Topical delivery of vitamin D3: A randomized controlled pilot study

International Journal of Biomedical Science

Volumn 10, Issue 1, 2014, Pages 21-24

  Sadat Ali, Mir ^a   Bubshait, Dalal A ^a   Al Turki, Haifa A ^a   Al Dakheel, Dakheel A ^a   Al Olayani, Wissam S ^a  

^a IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY   (Saudi Arabia)

Author keywords

Deficiency; Medication burden; Route of administration; Vitamin D

Indexed keywords

CALCIFEDIOL; PENETRATION ENHANCING AGENT; PLACEBO; TOP D; UNCLASSIFIED DRUG; VITAMIN D;

ADULT; AGE; ALOE VERA; ARTICLE; BLOOD SAMPLING; BODY HEIGHT; BODY MASS; BODY WEIGHT; CLINICAL EXAMINATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; FEMALE; HUMAN; HUMAN EXPERIMENT; MEDICAL HISTORY; MEDICAL STUDENT; NORMAL HUMAN; PILOT STUDY; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL;

EID: 84897833228     PISSN: 15509702     EISSN: 15552810     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Whistler D. Morbo puerili Anglorum, quem patrio idiomate indigenae vocant. Lugduni Batavorum: The Rickets. 1645; p1-13.
2. Glisson F. De Rachitide sive morbo puerili, qui vulgo. London: The Rickets diciteur. 1650; p1-416.
3. Hernigou P. Historical overview of rickets, osteomalacia, and vitamin D. Rev. Rhum. Engl. Ed.1995 Apr; 62 (4): 261-270.
4. Mellanby E. Experimental rickets. Medical Research (G.B.), Special Report Series. 1921; SRS-61: 1-78.
5. Sedrani SH, Elidrissy AW, El Arabi KM. Sunlight and vitamin D status in normal Saudi subjects. Am. J. Clin. Nutr. 1983 Jul; 38 (1): 129-132.
6. Sedrani SH. Low 25-hydroxyvitamin D and normal serum calcium concentrations in Saudi Arabia: Riyadh region. Ann. Nutr. Metab. 1984; 28 (3): 181-185.
7. Al-Turki HA, Sadat-Ali M, Al-Elq AH, Al-Mulhim FA, et al. 25-Hydoxyvitamin D levels among healthy Saudi Arabian women. Saudi Med. J. 2008 Dec; 29 (12): 1765-1768.
8. Sadat-Ali M, AlElq A, Al-Turki H, Al-Mulhim F, et al. Vitamin D levels in healthy men in eastern Saudi Arabia. Ann. Saudi Med. 2009 Sep-Oct; 29 (5): 378-382.
9. ElSammak MY, Al-Wossaibi AA, Al-Howeish A, Alsaeed J. Vitamin D deficiency in Saudi Arabs. Horm. Metab. Res. 2010; 42: 1-5.
10. Al-Elq AM. The status of Vitamin D in medical students in the preclerkship years of a Saudi medical school. J. Family Community Med. 2012 May; 19 (2): 100-104.
11. Grant AM, Avenell A, Campbell MK, et al. RECORD Trial Group. Oral vitamin D3 and calcium for secondary prevention of low-trauma fractures in elderly people (Randomised Evaluation of Calcium Or vitamin D, RECORD): a randomized placebo-controlled trial. Lancet. 2005; 365: 1621-1628.
12. Porthouse J, Cockayne S, King C, et al. Randomised controlled trial of calcium and supplementation with cholecalciferol (vitamin D3) for prevention of fractures in primary care. Br. Med. J. 2005; 330: 1003-1006.
13. Jackson RD, LaCroix AZ, Gass M, et al. for the Women's Health Initiative Investigators. Calcium plus vitamin D supplementation and the risk of fractures. N. Engl. J. Med. 2006; 354: 669-683.
14. Avorn, J. Medications and the Elderly. In Rowe J. and Besdine R, eds. Geriatric Medicine, 2d ed. Boston: Little, Brown. 1988.
15. Kruse W, Koch-Gwinner P, Nikolaus T, Oster P, et al. Measurement of Drug Compliance by Continuous Electronic Monitoring: A Pilot Study in Elderly Patients Discharged from Hospital. Journal of the American Geriatrics Society. 1992; 40: 1151-1155.
16. Nikolaus T, Kruse W, Bach M, Specht-Leible N, et al. Elderly Patients' Problems with Medication. An In-Hospital and Follow-Up Study. European Journal of Clinical Pharmacology. 1996; 49 (4): 255-259.
17. Thomas BJ, Finnin BC. The transdermal revolution. Drug Discov. Today. 2004; 9: 697-703.
18. Shi Y, Wei Z, Zhao H, Liu T, et al. Electrospinning of ibuprofen-loaded composite nanofibers for improving the performances of transdermal patches. J. Nanosci. Nanotechnol. 2013 Jun; 13 (6): 3855-3863.
19. Plaza-Villegas F, Heir G, Markman S, Khan J, et al. Topical pregabalin and diclofenac for the treatment of neuropathic orofacial pain in rats. Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. 2012 Oct; 114 (4): 449-456.
20. Derry S, Moore RA. Topical capsaicin (low concentration) for chronic neuropathic pain in adults. Cochrane Database Syst Rev. 2012 Sep 12; 9: CD010111. doi: 10.1002/14651858.CD010111.
21. Aggarwal N, Goindi S. Preparation and in vivo evaluation of solid lipid nanoparticles of griseofulvin for dermal use. J. Biomed. Nanotechnol. 2013 Apr; 9 (4): 564-576.
22. Ahad A, Al-Jenoobi FI, Al-Mohizea AM, Aqil M, et al. Transdermal delivery of calcium channel blockers for hypertension. Expert Opin. Drug. Deliv. 2013 Aug; 10 (8): 1137-1153.
23. Goodman MP. Are all estrogens created equal? A review of oral vs. transdermal therapy. J. Womens Health (Larchmt). 2012 Feb; 21 (2): 161-169.
24. Morrow DIJ, McCarron PA, Woolfson AD, Donnelly RF. Innovative Strategies for Enhancing Topical and Transdermal Drug Delivery. The Open Drug Delivery Journal. 2007; p36-59
25. Williams AC. Transdermal and topical drug delivery. London: Pharmaceutical Press. 2003.
26. nd ed. New York: Marcel Dekker. 1989.
27. Segal E, Zinman C, Raz B, Ish-Shalom S. Low patient compliance--a major negative factor in achieving vitamin D adequacy in elderly hip fracture patients supplemented with 800IU of vitamin D3 daily. Arch. Gerontol Geriatr. 2009 Nov-Dec; 49 (3): 364-367.
28. Castelo-Branco C, Cortés X, Ferrer M. Treatment persistence and compliance with a combination of calcium and vitamin D. Climacteric. 2010 Dec; 13 (6): 578-584.
29. Anfelix-Genovés J, Gil-Guillén VF, Orozco-Beltran D, Giner-Ruiz V, et al. Determinant factors of osteoporosis patients' reported therapeutic adherence to calcium and/or vitamin D supplements: a cross-sectional, observational study of postmenopausal women. Drugs Aging. 2009; 26 (10): 861-869.
30. Díez A, Carbonell C, Calaf J, Caloto MT, et al. Observational study of treatment compliance in women initiating antiresorptive therapy with or without calcium and vitamin D supplements in Spain. Menopause. 2012 Jan; 19 (1): 89-95.