; UMBILICAL CORDS;

CELL CULTURE;

CELL MARKER; COLLAGENASE; STAGE SPECIFIC EMBRYO ANTIGEN 4; BIOLOGICAL MARKER; STAGE SPECIFIC EMBRYO ANTIGEN; STAGE-SPECIFIC EMBRYONIC ANTIGEN-3; STAGE-SPECIFIC EMBRYONIC ANTIGEN-4; TUMOR ANTIGEN;

ADIPOCYTE; ANTIGEN EXPRESSION; ARTICLE; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; EMBRYONIC STEM CELL; FLOW CYTOMETRY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; NUCLEOTIDE SEQUENCE; OSTEOCYTE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WHARTON JELLY; BONE DEVELOPMENT; BONE MARROW CELL; CYTOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; MULTIPOTENT STEM CELL; UMBILICAL CORD;

ADIPOCYTES; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; BIOLOGICAL MARKERS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL PROLIFERATION; FLOW CYTOMETRY; HUMANS; MESENCHYMAL STROMAL CELLS; MULTIPOTENT STEM CELLS; OSTEOGENESIS; STAGE-SPECIFIC EMBRYONIC ANTIGENS; UMBILICAL CORD; WHARTON JELLY;

EID: 84898435611     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2013.0333     Document Type: Article

References (24)

1. Ishige, I., Nagamura-Inoue, T., Honda, M.J., Harnprasopwat, R., Kido, M., Sugimoto, M., et al. Comparison of mesenchymal stem cells derived from arterial, venous, and Wharton's jelly explants of human umbilical cord. Int J Hematol 90, 261, 2009
2. Kode, J.A., Mukherjee, S., Joglekar, M.V., and Hardikar, A.A. Mesenchymal stem cells: Immunobiology and role in immunomodulation and tissue regeneration. Cytotherapy 11, 377, 2009
3. Zeddou, M., Briquet, A., Relic, B., Josse, C., Malaise, M.G., Gothot, A., et al. The umbilical cord matrix is a better source of mesenchymal stem cells (MSC) than the umbilical cord blood. Cell Biol Int 34, 693, 2010
4. Horwitz, E.M., Le Blanc, K., Dominici, M., Mueller, I., Slaper-Cortenbach, I., Marini, F.C., et al. Clarification of the nomenclature for MSC: The International Society for Cellular Therapy position statement. Cytotherapy 7, 393, 2005
5. Dominici, M., Le Blanc, K., Mueller, I., Slaper-Cortenbach, I., Marini, F., Krause, D., et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8, 315, 2006
6. Anzalone, R., Iacono, M.L., Corrao, S., Magno, F., Loria, T., Cappello, F., et al. New emerging potentials for human Wharton's jelly mesenchymal stem cells: Immunological features and hepatocyte-like differentiative capacity. Stem Cells Dev 19, 423, 2010
7. Carvalho, M.M., Teixeira, F.G., Reis, R.L., Sousa, N., and Salgado, A.J. Mesenchymal stem cells in the umbilical cord: Phenotypic characterization, secretome and applications in central nervous system regenerative medicine. Curr Stem Cell Res Ther 6, 221, 2011
8. Hsieh, J.Y., Fu, Y.S., Chang, S.J., Tsuang, Y.H., and Wang, H.W. Functional module analysis reveals differential osteogenic and stemness potentials in human mesenchymal stem cells from bone marrow and Wharton's jelly of umbilical cord. Stem Cells Dev 19, 1895, 2010
9. Fong, C.Y., Chak, L.L., Biswas, A., Tan, J.H., Gauthaman, K., Chan, W.K., et al. Human Wharton's jelly stem cells have unique transcriptome profiles compared to human embryonic stem cells and other mesenchymal stem cells. Stem Cell Rev 7, 1, 2011
10. Kannagi, R., Cochran, N.A., Ishigami, F., Hakomori, S., Andrews, P.W., Knowles, B.B., et al. Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside isolated from human teratocarcinoma cells. EMBO J 2, 2355, 1983
11. Gang, E.J., Bosnakovski, D., Figueiredo, C.A., Visser, J.W., and Perlingeiro, R.C. SSEA-4 identifies mesenchymal stem cells from bone marrow. Blood 109, 1743, 2007
12. Kuroda, Y., Kitada, M., Wakao, S., Nishikawa, K., Tanimura, Y., Makinoshima, H., et al. Unique multipotent cells in adult human mesenchymal cell populations. Proc Natl Acad Sci USA 107, 8639, 2010
13. Wakao, S., Kitada, M., Kuroda, Y., and Dezawa, M. Isolation of adult human pluripotent stem cells from mesenchymal cell populations and their application to liver damages. Methods Mol Biol 826, 89, 2012
14. Brimble, S.N. Sherrer, E.S., Uhl, E.W., Wang, E., Kelly, S., Merrill, A.H. Jr., Robins, A.J., and Schulz, T.C. The cell surface glycosphingolipids SSEA-3 and SSEA-4 are not essential for human ESC pluripotency. Stem Cells 25, 54, 2007
15. Tong, C.K., Vellasamy, S., Tan, B.C., Abdullah, M., Vidyadaran, S., Seow, H.F., et al. Generation of mesenchymal stem cell from human umbilical cord tissue using a combination enzymatic and mechanical disassociation method. Cell Biol Int 35, 221, 2011
16. Lee, K.S., Nah, J.J., Lee, B.C., Lee, H.T., Lee, H.S., So, B.J., et al. Maintenance and characterization of multipotent mesenchymal stem cells isolated from canine umbilical cord matrix by collagenase digestion. Res Vet Sci 94, 144, 2013
17. Takahashi, K., Tanabe, K.,Ohnuki, M.,Narita, M., Ichisaka, T., Tomoda,K., et al. Induction of pluripotent stemcells fromadult human fibroblasts by defined factors. Cell 131, 861, 2007
18. Wulsten, D., Glatt, V., Ellinghaus, A., Schmidt-Bleek, K., Petersen, A., Schell, H., et al. Time kinetics of bone defect healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics. Eur Cells Mater 21, 177, 2011
19. Agata, H., Asahina, I., Watanabe, N., Ishii, Y., Kubo, N., Ohshima, S., et al. Characteristic change and loss of in vivo osteogenic abilities of human bone marrow stromal cells during passage. Tissue Eng Part A 16, 663, 2010
20. Ramirez, J.M., Gerbal-Chaloin, S., Milhavet, O., Qiang, B., Becker, F., Assou, S., et al. Brief report: Benchmarking human pluripotent stem cell markers during differentiation into the three germ layers unveils a striking heterogeneity: All markers are not equal. Stem Cells 29, 1469, 2011
21. Draper, J.S., Pigott, C., Thomson, J.A., and Andrews, P.W. Surface antigens of human embryonic stem cells: Changes upon differentiation in culture. J Anat 200, 249, 2002
22. Rostovskaya, M., and Anastassiadis, K. Differential expression of surface markers in mouse bone marrow mesenchymal stromal cell subpopulations with distinct lineage commitment. PloS One 7, e51221, 2012
23. Schrobback, K., Wrobel, J., Hutmacher, D.W., Woodfield, T.B., and Klein, T.J. Stage-specific embryonic antigen-4 is not a marker for chondrogenic and osteogenic potential in cultured chondrocytes and mesenchymal progenitor cells. Tissue Eng Part A 19, 1316, 2013
24. Suila, H., Pitkanen, V., Hirvonen, T., Heiskanen, A., Anderson, H., Laitinen, A., et al. Are globoseries glycosphingolipids SSEA-3 and -4 markers for stem cells derived from human umbilical cord blood?. J Mol Cell Biol 3, 99, 2011.