Associations between selected allergens, phthalates, nicotine, polycyclic aromatic hydrocarbons, and bedroom ventilation and clinically confirmed asthma, rhinoconjunctivitis, and atopic dermatitis in preschool children

Indoor Air

Volumn 24, Issue 2, 2014, Pages 136-147

  Callesen, M ^a   Beko G ^b   Weschler, C J ^b,c   Sigsgaard, T ^d   Jensen, T K ^e   Clausen, G ^b   Toftum, J ^b   Norberg, L A ^f   Host A ^a  

^a ODENSE UNIVERSITY HOSPITAL   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY   (United States)

^d AARHUS UNIVERSITY   (Denmark)

^e UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^f Odense City Government and Administration   (Denmark)

Author keywords

Allergic diseases; Clinical examination; Dust mites; Pet allergens; Specific IgE

Indexed keywords

ALLERGENS; DIAGNOSIS; DISEASE CONTROL; DUST; NICOTINE; POLYCYCLIC AROMATIC HYDROCARBONS;

AIR CHANGES; ALLERGIC DISEASE; ATOPIC DERMATITIS; CLINICAL EXAMINATION; CONTROL GROUPS; DUST MITE; DUST SAMPLES; HEALTHY CONTROLS; PET ALLERGEN; SPECIFIC IGE;

ESTERS;

ALLERGEN; DUST; NICOTINE; PHTHALIC ACID DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON;

AIR CONDITIONING; ANALYSIS; CASE CONTROL STUDY; CHEMICALLY INDUCED; DENMARK; DUST; HUMAN; HYPERSENSITIVITY, IMMEDIATE; IMMUNOLOGY; INDOOR AIR POLLUTION; PET ANIMAL; PRESCHOOL CHILD;

AIR POLLUTION, INDOOR; ALLERGENS; CASE-CONTROL STUDIES; CHILD, PRESCHOOL; DENMARK; DUST; HUMANS; HYPERSENSITIVITY, IMMEDIATE; NICOTINE; PETS; PHTHALIC ACIDS; POLYCYCLIC HYDROCARBONS, AROMATIC; VENTILATION;

EID: 84897842483     PISSN: 09056947     EISSN: 16000668     Source Type: Journal    
DOI: 10.1111/ina.12060     Document Type: Article

References (59)

1. Asher, I., Baena-Cagnani, C., Boner, A., Canonica, G.W., Chuchalin, A., Custovic, A., Dagli, E., Haahtela, T., Haus, M., Lemmo-Hoten, M., Holgate, S., Holloway, J., Holt, P., Host, A., Iikura, Y., Johansson, S.G., Kaplan, A., Kowalski, M.L., Lockey, R.F., Naspitz, C., Odhiambo, J., Ring, J., Sastre, J., Venables, K., Vichyanond, P., Volovitz, B., Wahn, U., Warner, J., Weiss, K., Zhong, N.S. and World Allergy Organization. (2004) World Allergy Organization guidelines for prevention of allergy and allergic asthma, Int. Arch. Allergy Immunol., 135, 83-92.
2. Bekö, G., Lund, T., Nors, F., Toftum, J.R. and Clausen, G. (2010) Ventilation rates in the bedrooms of 500 Danish children, Build. Environ., 45, 2289-2295.
3. Bornehag, C.G., Sundell, J., Weschler, C.J., Sigsgaard, T., Lundgren, B., Hasselgren, M. and Hagerhed-Engman, L. (2004) The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study, Environ. Health Perspect., 112, 1393-1397.
4. Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A., Zuberbier, T., Baena-Cagnani, C.E., Canonica, G.W., Van Weel, C., Agache, I., Ait-Khaled, N., Bachert, C., Blaiss, M.S., Bonini, S., Boulet, L.P., Bousquet, P.J., Camargos, P., Carlsen, K.H., Chen, Y., Custovic, A., Dahl, R., Demoly, P., Douagui, H., Durham, S.R., Van Wijk, R.G., Kalayci, O., Kaliner, M.A., Kim, Y.Y., Kowalski, M.L., Kuna, P., Le, L.T., Lemiere, C., Li, J., Lockey, R.F., Mavale-Manuel, S., Meltzer, E.O., Mohammad, Y., Mullol, J., Naclerio, R., O'Hehir, R.E., Ohta, K., Ouedraogo, S., Palkonen, S., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T.A., Rabe, K.F., Rosado-Pinto, J., Scadding, G.K., Simons, F.E., Toskala, E., Valovirta, E., Van Cauwenberge, P., Wang, D.Y., Wickman, M., Yawn, B.P., Yorgancioglu, A., Yusuf, O.M., Zar, H., Annesi-Maesano, I., Bateman, E.D., Ben Kheder, A., Boakye, D.A., Bouchard, J., Burney, P., Busse, W.W., Chan-Yeung, M., Chavannes, N.H., Chuchalin, A., Dolen, W.K., Emuzyte, R., Grouse, L., Humbert, M., Jackson, C., Johnston, S.L., Keith, P.K., Kemp, J.P., Klossek, J.M., Larenas-Linnemann, D., Lipworth, B., Malo, J.L., Marshall, G.D., Naspitz, C., Nekam, K., Niggemann, B., Nizankowska-Mogilnicka, E., Okamoto, Y., Orru, M.P., Potter, P., Price, D., Stoloff, S.W., Vandenplas, O., Viegi, G. and Williams, D. (2008) Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen), Allergy, 63(Suppl. 86), 8-160.
5. Brussee, J.E., Smit, H.A., Van Strien, R.T., Corver, K., Kerkhof, M., Wijga, A.H., Aalberse, R.C., Postma, D., Gerritsen, J., Grobbee, D.E., de Jongste, J.C. and Brunekreef, B. (2005) Allergen exposure in infancy and the development of sensitization, wheeze, and asthma at 4 years, J. Allergy Clin. Immunol., 115, 946-952.
6. Chen, C.M., Tischer, C., Schnappinger, M. and Heinrich, J. (2010) The role of cats and dogs in asthma and allergy - a systematic review, Int. J. Hyg. Environ. Health, 213, 1-31.
7. Clausen, G., Host, A., Toftum, J., Bekö, G., Weschler, C., Callesen, M., Buhl, S., Ladegaard, M.B., Langer, S., Andersen, B., Sundell, J., Bornehag, C.G. and Sigsgaard, T. (2012) Children's health and its association with indoor environments in Danish homes and daycare centres - methods, Indoor Air, 22, 467-475.
8. Cook, D.G. and Strachan, D.P. (1997) Health effects of passive smoking. 3. Parental smoking and prevalence of respiratory symptoms and asthma in school age children, Thorax, 52, 1081-1094.
9. Custovic, A., Hallam, C.L., Simpson, B.M., Craven, M., Simpson, A. and Woodcock, A. (2001) Decreased prevalence of sensitization to cats with high exposure to cat allergen, J. Allergy Clin. Immunol., 108, 537-539.
10. De Blay, F., Chapman, M.D. and Platts-Mills, T.A. (1991) Airborne cat allergen (Fel d I). Environmental control with the cat in situ, Am. Rev. Respir. Dis., 143, 1334-1339.
11. Earle, C.D., King, E.M., Tsay, A., Pittman, K., Saric, B., Vailes, L., Godbout, R., Oliver, K.G. and Chapman, M.D. (2007) High-throughput fluorescent multiplex array for indoor allergen exposure assessment, J. Allergy Clin. Immunol., 119, 428-433.
12. Eggleston, P.A. (2005) Improving indoor environments: reducing allergen exposures, J. Allergy Clin. Immunol., 116, 122-126.
13. Eick, S.A. and Richardson, G. (2011) Investigation of different approaches to reduce allergens in asthmatic children's homes-the Breath of Fresh Air Project, Cornwall, United Kingdom, Sci. Total Environ., 409, 3628-3633.
14. Eigenmann, P.A., Atanaskovic-Markovic, M., O'B Hourihane, J., Lack, G., Lau, S., Matricardi, P.M., Muraro, A., Namazova Baranova, L., Nieto, A., Papadopoulos, N.G., Réthy, L.A., Roberts, G., Rudzeviciene, O., Wahn, U., Wickman, M. and Høst, A. (2013) Pediatr. Allergy Immunol., 24, 195-209.
15. Gehring, U., Wijga, A.H., Brauer, M., Fischer, P., de Jongste, J.C., Kerkhof, M., Oldenwening, M., Smit, H.A. and Brunekreef, B. (2010) Traffic-related air pollution and the development of asthma and allergies during the first 8 years of life, Am. J. Respir. Crit. Care Med., 181, 596-603.
16. Gold, D.R. (2000) Environmental tobacco smoke, indoor allergens, and childhood asthma, Environ. Health Perspect., 108(Suppl. 4), 643-651.
17. Hagerhed-Engman, L.H., Bornehag, C.-G. and Sundell, J. (2007) How valid are parents' questionnaire responses regarding building characteristics, mouldy odour, and signs of moisture problems in Swedish homes? Scand. J. Public Health, 35, 125-132.
18. Hagerhed-Engman, L., Sigsgaard, T., Samuelson, I., Sundell, J., Janson, S. and Bornehag, C.G. (2009) Low home ventilation rate in combination with moldy odor from the building structure increase the risk for allergic symptoms in children, Indoor Air, 19, 184-192.
19. Halken, S. (2004) Prevention of allergic disease in childhood: clinical and epidemiological aspects of primary and secondary allergy prevention, Pediatr. Allergy Immunol., 15(Suppl. 16), 4-5, 9-32.
20. Hanifin, J.M. and Rajka, G. (1980) Diagnostic features of atopic dermatitis, Acta Derm. Venereol., 59(Suppl. 92), 44-47.
21. Harving, H. and Korsgaard, J. (1994) Clinical efficacy of reduction in house-dust mite exposure in specially designed, mechanically ventilated healthy homes, Allergy, 49, 866-870.
22. Harving, H., Korsgaard, J. and Dahl, R. (1993) House-dust mites and associated environmental-conditions in Danish homes, Allergy, 48, 106-109.
23. Harving, H., Korsgaard, J. and Dahl, R. (1994) House-dust mite exposure reduction in specially designed, mechanically ventilated "healthy" homes, Allergy, 49, 713-718.
24. Heinrich, J. (2011) Influence of indoor factors in dwellings on the development of childhood asthma, Int. J. Hyg. Environ. Health, 214, 1-25.
25. Heissenhuber, A., Heinrich, J., Fahlbusch, B., Borte, M., Wichmann, H.E. and Bolte, G. (2003) Health impacts of second-hand exposure to cat allergen Fel d 1 in infants, Allergy, 58, 154-157.
26. Host, A., Halken, S., Muraro, A., Dreborg, S., Niggemann, B., Aalberse, R., Arshad, S.H., Von Berg, A., Carlsen, K.H., Duschen, K., Eigenmann, P.A., Hill, D., Jones, C., Mellon, M., Oldeus, G., Oranje, A., Pascual, C., Prescott, S., Sampson, H., Svartengren, M., Wahn, U., Warner, J.A., Warner, J.O., Vandenplas, Y., Wickman, M. and Zeiger, R.S. (2008) Dietary prevention of allergic diseases in infants and small children, Pediatr. Allergy Immunol., 19, 1-4.
27. Hsu, N.Y., Lee, C.C., Wang, J.Y., Li, Y.C., Chang, H.W., Chen, C.Y., Bornehag, C.G., Wu, P.C., Sundell, J. and Su, H.J. (2012) Predicted risk of childhood allergy, asthma and reported symptoms using measured phthalate exposure in dust and urine, Indoor Air, 22, 186-199.
28. Institute of Medicine, U.S. (2004) Damp Indoor Spaces and Health, Committee on Damp Indoor Spaces and Health, Washington, D.C., National Academies Press.
29. Jaakkola, J.J. and Knight, T.L. (2008) The role of exposure to phthalates from polyvinyl chloride products in the development of asthma and allergies: a systematic review and meta-analysis, Environ. Health Perspect., 116, 845-853.
30. Jaakkola, J.J.K., Oie, L., Nafstad, P., Botten, G., Samuelsen, S.O. and Magnus, P. (1999) Interior surface materials in the home and the development of bronchial obstruction in young children in Oslo, Norway, Am. J. Public Health, 89, 188-192.
31. Jaakkola, J.J.K., Verkasalo, P.A. and Jaakkola, N. (2000) Plastic wall materials in the home and respiratory health in young children, Am. J. Public Health, 90, 797-799.
32. Jaakkola, J.J.K., Parise, H., Lebedeva, N.I. and Spengler, J.D. (2004) Asthma, wheezing and allergies in Russian schoolchildren in relation to new surface materials in the home, Am. J. Public Health, 94, 560-562.
33. Jerrett, M., Shankardass, K., Berhane, K., Gauderman, W.J., Künzli, N., Avol, E., Gilliland, F., Lurmann, F., Molitor, J.N., Molitor, J.T., Thomas, D.C., Peters, J. and McConnell, R. (2008) Traffic-related air pollution and asthma onset in children: a prospective cohort study with individual exposure measurement, Environ. Health Perspect., 116, 1433-1438.
34. Johnke, H., Vach, W., Norberg, L.A., Bindslev-Jensen, C., Host, A. and Andersen, K.E. (2005) A comparison between criteria for diagnosing atopic eczema in infants, Br. J. Dermatol., 153, 352-358.
35. Kim, S., Aung, T., Berkeley, E., Diette, G.B. and Breysse, P.N. (2008) Measurement of nicotine in household dust, Environ. Res., 108, 289-293.
36. Kolarik, B., Naydenov, K., Larsson, M., Bornehag, C.G. and Sundell, J. (2008) The association between phthalates in dust and allergic diseases among Bulgarian children, Environ. Health Perspect., 116, 98-103.
37. Langer, S., Weschler, C.J., Fischer, A., Bekö, G., Toftum, J.R. and Clausen, G. (2010) Phthalate and PAH concentrations in dust collected from Danish homes and daycare centers, Atmos. Environ., 44, 2294-2301.
38. McConnell, R., Berhane, K., Yao, L., Jerrett, M., Lurmann, F., Gilliland, F., Ki, N., Gauderman, J., Avol, E., Thomas, D. and Peters, J.M. (2006) Traffic, susceptibility, and childhood asthma, Environ. Health Perspect., 114, 766-772.
39. McCreanor, J., Cullinan, P., Nieuwenhuijsen, M.J., Stewart-Evans, J., Malliarou, E., Jarup, L., Harrington, R., Svartengren, M., Han, I.-K., Ohman-Strickland, P., Chung, K.F. and Zhang, J. (2007) Respiratory effects of exposure to diesel traffic in persons with asthma, N. Engl. J. Med., 357, 2348-2358.
40. Muraro, A., Dreborg, S., Halken, S., Host, A., Niggemann, B., Aalberse, R., Arshad, S.H., Von Berg, A., Carlsen, K.H., Duschen, K., Eigenmann, P., Hill, D., Jones, C., Mellon, M., Oldeus, G., Oranje, A., Pascual, C., Prescott, S., Sampson, H., Svartengren, M., Vandenplas, Y., Wahn, U., Warner, J.A., Warner, J.O., Wickman, M. and Zeiger, R.S. (2004) Dietary prevention of allergic diseases in infants and small children. Part II. Evaluation of methods in allergy prevention studies and sensitization markers. Definitions and diagnostic criteria of allergic diseases, Pediatr. Allergy Immunol., 15, 196-205.
41. Naydenov, K., Melikov, A., Markov, D., Stankov, P., Bornehag, C.G. and Sundell, J. (2008) A comparison between occupants' and inspectors' reports on home dampness and their association with the health of children: the ALLHOME study, Build. Environ., 43, 1840-1849.
42. Niggemann, B., Jacobsen, L., Dreborg, S., Ferdousi, H.A., Halken, S., Host, A., Koivikko, A., Koller, D., Norberg, L.A., Urbanek, R., Valovirta, E., Wahn, U. and Moller, C. (2006) Five-year follow-up on the PAT study: specific immunotherapy and long-term prevention of asthma in children, Allergy, 61, 855-859.
43. Oda, J., Nomura, S., Yasuhara, A. and Shibamoto, T. (2001) Mobile sources of atmospheric polycyclic aromatic hydrocarbons in a roadway tunnel, Atmos. Environ., 35, 4819-4827.
44. Øie, L., Hersoug, L.G. and Madsen, J.Ø. (1997) Residential exposure to plasticizers and its possible role in the pathogenesis of asthma, Environ. Health Perspect., 105, 972-978.
45. Øie, L., Nafstad, P., Botten, G. and Jaakkola, J.J.K. (1999) Ventilation in the homes and bronchial obstruction in young children, Epidemiology, 110, 294-299.
46. Pietinalho, A., Pelkonen, A. and Rytila, P. (2009) Linkage between smoking and asthma, Allergy, 64, 1722-1727.
47. Platts-Mills, T., Vaughan, J., Squillace, S., Woodfolk, J. and Sporik, R. (2001) Sensitization, asthma, and a modified Th2 response in children exposed to cat allergen: a population-based cross-sectional study, Lancet, 357, 752-756.
48. Rothe, M.J. and Grant-Kels, J.M. (1996) Diagnostic criteria for atopic dermatitis, Lancet, 348, 769-770.
49. Salam, M.T., Islam, T. and Gilliland, F.D. (2008) Recent evidence for adverse effects of residential proximity to traffic sources on asthma, Curr. Opin. Pulm. Med., 14, 3-8.
50. Soto-Martinez, M.E., Avila, L. and Soto-Quiros, M.E. (2009) New criteria for the diagnosis and management of asthma in children under 5 years old: GINA Guidelines 2009, An. Pediatr. (Barc), 71, 91-94.
51. Spaan, S., Doekes, G., Heederik, D., Thorne, P.S. and Wouters, I.M. (2008) Effect of extraction and assay media on analysis of airborne endotoxin, Appl. Environ. Microbiol., 74, 3804-3811.
52. Strachan, D.P. (1988) Damp housing and childhood asthma: validation of reporting of symptoms, BMJ, 297, 1223-1226.
53. Takaro, T.K., Krieger, J., Song, L., Sharify, D. and Beaudet, N. (2011) The Breathe-Easy Home: the impact of asthma-friendly home construction on clinical outcomes and trigger exposure, Am. J. Public Health, 101, 55-62.
54. Tovey, E. and Marks, G. (1999) Methods and effectiveness of environmental control, J. Allergy Clin. Immunol., 103, 179-191.
55. Weschler, C.J., Langer, S., Fisher, A., Bekö, G., Toftum, J. and Clausen, G. (2011) Nicotine in dust samples collected from children's bedrooms and daycare centers in Denmark. In: Proceedings of Indoor Air 2011, Austin, Texas, USA, Abstract No. 326.
56. Whitehead, T., Metayer, C., Ward, M.H., Nishioka, M.G., Gunier, R., Colt, J.S., Reynolds, P., Selvin, S., Buffler, P. and Rappaport, S.M. (2009) Is house-dust nicotine a good surrogate for household smoking? Am. J. Epidemiol., 169, 1113-1123.
57. Wickman, M., Egmar, A., Emenius, G., Almqvist, C., Berglind, N., Larsson, P. and Van Hage-Hamsten, M. (1999) Fel d 1 and Can f 1 in settled dust and airborne Fel d 1 in allergen avoidance day-care centres for atopic children in relation to number of pet-owners, ventilation and general cleaning, Clin. Exp. Allergy, 29, 626-632.
58. Wright, G.R., Howieson, S., McSharry, C., McMahon, A.D., Chaudhuri, R., Thompson, J., Donnelly, I., Brooks, R.G., Lawson, A., Jolly, L., McAlpine, L., King, E.M., Chapman, M.D., Wood, S. and Thomson, N.C. (2009) Effect of improved home ventilation on asthma control and house dust mite allergen levels, Allergy, 64, 1671-1680.
59. Zmirou, D., Gauvin, S., Pin, I., Momas, I., Sahraoui, F., Just, J., Le Moullec, Y., Brémont, F., Cassadou, S., Reungoat, P., Albertini, M., Lauvergne, N., Chiron, M. and Labbé, A. (2004) Traffic related air pollution and incidence of childhood asthma: results of the Vesta case-control study, J. Epidemiol. Community Health, 58, 18-23.