Dectin-1 activation induces proliferation and migration of human keratinocytes enhancing wound re-epithelialization

Cellular Immunology

Volumn 289, Issue 1-2, 2014, Pages 49-54

  van den Berg, Linda M ^a   Zijlstra Willems, Esther M ^a   Richters, Cornelia D ^b,d   Ulrich, Magda M W ^b,c   Geijtenbeek, Teunis B H ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ASSOCIATION OF DUTCH BURN CENTRES   (Netherlands)

^d Euro Skin Bank   (Netherlands)

Author keywords

Beta glucans; Dectin 1; Keratinocytes; Migration; Proliferation; Wound healing

Indexed keywords

CURDLAN; CYTOKINE; DECTIN 1;

ARTICLE; CELL ISOLATION; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIZATION; EX VIVO STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOSTIMULATION; IN VITRO STUDY; KERATINOCYTE; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SKIN CULTURE; WOUND CLOSURE; WOUND HEALING; WOUND REEPITHELIALIZATION;

BETA-GLUCANS; DECTIN-1; KERATINOCYTES; MIGRATION; PROLIFERATION; WOUND HEALING;

BETA-GLUCANS; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; HUMANS; KERATINOCYTES; LECTINS, C-TYPE; POLYSACCHARIDES, BACTERIAL; RE-EPITHELIALIZATION; SKIN;

EID: 84897938652     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2014.03.007     Document Type: Article

References (22)

1. Brown G.D., Gordon S. Immune recognition -A new receptor for beta-glucans. Nature 2001, 413:36-37.
2. Brown J., O'Callaghan C.A., Marshall A.S.J., Gilbert R.J.C., Siebold C., Gordon S., Brown G.D., Jones E.Y. Structure of the fungal beta-glucan-binding immune receptor dectin-1: Implications for function. Protein Sci. 2007, 16:1042-1052.
3. Coolen N.A., Vlig M., van den Bogaerdt A.J., Middelkoop E., Ulrich M.M. Development of an in vitro burn wound model. Wound Repair Regen. 2008, 16:559-567.
4. Davis S.C., Perez R. Cosmeceuticals and natural products: wound healing. Clin. Dermatol. 2009, 27:502-506.
5. de Koning H.D., Kamsteeg M., Rodijk-Olthuis D., van Vlijmen-Willems I.M., van Erp P.E., Schalkwijk J., Zeeuwen P.L. Epidermal expression of host response genes upon skin barrier disruption in normal skin and uninvolved skin of psoriasis and atopic dermatitis patients. J. Invest Dermatol. 2011, 131:263-266.
6. Delatte S.J., Evans J., Hebra A., Adamson W., Othersen H.B., Tagge E.P. Effectiveness of beta-glucan collagen for treatment of partial-thickness burns in children. J. Pediatr. Surg. 2001, 36:113-118.
7. Dennehy K.M., Ferwerda G., Faro-Trindade I., Pyz E., Willment J.A., Taylor P.R., Kerrigan A., Tsoni S.V., Gordon S., Meyer-Wentrup F., Adema G.J., Kullberg B.J., Schweighoffer E., Tybulewicz V., Mora-Montes H.M., Gow N.A.R., Williams D.L., Netea M.G., Brown G.D. Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors. Eur. J. Immunol. 2008, 38:500-506.
8. Gringhuis S.I., den Dunnen J., Litjens M., Hof B.V., van Kooyk Y., Geijtenbeek T.B.H. C-type lectin DC-SIGN modulates toll-like receptor signaling via Raf-1 kinase-dependent acetylation of transcription factor NF-kappa B. Immunity 2007, 26:605-616.
9. Gringhuis S.I., den Dunnen J., Litjens M., van der Vlist M., Geijtenbeek T.B.H. Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori. Nature Immunology 2009, 10:1081-1088.
10. Gringhuis S.I., den Dunnen J., Litjens M., van der Vlist M., Wevers B., Bruijns S.C.M., Geijtenbeek T.B.H. Dectin-1 directs T helper cell differentiation by controlling noncanonical NF-kappa B activation through Raf-1 and Syk. Nat. Immunol. 2009, 10:203-213.
11. Gross O., Gewies A., Finger K., Schafer M., Sparwasser T., Peschel C., Forster I., Ruland J. Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 2006, 442:651-656.
12. Hernanz-Falcon P., Arce I., Roda-Navarro P., Fernandez-Ruiz E. Cloning of human DECTIN-1, a novel C-type lectin-like receptor gene expressed on dendritic cells. Immunogenetics 2001, 53:288-295.
13. Kim H.L., Lee J.H., Lee M.H., Kwon B.J., Park J.C. Evaluation of Electrospun (1,3)-(1,6)-beta-D-Glucans/Biodegradable Polymer as Artificial Skin for Full-Thickness Wound Healing. Tissue Eng. Part A. 2012, 18:1-8.
14. Kobayashi M., Yoshiki R., Sakabe J., Kabashima K., Nakamura M., Tokura Y. Expression of toll-like receptor 2, NOD2 and dectin-1 and stimulatory effects of their ligands and histamine in normal human keratinocytes. Br. J. Dermatol. 2009, 160:297-304.
15. Kougias P., Wei D., Rice P.J., Ensley H.E., Kalbfleisch J., Williams D.L., Browder I.W. Normal human fibroblasts express pattern recognition receptors for fungal (1-3)-beta-D-glucans. Infect. Immun. 2001, 69:3933-3938.
16. Lee H.M., Shin D.M., Choi D.K., Lee Z.W., Kim K.H., Yuk J.M., Kim C.D., Lee J.H., Jo E.K. Innate immune responses to Mycobacterium ulcerans via toll-like receptors and dectin-1 in human keratinocytes. Cell. Microbiol. 2009, 11:678-692.
17. Lehtovaara B.C., Gu F.X. Pharmacological, Structural, and Drug Delivery Properties and Applications of 1,3-beta-Glucans. Journal of Agricultural. Food Chemistry 2011, 59:6813-6828.
18. LeibundGut-Landmann S., Gross O., Robinson M.J., Osorio F., Slack E.C., Tsoni S.V., Schweighoffer E., Tybulewicz V., Brown G.D., Ruland J. Reis e Sousa, Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat. Immunol. 2007, 8:630-638.
19. Ljungman A.G., Leanderson P., Tagesson C. (1-3)-beta-d-Glucan stimulates nitric oxide generation and cytokine mRNA expression in macrophages. Environ. Toxicol. Pharmacol. 1998, 5:273-281.
20. Martin P. Wound healing - Aiming for perfect skin regeneration. Science 1997, 276:75-81.
21. van den Berg L.M., De Jong M.A.W.P., de Witte L., Ulrich M.M.W., Geijtenbeek T.B.H. Burn injury suppresses human dermal dendritic cell and Langerhans cell function. Cell. Immunol. 2011, 268:29-36.
22. Willment J.A., Gordon S., Brown G.D. Characterization of the human beta -glucan receptor and its alternatively spliced isoforms. J. Biol. Chem. 2001, 276:43818-43823.