Comparative haematological parameters of HbAA and HbAS genotype children infected with Plasmodium falciparum malaria in Yemen

Hematology

Volumn 19, Issue 3, 2014, Pages 169-174

  Albiti, Anisa H ^a   Nsiah, Kwabena ^b  

^a Al Gamhouria Teaching Hospital   (Yemen)

^b KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Ghana)

Author keywords

Children; Falciparum malaria; Haematological parameters; Sickle cell; Yemen

Indexed keywords

FERRITIN; HEMOGLOBIN A; HEMOGLOBIN S; IRON; HEMOGLOBIN; HEMOGLOBIN AA; HEMOGLOBIN AS;

ANEMIA; ARTICLE; CHILD; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; GENOTYPE; GRANULOCYTE; HEMATOCRIT; HUMAN; LEUKOCYTE; LYMPHOCYTE; MALARIA FALCIPARUM; MALE; MONOCYTE; PARASITE TRANSMISSION; PARASITEMIA; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; RETICULOCYTE COUNT; SPECTROPHOTOMETRY; THROMBOCYTE COUNT; BLOOD; COMPARATIVE STUDY; GENETICS; HOST PARASITE INTERACTION; LEUKOCYTE COUNT; METABOLISM; PARASITOLOGY; PHYSIOLOGY; PLASMODIUM FALCIPARUM; SICKLE CELL TRAIT; YEMEN;

BLOOD SEDIMENTATION; CHILD; CHILD, PRESCHOOL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FERRITINS; GENOTYPE; HEMATOCRIT; HEMOGLOBIN A; HEMOGLOBIN, SICKLE; HEMOGLOBINS; HOST-PARASITE INTERACTIONS; HUMANS; IRON; LEUKOCYTE COUNT; MALARIA, FALCIPARUM; MALE; PARASITEMIA; PLASMODIUM FALCIPARUM; PLATELET COUNT; RETICULOCYTE COUNT; SICKLE CELL TRAIT; YEMEN;

EID: 84897908418     PISSN: 10245332     EISSN: 16078454     Source Type: Journal    
DOI: 10.1179/1607845413Y.0000000113     Document Type: Article

References (38)

1. WHO. WHO Global Malaria Program. World malaria report. Geneva: World Health Organization; 2010.
2. Price RN, Simpson JA, Nosten F, Luxemburger C, Hkirjaroen L, ter Kuile F, et al. Factors contributing to anemia after uncomplicated falciparum malaria. Am J Trop Med Hyg. 2001;65: 614-22.
3. Aidoo M, Terlouw DJ, Kolczak MS, McElroy PD, ter Kuile FO, Kariuki S, et al. Protective effects of the sickle cell gene against malaria morbidity and mortality. Lancet 2002;359:1311-2.
4. Williams TN, Mwangi TW, Wambua S, Alexander ND, Kortok M, Snow RW, et al. Sickle cell trait and the risk of Plasmodium falciparum malaria and other childhood diseases. J Infect Dis. 2005;192:178-86.
5. Cooke G, Hill A. Genetic of susceptibility to human infectious disease. Nat Rev Genet. 2001;2:967-77.
6. McElroy PD, Lal AA, Hawley WA, Bloland PB, Kuile FO, Oloo AJ, et al. Analysis of repeated hemoglobin measures in full-term, normal birth weight Kenyan children between birth and four years of age. III: The Asembo Bay cohort project. Am J Trop Med Hyg. 1999;61:932-40.
7. WHO. Manual of basic techniques for a health laboratory. 2nd ed. Geneva: World Health Organization; 2003.
8. WHO. Nutritional anaemias: report of aWHOScientific Group. Geneva: World Health Organization; 1968. Technical Report Series, No. 405. Available from: http://whqlibdoc.who.int/trs/ WHO_TRS_405.pdf
9. Nkuo-Akenji T, Wepngong P, Akoachere J. Effects of ABO/Rh blood group, G-6-P-D enzyme activity and haemoglobin genotypes on malaria parasitaemia and parasite density. Afr J Health Sci. 2004;11:93-7.
10. Makani J, Komba AN, Cox SE, Oruo J, Mwamtemi K, Kitundu J, et al. Malaria in patients with sickle cell anemia: burden, risk factors, and outcome at the outpatient clinic and during hospitalization. Blood 2010;115:215-20.
11. Friedman MJ. Erythrocytic mechanism of sickle cell resistance to malaria. Proc Natl Acad Sci USA. 1978;75:1994-7.
12. Pasvol G, Weatherall DJ, Wilson RJ. Cellular mechanisms for the protective effect of haemoglobin S against P. falciparum malaria. Nature 1978;274:701-3.
13. Luzzatto L, Nwachuku-Jarrett ES, Reddy S. Increased sickling of parasitized erythrocytes as mechanism of resistance against malaria in the sickle-cell trait. Lancet 1970;1:319-21.
14. Roth EF, Jr, Friedman M, Ueda Y, Tellez I, Trager W, Nagel RL. Sickling rates of human AS red cells infected in vitro with Plasmodium falciparum malaria. Science 1978;202:650-2.
15. Friedman MJ, Roth EF, Nagel RL, Trager W. Plasmodium falciparum: physiological interactions with the human sickle cell. Exp Parasitol. 1979;47:73-80.
16. Hebbel RP. Sickle hemoglobin instability: a mechanism for malaria protection. Redox Rep. 2003;8:238-40.
17. Ayi K, Turrini F, Piga A, Arese P. Enhanced phagocytosis of ring parasitized mutant erythrocytes: a common mechanism that may explain protection against falciparum-malaria in sickle-trait and beta thalassemia-trait. Blood 2004;104:3364-71.
18. Abu-Zeid YA, Abdulhadi NH, Theander TG, Hviid L, Saeed BO, Jepsen S, et al. Seasonal changes in cell mediated immune responses to soluble Plasmodium falciparum antigens in children with haemoglobin AA and haemoglobin AS. Trans R Soc Trop Med Hyg. 1992;86:20-2.
19. Le Hesran JY, Personne I, Personne P, Fievet N, Dubois B, Beyemé M, et al. Longitudinal study of Plasmodium falciparum infection and immune responses in infants with or without the sickle cell trait. Int Jo Epidemiol. 1999;28:793-8.
20. Roberts DJ, Casals-Pascual C, Weatherall DJ. The clinical, pathophysiological features of malarial anaemia. Current Topics in Microbiology and Immunol. 2005;295:137-67.
21. Barnwell JW. Malaria: death and disappearing erythrocytes. Blood 2006;107:854-6.
22. Casals-Pascual C, Kai O, Newton CR, Peshu N, Roberts DJ. Thrombocytopenia in falciparum malaria is associated with high concentrations of IL-10. Am J Trop Med Hyg. 2006;75: 434-6.
23. Abdalla SH. Peripheral blood and bone marrow leucocytes in Gambian children with malaria: numerical changes and evaluation of phagocytosis. Ann Trop Pediatr. 1988;8:250-8.
24. Reiley CG, Barrett O, Jr. Leukocyte response in acute malaria. Am J Med Sci. 1971;262:153-8.
25. Ladhani S, Lowe B, Cole AO, Kowuondo K, Newton CR. Changes in white blood cells and platelets in children with falciparum malaria: relationship to disease outcome. Brit J Haematol. 2002;119:839-47.
26. Nielson H, Theander TG. Blood monocyte oxidative burst activity in acute P. falciparum malaria. Acta Pathol Microbiol Immunol Scand. 1989;97:469-71.
27. Tebo AE, Kremsner PG, Luty AJ. Plasmodium falciparum: a major role for IgG3 in antibody-dependent monocyte-mediated cellular inhibition of parasite growth in vitro. Exp Parasitol. 2001;98:20-8.
28. Dale DC, Wolf SM. Studies of the neutropenia of acute malaria. Blood 1973;41:197-206.
29. Gérardin P, Rogier C, Ka AS, Jouvencel P, Brousse V, Imbert P. Prognostic value of thrombocytopenia in African children with falciparum malaria. Am J Trop Med Hyg. 2002;66:686-91.
30. Skudowitz RB, Katz J, Lurie A, Levin J, Metz J. Mechanisms of thrombocytopenia in malignant tertian malaria. Brit Med J. 1973;2:515-8.
31. Essien EM. The circulating platelet in acute malaria infection. Brit J Haematol. 1989;72:589-90.
32. Eriksson B, Hellgren U, Rombo L. Changes in erythrocyte sedimentation rate, C-reactive protein and hematological parameters in patients with acute malaria. Scand J Infect Dis. 1989;21:434-41.
33. Stoltzfus RJ, Chwaya HM, Albonico M, Schulze KJ, Savioli L, Tielsch JM. Serum ferritin, erythrocyte protoporphyrin and hemoglobin are valid indicators of iron status of school children with malaria in a malaria holoendemic population. J Nutr. 1997; 127:293-8.
34. de Mast Q, Nadjm B, Reyburn H, Kemna EH, Amos B, Laarakkers CM, et al. Assessment of urinary concentrations of hepcidin provides novel insight into disturbances in iron homeostasis during malarial infection. J Inf Dis. 2009;199: 253-62.
35. Weiss G. Iron metabolism in the anemia of chronic disease. Biochim BiophysActa. 2008;1790:682-93.
36. Menendez C, Todd J, Alonso PL, Francis N, Lulat S, Ceesay S, et al. The response to iron supplementation of pregnant women with the haemoglobin genotype AA or AS. Trans R Soc Trop Med Hyg. 1995;89:289-99.
37. Jeremiah ZA, Uko EK, Usanga EA. Relation of nutritional status, Sickle cell trait, glucose-6-phosphate dehydrogenase deficiency, iron deficiency and asymptomatic malaria infection in the Niger Delta, Nigeria. J Med Sci. 2008;8:269-74.
38. OtienoW, Estambale BBA, Aluoch JR, Gondi SMO, Stoute JA. Association between sickle cell trait and low density parasitaemia in a Plasmodium falciparum holoendemic region of western Kenya. Intl J Trop Dis Health. 2012;2:231-40