-
1
-
-
34547586603
-
Guidelines on the irritable bowel syndrome: Mechanisms and practical management
-
DOI 10.1136/gut.2007.119446
-
Spiller R, Aziz Q, Creed F, et al. Guidelines on the irritable bowel syndrome: mechanisms and practical management. Gut 2007;56:1770-98. (Pubitemid 350206308)
-
(2007)
Gut
, vol.56
, Issue.12
, pp. 1770-1798
-
-
Spiller, R.1
Aziz, Q.2
Creed, F.3
Emmanuel, A.4
Houghton, L.5
Hungin, P.6
Jones, R.7
Kumar, D.8
Rubin, G.9
Trudgill, N.10
Whorwell, P.11
-
2
-
-
42549168553
-
Increased faecal serine protease activity in diarrhoeic IBS patients: A colonic lumenal factor impairing colonic permeability and sensitivity
-
Gecse K, Roka R, Ferrier L, et al. Increased faecal serine protease activity in diarrhoeic IBS patients: a colonic lumenal factor impairing colonic permeability and sensitivity. Gut 2008;57:591-9.
-
(2008)
Gut
, vol.57
, pp. 591-599
-
-
Gecse, K.1
Roka, R.2
Ferrier, L.3
-
3
-
-
0029022779
-
Altered rectal perception is a biological marker of patients with irritable bowel syndrome
-
Mertz H, Naliboff B, Munakata J, et al. Altered rectal perception is a biological marker of patients with irritable bowel syndrome. Gastroenterology 1995;109:40-52.
-
(1995)
Gastroenterology
, vol.109
, pp. 40-52
-
-
Mertz, H.1
Naliboff, B.2
Munakata, J.3
-
4
-
-
34247539019
-
A Pilot Study of Fecal Serine-Protease Activity: A Pathophysiologic Factor in Diarrhea-Predominant Irritable Bowel Syndrome
-
DOI 10.1016/j.cgh.2006.12.004, PII S1542356506012948
-
Roka R, Rosztoczy A, Leveque M, et al. A pilot study of fecal serine-protease activity: a pathophysiologic factor in diarrhea-predominant irritable bowel syndrome. Clin Gastroenterol Hepatol 2007;5:550-5. (Pubitemid 46660764)
-
(2007)
Clinical Gastroenterology and Hepatology
, vol.5
, Issue.5
, pp. 550-555
-
-
Roka, R.1
Rosztoczy, A.2
Leveque, M.3
Izbeki, F.4
Nagy, F.5
Molnar, T.6
Lonovics, J.7
Garcia-Villar, R.8
Fioramonti, J.9
Wittmann, T.10
Bueno, L.11
-
5
-
-
51849157847
-
Diagnostic performance of rapid tests for detection of fecal calprotectin and lactoferrin and their ability to discriminate inflammatory from irritable bowel syndrome
-
Otten CM, Kok L, Witteman BJ, et al. Diagnostic performance of rapid tests for detection of fecal calprotectin and lactoferrin and their ability to discriminate inflammatory from irritable bowel syndrome. Clin Chem Lab Med 2008;46:1275-80.
-
(2008)
Clin Chem Lab Med
, vol.46
, pp. 1275-1280
-
-
Otten, C.M.1
Kok, L.2
Witteman, B.J.3
-
6
-
-
84897961724
-
Origin of increased fecal serine protease in patients with irritable bowel syndrome and diarrhoea (IBS-D)
-
Garsed K, Singh G, Tooth D, et al. Origin of increased fecal serine protease in patients with irritable bowel syndrome and diarrhoea (IBS-D). Gut 2011;60:A25.
-
(2011)
Gut
, vol.60
-
-
Garsed, K.1
Singh, G.2
Tooth, D.3
-
7
-
-
0024239470
-
Contribution of the microflora to proteolysis in the human large intestine
-
MacFarlane GT, Allison C, Gibson SA, et al. Contribution of the microflora to proteolysis in the human large intestine. J Appl Bacteriol 1988;64:37-46. (Pubitemid 19003083)
-
(1988)
Journal of Applied Bacteriology
, vol.64
, Issue.1
, pp. 37-46
-
-
Macfarlane, G.T.1
Allison, C.2
Gibson, S.A.W.3
Cummings, J.H.4
-
8
-
-
84872850933
-
Ondansetron is an effective treatment for patients with diarrhoea predominant irritable bowel syndrome
-
Garsed K, Hastings M, Marciani L, et al. Ondansetron is an effective treatment for patients with diarrhoea predominant irritable bowel syndrome. Gut 2011;60(Suppl 3):A40.
-
(2011)
Gut
, vol.60
, Issue.SUPPL. 3
-
-
Garsed, K.1
Hastings, M.2
Marciani, L.3
-
9
-
-
84890186910
-
Mode of action of a macrogol formulation on distribution of intestinal fluid: A MRI study
-
Garsed KC, Marciani L, Fields A, et al. Mode of action of a macrogol formulation on distribution of intestinal fluid: a MRI study. Gastroenterology 2012;142:S814.
-
(2012)
Gastroenterology
, vol.142
-
-
Garsed, K.C.1
Marciani, L.2
Fields, A.3
-
10
-
-
0023265275
-
Simplified assessment of segmental colonic transit
-
Metcalf AM, Phillips SF, Zinsmeister AR, et al. Simpli fied assessment of segmental colonic transit. Gastroenterology 1987;92:40-7. (Pubitemid 17207659)
-
(1987)
Gastroenterology
, vol.92
, Issue.1
, pp. 40-47
-
-
Metcalf, A.M.1
Phillips, S.F.2
Zinsmeister, A.R.3
-
11
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-54.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.1
-
12
-
-
84897960691
-
An economical high-throughput protocol for multidimensional fractionation of proteins
-
Tooth DJ, Krishna VG, Layfield R. An economical high-throughput protocol for multidimensional fractionation of proteins. International Journal of Proteomics 2012;2012:735132.
-
(2012)
International Journal of Proteomics
, vol.2012
, pp. 735132
-
-
Tooth, D.J.1
Krishna, V.G.2
Layfield, R.3
-
13
-
-
0028983813
-
Improvement of an "In-Gel" digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing
-
Hellman U, Wernstedt C, Gonez J, et al. Improvement of an "In-Gel" digestion procedure for the micropreparation of internal protein fragments for amino acid sequencing. Anal Biochem 1995;224:451-5.
-
(1995)
Anal Biochem
, vol.224
, pp. 451-455
-
-
Hellman, U.1
Wernstedt, C.2
Gonez, J.3
-
14
-
-
0031690095
-
Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouse
-
Koshikawa N, Hasegawa S, Nagashima Y, et al. Expression of trypsin by epithelial cells of various tissues, leukocytes, and neurons in human and mouse. Am J Pathol 1998;153:937-44. (Pubitemid 28419046)
-
(1998)
American Journal of Pathology
, vol.153
, Issue.3
, pp. 937-944
-
-
Koshikawa, N.1
Hasegawa, S.2
Nagashima, Y.3
Mitsuhashi, K.4
Tsubota, Y.5
Miyata, S.6
Miyagi, Y.7
Yasumitsu, H.8
Miyazaki, K.9
-
15
-
-
33847342529
-
Role for protease activity in visceral pain in irritable bowel syndrome
-
DOI 10.1172/JCI29255
-
Cenac N, Andrews CN, Holzhausen M, et al. Role for protease activity in visceral pain in irritable bowel syndrome. J Clin Invest 2007;117:636-47. (Pubitemid 46348522)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.3
, pp. 636-647
-
-
Cenac, N.1
Andrews, C.N.2
Holzhausen, M.3
Chapman, K.4
Cottrell, G.5
Andrade-Gordon, P.6
Steinhoff, M.7
Barbara, G.8
Beck, P.9
Bunnett, N.W.10
Sharkey, K.A.11
Ferraz, J.G.P.12
Shaffer, E.13
Vergnolle, N.14
-
16
-
-
1842791710
-
Trypsin IV, a Novel Agonist of Protease-activated Receptors 2 and 4
-
DOI 10.1074/jbc.M312090200
-
Cottrell GS, Amadesi S, Grady EF, et al. Trypsin IV, a novel agonist of protease-activated receptors 2 and 4. J Biol Chem 2004;279:13532-9. (Pubitemid 38468878)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.14
, pp. 13532-13539
-
-
Cottrell, G.S.1
Amadesi, S.2
Grady, E.F.3
Bunnett, N.W.4
-
17
-
-
47649118832
-
Trypsinogen IV, serotonintransporter transcript levels and serotonin content are increased in small intestine of irritable bowel syndrome patients
-
KerckhoffsAP,TerLindeJJ,AkkermansLM, etal.TrypsinogenIV, serotonintransporter transcriptlevelsandserotonincontentareincreasedinsmallintestineofirritablebowel syndromepatients. NeurogastroenterolMotil 2008;20:900-7.
-
(2008)
NeurogastroenterolMotil
, vol.20
, pp. 900-907
-
-
Kerckhoffs, A.P.1
TerLinde, J.J.2
Akkermans, L.M.3
-
18
-
-
33846193703
-
Mast Cell-Dependent Excitation of Visceral-Nociceptive Sensory Neurons in Irritable Bowel Syndrome
-
DOI 10.1053/j.gastro.2006.11.039, PII S0016508506025194
-
Barbara G, Wang B, Stanghellini V, et al. Mast cell-dependent excitation of visceral-nociceptive sensory neurons in irritable bowel syndrome. Gastroenterology 2007;132:26-37. (Pubitemid 46108761)
-
(2007)
Gastroenterology
, vol.132
, Issue.1
, pp. 26-37
-
-
Barbara, G.1
Wang, B.2
Stanghellini, V.3
De Giorgio, R.4
Cremon, C.5
Di, N.G.6
Trevisani, M.7
Campi, B.8
Geppetti, P.9
Tonini, M.10
Bunnett, N.W.11
Grundy, D.12
Corinaldesi, R.13
-
19
-
-
70349423402
-
Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome
-
Buhner S, Li Q, Vignali S, et al . Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome. Gastroenterology 2009;137:1425-34.
-
(2009)
Gastroenterology
, vol.137
, pp. 1425-1434
-
-
Buhner, S.1
Li, Q.2
Vignali, S.3
-
20
-
-
77956102855
-
The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome
-
Klooker TK, Braak B, Koopman KE, et al. The mast cell stabiliser ketotifen decreases visceral hypersensitivity and improves intestinal symptoms in patients with irritable bowel syndrome. Gut 2010;59:1213-21.
-
(2010)
Gut
, vol.59
, pp. 1213-1221
-
-
Klooker, T.K.1
Braak, B.2
Koopman, K.E.3
-
21
-
-
0020581118
-
Determination of immunoreactive trypsin, pancreatic elastase and chymotrypsin in extracts of human feces and ileostomy drainage
-
Bohe M, Borgstrom A, Genell S, et al. Determination of immunoreactive trypsin, pancreatic elastase and chymotrypsin in extracts of human feces and ileostomy drainage. Digestion 1983;27:8-15. (Pubitemid 13066600)
-
(1983)
Digestion
, vol.27
, Issue.1
, pp. 8-15
-
-
Bohe, M.1
Borgstrom, A.2
Genell, S.3
Ohlsson, K.4
-
22
-
-
0017739636
-
Impaired enteric degradation of pancreatic endopeptidases in antibiotic-treated rats
-
Genell S, Gustafsson BE. Impaired enteric degradation of pancreatic endopeptidases in antibiotic-treated rats. Scand J Gastroenterol 1977;12:801-9. (Pubitemid 8226811)
-
(1977)
Scandinavian Journal of Gastroenterology
, vol.12
, Issue.7
, pp. 801-809
-
-
Genell, S.1
Gustafsson, B.E.2
-
23
-
-
0017391578
-
Elevated fecal levels of endogenous pancreatic endopeptidases after antibiotic treatment
-
Borgstrom A, Genell S, Ohlsson K. Elevated fecal levels of endogenous pancreatic endopeptidases after antibiotic treatment. Scand J Gastroenterol 1977;12:525 -9.
-
(1977)
Scand J Gastroenterol
, vol.12
, pp. 525-529
-
-
Borgstrom, A.1
Genell, S.2
Ohlsson, K.3
-
24
-
-
0034651865
-
Proteases in the evaluation of pancreatic function and pancreatic disease
-
DOI 10.1016/S0009-8981(99)00229-6, PII S0009898199002296
-
Goldberg DM. Proteases in the evaluation of pancreatic function and pancreatic disease. Clin Chim Acta 2000;291:201-21. (Pubitemid 30089765)
-
(2000)
Clinica Chimica Acta
, vol.291
, Issue.2
, pp. 201-221
-
-
Goldberg, D.M.1
-
25
-
-
0036840275
-
Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2
-
Cenac N, Coelho AM, Nguyen C, et al. Induction of intestinal inflammation in mouse by activation of proteinase-activated receptor-2. Am J Pathol 2002;161:1903-15. (Pubitemid 35265547)
-
(2002)
American Journal of Pathology
, vol.161
, Issue.5
, pp. 1903-1915
-
-
Cenac, N.1
Coelho, A.-M.2
Nguyen, C.3
Compton, S.4
Andrade-Gordon, P.5
MacNaughton, W.K.6
Wallace, J.L.7
Hollenberg, M.D.8
Bunnett, N.W.9
Garcia-Villar, R.10
Bueno, L.11
Vergnolle, N.12
-
26
-
-
11144310689
-
Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: Role of myosin light chain kinase
-
DOI 10.1016/j.pain.2004.10.002, PII S0304395904004804
-
It-Belgnaoui A, Bradesi S, Fioramonti J, et al. Acute stress-induced hypersensitivity to colonic distension depends upon increase in paracellular permeability: role of myosin light chain kinase. Pain 2005;113:141-7. (Pubitemid 40038455)
-
(2005)
Pain
, vol.113
, Issue.1-2
, pp. 141-147
-
-
Ait-Belgnaoui, A.1
Bradesi, S.2
Fioramonti, J.3
Theodorou, V.4
Bueno, L.5
-
28
-
-
70349799526
-
Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome
-
Zhou Q, Zhang B, Verne GN. Intestinal membrane permeability and hypersensitivity in the irritable bowel syndrome. Pain 2009;146:41-6.
-
(2009)
Pain
, vol.146
, pp. 41-46
-
-
Zhou, Q.1
Zhang, B.2
Verne, G.N.3
|