Metabolic profiles of biological aging in american indians: The strong heart family study

Aging

Volumn 6, Issue 3, 2014, Pages 176-186

  Zhao, Jinying ^a   Zhu, Yun ^a   Uppal, Karan ^b   Tran, ViLinh T ^b   Yu, Tianwei ^c   Lin, Jue ^d   Matsuguchi, Tet ^d   Blackburn, Elizabeth ^d   Jones, Dean ^b   Lee, Elisa T ^e   Howard, Barbara V ^f  

^a TULANE UNIVERSITY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c EMORY UNIVERSITY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^f Delaware   (United States)

Author keywords

American indians; Metabolic profiles; Metabolomics; Telomere length; Telomeric age

Indexed keywords

BIOLOGICAL MARKER;

ADOLESCENT; ADULT; AGED; AGING; AMERICAN INDIAN; FEMALE; GENETICS; HEART DISEASE; HUMAN; LEUKOCYTE; MALE; METABOLISM; METABOLOME; MIDDLE AGED; TELOMERE; TELOMERE HOMEOSTASIS; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGING; BIOLOGICAL MARKERS; FEMALE; HEART DISEASES; HUMANS; INDIANS, NORTH AMERICAN; LEUKOCYTES; MALE; METABOLOME; MIDDLE AGED; TELOMERE; TELOMERE HOMEOSTASIS; YOUNG ADULT;

EID: 84897990879     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100644     Document Type: Article

References (56)

1. Van Pelt RE, Jones PP, Davy KP, Desouza CA, Tanaka H, Davy BM and Seals DR. Regular exercise and the age-related decline in resting metabolic rate in women. The Journal of clinical endocrinology and metabolism. 1997; 82:3208-3212.
2. Roder ME, Schwartz RS, Prigeon RL and Kahn SE. Reduced pancreatic B cell compensation to the insulin resistance of aging: impact on proinsulin and insulin levels. The Journal of clinical endocrinology and metabolism. 2000; 85:2275-2280.
3. Iozzo P, Beck-Nielsen H, Laakso M, Smith U, Yki-Jarvinen H and Ferrannini E. Independent influence of age on basal insulin secretion in nondiabetic humans. European Group for the Study of Insulin Resistance. The Journal of clinical endocrinology and metabolism. 1999; 84:863-868.
4. Maher P. The effects of stress and aging on glutathione metabolism. Ageing research reviews. 2005; 4:288-314.
5. Barzilai N, Huffman DM, Muzumdar RH and Bartke A. The critical role of metabolic pathways in aging. Diabetes. 2012; 61:1315-1322.
6. Feldser DM, Hackett JA and Greider CW. Telomere dysfunction and the initiation of genome instability. Nature reviews Cancer. 2003; 3:623-627.
7. Levine TB and Levine AB. 2012. Telomeres. Metabolic Syndrome and Cardiovascular Disease: Wiley-Blackwell).
8. Sahin E, Colla S, Liesa M, Moslehi J, Muller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C, Maser RS, Tonon G, Foerster F, et al. Telomere dysfunction induces metabolic and mitochondrial compromise. Nature. 2011; 470:359-365.
9. Gan B, Hu J, Jiang S, Liu Y, Sahin E, Zhuang L, Fletcher-Sananikone E, Colla S, Wang YA, Chin L and Depinho RA. Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature. 2010; 468:701-704.
10. Tomas-Loba A, Bernardes de Jesus B, Mato JM and Blasco MA. A metabolic signature predicts biological age in mice. Aging cell. 2013; 12:93-101.
11. Bernardes de Jesus B, Vera E, Schneeberger K, Tejera AM, Ayuso E, Bosch F and Blasco MA. Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer. EMBO molecular medicine. 2012; 4:691-704.
12. Moreno-Navarrete JM, Ortega F, Sabater M, Ricart W and Fernandez-Real JM. Telomere length of subcutaneous adipose tissue cells is shorter in obese and formerly obese subjects. Int J Obes (Lond). 2010; 34:1345-1348.
13. Salpea KD and Humphries SE. Telomere length in atherosclerosis and diabetes. Atherosclerosis. 2010; 209:35-38.
14. Gardner JP, Li S, Srinivasan SR, Chen W, Kimura M, Lu X, Berenson GS and Aviv A. Rise in insulin resistance is associated with escalated telomere attrition. Circulation. 2005; 111:2171-2177.
15. Adaikalakoteswari A, Balasubramanyam M, Ravikumar R, Deepa R and Mohan V. Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy. Atherosclerosis. 2007; 195:83-89.
16. O'Donnell CJ, Demissie S, Kimura M, Levy D, Gardner JP, White C, D'Agostino RB, Wolf PA, Polak J, Cupples LA and Aviv A. Leukocyte telomere length and carotid artery intimal medial thickness: the Framingham Heart Study. Arterioscler Thromb Vasc Biol. 2008; 28:1165-1171.
17. Harte AL, da Silva NF, Miller MA, Cappuccio FP, Kelly A, O'Hare JP, Barnett AH, Al-Daghri NM, Al-Attas O, Alokail M, Sabico S, Tripathi G, Bellary S, et al. Telomere length attrition, a marker of biological senescence, is inversely correlated with triglycerides and cholesterol in South Asian males with type 2 diabetes mellitus. Experimental diabetes research. 2012; 2012:895185.
18. Yang Z, Huang X, Jiang H, Zhang Y, Liu H, Qin C, Eisner GM, Jose PA, Rudolph L and Ju Z. Short telomeres and prognosis of hypertension in a chinese population. Hypertension. 2009; 53:639-645.
19. Zhao J, Zhu Y, Lin J, Matsuguchi T, Blackburn E, Zhang Y, Cole SA, Best LG, Lee ET and Howard BV. Short leukocyte telomere length predicts risk of diabetes in american indians: the strong heart family study. Diabetes. 2014; 63:354-362.
20. Bain JR, Stevens RD, Wenner BR, Ilkayeva O, Muoio DM and Newgard CB. Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes. 2009; 58:2429-2443.
21. Houtkooper RH, Argmann C, Houten SM, Canto C, Jeninga EH, Andreux PA, Thomas C, Doenlen R, Schoonjans K and Auwerx J. The metabolic footprint of aging in mice. Scientific reports. 2011; 1:134.
22. Takiyama N and Matsumoto K. Age-and sex-related differences of serum carnitine in a Japanese population. Journal of the American College of Nutrition. 1998; 17:71-74.
23. Yu Z, Zhai G, Singmann P, He Y, Xu T, Prehn C, Romisch-Margl W, Lattka E, Gieger C, Soranzo N, Heinrich J, Standl M, Thiering E, et al. Human serum metabolic profiles are age dependent. Aging cell. 2012; 11:960-967.
24. Lee ET, Welty TK, Fabsitz R, Cowan LD, Le NA, Oopik AJ, Cucchiara AJ, Savage PJ and Howard BV. The Strong Heart Study. A study of cardiovascular disease in American Indians: design and methods. Am J Epidemiol. 1990; 132:1141-1155.
25. Mellitus TECotDaCoD. 2002. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. pp. s5-s20
26. Willett W. 1998. Food frequency methods. Nutritional Epidemiology. (New York, NY: Oxford University Press), pp. 74-91.
27. Cawthon RM. Telomere measurement by quantitative PCR. Nucleic acids research. 2002; 30:e47.
28. Lin J, Epel E, Cheon J, Kroenke C, Sinclair E, Bigos M, Wolkowitz O, Mellon S and Blackburn E. Analyses and comparisons of telomerase activity and telomere length in human T and B cells: insights for epidemiology of telomere maintenance. Journal of immunological methods. 2010; 352:71-80.
29. Osborn MP, Park Y, Parks MB, Burgess LG, Uppal K, Lee K, Jones DP and Brantley MA, Jr. Metabolome-wide association study of neovascular age-related macular degeneration. PloS one. 2013; 8:e72737.
30. Ungvari Z, Parrado-Fernandez C, Csiszar A and de Cabo R. Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. Circulation research. 2008; 102:519-528.
31. Yu T, Park Y, Johnson JM and Jones DP. apLCMS--adaptive processing of high-resolution LC/MS data. Bioinformatics. 2009; 25:1930-1936.
32. Smith CA, O'Maille G, Want EJ, Qin C, Trauger SA, Brandon TR, Custodio DE, Abagyan R and Siuzdak G. METLIN: a metabolite mass spectral database. Therapeutic drug monitoring. 2005; 27:747-751.
33. Wishart DS, Jewison T, Guo AC, Wilson M, Knox C, Liu Y, Djoumbou Y, Mandal R, Aziat F, Dong E, Bouatra S, Sinelnikov I, Arndt D, et al. HMDB 3.0--The Human Metabolome Database in 2013. Nucleic acids research. 2013; 41:D801-807.
34. Sud M, Fahy E, Cotter D, Brown A, Dennis EA, Glass CK, Merrill AH, Jr., Murphy RC, Raetz CR, Russell DW and Subramaniam S. LMSD: LIPID MAPS structure database. Nucleic acids research. 2007; 35:D527-532.
35. Hughes G, Cruickshank-Quinn C, Reisdorph R, Lutz S, Petrache I, Reisdorph N, Bowler R and Kechris K. MSPrep--Summarization, normalization and diagnostics for processing of mass spectrometry-based metabolomic data. Bioinformatics. 2014; 30:133-134.
36. Storey JD. A direct approach to false discovery rates. J R Stat Soc B. 2002; 64:187-205.
37. Brites P, Waterham HR and Wanders RJ. Functions and biosynthesis of plasmalogens in health and disease. Biochimica et biophysica acta. 2004; 1636:219-231.
38. Wood PL. Lipidomics of Alzheimer's disease: current status. Alzheimer's research&therapy. 2012; 4:5.
39. Lessig J and Fuchs B. Plasmalogens in biological systems: their role in oxidative processes in biological membranes, their contribution to pathological processes and aging and plasmalogen analysis. Current medicinal chemistry. 2009; 16:2021-2041.
40. Amenta F, Parnetti L, Gallai V and Wallin A. Treatment of cognitive dysfunction associated with Alzheimer's disease with cholinergic precursors. Ineffective treatments or inappropriate approaches? Mechanisms of ageing and development. 2001; 122:2025-2040.
41. Li T and Chiang JY. Bile Acid signaling in liver metabolism and diseases. Journal of lipids. 2012; 2012:754067.
42. Goldberg AA, Richard VR, Kyryakov P, Bourque SD, Beach A, Burstein MT, Glebov A, Koupaki O, Boukh-Viner T, Gregg C, Juneau M, English AM, Thomas DY, et al. Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. Aging. 2010; 2:393-414.
43. Gerisch B, Rottiers V, Li D, Motola DL, Cummins CL, Lehrach H, Mangelsdorf DJ and Antebi A. A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proceedings of the National Academy of Sciences of the United States of America. 2007; 104:5014-5019.
44. Bertolotti M, Gabbi C, Anzivino C, Crestani M, Mitro N, Del Puppo M, Godio C, De Fabiani E, Macchioni D, Carulli L, Rossi A, Ricchi M, Loria P, et al. Age-related changes in bile acid synthesis and hepatic nuclear receptor expression. European journal of clinical investigation. 2007; 37:501-508.
45. O'Sullivan RJ and Karlseder J. Telomeres: protecting chromosomes against genome instability. Nature reviews Molecular cell biology. 2010; 11:171-181.
46. Schmid HH and Berdyshev EV. Cannabinoid receptor-inactive N-acylethanolamines and other fatty acid amides: metabolism and function. Prostaglandins, leukotrienes, and essential fatty acids. 2002; 66:363-376.
47. Dang HT, Kang GJ, Yoo ES, Hong J, Choi JS, Kim HS, Chung HY and Jung JH. Evaluation of endogenous fatty acid amides and their synthetic analogues as potential anti-inflammatory leads. Bioorganic&medicinal chemistry. 2011; 19:1520-1527.
48. Meijers BK, de Loor H, Verbeke K and Evenepoel P. p-Cresol for better or worse: but what are we measuring? Kidney international. 2006; 70(1):232; author reply 232-233.
49. Ujhelyi L, Balla G, Jeney V, Varga Z, Nagy E, Vercellotti GM, Agarwal A, Eaton JW and Balla J. Hemodialysis reduces inhibitory effect of plasma ultrafiltrate on LDL oxidation and subsequent endothelial reactions. Kidney international. 2006; 69:144-151.
50. Erion DM and Shulman GI. Diacylglycerol-mediated insulin resistance. Nature medicine. 2010; 16:400-402.
51. Itani SI, Ruderman NB, Schmieder F and Boden G. Lipidinduced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IkappaB-alpha. Diabetes. 2002; 51:2005-2011.
52. Greer EL and Brunet A. Signaling networks in aging. Journal of cell science. 2008; 121:407-412.
53. Lupien SJ, de Leon M, de Santi S, Convit A, Tarshish C, Nair NP, Thakur M, McEwen BS, Hauger RL and Meaney MJ. Cortisol levels during human aging predict hippocampal atrophy and memory deficits. Nature neuroscience. 1998; 1:69-73.
54. Costell M, O'Connor JE and Grisolia S. Age-dependent decrease of carnitine content in muscle of mice and humans. Biochemical and biophysical research communications. 1989; 161:1135-1143.
55. Hagen TM, Ingersoll RT, Wehr CM, Lykkesfeldt J, Vinarsky V, Bartholomew JC, Song MH and Ames BN. Acetyl-L-carnitine fed to old rats partially restores mitochondrial function and ambulatory activity. Proceedings of the National Academy of Sciences of the United States of America. 1998; 95:9562-9566.
56. Chakrabarti S, Jahandideh F and Wu J. Food-Derived Bioactive Peptides on Inflammation and Oxidative Stress. BioMed research international. 2014; 2014:608979.