Administration of oral and vaginal prebiotic lactoferrin for a woman with a refractory vaginitis recurring preterm delivery: Appearance of lactobacillus in vaginal flora followed by term delivery

Journal of Obstetrics and Gynaecology Research

Volumn 40, Issue 2, 2014, Pages 583-585

  Otsuki, Katsufumi ^a   Tokunaka, Mayumi ^a   Oba, Tomohiro ^a   Nakamura, Masamitsu ^a   Shirato, Nahoko ^a   Okai, Takashi ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Bacterial vaginosis; Lactobacillus; Lactoferrin; Preterm delivery

Indexed keywords

ESTRIOL; LACTOFERRIN; METRONIDAZOLE; PREBIOTIC AGENT; ULINASTATIN;

ADULT; ARTICLE; BACTERIUM CULTURE; CASE REPORT; CHORIOAMNIONITIS; FEMALE; HUMAN; LACTOBACILLUS; PREMATURE FETUS MEMBRANE RUPTURE; PREMATURE LABOR; RECURRENT DISEASE; REFRACTORY VAGINITIS; SPONTANEOUS ABORTION; STREPTOCOCCUS AGALACTIAE; TABLET; UTERINE CERVIX CERCLAGE; VAGINA DISCHARGE; VAGINA FLORA; VAGINITIS; FETAL MEMBRANES, PREMATURE RUPTURE; MICROBIOLOGY; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREMATURE BIRTH; STREPTOCOCCAL INFECTIONS; VAGINA; VAGINOSIS, BACTERIAL;

ADULT; FEMALE; FETAL MEMBRANES, PREMATURE RUPTURE; HUMANS; LACTOBACILLUS; LACTOFERRIN; PREBIOTICS; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PREMATURE BIRTH; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS AGALACTIAE; VAGINA; VAGINOSIS, BACTERIAL;

EID: 84897975653     PISSN: 13418076     EISSN: 14470756     Source Type: Journal    
DOI: 10.1111/jog.12171     Document Type: Article

References (16)

1. Mikamo H, Kawazoe K, Sato Y, Tamaya T. Elastase activity of anaerobes isolated from amniotic fluid with preterm premature rupture of membranes. Am J Obstet Gynecol 1999; 180 (2 Pt 1): 378-380.
2. Sivanesaratnam V, Zainal SZ, Rachagan SP. A modified Shi-rodkar surgical closure of the incompetent cervix during pregnancy. Aust N Z J Obstet Gynaecol 1986; 26: 111-114.
3. Kaga N, Katsuki Y, Obata M, Shibutani Y. Repeated administration of low-dose lipopolysaccharide induces preterm delivery in mice:A model for human preterm parturition and for assessment of the therapeutic ability of drugs against preterm delivery. Am J Obstet Gynecol 1996; 174: 754-759.
4. Shimizu H. Development of an enteric-coated lactoferrin tablet and its application. Biometals 2004; 17: 343-347.
5. Ono T, Murakoshi M, Suzuki N et al. Potent anti-obesity effect of enteric-coated lactoferrin: Decrease in visceral fat accumulation in Japanese men and women with abdominal obesity after 8-week administration of enteric-coated lactof-errin tablets. Br J Nutr 2010; 104: 1688-1695.
6. Romero R, Yoon BH, Mazor M et al. The diagnostic and prognostic value of amniotic fluid white blood cell count, glucose, interleukin-6, and gram stain in patients with preterm labor and intact membranes. Am J Obstet Gynecol 1993; 169: 805-816.
7. Mitsuhashi Y, Otsuki K, Yoda A, Shimizu Y, Saito H, Yanaihara T. Effect of lactoferrin on lipopolysaccharide (LPS) induced preterm delivery in mice. Acta Obstet Gynecol Scand 2000; 79: 355-358.
8. Hasegawa A, Otsuki K, Sasaki Y et al. Preventive effect of recombinant human lactoferrin in a rabbit preterm delivery model. Am J Obstet Gynecol 2005; 192: 1038-1043.
9. Yakuwa K, Otsuki K, Nakayama K et al. Recombinant human lactoferrin has a potential to suppresses uterine cervical ripening in preterm delivery in animal model. Arch Gynecol Obstet 2007; 275: 331-334.
10. Nakayama K, Otsuki K, Yakuwa K et al. Recombinant human lactoferrin inhibits matrix metalloproteinase (MMP-2, MMP-3, and MMP-9) activity in a rabbit preterm delivery model. J Obstet Gynaecol Res 2008; 34: 931-934.
11. Machnicki M, Zimecki M, Zagulski T. Lactoferrin regulates the release of tumour necrosis factor alpha and interleukin 6 in vivo. Int J Exp Pathol 1993; 74: 433-439.
12. Giunta G, Giuffrida L, Mangano K, Fagone P, Cianci A. Influence of lactoferrin in preventing preterm delivery: A pilot study. Mol Med Rep 2012; 5: 162-166.
13. Paesano R, Pietropaoli M, Berlutti F, Valenti P. Bovine lactoferrin in preventing preterm delivery associated with sterile inflammation. Biochem Cell Biol 2012; 90: 468-475.
14. Zhang GH, Mann DM, Tsai CM. Neutralization of endotoxin in vitro and in vivo by a human lactoferrin-derived peptide. Infect Immun 1999; 67: 1353-1358.
15. Cottrell BH. An updated review of of evidence to discourage douching. MCN Am J Matern Child Nurs 2010; 35: 102-107. quiz 8-9.
16. Luong ML, Libman M, Dahhou M et al. Vaginal douching, bacterial vaginosis, and spontaneous preterm birth. J Obstet Gynaecol Can 2010; 32: 313-320.