No overall damage progression despite persistent inflammation in adalimumab-treated psoriatic arthritis patients: Results from an investigator-initiated 48-week comparative magnetic resonance imaging, computed tomography and radiography trial

Rheumatology (United Kingdom)

Volumn 53, Issue 4, 2014, Pages 746-756

  Poggenborg, René Panduro ^a,b   Wiell, Charlotte ^a   Bøyesen, Pernille ^c   Boonen, Annelies ^d   Bird, Paul ^e   Pedersen, Susanne Juhl ^f   Sørensen, Inge Juul ^a   Madsen, Ole Rintek ^f   Slot, Ole ^a   Møller, Jakob M ^f   Hasselquist, Maria ^f   Kubassova, Olga ^g   østergaard, Mikkel ^a,b  

^a Mental Health Center Glostrup   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c DIAKONHJEMMET HOSPITAL   (Norway)

^d MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^e UNIVERSITY OF NEW SOUTH WALES   (Australia)

^f GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^g Image Analysis Ltd   (United Kingdom)

Author keywords

Biologic therapy; Computed tomography; Magnetic resonance imaging; Psoriatic arthritis; Radiography

Indexed keywords

ADALIMUMAB;

ADULT; ARTICLE; BONE EROSION; BONE MARROW EDEMA; BONE RADIOGRAPHY; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COMPUTER ASSISTED TOMOGRAPHY; CONTRAST ENHANCEMENT; DISEASE ACTIVITY; DISEASE COURSE; DISEASE DURATION; FEMALE; FOLLOW UP; HUMAN; INTERMETHOD COMPARISON; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OPEN STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSORIATIC ARTHRITIS; SYNOVITIS; TENOSYNOVITIS;

BIOLOGIC THERAPY; COMPUTED TOMOGRAPHY; MAGNETIC RESONANCE IMAGING; PSORIATIC ARTHRITIS; RADIOGRAPHY;

ADULT; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL, HUMANIZED; ARTHRITIS, PSORIATIC; DISEASE-FREE SURVIVAL; FEMALE; HAND JOINTS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SYNOVITIS; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME;

EID: 84897893917     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ket426     Document Type: Article

References (30)

1. Eder L, Chandran V, Gladman DD. Repair of radiographic joint damage following treatment with etanercept in psoriatic arthritis is demonstrable by 3 radiographic methods. J Rheumatol 2011;38:1066-70.
2. Dohn UM, Ejbjerg B, Boonen A et al. No overall progression and occasional repair of erosions despite persistent inflammation in adalimumab-treated rheumatoid arthritis patients: results from a longitudinal comparative MRI, ultrasonography, CT and radiography study. Ann Rheum Dis 2011;70:252-8.
3. Ostergaard M, McQueen F, Wiell C et al. The OMERACT psoriatic arthritis magnetic resonance imaging scoring system (PsAMRIS): definitions of key pathologies, suggested MRI sequences, and preliminary scoring system for PsA hands. J Rheumatol 2009;36:1816-24.
4. Boyesen P, McQueen FM, Gandjbakhch F et al. The OMERACT Psoriatic Arthritis Magnetic Resonance Imaging Score (PsAMRIS) is reliable and sensitive to change: results from an OMERACT workshop. J Rheumatol 2011;38:2034-8.
5. Perry D, Stewart N, Benton N et al. Detection of erosions in the rheumatoid hand a comparative study of multidetector computerized tomography versus magnetic resonance scanning. J Rheumatol 2005;32:256-67.
6. Dohn UM, Ejbjerg BJ, Court-Payen et al. Are bone erosions detected by magnetic resonance imaging and ultrasonography true erosions? A comparison with computed tomography in rheumatoid arthritis metacarpophalangeal joints. Arthritis Res Ther 2006;8:R110.
7. Taylor W, Gladman D, Helliwell P et al. Classification criteria for psoriatic arthritis: development of new criteria from a large international study. Arthritis Rheum 2006;54:2665-73.
8. World Medical Association. WMA Declaration of Helsinki. http://www.wma.net/en/30publications/10policies/b3/ index.html (13 December 2013, date last accessed).
9. Thorsen H, Hansen TM, McKenna SP et al. Adaptation into Danish of the Stanford Health Assessment Questionnaire (HAQ) and the Rheumatoid Arthritis Quality of Life Scale (RAQoL). Scand J Rheumatol 2001;30:103-109.
10. Clegg DO, Reda DJ, Mejias E et al. Comparison of sulfasalazine and placebo in the treatment of psoriatic arthritis. A Department of Veterans Affairs Cooperative Study. Arthritis Rheum 1996;39:2013-20.
11. FitzGerald O, Helliwell P, Mease P et al. Application of composite disease activity scores in psoriatic arthritis to the PRESTA data set. Ann Rheum Dis 2012;71:358-62.
12. Kubassova O, Boesen M, Boyle RD et al. Fast and robust analysis of dynamic contrast enhanced MRI datasets. Med Image Comput Comput Assist Interv 2007;10(Pt 2):261-9.
13. Boesen M, Ostergaard M, Cimmino MA et al. MRI quantification of rheumatoid arthritis: current knowledge and future perspectives. Eur J Radiol 2009;71:189-96.
14. Axelsen MB, Stoltenberg M, Poggenborg RP et al. Dynamic gadolinium-enhanced magnetic resonance imaging allows accurate assessment of the synovial inflammatory activity in rheumatoid arthritis knee joints: a comparison with synovial histology. Scand J Rheumatol 2012;41:89-94.
15. van der Heijde D, Sharp J, Wassenberg S et al. Psoriatic arthritis imaging: a review of scoring methods. Ann Rheum Dis 2005;64(Suppl 2):ii61-4.
16. Wassenberg S, Fischer-Kahle V, Herborn G et al. A method to score radiographic change in psoriatic arthritis. Z Rheumatol 2001;60:156-66.
17. Husted JA, Cook RJ, Farewell VT et al. Methods for assessing responsiveness: a critical review and recommendations. J Clin Epidemiol 2000;53:459-68.
18. Anandarajah AP, Ory P, Salonen D et al. Effect of adalimumab on joint disease: features of patients with psoriatic arthritis detected by magnetic resonance imaging. Ann Rheum Dis 2010;69:206-9.
19. Cimmino MA, Barbieri F, Boesen M et al. Dynamic contrast- enhanced magnetic resonance imaging of articular and extraarticular synovial structures of the hands in patients with psoriatic arthritis. J Rheumatol Suppl 2012;89:44-8.
20. Axelsen M, Poggenborg R, Stoltenberg M et al. Reliability and responsiveness of dynamic contrast-enhanced magnetic resonance imaging in rheumatoid arthritis. Scand J Rheumatol 2013;42:115-22.
21. Boesen M, Kubassova O, Bouert R et al. Correlation between computer-aided dynamic gadolinium-enhanced MRI assessment of inflammation and semi-quantitative synovitis and bone marrow oedema scores of the wrist in patients with rheumatoid arthritis-a cohort study. Rheumatology 2012;51:134-43.
22. Jimenez-Boj E, Nobauer-Huhmann I, Hanslik-Schnabel B et al. Bone erosions and bone marrow edema as defined by magnetic resonance imaging reflect true bone marrow inflammation in rheumatoid arthritis. Arthritis Rheum 2007;56:1118-24.
23. McQueen FM, Gao A, Ostergaard M et al. High-grade MRI bone oedema is common within the surgical field in rheumatoid arthritis patients undergoing joint replacement and is associated with osteitis in subchondral bone. Ann Rheum Dis 2007;66:1581-7.
24. Haavardsholm EA, Boyesen P, Ostergaard M et al. Magnetic resonance imaging findings in 84 patients with early rheumatoid arthritis: bone marrow oedema predicts erosive progression. Ann Rheum Dis 2008;67:794-800.
25. Hetland ML, Ejbjerg B, Horslev-Petersen K et al. MRI bone oedema is the strongest predictor of subsequent radiographic progression in early rheumatoid arthritis. Results from a 2-year randomised controlled trial (CIMESTRA). Ann Rheum Dis 2009;68:384-90.
26. Tan YM, Ostergaard M, Doyle A et al. MRI bone oedema scores are higher in the arthritis mutilans form of psoriatic arthritis and correlate with high radiographic scores for joint damage. Arthritis Res Ther 2009;11:R2.
27. Gladman DD, Mease PJ, Choy EH et al. Risk factors for radiographic progression in psoriatic arthritis: subanalysis of the randomized controlled trial ADEPT. Arthritis Res Ther 2010;12:R113.
28. Poddubnyy D, Rudwaleit M. Efficacy and safety of adalimumab treatment in patients with rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis. Expert Opin Drug Saf 2011;10:655-73.
29. Mease PJ, Gladman DD, Ritchlin CT et al. Adalimumab for the treatment of patients with moderately to severely active psoriatic arthritis: results of a double-blind, randomized, placebo-controlled trial. Arthritis Rheum 2005;52:3279-89.
30. Dohn UM, Ejbjerg BJ, Hasselquist M et al. Rheumatoid arthritis bone erosion volumes on CT and MRI: reliability and correlations with erosion scores on CT, MRI and radiography. Ann Rheum Dis 2007;66:1388-92.