Association of race/ethnicity, inflammation, and albuminuria in patients with diabetes and early chronic kidney disease

Diabetes Care

Volumn 37, Issue 4, 2014, Pages 1060-1068

  Sinha, Satyesh K ^a   Shaheen, Magda ^a   Rajavashisth, Tripathi B ^a,b   Pan, Deyu ^a   Norris, Keith C ^a,b   Nicholas, Susanne B ^a,b  

^a CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; ANGIOTENSIN RECEPTOR ANTAGONIST; C REACTIVE PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; HEMOGLOBIN A1C; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METFORMIN; PIOGLITAZONE; URIC ACID;

ADULT; AFRICAN AMERICAN; ALBUMINURIA; ARTICLE; CARDIOVASCULAR DISEASE; CAUCASIAN; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE DURATION; ETHNIC DIFFERENCE; FEMALE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HISPANIC; HUMAN; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PREVALENCE; RACE DIFFERENCE; AGED; ANCESTRY GROUP; CHRONIC KIDNEY FAILURE; COMPLICATION; ETHNIC GROUP; ETHNOLOGY; MIDDLE AGED; NUTRITION; PATHOPHYSIOLOGY; YOUNG ADULT;

ADULT; AGED; ALBUMINURIA; CONTINENTAL POPULATION GROUPS; DIABETES COMPLICATIONS; ETHNIC GROUPS; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; NUTRITION SURVEYS; YOUNG ADULT;

EID: 84897867289     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc13-0013     Document Type: Article

References (40)

1. U.S. Renal Data System. National Institutes of Health. Bethesda, MD, National Institute of Diabetes and Digestive and Kidney Diseases, 2012
2. Carter JS, Pugh JA, Monterrosa A. Non-insulin-dependent diabetes mellitus in minorities in the United States. Ann Intern Med 1996;125:221-232 (Pubitemid 126449266)
3. Tarver-Carr ME, Powe NR, Eberhardt MS, et al. Excess risk of chronic kidney disease among African-American versus white subjects in the United States: a population-based study of potential explanatory factors. J Am Soc Nephrol 2002;13:2363-2370 (Pubitemid 34925247)
4. Hsu CY, Lin F, Vittinghoff E, Shlipak MG. Racial differences in the progression from chronic renal insuf ficiency to end-stage renal disease in the United States. J Am Soc Nephrol 2003;14:2902-2907 (Pubitemid 37305653)
5. Young BA, Maynard C, Boyko EJ. Racial differences in diabetic nephropathy, cardiovascular disease, and mortality in a national population of veterans. Diabetes Care 2003;26:2392-2399 (Pubitemid 36993332)
6. Erlinger TP, Tarver-Carr ME, Powe NR, et al. Leukocytosis, hypoalbuminemia, and the risk for chronic kidney disease in US adults. Am J Kidney Dis 2003;42:256-263 (Pubitemid 36944432)
7. Fried L, Solomon C, Shlipak M, et al. Inflammatory and prothrombotic markers and the progression of renal disease in elderly individuals. J Am Soc Nephrol 2004;15:3184-3191 (Pubitemid 39578851)
8. Tuttle KR. Linking metabolism and immunology: diabetic nephropathy is an inflammatory disease. J Am Soc Nephrol 2005;16:1537-1538 (Pubitemid 41716459)
9. Mora C, Navarro JF. Inflammation and diabetic nephropathy. Curr Diab Rep 2006;6:463-468 (Pubitemid 44896406)
10. Navarro JF, Mora C, Maca M, Garca J. Inflammatory parameters are independently associated with urinary albumin in type 2 diabetes mellitus. Am J Kidney Dis 2003;42:53-61 (Pubitemid 36807654)
11. Fox ER, Benjamin EJ, Sarpong DF, et al. The relation of C-reactive protein to chronic kidney disease in African Americans: the Jackson Heart Study. BMC Nephrol 2010;11:1-7
12. Kshirsagar AV, Bomback AS, Bang H, et al. Association of C-reactive protein and microalbuminuria (from the National Health and Nutrition Examination Surveys, 1999 to 2004). Am J Cardiol 2008;101:401-406 (Pubitemid 351175628)
13. Sabanayagam C, Lee J, Shankar A, Lim SC, Wong TY, Tai ES. C-reactive protein and microalbuminuria in a multi-ethnic Asian population. Nephrol Dial Transplant 2010;25:1167-1172
14. Niewczas MA, Ficociello LH, Johnson AC, et al. Serum concentrations of markers of TNFalpha and Fas-mediated pathways and renal function in nonproteinuric patients with type 1 diabetes. Clin J Am Soc Nephrol 2009;4:62-70
15. Wolkow PP, Niewczas MA, Perkins B, et al. Association of urinary inflammatory markers and renal decline in microalbuminuric type 1 diabetics. J Am Soc Nephrol 2008;19:789-797
16. Slopen N, Lewis TT, Gruenewald TL, et al. Early life adversity and in flammation in African Americans and whites in the midlife in the United States survey. Psychosom Med 2010;72:694-701
17. Bryson CL, Ross HJ, Boyko EJ, Young BA. Racial and ethnic variations in albuminuria in the US Third National Health and Nutrition Examination Survey (NHANES III) population: associations with diabetes and level of CKD. Am J Kidney Dis 2006;48:720-726 (Pubitemid 44740045)
18. Jolly SE, Burrows NR, Chen SC, et al. Racial and ethnic differences in albuminuria in individuals with estimated GFR greater than 60 mL/min/1.73 m(2): results from the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis 2010;55(Suppl. 2):S15-S22
19. Festa A, D'Agostino R, Howard G, Mykkänen L, Tracy RP, Haffner SM. In flammation and microalbuminuria in nondiabetic and type 2 diabetic subjects: The Insulin Resistance Atherosclerosis Study. Kidney Int 2000;58:1703-1710
20. Palmas W, Ma S, Jacobs DR Jr, et al. Ethnicity and sex modify the association of serum c-reactive protein with microalbuminuria. Ethn Dis 2008;18:324-329
21. Noori N, Kovesdy CP, Dukkipati R, et al. Racial and ethnic differences in mortality of hemodialysis patients: role of dietary and nutritional status and inflammation. Am J Nephrol 2011;33:157-167
22. Crews DC, Sozio SM, Liu Y, Coresh J, Powe NR. Inflammation and the paradox of racial differences in dialysis survival. J Am Soc Nephrol 2011;22:2279-2286
23. Chen J, Wildman RP, Hamm LL, et al.; Third National Health and Nutrition Examination Survey. Association between inflammation and insulin resistance in U.S. nondiabetic adults: results from the Third National Health and Nutrition Examination Survey. Diabetes Care 2004;27:2960-2965 (Pubitemid 39565066)
24. Jalal DI, Maahs DM, Hovind P, Nakagawa T. Uric acid as a mediator of diabetic nephropathy. Semin Nephrol 2011;31:459-465
25. Sautin YY, Johnson RJ. Uric acid: the oxidant-antioxidant paradox. Nucleosides Nucleotides Nucleic Acids 2008;27:608-619 (Pubitemid 351948591)
26. Navarro-González JF, Mora-Fernández C. The role of inflammatory cytokines in diabetic nephropathy. J Am Soc Nephrol 2008;19:433-442 (Pubitemid 351355386)
27. Dalla Vestra M, Mussap M, Gallina P, et al. Acute-phase markers of inflammation and glomerular structure in patients with type 2 diabetes. J Am Soc Nephrol 2005;16(Suppl. 1):S78-S82 (Pubitemid 41725090)
28. Banba N, Nakamura T, Matsumura M, Kuroda H, Hattori Y, Kasai K. Possible relationship of monocyte chemoattractant protein-1 with diabetic nephropathy. Kidney Int 2000;58:684-690 (Pubitemid 30620017)
29. Liu F, Chen HY, Huang XR, et al. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes. Diabetologia 2011;54:2713-2723
30. Wang HR, Chen DL, Zhao M, et al. C-reactive protein induces interleukin-6 and thrombospondin-1 protein and mRNA expression through activation of nuclear factor-κB in HK-2 cells. Kidney Blood Press Res 2012;35:211-219
31. Verma S, Li SH, Badiwala MV, et al. Endothelin antagonism and interleukin-6 inhibition attenuate the proatherogenic effects of C-reactive protein. Circulation 2002;105:1890-1896 (Pubitemid 34437614)
32. Horii Y, Iwano M, Hirata E, et al. Role of interleukin-6 in the progression of mesangial proliferative glomerulonephritis. Kidney Int Suppl 1993;39:S71-S75
33. Kaplan M, Tendler Y, Mahamid R, Shiner M, Aviram M, Hayek T. High glucose upregulates C-reactive protein synthesis in macrophages. Clin Chem 2010;56:1036-1038
34. Devaraj S, Jialal I. C-reactive protein polarizes human macrophages to an M1 phenotype and inhibits transformation to the M2 phenotype. Arterioscler Thromb Vasc Biol 2011;31:1397-1402
35. Devaraj S, Yun J-M, Duncan-Staley C, Jialal I. C-reactive protein induces M-CSF release and macrophage proliferation. J Leukoc Biol 2009;85:262-267
36. Nguyen D, Ping F, Mu W, Hill P, Atkins RC, Chadban SJ. Macrophage accumulation in human progressive diabetic nephropathy. Nephrology (Carlton) 2006;11:226-231
37. Mourad JJ, Pannier B, Blacher J, et al. Creatinine clearance, pulse wave velocity, carotid compliance and essential hypertension. Kidney Int 2001;59:1834-1841 (Pubitemid 32336798)
38. Pergola PE, Raskin P, Toto RD, et al.; BEAM Study Investigators. Bardoxolone methyl and kidney function in CKD with type 2 diabetes. N Engl J Med 2011;365:327-336
39. Loftus P, Weaver C. Abbott Says Study of Kidney-Disease Drug Is Stopped. Wall Street Journal, 18 October 2012. Available from http://online.wsj.com/ article/SB10000872396390443684104578064460504033202.html. Accessed 29 March 2013
40. Zoja C, Corna D, Nava V, et al. Analogues of bardoxolone methyl worsen diabetic nephropathy in rats with additional adverse effects. Am J Physiol Renal Physiol 2013;304:F808-F819