Bacteremic pneumococcal pneumonia: Serotype distribution, antimicrobial susceptibility, severity scores, risk factors, and mortality in a single center in Chile

Brazilian Journal of Infectious Diseases

Volumn 18, Issue 2, 2014, Pages 115-123

  Fica, Alberto ^a   Bunster, Nicolás ^a   Aliaga, Felipe ^a   Olivares, Felipe ^a   Porte, Lorena ^a   Braun, Stephanie ^a   Dabanch, Jeannette ^a   Hormázabal, Juan Carlos ^b   Hernández, Antonio ^a   Benavides, María Guacolda ^a  

^a HOSPITAL MILITAR DE SANTIAGO   (Chile)

^b INSTITUTO DE SALUD PÚBLICA DE CHILE   (Chile)

Author keywords

APACHE II; Bacteremia; CURB 65; Elderly; Microbial drug resistance; Mortality; PIRO; Risk factors; Serotyping; Streptococcus pneumoniae

Indexed keywords

AMOXICILLIN; CEFOTAXIME; LEVOFLOXACIN; PENICILLIN DERIVATIVE; VANCOMYCIN;

ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; CHILE; COMMUNITY ACQUIRED PNEUMONIA; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HUMAN; IMMUNIZATION; INFLUENZA; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MORTALITY; NONHUMAN; PROGNOSIS; RISK FACTOR; SEASONAL VARIATION; SEROTYPE; STREPTOCOCCUS PNEUMONIA; THROMBOCYTE COUNT; VERY ELDERLY; AGE; ALCOHOLISM; APACHE; BACTEREMIC PNEUMOCOCCAL PNEUMONIA; CAP PIRO SEVERITY SCORE; COMORBIDITY; CORTICOSTEROID THERAPY; CURB 65 SEVERITY SCORE; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE PREDISPOSITION; DISEASE SEVERITY ASSESSMENT; FATALITY; HOSPITAL ADMISSION; INFECTION RISK; INFLUENZA VACCINATION; INTENSIVE CARE; LENGTH OF STAY; PENICILLIN RESISTANCE; PNEUMOCOCCAL IMMUNIZATION; PREDICTIVE VALUE; RETROSPECTIVE STUDY; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SMOKING; STREPTOCOCCUS PNEUMONIAE; VACCINATION;

APACHE II; BACTEREMIA; CURB-65; ELDERLY; MICROBIAL DRUG RESISTANCE; MORTALITY; PIRO; RISK FACTORS; SEROTYPING; STREPTOCOCCUS PNEUMONIAE;

ADULT; AGED; AGED, 80 AND OVER; ANTI-BACTERIAL AGENTS; BACTEREMIA; CHILE; COMMUNITY-ACQUIRED INFECTIONS; EPIDEMIOLOGIC METHODS; FEMALE; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; PNEUMONIA, PNEUMOCOCCAL; SEASONS; STREPTOCOCCUS PNEUMONIAE; YOUNG ADULT;

EID: 84897611974     PISSN: 14138670     EISSN: 16784391     Source Type: Journal    
DOI: 10.1016/j.bjid.2013.06.001     Document Type: Article

References (39)

1. Rosselli D., Rueda J.D. Burden of pneumococcal infection in adults in Colombia. J Infect Public Health 2012, 5:354-359.
2. Wroe P.C., Finkelstein J.A., Ray G.T., et al. Aging population and future burden of pneumococcal pneumonia in the United States. J Infect Dis 2012, 205:1589-1592.
3. Rioseco M.L., Riquelme R. Bacteremic pneumococcal pneumonia in 45 immunocompromised hospitalized adults. Rev Med Chile 2004, 132:588-594.
4. Saldías F., Viviani P., Pulgar D., Valenzuela F., Paredes S., Díaz O. Prognostic factors and mortality in immunocompetent adult patients hospitalized with community-acquired pneumococcal pneumonia. Rev Med Chile 2009, 137:1545-1552.
5. Palma I., Mosquera R., Demier C., Vay C.A., Famiglietti A., Luna C.M. Impact of bacteremia in a cohort of patients with pneumococcal pneumonia. J Bras Pneumol 2012, 38:422-430.
6. Menéndez R., Sahuquillo-Arce J.M., Reyes S., et al. Cytokine activation patterns and biomarkers are influenced by microorganisms in community-acquired pneumonia. Chest 2012, 141:1537-1545.
7. Neuman M.I., Kelley M., Harper M.B., File T.M., Camargo C.A. Factors associated with antimicrobial resistance and mortality in pneumococcal bacteremia. J Emerg Med 2007, 32:349-357. EMNet Investigators.
8. Zemlicková H., Crisóstomo M.I., Brandileone M.C., et al. Serotypes and clonal types of penicillin-susceptible Streptococcus pneumoniae causing invasive disease in children in five Latin American countries. Microb Drug Resist 2005, 11:195-204.
9. Castañeda E., Agudelo C.I., De Antonio R., Rosselli D., Calderón C., Ortega-Barria E., Colindres R.E. Streptococcus pneumoniae serotype 19A in Latin America and the Caribbean: a systematic review and meta-analysis, 1990-2010. BMC Infect Dis 2012, 12:124.
10. Rello J., Rodriguez A., Lisboa T., Gallego M., Lujan M., Wunderink R. PIRO score for community-acquired pneumonia: a new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia. Crit Care Med 2009, 37:456-462.
11. Lim W.S., van der Eerden M.M., Laing R., et al. Defining community acquired pneumonia severity on presentation at hospital: an international derivation and validation study. Thorax 2003, 58:377-382.
12. Kim P.E., Musher D.M., Glezen W.P., Rodriguez-Barrada M.C., Nahm W.K., Wright C.E. Association of invasive pneumococcal disease with season, atmospheric conditions, air pollution, and the isolation of respiratory viruses. Clin Infect Dis 1996, 22:100-106.
13. Proyecto vigilancia virus respiratorios. Available at. http://www.virus.med.puc.cl/virus_respiratorios/.
14. Departamento de Estadísticas e información de Salud. Ten leader causes of death in Chile in elderly patients. Available at:. http://www.deis.cl/estadisticas-mortalidad/.
15. Ministerio del Medio ambiente, Chile. Chapter 1 Air Pollution. Available at. http://www.mma.gob.cl/1304/w3-article-52016.html.
16. Thigpen M.C., Whitney C.G., Messonnier N.E., et al. Bacterial meningitis in the United States, 1998-2007. N Eng J Med 2011, 364:2016-2025.
17. Lin S.H., Lai C.C., Tan C.K., Liao W.H., Hsueh P.R. Outcomes of hospitalized patients with bacteraemic and non-bacteraemic community-acquired pneumonia caused by Streptococcus pneumonia. Epidemiol Infect 2011, 139:1307-1316.
18. Bordon J., Peyrani P., Brock G.N., et al. The presence of pneumococcal bacteremia does not influence clinical outcomes in patients with community-acquired pneumonia: results from the Community-Acquired Pneumonia Organization (CAPO) International Cohort study. Chest 2008, 133:618-624.
19. Alanee S.R.J., McGee L., Jackson D., et al. Association of serotypes of Streptococcus pneumonia with disease severity and outcome in adults: an international study. Clin Infect Dis 2007, 45:46-51.
20. Christensen J.S., Jensen T.G., Kolmos H.J., Pedersen C., Lassen A. Bacteremia with Streptococcus pneumoniae: sepsis and other risk factors for 30-day mortality-a hospital-based cohort study. Eur J Clin Microbiol Infect Dis 2012, 31:2719-2725.
21. Imran M.N., Leng P.H., Yang S., Kurup A., Eng P. Early predictors of mortality in pneumococcal bacteremia. Ann Acad Med Singapore 2005, 34:426-431.
22. Barahona Rondón L., Soriano García F., Granizo Martínez J.J., Santos ÓConnor F., López Durán J.C., Fernández Roblas R. Risk factor of mortality in invasive pneumococcal disease. Med Clin (Barc) 2004, 123:575-577.
23. Martens P., Worm S.W., Lundgren B., Konradsen H.B., Benfield T. Serotype-specific mortality from invasive Streptococcus pneumoniae disease revisited. BMC Infect Dis 2004, 4:21.
24. Lujan M., Gallego M., Fontanals D., Mariscal D., Rello J. Prospective observational study of bacteremic pneumococcal pneumonia: effect of discordant therapy on mortality. Crit Care Med 2004, 32:625-631.
25. Watanakunakorn C., Bailey T.A. Adult bacteremic pneumococcal pneumonia in a community teaching hospital, 1992-1996. A detailed analysis of 108 cases. Arch Intern Med 1997, 157:1965-1971.
26. Armstrong M., Fica A., Dabanch J., Olivares F., Fasce R., Triantafilo V. Morbidity and mortality associated to influenza A (H1N1) 2009 admissions in two hospitals of the Metropolitan area and analysis of its economic impact. Rev Chilena Infectol 2012, 29:664-671.
27. Saldías F., Díaz O. Severity scores for predicting clinically relevant outcomes for immunocompetent adult patients hospitalized with community-acquired pneumococcal pneumonia. Rev Chilena Infectol 2011, 28:303-309.
28. Confalonieri M., Urbino R., Potena A., et al. Hydrocortisone infusión for severe community-acquired pneumonia. A preliminary randomized study. Am J Respir Crit Care Med 2005, 171:242-248.
29. Nie W., Zhang Y., Cheng J., Xiu Q. Costicosteroids in the treatment of community-acquired pneumonia in adults: a meta-analysis. PLoS One 2012, 7:e49726.
30. Remmelts H.H., Meijvis S.C., Heijligenberg R., et al. Biomarkers define the clinical response to dexamethasone in community-acquired pneumonia. J Infect 2012, 65:25-31.
31. Gabastou J.M., Agudelo C.I., Brandileone M.C., Castañeda E., de Lemos A.P., di Fabio J.L. Grupo de Laboratorio de SIREVA II. Rev Panam Salud Publica 2008, 24:1-15.
32. Brueggemann A.B., Spratt B.G. Geographic distribution and clonal diversity of Streptococcus pneumoniae serotype 1 isolates. J Clin Microbiol 2003, 41:4966-4970.
33. Chacon-Cruz E., Velasco-Mendez Y., Navarro-Alvarez S., Rivas-Landeros R.M., Volker M.L., Lopez-Espinoza G. Pneumococcal disease: emergence of serotypes 19A and 7F following conjugate pneumococcal vaccination in a Mexican hospital. J Infect Dev Ctries 2012, 6:516-520.
34. Moberley S.A., Holden J., Tatham D.P., Andrews R.M. Vaccines for preventing pneumococcal infection in adults. Cochrane Database Syst Rev 2008, 1:CD000422.
35. Huss A., Scott P., Stuck A.E., Trotter C., Egger M. Efficacy of pneumococcal vaccination in adults: a meta-analysis. CMAJ 2009, 180:45-58.
36. Rodríguez M.A., González A.V., Gavín M.A., et al. Invasive pneumococcal disease: association between serotype, clinical presentation and lethality. Vaccine 2011, 29:5740-5746.
37. Weinberger D.M., Harboe Z.B., Sanders E.A., Ndiritu M., Klugman K.P., Rückinger S. Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis. Clin Infect Dis 2010, 51:692-699.
38. Coccia M.R., Facklam R.R., Saravolatz R.D., Manzor O. Recurrent pneumococcal bacteremia: 34 episodes in 15 patients. Clin Infect Dis 1998, 26:982-985.
39. Silva F., Cifuentes M., Pinto M.E. Results of antimicrobial susceptibility surveillance in Chile: consolidating a network. Rev Chilena Infectol 2011, 28:19-27.