Risk factors and consequences of maternal anaemia and elevated haemoglobin levels during pregnancy: A population-based prospective cohort study

Paediatric and Perinatal Epidemiology

Volumn 28, Issue 3, 2014, Pages 213-226

  Gaillard, Romy ^a   Eilers, Paul H C ^b   Yassine, Siham ^a   Hofman, Albert ^a   Steegers, Eric A P ^b   Jaddoe, Vincent W V ^a  

^a SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

adverse birth outcomes; blood pressure; cohort study; fetal growth; gestational hypertension; haemoglobin; pre eclampsia; pregnancy

Indexed keywords

HEMOGLOBIN;

ADULT; ANEMIA; ARTERY DISEASE; ARTICLE; BODY HEIGHT; BODY MASS; COHORT ANALYSIS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; ETHNICITY; EUROPE; FEMALE; FETUS; FETUS GROWTH; FETUS OUTCOME; FETUS WEIGHT; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; GROWTH DISORDER; HEAD CIRCUMFERENCE; HEMOGLOBIN BLOOD LEVEL; HUMAN; LIFESTYLE; LOW BIRTH WEIGHT; LOW RISK POPULATION; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MATERNAL ANEMIA; MATERNAL DISEASE; MATERNAL HYPERTENSION; PLACENTA FUNCTION; PREECLAMPSIA; PREGNANCY COMPLICATION; PREGNANCY OUTCOME; PREMATURITY; PRIMIPARA; PROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SMALL FOR DATE INFANT; SPHYGMOMANOMETER; SYSTOLIC BLOOD PRESSURE; THIRD TRIMESTER PREGNANCY; UTERINE ARTERY; UTERINE ARTERY NOTCHING; WORLD HEALTH ORGANIZATION; EDUCATIONAL STATUS; FETUS DEVELOPMENT; HEMATOCRIT; METABOLISM; NEWBORN; PARITY; PLACENTAL INSUFFICIENCY; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PROCEDURES;

ADULT; ANEMIA; BODY MASS INDEX; EDUCATIONAL STATUS; FEMALE; FETAL DEVELOPMENT; GESTATIONAL AGE; HEMATOCRIT; HEMOGLOBINS; HUMANS; INFANT, NEWBORN; LIFE STYLE; MATERNAL AGE; PARITY; PLACENTAL INSUFFICIENCY; PREGNANCY; PREGNANCY COMPLICATIONS, HEMATOLOGIC; PREGNANCY OUTCOME; PREGNANCY TRIMESTERS; PROSPECTIVE STUDIES; RISK FACTORS;

EID: 84897990957     PISSN: 02695022     EISSN: 13653016     Source Type: Journal    
DOI: 10.1111/ppe.12112     Document Type: Article

References (40)

1. Murphy JF, O'Riordan J, Newcombe RG, Coles EC, Pearson JF,. Relation of haemoglobin levels in first and second trimesters to outcome of pregnancy. Lancet 1986; 1: 992-995.
2. Brabin BJ, Hakimi M, Pelletier D,. An analysis of anemia and pregnancy-related maternal mortality. Journal of Nutrition 2001; 131: 604S-614S.
3. Scholl TO, Hediger ML,. Anemia and iron-deficiency anemia: compilation of data on pregnancy outcome. American Journal of Clinical Nutrition 1994; 59: 492S-500S.
4. Garn SM, Keating MT, Falkner F,. Hematological status and pregnancy outcomes. American Journal of Clinical Nutrition 1981; 34: 115-117.
5. Steer P, Alam MA, Wadsworth J, Welch A,. Relation between maternal haemoglobin concentration and birth weight in different ethnic groups. British Medical Journal 1995; 310: 489-491.
6. Haider BA, Olofin I, Wang M, Spiegelman D, Ezzati M, Fawzi WW, et-al. Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis. British Medical Journal 2013; 346: f3443.
7. Rasmussen K,. Is there a causal relationship between iron deficiency or iron-deficiency anemia and weight at birth, length of gestation and perinatal mortality? Journal of Nutrition 2001; 131: 590S-601S.
8. Jaddoe VW, van Duijn CM, Franco OH, van der Heijden AJ, van Iizendoorn MH, de Jongste JC, et-al. The Generation R study: design and cohort update 2012. European Journal of Epidemiology 2012; 27: 739-756.
9. Jaddoe VW, Mackenbach JP, Moll HA, Steegers EA, Tiemeier H, Verhulst FC, et-al. The Generation R study: design and cohort profile. European Journal of Epidemiology 2006; 21: 475-484.
10. World Medical Association I. Declaration of Helsinki. Ethical principles for medical research involving human subjects. Journal of Indian Medical Association 2009; 107: 403-405.
11. Jaddoe VW, Bakker R, van Duijn CM, van der Heijden AJ, Lindemans J, Mackenbach JP, et-al. The Generation R Study Biobank: a resource for epidemiological studies in children and their parents. European Journal of Epidemiology 2007; 22: 917-923.
12. World Health Organization (WHO). Haemoglobin Concentrations for the Diagnosis of Anaemia and Assessment of Severity. Vitamin and Mineral Nutrition Information System. Geneva, World Health Organization, 2011 (WHO/NMH/NHD/MNM/11. 1). Available at: http://www.who.int/vmnis/indicators/haemoglobin.pdf [last accessed August 2012].
13. Heppe DH, Medina-Gomez C, Hofman A, Franco OH, Rivadeneira F, Jaddoe VW,. Maternal first-trimester diet and childhood bone mass: the Generation R Study. American Journal of Clinical Nutrition 2013; 98: 224-232.
14. El Assaad MA, Topouchian JA, Darne BM, Asmar RG,. Validation of the Omron HEM-907 device for blood pressure measurement. Blood Pressure Monitoring 2002; 7: 237-241.
15. Gaillard R, Bakker R, Willemsen SP, Hofman A, Steegers EA, Jaddoe VW,. Blood pressure tracking during pregnancy and the risk of gestational hypertensive disorders: the Generation R Study. European Heart Journal 2011; 32: 3088-3097.
16. Coolman M, de Groot CJ, Jaddoe VW, Hofman A, Raat H, Steegers EA,. Medical record validation of maternally reported history of preeclampsia. Journal of Clinical Epidemiology 2010; 63: 932-937.
17. Levine RJ, Lam C, Qian C, Yu KF, Maynard SE, Sachs BP, et-al. Soluble endoglin and other circulating antiangiogenic factors in preeclampsia. New England Journal of Medicine 2006; 355: 992-1005.
18. Coolman M, Timmermans S, de Groot CJ, Russcher H, Lindemans J, Hofman A, et-al. Angiogenic and fibrinolytic factors in blood during the first half of pregnancy and adverse pregnancy outcomes. Obstetrics and Gynecology 2012; 119: 1190-1200.
19. Gaillard R, Arends LR, Steegers EA, Hofman A, Jaddoe VW,. Second- and third-trimester placental hemodynamics and the risks of pregnancy complications: the Generation R Study. American Journal of Epidemiology 2013; 177: 743-754.
20. Rurangirwa AA, Gaillard R, Steegers EA, Hofman A, Jaddoe VW,. Hemodynamic adaptations in different trimesters among nulliparous and multiparous pregnant women; the Generation R study. American Journal of Hypertension 2012; 25: 892-899.
21. Verburg BO, Steegers EA, De Ridder M, Snijders RJ, Smith E, Hofman A, et-al. New charts for ultrasound dating of pregnancy and assessment of fetal growth: longitudinal data from a population-based cohort study. Ultrasound Obstetrics and Gynecology 2008; 31: 388-396.
22. Hadlock FP, Harrist RB, Sharman RS, Deter RL, Park SK,. Estimation of fetal weight with the use of head, body, and femur measurements-a prospective study. American Journal of Obstetrics and Gynecology 1985; 151: 333-337.
23. Niklasson A, Ericson A, Fryer JG, Karlberg J, Lawrence C, Karlberg P,. An update of the Swedish reference standards for weight, length and head circumference at birth for given gestational age (1977-1981). Acta Paediatrica Scandinavica 1991; 80: 756-762.
24. Royston P, Ambler G, Sauerbrei W,. The use of fractional polynomials to model continuous risk variables in epidemiology. International Journal of Epidemiology 1999; 28: 964-974.
25. Goldstein H,. Multilevel Statistical Methods, 2nd edn. London: Edward Arnold, 1995.
26. Xiong X, Buekens P, Alexander S, Demianczuk N, Wollast E,. Anemia during pregnancy and birth outcome: a meta-analysis. American Journal of Perinatology 2000; 17: 137-146.
27. Sterne JA, White IR, Carlin JB, Spratt M, Royston P, Kenward MG, et-al. Multiple imputation for missing data in epidemiological and clinical research: potential and pitfalls. British Medical Journal 2009; 338: b2393.
28. Selo-Ojeme DO,. Anemia in pregnancy: case control study of risk factors. International Journal of Gynaecology and Obstetrics 1997; 59: 53-54.
29. Ahmed F, Al-Sumaie MA,. Risk factors associated with anemia and iron deficiency among Kuwaiti pregnant women. International Journal of Food Science and Nutrition 2011; 62: 585-592.
30. Weatherall DJ,. The definition and epidemiology of non-transfusion- dependent thalassemia. Blood Reviews 2012; 26 (Suppl. 1): S3-S6.
31. Redman CW,. Maternal plasma volume and disorders of pregnancy. British Medical Journal (Clin Res Ed) 1984; 288: 955-956.
32. Knottnerus JA, Delgado LR, Knipschild PG, Essed GG, Smits F,. Haematologic parameters and pregnancy outcome. A prospective cohort study in the third trimester. Journal of Clinical Epidemiology 1990; 43: 461-466.
33. Steegers EA, von Dadelszen P, Duvekot JJ, Pijnenborg R,. Pre-eclampsia. Lancet 2010; 376: 631-644.
34. Huisman A, Aarnoudse JG,. Increased 2nd trimester hemoglobin concentration in pregnancies later complicated by hypertension and growth retardation. Early evidence of a reduced plasma volume. Acta Obstetricia et Gynecologica Scandinavica 1986; 65: 605-608.
35. Tranquilli AL, Landi B,. The origin of pre-eclampsia: from decidual 'hyperoxia' to late hypoxia. Medical Hypotheses 2010; 75: 38-46.
36. Naeye RL,. Placental infarction leading to fetal or neonatal death. A prospective study. Obstetrics and Gynecology 1977; 50: 583-588.
37. Stephansson O, Dickman PW, Johansson A, Cnattingius S,. Maternal hemoglobin concentration during pregnancy and risk of stillbirth. Journal of the American Medical Association 2000; 284: 2611-2617.
38. Pena-Rosas JP, De-Regil LM, Dowswell T, Viteri FE,. Daily oral iron supplementation during pregnancy. Cochrane Database Systematic Reviews 2012; 12: CD004736.
39. Gonzales GF, Tapia V, Gasco M, Carrillo CE,. Maternal hemoglobin concentration and adverse pregnancy outcomes at low and moderate altitudes in Peru. Journal of Maternal-Fetal and Neonatal Medicine 2012; 25: 1105-1110.
40. Nohr EA, Frydenberg M, Henriksen TB, Olsen J,. Does low participation in cohort studies induce bias? Epidemiology (Cambridge, Mass.) 2006; 17: 413-418.