Neutrophil to lymphocyte ratio in relation to risk of all-cause mortality and cardiovascular events among patients undergoing angiography or cardiac revascularization: A meta-analysis of observational studies

Atherosclerosis

Volumn 234, Issue 1, 2014, Pages 206-213

  Wang, Xiaoding ^a   Zhang, Guangyu ^b   Jiang, Xuejun ^a   Zhu, Hongling ^a   Lu, Zhao ^a   Xu, Lin ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

All cause mortality; Cardiovascular events; Meta analysis; Neutrophil lymphocyte ratio

Indexed keywords

ANGIOGRAPHY; CARDIAC REVASCULARIZATION; CARDIOVASCULAR DISEASE; CARDIOVASCULAR MORTALITY; HEART SURGERY; HUMAN; LANGUAGE; LYMPHOCYTE COUNT; META ANALYSIS; MORTALITY; NEUTROPHIL COUNT; NEUTROPHIL TO LYMPHOCYTE RATIO; OUTCOME ASSESSMENT; PRIORITY JOURNAL; REVIEW; RISK FACTOR; SAMPLE SIZE; SENSITIVITY ANALYSIS; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; ANGIOCARDIOGRAPHY; BLOOD; CARDIOVASCULAR DISEASES; CAUSE OF DEATH; CORONARY ARTERY DISEASE; HEART MUSCLE REVASCULARIZATION; LEUKOCYTE COUNT; LYMPHOCYTE; NEUTROPHIL; OBSERVATIONAL STUDY; RADIOGRAPHY; RISK ASSESSMENT;

CARDIOVASCULAR DISEASES; CAUSE OF DEATH; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; HUMANS; LEUKOCYTE COUNT; LYMPHOCYTES; MYOCARDIAL REVASCULARIZATION; NEUTROPHILS; OBSERVATIONAL STUDY AS TOPIC; RISK ASSESSMENT;

EID: 84897937930     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2014.03.003     Document Type: Review

References (31)

1. Ross R. Atherosclerosis-an inflammatory disease. NEngl J Med 1999, 340(2):115-126.
2. Libby P., Ridker P.M., Hansson G.K. Leducq Transatlantic Network on atherothrombosis. Inflammation in atherosclerosis: from pathophysiology to practice. JAm Coll Cardiol 2009, 54(23):2129-2138.
3. Palmerini T., Marzocchi A., Marrozzini C., et al. Preprocedural levels of C-reactive protein and leukocyte counts predict 9-month mortality after coronary angioplasty for the treatment of unprotected left main coronary artery stenosis. Circulation 2005, 112(15):2332-2338.
4. Olenchock B.A., Wiviott S.D., Murphy S.A., et al. Lack of association between soluble CD40L and risk in large cohort of patients with acute coronary syndrome in OPUS TIMI-16. JThromb Thrombolysis 2008, 26(2):79-84.
5. Armstrong E.J., Morrow D.A., Sabatine M.S. Inflammatory biomarkers in acute coronary syndromes: part I: introduction and cytokines. Circulation 2006, 113(6):e72-e75.
6. Roman R.M., Camargo P.V., Borges F.K., Rossini A.P., Polanczyk C.A. Prognostic value of myeloperoxidase in coronary artery disease: comparison of unstable and stable angina patients. Coron Artery Dis 2010, 21(3):129-136.
7. Ferrante G., Nakano M., Prati F., et al. High levels of systemic myeloperoxidase are associated with coronaryplaque erosion in patients with acute coronary syndromes: a clinicopathological study. Circulation 2010, 122(24):2505-2513.
8. Gurm H.S., Bhatt D.L., Gupta R., Ellis S.G., Topol E.J., Lauer M.S. Preprocedural white blood cell count and death after percutaneous coronary intervention. Am Heart J 2003, 146(4):692-698.
9. Prasad A., Stone G.W., Stuckey T.D., et al. Relation between leucocyte count, myonecrosis, myocardial perfusion, and outcomes following primary angioplasty. Am J Cardiol 2007, 99(8):1067-1071.
10. Fowler A.J., Agha R.A. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography-The growing versatility of NLR. Atherosclerosis 2013, 228(1):44-45.
11. Poludasu S., Cavusoglu E., Khan W., Marmur J.D. Neutrophil to lymphocyte ratio as a predictor of long-term mortality in African Americans undergoing percutaneous coronary intervention. Clin Cardiol 2009, 32(12):E6-E10.
12. Shen X.H., Chen Q., Shi Y., Li H.W. Association of neutrophil/lymphocyte ratio with long-term mortality after ST elevation myocardial infarction treated with primary percutaneous coronary intervention. Chin Med J 2010, 123(23):3438-3443.
13. Park J.J., Jang H.J., Oh I.Y., et al. Prognostic value of neutrophil to lymphocyte ratio in patients presenting with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention. Am J Cardiol 2013, 111(5):636-642.
14. Soylu K., Yuksel S., Gulel O., et al. The relationship of coronary flow to neutrophil/lymphocyte ratio in patients undergoing primary percutaneous coronary intervention. JThorac Dis 2013, 5(3):258-264.
15. Sen N., Afsar B., Ozcan F., et al. The neutrophil to lymphocyte ratio was associated with impaired myocardial perfusion and long term adverse outcome in patients with ST-elevated myocardial infarction undergoing primary coronary intervention. Atherosclerosis 2013, 228(1):203-210.
16. Núñez J., Núñez E., Bodí V., et al. Usefulness of the neutrophil to lymphocyte ratio in predicting long-term mortality in ST segment elevation myocardial infarction. Am J Cardiol 2008, 101(6):747-752.
17. Han Y.C., Yang T.H., Kim D.I., et al. Neutrophil to lymphocyte ratio predicts long-term clinical outcomes in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Korean Circ J 2013, 43(2):93-99.
18. Gibson P.H., Croal B.L., Cuthbertson B.H., et al. Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting. Am Heart J 2007, 154(5):995-1002.
19. Guasti L., Dentali F., Castiglioni L., et al. Neutrophils and clinical outcomes in patients with acute coronary syndromes and/or cardiac revascularisation. A systematic review on more than 34,000 subjects. Thromb Haemost 2011, 106(4):591-599.
20. Stroup D.F., Berlin J.A., Morton S.C., et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (MOOSE) group. JAMA 2000, 283(15):2008-2012.
21. Higgins J.P., Thompson S.G., Deeks J.J., Altman D.G. Measuring inconsistency in meta-analyses. BMJ 2003, 327(7414):557-560.
22. ó Hartaigh B., Bosch J.A., Thomas G.N., et al. Which leukocyte subsets predict cardiovascular mortality? from the LUdwigshafen RIsk and Cardiovascular Health (LURIC) Study. Atherosclerosis 2012, 224(1):161-169.
23. Arbel Y., Finkelstein A., Halkin A., et al. Neutrophil/lymphocyte ratio is related to the severity of coronary artery disease and clinical outcome in patients undergoing angiography. Atherosclerosis 2012, 225(2):456-460.
24. Tamhane U.U., Aneja S., Montgomery D., Rogers E.K., Eagle K.A., Gurm H.S. Association between admission neutrophil to lymphocyte ratio and outcomes in patients with acute coronary syndrome. Am J Cardiol 2008, 102(6):653-657.
25. Zernecke A., Bot I., Djalali-Talab Y., et al. Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis. Circ Res 2008, 102(2):209-217.
26. Weber C., Zernecke A., Libby P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat Rev Immunol 2008, 8(10):802-815.
27. Azab B., Zaher M., Weiserbs K.F., et al. Usefulness of neutrophil to lymphocyte ratio in predicting short- and long-term mortality after non-ST-elevation myocardial infarcton. Am J Cardiol 2010, 106(4):470-476.
28. Hotchkiss R.S., Karl I.E. The pathophysiology and treatment of sepsis. NEngl J Med 2003, 348(2):138-150.
29. Bhutta H., Agha R., Wong J., Tang T.Y., Wilson Y.G., Walsh S.R. Neutrophil lymphocyte ratio predicts medium-term survival following elective major vascular surgery: a cross-sectional study. Vasc Endovasc Surg 2011, 45(3):227-231.
30. Ommen S.R., Gibbons R.J., Hodge D.O., Thomson S.P. Usefulness of the lymphocyte concentration as a prognostic marker in coronary artery disease. Am J Cardiol 1997, 79(6):812-814.
31. Blum A., Sclarovsky S., Rehavia E., Shohat B. Levels of T-lymphocyte subpopulations, interleukin-1 beta, and soluble interleukin-2 receptor in acute myocardial infarction. Am Heart J 1994, 127(5):1226-1230.