Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma

BMC Cancer

Volumn 14, Issue 1, 2014, Pages

  Ma, Ji ^a,b   Guo, Yan ^a   Chen, Suning ^a   Zhong, Cuiping ^b   Xue, Yan ^a   Zhang, Yuan ^a   Lai, Xiaofeng ^a   Wei, Yifang ^a   Yu, Shentong ^a   Zhang, Jian ^a   Liu, Wenchao ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b LANZHOU GENERAL HOSPITAL   (China)

Author keywords

Breast cancer; Estrogen receptor; Metformin; Tamoxifen

Indexed keywords

DNA; ESTROGEN RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MAMMALIAN TARGET OF RAPAMYCIN; METFORMIN; PROTEIN BAX; PROTEIN BCL 2; S6 KINASE; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CANCER INHIBITION; CELL PROLIFERATION; CELL SURVIVAL; COLONY FORMATION; CONTROLLED STUDY; DNA REPLICATION; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; HUMAN; HUMAN CELL; IN VIVO STUDY; MONOTHERAPY; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL PROLIFERATION; FEMALE; HUMANS; MAMMARY NEOPLASMS, EXPERIMENTAL; MCF-7 CELLS; METFORMIN; MICE; MICE, NUDE; RECEPTORS, ESTROGEN; SIGNAL TRANSDUCTION; TAMOXIFEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84897494829     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/1471-2407-14-172     Document Type: Article

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