메뉴 건너뛰기




Volumn 9, Issue 1, 2014, Pages

Furin is the major proprotein convertase required for KISS1-to-Kisspeptin processing

Author keywords

[No Author keywords available]

Indexed keywords

FURIN; KISSPEPTIN; MESSENGER RNA; METASTIN; PROTEIN PCSK5; PROTEIN PCSK7; SERINE PROTEINASE; UNCLASSIFIED DRUG;

EID: 84897975795     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084958     Document Type: Article
Times cited : (22)

References (37)
  • 2
    • 83555176139 scopus 로고    scopus 로고
    • Neuroendocrine control by kisspeptins: Role in metabolic regulation of fertility
    • nrendo.2011.147 [pii]; 10.1038/nrendo.2011.147 [doi]
    • Navarro VM, Tena-Sempere M (2012) Neuroendocrine control by kisspeptins: role in metabolic regulation of fertility. Nature Reviews Endocrinology 8: 40-53. nrendo.2011.147 [pii];10.1038/nrendo.2011.147 [doi].
    • (2012) Nature Reviews Endocrinology , vol.8 , pp. 40-53
    • Navarro, V.M.1    Tena-Sempere, M.2
  • 3
    • 84864067222 scopus 로고    scopus 로고
    • Kisspeptins and reproduction: Physiological roles and regulatory mechanisms
    • 92/3/1235 [pii]; 10.1152/physrev.00037.2010 [doi]
    • Pinilla L, Aguilar E, Dieguez C, Millar RP, Tena-Sempere M (2012) Kisspeptins and reproduction: physiological roles and regulatory mechanisms. Physiol Rev 92: 1235-1316. 92/3/1235 [pii];10.1152/physrev.00037.2010 [doi].
    • (2012) Physiol Rev , vol.92 , pp. 1235-1316
    • Pinilla, L.1    Aguilar, E.2    Dieguez, C.3    Millar, R.P.4    Tena-Sempere, M.5
  • 4
    • 84857126496 scopus 로고    scopus 로고
    • Inactivating KISS1 mutation and hypogonadotropic hypogonadism
    • 10.1056/NEJMoa1111184 [doi]
    • Topaloglu AK, Tello JA, Kotan LD, Ozbek MN, Yilmaz MB, et al. (2012) Inactivating KISS1 mutation and hypogonadotropic hypogonadism. NEJM 366: 629-635. 10.1056/NEJMoa1111184 [doi].
    • (2012) NEJM , vol.366 , pp. 629-635
    • Topaloglu, A.K.1    Tello, J.A.2    Kotan, L.D.3    Ozbek, M.N.4    Yilmaz, M.B.5
  • 5
    • 84857126496 scopus 로고    scopus 로고
    • Inactivating KISS1 mutation and hypogonadotropic hypogonadism
    • 10.1056/NEJMoa1111184 [doi]
    • Topaloglu AK, Tello JA, Kotan LD, Ozbek MN, Yilmaz MB, et al. (2012) Inactivating KISS1 mutation and hypogonadotropic hypogonadism. N Engl J Med 366: 629-635. 10.1056/NEJMoa1111184 [doi].
    • (2012) N Engl J Med , vol.366 , pp. 629-635
    • Topaloglu, A.K.1    Tello, J.A.2    Kotan, L.D.3    Ozbek, M.N.4    Yilmaz, M.B.5
  • 7
    • 84860433921 scopus 로고    scopus 로고
    • Chronic exogenous kisspeptin administration accelerates gonadal development in basses of the genus Morone
    • S1095-6433(12)00076-1 [pii]; 10.1016/j.cbpa.2012.03.019 [doi]
    • Beck BH, Fuller SA, Peatman E, McEntire ME, Darwish A, et al. (2012) Chronic exogenous kisspeptin administration accelerates gonadal development in basses of the genus Morone. Comp Biochem Physiol [A] 162: 265-273. S1095-6433(12)00076-1 [pii];10.1016/j.cbpa.2012.03.019 [doi].
    • (2012) Comp Biochem Physiol [A] , vol.162 , pp. 265-273
    • Beck, B.H.1    Fuller, S.A.2    Peatman, E.3    McEntire, M.E.4    Darwish, A.5
  • 8
    • 73349105562 scopus 로고    scopus 로고
    • Neuroendocrinology of reproduction in teleost fish
    • S0016-6480(09)00168-3 [pii]; 10.1016/j.ygcen.2009.04.017 [doi]
    • Zohar Y, Munoz-Cueto JA, Elizur A, Kah O (2010) Neuroendocrinology of reproduction in teleost fish. Gen Comp Endocrinol 165: 438-455. S0016-6480(09)00168-3 [pii];10.1016/j.ygcen.2009.04.017 [doi].
    • (2010) Gen Comp Endocrinol , vol.165 , pp. 438-455
    • Zohar, Y.1    Munoz-Cueto, J.A.2    Elizur, A.3    Kah, O.4
  • 9
    • 32944469603 scopus 로고    scopus 로고
    • The KISS1 metastasis suppressor: Mechanistic insights and clinical utility
    • Nash KT, Welch DR (2006) The KISS1 metastasis suppressor: mechanistic insights and clinical utility. Front Biosci 11: 647-659. (Pubitemid 43258169)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.1 P.447-888 , pp. 647-659
    • Nash, K.T.1    Welch, D.R.2
  • 10
    • 77950580049 scopus 로고    scopus 로고
    • The KISS1 metastasis suppressor: A good night kiss for disseminated cancer cells
    • S0959-8049(10)00150-4 [pii]; 10.1016/j.ejca.2010.02.023 [doi]
    • Beck BH, Welch DR (2010) The KISS1 metastasis suppressor: a good night kiss for disseminated cancer cells. Eur J Cancer 46: 1283-1289. S0959-8049(10)00150-4 [pii];10.1016/j.ejca.2010.02.023 [doi].
    • (2010) Eur J Cancer , vol.46 , pp. 1283-1289
    • Beck, B.H.1    Welch, D.R.2
  • 12
    • 84867811973 scopus 로고    scopus 로고
    • Chronic administration of the metastin/kisspeptin analog KISS1-305 or the investigational agent TAK-448 suppresses hypothalamic pituitary gonadal function and depletes plasma testosterone in adult male rats
    • en.2012-1388 [pii]; 10.1210/en.2012-1388 [doi]
    • Matsui H, Tanaka A, Yokoyama K, Takatsu Y, Ishikawa K, et al. (2012) Chronic administration of the metastin/kisspeptin analog KISS1-305 or the investigational agent TAK-448 suppresses hypothalamic pituitary gonadal function and depletes plasma testosterone in adult male rats. Endocrinol 153: 5297-5308. en.2012-1388 [pii];10.1210/en.2012-1388 [doi].
    • (2012) Endocrinol , vol.153 , pp. 5297-5308
    • Matsui, H.1    Tanaka, A.2    Yokoyama, K.3    Takatsu, Y.4    Ishikawa, K.5
  • 14
    • 67649881029 scopus 로고    scopus 로고
    • In vivo and in vitro structure-activity relationships and structural conformation of Kisspeptin-10-related peptides
    • mol.108.053751 [pii]; 10.1124/mol.108.053751 [doi]
    • Gutierrez-Pascual E, Leprince J, Martinez-Fuentes AJ, Segalas-Milazzo I, Pineda R, et al. (2009) In vivo and in vitro structure-activity relationships and structural conformation of Kisspeptin-10-related peptides. Mol Pharmacol 76: 58-67. mol.108.053751 [pii];10.1124/mol.108.053751 [doi].
    • (2009) Mol Pharmacol , vol.76 , pp. 58-67
    • Gutierrez-Pascual, E.1    Leprince, J.2    Martinez-Fuentes, A.J.3    Segalas-Milazzo, I.4    Pineda, R.5
  • 16
    • 80054752024 scopus 로고    scopus 로고
    • The proprotein convertases, 20 years later
    • 10.1007/978-1-61779-204-5-3 [doi]
    • Seidah NG (2011) The proprotein convertases, 20 years later. Methods Mol Biol 768: 23-57. 10.1007/978-1-61779-204-5-3 [doi].
    • (2011) Methods Mol Biol , vol.768 , pp. 23-57
    • Seidah, N.G.1
  • 17
    • 79952466610 scopus 로고    scopus 로고
    • What lies ahead for the proprotein convertases?
    • 10.1111/j.1749-6632.2010.05883.x [doi]
    • Seidah NG (2011) What lies ahead for the proprotein convertases? Ann N Y Acad Sci 1220: 149-161. 10.1111/j.1749-6632.2010.05883.x [doi].
    • (2011) Ann N Y Acad Sci , vol.1220 , pp. 149-161
    • Seidah, N.G.1
  • 18
    • 43049141452 scopus 로고    scopus 로고
    • The activation and physiological functions of the proprotein convertases
    • S1357-2725(08)00043-5 [pii]; 10.1016/j.biocel.2008.01.030 [doi]
    • Seidah NG, Mayer G, Zaid A, Rousselet E, Nassoury N, et al. (2008) The activation and physiological functions of the proprotein convertases. Int J Biochem Cell Biol 40: 1111-1125. S1357-2725(08)00043-5 [pii];10.1016/j.biocel. 2008.01.030 [doi].
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 1111-1125
    • Seidah, N.G.1    Mayer, G.2    Zaid, A.3    Rousselet, E.4    Nassoury, N.5
  • 19
    • 84860383419 scopus 로고    scopus 로고
    • The biology and therapeutic targeting of the proprotein convertases
    • nrd3699 [pii]; 10.1038/nrd3699 [doi]
    • Seidah NG, Prat A (2012) The biology and therapeutic targeting of the proprotein convertases. Nature Drug Discovery 11: 367-383. nrd3699 [pii];10.1038/nrd3699 [doi].
    • (2012) Nature Drug Discovery , vol.11 , pp. 367-383
    • Seidah, N.G.1    Prat, A.2
  • 20
    • 33750109567 scopus 로고    scopus 로고
    • Proprotein convertases: Lessons from knockouts
    • DOI 10.1096/fj.05-5491rev
    • Scamuffa N, Calvo F, Chretien M, Seidah NG, Khatib AM (2006) Proprotein convertases: lessons from knockouts. FASEB J 20: 1954-1963. (Pubitemid 44953895)
    • (2006) FASEB Journal , vol.20 , Issue.12 , pp. 1954-1963
    • Scamuffa, N.1    Calvo, F.2    Chretien, M.3    Seidah, N.G.4    Khatib, A.-M.5
  • 21
    • 0026019465 scopus 로고
    • Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell line
    • Welch DR, Bisi JE, Miller BE, Conaway D, Seftor EA, et al. (1991) Characterization of a highly invasive and spontaneously metastatic human malignant melanoma cell line. Int J Cancer 47: 227-237.
    • (1991) Int J Cancer , vol.47 , pp. 227-237
    • Welch, D.R.1    Bisi, J.E.2    Miller, B.E.3    Conaway, D.4    Seftor, E.A.5
  • 22
    • 0019840456 scopus 로고
    • Surface antigens of human melanoma cells defined by monoclonal antibodies. I. Biochemical characterization of two antigens found on cell lines and fresh tumors of diverse tissue origin
    • Johnson JP, Demmer-Dieckmann M, Meo T, Hadam MR, Reithmuller G (1981) Surface antigens of human melanoma cells defined by monoclonal antibodies I. Biochemical characterization of two antigens found on cell lines and fresh tumors of diverse tissue origin. Eur J Immunol 11: 825-831. (Pubitemid 12237983)
    • (1981) European Journal of Immunology , vol.11 , Issue.10 , pp. 825-831
    • Johnson, J.P.1    Demmer-Dieckmann, M.2    Meo, T.3
  • 24
    • 0018236173 scopus 로고
    • Long-term human breast carcinoma cell lines of metastatic origin: Preliminary characterization
    • Cailleau R, Olive M, Cruciger QVJ (1978) Long-term human breast carcinoma cell lines of metastatic origin: preliminary characterization. In Vitro 14: 911-915. (Pubitemid 9089089)
    • (1978) In Vitro , vol.14 , Issue.11 , pp. 911-915
    • Cailleau, R.1    Olive, M.2    Cruciger, Q.V.J.3
  • 25
    • 84863167331 scopus 로고    scopus 로고
    • Clinical and biological significance of KISS1 expression in prostate cancer
    • Wang HH, Jones J, Turner T, He QHP, Hardy S, et al. (2012) Clinical and biological significance of KISS1 expression in prostate cancer. Am J Pathol 180: 1170-1178.
    • (2012) Am J Pathol , vol.180 , pp. 1170-1178
    • Wang, H.H.1    Jones, J.2    Turner, T.3    He, Q.H.P.4    Hardy, S.5
  • 26
    • 0028815633 scopus 로고
    • A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation
    • Takahashi S, Nakagawa T, Kasai K, Banno T, Duguay SJ, et al. (1995) A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation. J Biol Chem 270: 26565-26569.
    • (1995) J Biol Chem , vol.270 , pp. 26565-26569
    • Takahashi, S.1    Nakagawa, T.2    Kasai, K.3    Banno, T.4    Duguay, S.J.5
  • 27
    • 0027304393 scopus 로고
    • A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells
    • S0006-291X(83)72146-7 [pii]; 10.1006/bbrc.1993.2146 [doi]
    • Takahashi S, Kasai K, Hatsuzawa K, Kitamura N, Misumi Y, et al. (1993) A mutation of furin causes the lack of precursor-processing activity in human colon carcinoma LoVo cells. Biochem Biophys Res Commun 195: 1019-1026. S0006-291X(83)72146-7 [pii];10.1006/bbrc.1993.2146 [doi].
    • (1993) Biochem Biophys Res Commun , vol.195 , pp. 1019-1026
    • Takahashi, S.1    Kasai, K.2    Hatsuzawa, K.3    Kitamura, N.4    Misumi, Y.5
  • 28
    • 84898013960 scopus 로고    scopus 로고
    • In vitro activities of Kissorphin, a novel hexapeptide KiSS-1 derivative, in neuronal cells
    • 691463. 10.1155/2012/691463 [doi]
    • Milton NG (2012) In vitro activities of Kissorphin, a novel hexapeptide KiSS-1 derivative, in neuronal cells. J Amino Acids 2012: 691463. 10.1155/2012/691463 [doi].
    • (2012) J Amino Acids , vol.2012
    • Milton, N.G.1
  • 29
    • 0142057427 scopus 로고    scopus 로고
    • Bench and Bedside - The G Protein-Coupled Receptor GPR54 and Puberty
    • DOI 10.1056/NEJMp038155
    • Beier DR, Dluhy RG (2003) Bench and bedside - the G protein-coupled receptor GPR54 and puberty. N Engl J Med 349: 1589-1592. (Pubitemid 37288565)
    • (2003) New England Journal of Medicine , vol.349 , Issue.17 , pp. 1589-1592
    • Beier, D.R.1    Dluhy, R.G.2
  • 32
    • 79953209692 scopus 로고    scopus 로고
    • Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice
    • en.2010-1100 [pii]; 10.1210/en.2010-1100 [doi]
    • Quennell JH, Howell CS, Roa J, Augustine RA, Grattan DR, et al. (2011) Leptin deficiency and diet-induced obesity reduce hypothalamic kisspeptin expression in mice. Endocrinol 152: 1541-1550. en.2010-1100 [pii];10.1210/en. 2010-1100 [doi].
    • (2011) Endocrinol , vol.152 , pp. 1541-1550
    • Quennell, J.H.1    Howell, C.S.2    Roa, J.3    Augustine, R.A.4    Grattan, D.R.5
  • 33
    • 35948997633 scopus 로고    scopus 로고
    • Neuropeptide signaling in the integration of metabolism and reproduction
    • DOI 10.1159/000109095
    • Crown A, Clifton DK, Steiner RA (2007) Neuropeptide signaling in the integration of metabolism and reproduction. Neuroendocrinol 86: 175-182. (Pubitemid 350073605)
    • (2007) Neuroendocrinology , vol.86 , Issue.3 , pp. 175-182
    • Crown, A.1    Clifton, D.K.2    Steiner, R.A.3
  • 34
    • 33644659203 scopus 로고    scopus 로고
    • KiSS-1 neurones are direct targets for leptin in the ob/ob mouse
    • DOI 10.1111/j.1365-2826.2006.01417.x
    • Smith JT, Acohido BV, Clifton DK, Steiner RA (2006) KiSS-1 neurons are direct targets for leptin in the ob/ob mouse. J Neuroendo 18: 298-303. (Pubitemid 43323951)
    • (2006) Journal of Neuroendocrinology , vol.18 , Issue.4 , pp. 298-303
    • Smith, J.T.1    Acohido, B.V.2    Clifton, D.K.3    Steiner, R.A.4
  • 36
    • 23044450871 scopus 로고    scopus 로고
    • Reproductive biology - A powerful first KiSS-1
    • Vogel G (2005) Reproductive biology - A powerful first KiSS-1. Science 309: 551-552.
    • (2005) Science , vol.309 , pp. 551-552
    • Vogel, G.1
  • 37
    • 0042090268 scopus 로고    scopus 로고
    • Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases
    • DOI 10.1038/sj.onc.1206542
    • Takino T, Koshikawa N, Miyamori H, Tanaka M, Sasaki T, et al. (2003) Cleavage of metastasis suppressor gene product KiSS-1 protein/metastin by matrix metalloproteinases. Oncogene 22: 4617-4626. (Pubitemid 36976435)
    • (2003) Oncogene , vol.22 , Issue.30 , pp. 4617-4626
    • Takino, T.1    Koshikawa, N.2    Miyamori, H.3    Tanaka, M.4    Sasaki, T.5    Okada, Y.6    Seiki, M.7    Sato, H.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.