Prognostic significance of being overweight and obese at diagnosis in children with acute lymphoblastic leukemia

Journal of Pediatric Hematology/Oncology

Volumn 36, Issue 3, 2014, Pages 234-236

  Aldhafiri, Fahad K ^a   McColl, John H ^b   Reilly, John J ^c  

^a QUEEN MOTHER S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF STRATHCLYDE   (United Kingdom)

Author keywords

Acute lymphoblastic leukemia; BMI; obesity; overweight

Indexed keywords

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; AGE DISTRIBUTION; ARTICLE; BODY MASS; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; HIGH RISK POPULATION; HUMAN; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; OBESITY; PRIORITY JOURNAL; PROGNOSIS; RECURRENCE RISK; SECONDARY ANALYSIS; SEX DIFFERENCE; UNITED KINGDOM;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; MALE; NEOPLASM RECURRENCE, LOCAL; OBESITY; OVERWEIGHT; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROGNOSIS; RISK FACTORS;

EID: 84897492159     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0000000000000056     Document Type: Article

References (21)

1. Institute of Medicine Report. The role of obesity in cancer survival and recurrence. Available at: Http://www.iom.edu Reports/2012/The-Role-of-Obesity- in-Cancer-Survival-and-Recur rence.aspx. Accessed May 25, 2012
2. Jeha S, Pui CH. Risk adapted treatment of pediatric ALL. Hematol Oncol Clin North Am. 2009;23:973-990
3. Butturini AM, Dorey FJ, Lange BJ, et al. Obesity and outcome in pediatric ALL. J Clin Oncol. 2007;25:2063-2069
4. Gelelete CB, Pereira SH, Azevedo AMB, et al. Overweight as a prognostic factor in children with ALL. Obesity. 2011;19: 1908-1911
5. Hijya N, Panetta JC, Zhou Y, et al. BMI does not influence pharmacokinetics or outcome of treatment in children with ALL. Blood. 2006;108:3997-4002
6. Baillargeon J, Langevin AM, Lewis M, et al. Obesity and survival in a cohort of predominantly Hispanic children with ALL. J Pediatr Hematol Oncol. 2006;28:575-578
7. Reilly JJ. Tackling the obesity epidemic: New approaches. Arch Dis Child. 2006;91:724-726
8. Reilly JJ. Obesity During and After Treatment for Childhood Cancer. In: Endocrinopathy After Childhood Cancer Treatment. Basel: WHB Wallace & CJH Kelnar, Karger; 2009:40-58
9. Weir J, Reilly JJ, McColl JH. No evidence of an effect of nutritional status on clinical outcome in childhood ALL. J Pediatr Hematol Oncol. 1998;20:534-538
10. Cole TJ, Bellizzi MC, Flegal KM, et al. Establishing a standard definition for child overweight and obesity worldwide: International survey. Br Med J. 2000;320:1240-1243
11. Cole TJ, Flegal KM, Nicholls D, et al. Body mass index cutoffs to define thinness in children and adolescents: International survey. Br Med J. 2007;335:194-197
12. Lange BJ, Gerbing RB, Feusner J, et al. Mortality in overweight and underweight children with AML. JAMA. 2005;293:203-211
13. Zuccaro P, Guandalini S, Pacifici R, et al. Fat body mass and pharmacokinetics of oral 6-MP in children with ALL. Ther Drug Monit. 1991;13:37-41
14. Reilly JJ, Kelnar CJ, Alexander DW, et al. Health consequences of obesity: Systematic review. Arch Dis Child. 2003;88:748-752
15. Reilly JJ, Kelly J. Long-term impact of childhood obesity on adult morbidity and premature mortality: Systematic review. Int J Obes. 2011;35:891-898
16. Ethier MC, Alexander S, Abla O, et al. Association between obesity at diagnosis and weight change during induction and survival in pediatric acute lymphoblastic leukaemia. Leuk Lymphoma. 2012;53:1677-1681
17. Castillo JJ, Reagan JL, Ingham RR, et al. Obesity but not overweight increases the incidence and mortality of leukaemia in adults: Meta-analysis of prospective cohort studies. Leuk Res. 2012;36:868-875
18. Lightfoot TJ, Johnston WT, Simpson J, et al. Survival from childhood ALL: The impact of social inequality in the UK. Eur J Cancer. 2012;48:263-269
19. Reilly JJ, Kelly J, Wilson D. Accuracy of simple clinical and epidemiological definitions of childhood obesity. Obes Rev. 2010;11:645-655
20. Warner J, Cowan F, Dunstan F, et al. The validity of BMI for the assessment of adiposity in children with disease states. Ann Hum Biol. 1997;24:209-215
21. Aldhafiri F, Al-Nasser A, Al-Sugair A, et al. Obesity and metabolic syndrome in adolescent survivors of standard risk ALL in Saudi Arabia. Pediatr Blood Cancer. 2012;59:133-137