-
1
-
-
48449101416
-
The role of vascular endothelial growth factor and other endogenous interplayers in agerelated macular degeneration
-
Grisanti S, Tatar O (2008) The role of vascular endothelial growth factor and other endogenous interplayers in agerelated macular degeneration. Prog Retin Eye Res 27: 372–390
-
(2008)
Prog Retin Eye Res
, vol.27
, pp. 372-390
-
-
Grisanti, S.1
Tatar, O.2
-
2
-
-
25144511910
-
The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions
-
Takahashi H, Shibuya M (2005) The vascular endothelial growth factor (VEGF)/VEGF receptor system and its role under physiological and pathological conditions. Clin Sci 109:227–241
-
(2005)
Clin Sci
, vol.109
, pp. 227-241
-
-
Takahashi, H.1
Shibuya, M.2
-
3
-
-
0032493654
-
2 ¢ -Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF 165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain
-
Ruckman J, Green LS, Beeson J, Waugh S, Gillette WL, Henninger DD, Claesson-Welsh L, Janjić N (1998) 2 ¢ -Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF 165). Inhibition of receptor binding and VEGF-induced vascular permeability through interactions requiring the exon 7-encoded domain. J Biol Chem 273:20556–20567
-
(1998)
J Biol Chem
, vol.273
, pp. 20556-20567
-
-
Ruckman, J.1
Green, L.S.2
Beeson, J.3
Waugh, S.4
Gillette, W.L.5
Henninger, D.D.6
Claesson-Welsh, L.7
Janjić, N.8
-
4
-
-
0032707345
-
Oligonucleotide NX1838 inhibits VEGF165-mediated cellular responses in vitro
-
Bell C, Lynam E, Landfair DJ, Janjic N, Wiles ME (1999) Oligonucleotide NX1838 inhibits VEGF165-mediated cellular responses in vitro. In Vitro Cell Dev Biol Anim 35:533–542
-
(1999)
Vitro Cell Dev Biol Anim
, vol.35
, pp. 533-542
-
-
Bell, C.1
Lynam, E.2
Landfair, D.J.3
Janjic, N.4
Wiles, M.E.5
-
5
-
-
0032876515
-
Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide- aptamer (NX1838) in rhesus monkeys
-
Tucker CE, Chen LS, Judkins MB, Farmer JA, Gill SC, Drolet DW (1999) Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide- aptamer (NX1838) in rhesus monkeys. J Chromatogr B Biomed Sci Appl 732:203–212
-
(1999)
J Chromatogr B Biomed Sci Appl
, vol.732
, pp. 203-212
-
-
Tucker, C.E.1
Chen, L.S.2
Judkins, M.B.3
Farmer, J.A.4
Gill, S.C.5
Drolet, D.W.6
-
6
-
-
0034466813
-
Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys
-
Drolet DW, Nelson J, Tucker CE, Zack PM, Nixon K, Bolin R, Judkins MB, Farmer JA, Wolf JL, Gill SC, Bendele RA (2000) Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer (NX1838) following injection into the vitreous humor of rhesus monkeys. Pharm Res 17:1503–1510
-
(2000)
Pharm Res
, vol.17
, pp. 1503-1510
-
-
Drolet, D.W.1
Nelson, J.2
Tucker, C.E.3
Zack, P.M.4
Nixon, K.5
Bolin, R.6
Judkins, M.B.7
Farmer, J.A.8
Wolf, J.L.9
Gill, S.C.10
Bendele, R.A.11
-
7
-
-
0037407757
-
VEGF164 is proinflammatory in the diabetic retina
-
Ishida S, Usui T, Yamashiro K, Ahmed E, Carrasquillo KG, Amano S, Hida T, Oguchi Y, Adamis AP (2003) VEGF164 is proinflammatory in the diabetic retina. Invest Ophthalmol Vis Sci 44:2155–2162
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 2155-2162
-
-
Ishida, S.1
Usui, T.2
Yamashiro, K.3
Ahmed, E.4
Carrasquillo, K.G.5
Amano, S.6
Hida, T.7
Oguchi, Y.8
Adamis, A.P.9
-
8
-
-
0942287258
-
VEGF 164(165) as the pathological isoform: Differential leukocyte and endothelial responses through VEGFR1 and VEGFR2
-
Usui T, Ishida S, Yamashiro K, Kaji Y, Poulaki V, Moore J, Moore T, Amano S, Horikawa Y, Dartt D, Golding M, Shima DT, Adamis AP (2004) VEGF 164(165) as the pathological isoform: differential leukocyte and endothelial responses through VEGFR1 and VEGFR2. Invest Ophthalmol Vis Sci 45:368–374
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 368-374
-
-
Usui, T.1
Ishida, S.2
Yamashiro, K.3
Kaji, Y.4
Poulaki, V.5
Moore, J.6
Moore, T.7
Amano, S.8
Horikawa, Y.9
Dartt, D.10
Golding, M.11
Shima, D.T.12
Adamis, A.P.13
-
9
-
-
33749632278
-
Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration
-
Ferrara N, D’Amico L, Shams N, Lowman H, Kim R (2006) Development of ranibizumab, an anti-vascular endothelial growth factor antigen binding fragment, as therapy for neovascular age-related macular degeneration. Retina 26: 850–870
-
(2006)
Retina
, vol.26
, pp. 850-870
-
-
Ferrara, N.1
D’Amico, L.2
Shams, N.3
Lowman, H.4
Kim, R.5
-
11
-
-
33747874091
-
A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration
-
Nguyen QD, Shah SM, Hafiz G, Quinlan E, Sung J, Chu K, Cedarbaum JM, Campochiaro PA, CLEAR-AMD 1 Study Group (2006) A phase I trial of an IV-administered vascular endothelial growth factor trap for treatment in patients with choroidal neovascularization due to age-related macular degeneration. Ophthalmology 113:1522.e1–1522.e14
-
(2006)
Ophthalmology 113
, pp. 1522.e1-1522.e14
-
-
Nguyen, Q.D.1
Shah, S.M.2
Hafiz, G.3
Quinlan, E.4
Sung, J.5
Chu, K.6
Cedarbaum, J.M.7
Campochiaro, P.A.8
-
12
-
-
0037231664
-
Cytokine traps: Multi-component, highaf finity blockers of cytokine action
-
Economides AN, Carpenter LR, Rudge JS, Wong V, Koehler- Stec EM, Hartnett C, Pyles EA, Xu X, Daly TJ, Young MR, Fandl JP, Lee F, Carver S, McNay J, Bailey K, Ramakanth S, Hutabarat R, Huang TT, Radziejewski C, Yancopoulos GD, Stahl N (2003) Cytokine traps: multi-component, highaf finity blockers of cytokine action. Nat Med 9:47–52
-
(2003)
Nat Med
, vol.9
, pp. 47-52
-
-
Economides, A.N.1
Carpenter, L.R.2
Rudge, J.S.3
Wong, V.4
Koehler- Stec, E.M.5
Hartnett, C.6
Pyles, E.A.7
Xu, X.8
Daly, T.J.9
Young, M.R.10
Fandl, J.P.11
Lee, F.12
Carver, S.13
McNay, J.14
Bailey, K.15
Ramakanth, S.16
Hutabarat, R.17
Huang, T.T.18
Radziejewski, C.19
Yancopoulos, G.D.20
Stahl, N.21
more..
-
13
-
-
67649872364
-
Engineered protein scaffolds as next-generation antibody therapeutics
-
Gebauer M, Skerra A (2009) Engineered protein scaffolds as next-generation antibody therapeutics. Curr Opin Chem Biol 3:245–255
-
(2009)
Curr Opin Chem Biol
, vol.3
, pp. 245-255
-
-
Gebauer, M.1
Skerra, A.2
-
14
-
-
58149478117
-
Novel anti- VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization
-
Pechan P, Rubin H, Lukason M, Ardinger J, DuFresne E, Hauswirth WW, Wadsworth SC, Scaria A (2009) Novel anti- VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization. Gene Ther 16:10–16
-
(2009)
Gene Ther
, vol.16
, pp. 10-16
-
-
Pechan, P.1
Rubin, H.2
Lukason, M.3
Ardinger, J.4
Dufresne, E.5
Hauswirth, W.W.6
Wadsworth, S.C.7
Scaria, A.8
-
17
-
-
32944481724
-
Adenoviral vector-delivered pigment epithelium-derived factor for neovascular agerelated macular degeneration: Results of a phase I clinical trial
-
Campochiaro PA, Nguyen QD, Shah SM, Klein ML, Holz E, Frank RN, Saperstein DA, Gupta A, Stout JT, Macko J, DiBartolomeo R, Wei LL (2006) Adenoviral vector-delivered pigment epithelium-derived factor for neovascular agerelated macular degeneration: results of a phase I clinical trial. Hum Gene Ther 17:167–176
-
(2006)
Hum Gene Ther
, vol.17
, pp. 167-176
-
-
Campochiaro, P.A.1
Nguyen, Q.D.2
Shah, S.M.3
Klein, M.L.4
Holz, E.5
Frank, R.N.6
Saperstein, D.A.7
Gupta, A.8
Stout, J.T.9
Macko, J.10
Dibartolomeo, R.11
Wei, L.L.12
-
18
-
-
0035404544
-
Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin
-
Mori K, Ando A, Gehlbach P, Nesbitt D, Takahashi K, Goldsteen D, Penn M, Chen CT, Mori K, Melia M, Phipps S, Moffat D, Brazzell K, Liau G, Dixon KH, Campochiaro PA (2001) Inhibition of choroidal neovascularization by intravenous injection of adenoviral vectors expressing secretable endostatin. Am J Pathol 159:313–3201
-
(2001)
Am J Pathol
, vol.159
, pp. 313-3201
-
-
Mori, K.1
Ando, A.2
Gehlbach, P.3
Nesbitt, D.4
Takahashi, K.5
Goldsteen, D.6
Penn, M.7
Chen, C.T.8
Mori, K.9
Melia, M.10
Phipps, S.11
Moffat, D.12
Brazzell, K.13
Liau, G.14
Dixon, K.H.15
Campochiaro, P.A.16
-
19
-
-
36849081545
-
Tumor-selective vessel occlusions by platelets after vascular targeting chemotherapy using paclitaxel encapsulated in cationic liposomes
-
Strieth S, Nussbaum CF, Eichhorn ME, Fuhrmann M, Teifel M, Michaelis U, Berghaus A, Dellian M (2008) Tumor-selective vessel occlusions by platelets after vascular targeting chemotherapy using paclitaxel encapsulated in cationic liposomes. Int J Cancer 122:452–460
-
(2008)
Int J Cancer
, vol.122
, pp. 452-460
-
-
Strieth, S.1
Nussbaum, C.F.2
Eichhorn, M.E.3
Fuhrmann, M.4
Teifel, M.5
Michaelis, U.6
Berghaus, A.7
Dellian, M.8
-
20
-
-
0042767766
-
Intravitreous anti-raf-1 kinase antisense oligonucleotide as an angioinhibitory agent in porcine preretinal neovascularization
-
Danis R, Criswell M, Orge F, Wancewicz E, Stecker K, Henry S, Monia BD (2003) Intravitreous anti-raf-1 kinase antisense oligonucleotide as an angioinhibitory agent in porcine preretinal neovascularization. Curr Eye Res 26:45–54
-
(2003)
Curr Eye Res
, vol.26
, pp. 45-54
-
-
Danis, R.1
Criswell, M.2
Orge, F.3
Wancewicz, E.4
Stecker, K.5
Henry, S.6
Monia, B.D.7
-
21
-
-
0038748037
-
Small interfering RNA (SiRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model
-
Reich SJ, Fosnot J, Kuroki A, Tang W, Yang X, Maguire AM, Bennett J, Tolentino MJ (2003) Small interfering RNA (siRNA) targeting VEGF effectively inhibits ocular neovascularization in a mouse model. Mol Vis 9:210–216
-
(2003)
Mol Vis
, vol.9
, pp. 210-216
-
-
Reich, S.J.1
Fosnot, J.2
Kuroki, A.3
Tang, W.4
Yang, X.5
Maguire, A.M.6
Bennett, J.7
Tolentino, M.J.8
-
22
-
-
79956218863
-
Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration
-
The CATT Research Group, Martin DF, Maguire MG, Ying GS, Grunwald JE, Fine SL, Jaffe GJ (2011) Ranibizumab and Bevacizumab for Neovascular Age-Related Macular Degeneration. N Engl J Med 364:1897–1908
-
(2011)
N Engl J Med
, vol.364
, pp. 1897-1908
-
-
Martin, D.F.1
Maguire, M.G.2
Ying, G.S.3
Grunwald, J.E.4
Fine, S.L.5
Jaffe, G.J.6
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