Model for end-stage liver disease score versus maddrey discriminant function score in assessing short-term outcome in alcoholic hepatitis

Journal of Gastroenterology and Hepatology (Australia)

Volumn 29, Issue 3, 2014, Pages 581-588

  Kadian, Monil ^a   Kakkar, Rajesh ^a   Dhar, Minakshi ^a   Kaushik, Rajeev Mohan ^a  

^a HIMALAYAN INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Alcoholic hepatitis; India; Maddrey Differential Function; MELD score; Short term outcome

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CEPHALOSPORIN DERIVATIVE; CREATININE; FRESH FROZEN PLASMA; GLUCOSE; HEMOGLOBIN; INFUSION FLUID; LACTULOSE; PANTOPRAZOLE; PENTOXIFYLLINE; PREDNISOLONE; RIFAXIMIN; SERUM ALBUMIN; VITAMIN K GROUP;

ABDOMINAL DISTENSION; ABDOMINAL PAIN; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ALCOHOL CONSUMPTION; ALCOHOL LIVER DISEASE; ALKALINE PHOSPHATASE BLOOD LEVEL; ANOREXIA; ARTICLE; ASCITES; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; BLOOD CLOTTING DISORDER; BLOOD TRANSFUSION; BRAIN DISEASE; BRAIN HEMORRHAGE; CAUSE OF DEATH; CLINICAL ARTICLE; COMPARATIVE STUDY; CONSERVATIVE TREATMENT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIETARY INTAKE; ERYTHROCYTE COUNT; ESOPHAGUS VARICES; FEMALE; FEVER; FOLLOW UP; GASTROINTESTINAL HEMORRHAGE; GLUCOSE BLOOD LEVEL; HEMATEMESIS; HEMOGLOBIN BLOOD LEVEL; HEPATOMEGALY; HEPATORENAL SYNDROME; HOSPITAL ADMISSION; HOSPITALIZATION; HUMAN; HYPERBILIRUBINEMIA; HYPOTENSION; INDIA; INTERNATIONAL NORMALIZED RATIO; JAUNDICE; LENGTH OF STAY; LEUKOCYTE COUNT; LEUKOCYTOSIS; LIVER BIOPSY; LIVER FAILURE; LIVER HISTOLOGY; MADDREY DISCRIMINANT FUNCTION SCORE; MALE; MEAN CORPUSCULAR VOLUME; MELENA; MIDDLE AGED; MODEL FOR END STAGE LIVER DISEASE SCORE; MORTALITY; OUTCOME ASSESSMENT; OUTPATIENT DEPARTMENT; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SEPSIS; SHOCK; SHORT TERM SURVIVAL; SMOKING HABIT; SOCIAL STATUS; STATISTICS; SURVIVAL PREDICTION; SURVIVAL RATE; SURVIVOR; THROMBOCYTE COUNT; TREATMENT DURATION; VOMITING;

ALCOHOLIC HEPATITIS; INDIA; MADDREY DIFFERENTIAL FUNCTION; MELD SCORE; SHORT-TERM OUTCOME;

ADULT; CONFIDENCE INTERVALS; DISCRIMINANT ANALYSIS; END STAGE LIVER DISEASE; FEMALE; FORECASTING; HEPATITIS, ALCOHOLIC; HUMANS; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 84897600162     PISSN: 08159319     EISSN: 14401746     Source Type: Journal    
DOI: 10.1111/jgh.12400     Document Type: Article

References (36)

1. Karsan HA, Parekh S. Management of alcoholic hepatitis: current concepts. World J. Hepatol. 2012; 4: 335-341.
2. Global Status Report on Alcohol 2011. Geneva, Switzerland: World Health Organization, Department of Mental Health and Substance Abuse, 2011.
3. Potts JR, Verma S. Alcoholic hepatitis: diagnosis and management in 2012. Expert Rev. Gastroenterol. Hepatol. 2012; 6: 695-710.
4. Dunn W, Jamil LH, Brown LS etal. MELD accurately predicts mortality in patients with alcoholic hepatitis. Hepatology 2005; 41: 353-358.
5. Lucey MR, Mathurin P, Morgan TR. Alcoholic hepatitis. N. Engl. J. Med. 2009; 360: 2758-2769.
6. Imperiale TF, McCullough AJ. Do corticosteroids reduce mortality from alcoholic hepatitis? A meta-analysis of the randomized trials. Ann. Intern. Med. 1990; 113: 299-307.
7. McCullough AJ, O'Connor JF. Alcoholic liver disease: proposed recommendations for the American College of Gastroenterology. Am. J. Gastroenterol. 1998; 93: 2022-2036.
8. Rambaldi A, Saconato HH, Christensen E, Thorlund K, Wetterslev J, Gluud C. Systematic review: glucocorticosteroids for alcoholic hepatitis-a Cochrane Hepato-Biliary Group systematic review with meta-analyses and trial sequential analyses of randomized clinical trials. Aliment. Pharmacol. Ther. 2008; 27: 1167-1178.
9. Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology 2000; 119: 1637-1648.
10. Morgan TR, McClain CJ. Pentoxifylline and alcoholic hepatitis. Gastroenterology 2000; 119: 1787-1791.
11. Nguyen-Khac E, Thevenot T, Piquet MA etal. Glucocorticoids plus N-acetylcysteine in severe alcoholic hepatitis. N. Engl. J. Med. 2011; 365: 1781-1789.
12. Maddrey WC, Boitnott JK, Bedine MS, Weber FL Jr, Mezey E, White RI Jr. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology 1978; 75: 193-199.
13. Mathurin P, Duchatelle V, Ramond MJ etal. Survival and prognostic factors in patients with severe alcoholic hepatitis treated with prednisolone. Gastroenterology 1996; 110: 1847-1853.
14. Sheth M, Riggs M, Patel T. Utility of the Mayo End-Stage Liver Disease (MELD) score in assessing prognosis of patients with alcoholic hepatitis. BMC Gastroenterol. 2002; 2: 2.
15. Malinchoc M, Kamath PS, Gordon FD, Peine CJ, Rank J, ter Borg PC. A model to predict poor survival in patients undergoing transjugular intrahepatic portosystemic shunts. Hepatology 2000; 31: 864-871.
16. Kamath PS, Wiesner RH, Malinchoc M etal. A model to predict survival in patients with end-stage liver disease. Hepatology 2001; 33: 464-470.
17. Wiesner RH, McDiarmid SV, Kamath PS etal. MELD and PELD: application of survival models to liver allocation. Liver Transpl. 2001; 7: 567-580.
18. Wiesner R, Edwards E, Freeman R etal. Model for end-stage liver disease (MELD) and allocation of donor livers. Gastroenterology 2003; 124: 91-96.
19. Mailliard ME, Sorrell MF. Alcoholic liver disease. In: Fauci AS, Braunwald E, Kasper DL etal., eds. Harrison's Principles of Internal Medicine, 17th edn. New York: McGraw-Hill, 2008; 1969-1971.
20. DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988; 44: 837-845.
21. Srikureja W, Kyulo NL, Runyon BA, Hu KQ. MELD score is a better prognostic model than Child-Turcotte-Pugh score or discriminant function score in patients with alcoholic hepatitis. J. Hepatol. 2005; 42: 700-706.
22. Said A, Williams J, Holden J etal. Model for end stage liver disease score predicts mortality across a broad spectrum of liver disease. J. Hepatol. 2004; 40: 897-903.
23. Soultati AS, Dourakis SP, Alexopoulou A, Deutsch M, Vasilieva L, Archimandritis AJ. Predicting utility of a model for end stage liver disease in alcoholic liver disease. World J. Gastroenterol. 2006; 12: 4020-4025.
24. Palaniyappan N, Subramanian V, Ramappa V, Ryder SD, Kaye P, Aithal GP. The utility of scoring systems in predicting early and late mortality in alcoholic hepatitis: whose score is it anyway? Int. J. Hepatol. 2012; 2012: 624675.
25. Forrest EH, Evans CDJ, Stewart S etal. Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score. Gut 2005; 54: 1174-1179.
26. Louvet A, Naveau S, Abdelnour M etal. The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids. Hepatology 2007; 45: 1348-1354.
27. Bosch J, Garcia-Pagan JC. Complications of cirrhosis. I. Portal hypertension. J. Hepatol. 2000; 32 (Suppl. 1): 141-156.
28. Ripoll C, Banares R, Rincon D etal. Influence of hepatic venous pressure gradient on the prediction of survival of patients with cirrhosis in the MELD era. Hepatology 2005; 42: 793-801.
29. Sandahl TD, Jepsen P, Ott P, Vilstrup H. Validation of prognostic scores for clinical use in patients with alcoholic hepatitis. Scand. J. Gastroenterol. 2011; 46: 1127-1132.
30. O'Shea RS, Dasarathy S, McCullough AJ. Alcoholic liver disease. Hepatology 2010; 51: 307-328.
31. Orrego H, Israel Y, Blake JE, Medline A. Assessment of prognostic factors in alcoholic liver disease: toward a global quantitative expression of severity. Hepatology 1983; 3: 896-905.
32. Hosmer DW, Lemeshow S. Applied Logistic Regression, 2nd edn. New York: John Wiley & Sons, 2000.
33. Kulkarni K, Tran T, Medrano M, Yoffe B, Goodgame R. The role of the discriminant factor in the assessment and treatment of alcoholic hepatitis. J. Clin. Gastroenterol. 2004; 38: 453-459.
34. Mathurin P, Mendenhall CL, Carithers RL Jr etal. Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo controlled double blind trials of corticosteroids in severe AH. J. Hepatol. 2002; 36: 480-487.
35. Mendenhall CL, Anderson S, Garcia-Pont P etal. Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone. N. Engl. J. Med. 1984; 311: 1464-1470.
36. Carithers RL Jr, Herlong HF, Diehl AM etal. Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial. Ann. Intern. Med. 1989; 110: 685-690.