The search for effective alzheimer's therapies: A work in progress

Health Affairs

Volumn 33, Issue 4, 2014, Pages 527-533

  Bor, Jonathan S ^a  

^a Health Affairs   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PROTEIN; TAU PROTEIN;

ALZHEIMER DISEASE; ARTICLE; HUMAN; MEDICAL RESEARCH; NONHUMAN; PREVENTIVE MEDICINE; PROTEIN ANALYSIS;

EID: 84898025729     PISSN: 02782715     EISSN: 15445208     Source Type: Journal    
DOI: 10.1377/hlthaff.2014.0183     Document Type: Article

References (20)

1. Department of Health and Human Services, Office of the Assistant Secretary for Planning and Evaluation. National Plan to Address Alzheimer's Disease [Internet]. Washington (DC): ASPE; [last updated 2012 May 14; cited 2014 Mar 4]. Available from: http://aspe.hhs.gov/ daltcp/napa/NatlPlan.pdf
2. Department of Health and Human Services, Office of the Assistant Secretary for Planning and Evaluation. National Plan to Address Alzheimer's Disease: 2013 update [Internet]. Washington (DC): ASPE; [last updated 2013 Jun 14; cited 2014 Mar 4]. Available from: http://aspe .hhs.gov/daltcp/napa/NatlPlan2013 .shtml
3. Cha AE. NIH announces novel venture with drug companies to fight major diseases. Washington Post. 2014 Feb. 4.
4. National Institute on Aging. 2012-2013 Alzheimer's disease progress report: seeking the earliest interventions [Internet]. Bethesda (MD): NIA; [cited 2014 Mar 4]. Available from: http://www.nia.nih.gov/ alzheimers/publication/2012-2013-alzheimers-disease-progress-report
5. Hurd MD, Martorell P, Delavande A, Mullen KJ, Langa KM. Monetary costs of dementia in the United States. N Engl J Med. 2013;368(14): 1326-34.
6. Hurd MD, Martorell P, Delavande A, Mullen KJ, Langa KM. Monetary costs of dementia in the United States. N Engl J Med. 2013; 368(14):1326-34.
7. Alzheimers Association. Treatment horizon: learning from families with rare Alzheimer-causing genetic changes [Internet]. Chicago (IL): Alzheimer's Association; [cited 2014 Mar 7]. Available from: http:// www.alz.org/research/science/ alzheimers_treatment_horizon.asp
8. National Institute on Aging. 2011-2012 Alzheimer's disease progress report: a primer on Alzheimer's disease and the brain [Internet]. Bethesda (MD): NIA; [cited 2014 Mar 4]. Available from: http:// www.nia.nih.gov/alzheimers/ publication/2011-2012-alzheimersdisease-progress-report/primeralzheimers-disease-and
9. Doody RS, Thomas RG, Farlow M, Iwatsubo T, Vellas B, Joffe S, et al. Phase 3 trials of solanezumab for mild-to-moderate Alzheimer's disease. N Engl J Med. 2014;370(4): 311-21.
10. Salloway S, Sperling R, Fox NC, Blennow K, Klunk W, Raskind M, et al. Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease. N Engl J Med. 2014;370(4):322-33.
11. Whalen J. An outcast among peers gains traction on Alzheimer's cure. Washington Post. 2012 Nov 9.
12. Craft S, Baker LD, Montine TJ, Minoshima S,Watson GS, Claxton A, et al. Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clinical trial. Arch Neurol. 2012; 69(1):29-38.
13. Science Daily. Finding Alzheimer's disease before symptoms start. Science Daily [serial on the Internet]. 2013 Oct 16 [cited 2014 Mar 4]. Available from: http://www.science daily.com/releases/2013/10/ 131016212445.htm
14. Mapstone M, Cheema AK, Fiandaca MS, Zhong X, Mhyre TR, MacArthur LH, et al. Plasma phospholipids identify antecedent memory impairment in older adults. Nat Med [serial on the Internet]. 2014 Mar 9 [accessed 2014 Mar 11]. Available from: http://www.nature.com/nm/ journal/vaop/ncurrent/full/nm .3466.html.
15. Bahrampour T. Blood test may predict onset of Alzheimer's and related disease, new study finds. Washington Post. 2014 Mar 10.
16. National Institutes of Health [Internet]. Bethesda (MD): NIH. Press release, Independent panel finds insufficient evidence to support preventive measures for Alzheimer's disease; 2010 Apr 28 [cited 2014 Mar 4]. Available from: http:// www.nih.gov/news/health/ apr2010/od-28.htm
17. Alzheimer's Association. Adopt a brain-healthy diet [Internet]. Chicago (IL): Alzheimer's Association; [cited 2014 Mar 4]. Available from: https://www.alz.org/we_can_help_ adopt_a_brain_healthy_diet.asp
18. Emanuel EJ. Alzheimer's anxiety. New York Times. 2013 Nov 16.
19. Centers for Medicare and Medicaid Services. Medicare national coverage determination (NCD) for beta amyloid positron emission tomography (PET) in dementia and neurodegenerative disease [Internet]. Baltimore (MD): CMS; [cited 2014 Mar 4]. Available from: http:// www.cms.gov/Outreach-and-Education/Medicare-Learning-Network-MLN/MLNMatters Articles/Downloads/MM8526.pdf
20. Alzheimers Association. Current Alzheimer's treatments [Internet]. Chicago (IL): Alzheimer's Association; [cited 2014 Mar 4]. Available from: http://www.alz.org/research/ science/alzheimers_disease_ treatments.asp#approved