Oral delivery of plant-derived HIV-1 p24 antigen in low doses shows a superior priming effect in mice compared to high doses

Vaccine

Volumn 32, Issue 20, 2014, Pages 2288-2293

  Lindh, Ingrid ^a,e   Bråve, Andreas ^b   Hallengärd, David ^c   Hadad, Ronza ^a   Kalbina, Irina ^a   Strid, Åke ^a   Andersson, Sören ^a,d  

^a ÖREBRO UNIVERSITY   (Sweden)

^b Swedish Institute of Disease Control (SMI)   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Arabidopsis thaliana; Carrot; Edible vaccine; HIV 1 p24; Oral immunization; Transgenic plants

Indexed keywords

ANTIGEN P24; HUMAN IMMUNODEFICIENCY VIRUS 1 P24 ANTIGEN; HUMAN IMMUNODEFICIENCY VIRUS ANTIGEN; IMMUNOGLOBULIN G ANTIBODY; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARABIDOPSIS THALIANA; ARTICLE; CARROT; CONTROLLED STUDY; DOSE RESPONSE; DRUG DELIVERY SYSTEM; DRUG DOSE COMPARISON; DRUG MEGADOSE; FEMALE; HEPATITIS B; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMORAL IMMUNITY; IMMUNIZATION; IMMUNOGENICITY; INTESTINE LYMPHATIC TISSUE; LOW DRUG DOSE; LYMPHOCYTE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC PLANT;

ARABIDOPSIS THALIANA; CARROT; EDIBLE VACCINE; HIV-1 P24; ORAL IMMUNIZATION; TRANSGENIC PLANTS;

ADMINISTRATION, ORAL; AIDS VACCINES; ANIMALS; ARABIDOPSIS; DAUCUS CAROTA; DOSE-RESPONSE RELATIONSHIP, IMMUNOLOGIC; FEMALE; HIV ANTIBODIES; HIV CORE PROTEIN P24; IMMUNITY, HUMORAL; IMMUNIZATION, SECONDARY; IMMUNOGLOBULIN G; MALE; MICE; MICE, INBRED BALB C; MICE, TRANSGENIC; PLANTS, GENETICALLY MODIFIED;

EID: 84897502968     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2014.02.073     Document Type: Article

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