Generation of site-appropriate tissue by a living cellular sheet in the treatment of mucogingival defects

Journal of Periodontology

Volumn 85, Issue 4, 2014, Pages

  Scheyer, E Todd ^a   Nevins, Marc L ^b   Neiva, Rodrigo ^c   Cochran, David L ^d   Giannobile, William V ^e   Woo, Sook Bin ^f   King, William N ^g   Spitznagel Jr , John K ^h   Bates, Damien ⁱ   McGuire, Michael K ^a  

^a Private Practice ^*  (United States)

^b Private Practice   (United States)

^c UNIVERSITY OF FLORIDA COLLEGE OF DENTISTRY   (United States)

^d UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^e Michigan Center for Oral Health Research   (United States)

^f Pathology Services Inc Cambridge   (United States)

^g Western Statistical Consulting   (United States)

^h Organogenesis   (United States)

ⁱ ALLERGAN INC   (United States)

Author keywords

Gingival recession; Periodontics; Regenerative medicine; Tissue engineering

Indexed keywords

COLLAGEN; KERATIN;

ALLOGRAFT; ANIMAL; AUTOGRAFT; BIOPSY; BOVINAE; CICATRIX; COLOR; COMPARATIVE STUDY; CONTROLLED STUDY; DENTAL PROCEDURE; EPITHELIUM CELL; FIBROBLAST; FOLLOW UP; GINGIVA; GINGIVAL DISEASES; HUMAN; KELOID; KERATINOCYTE; MOUTH MUCOSA; PATHOLOGY; PHOTOGRAPHY; PROCEDURES; RANDOMIZED CONTROLLED TRIAL; TISSUE ENGINEERING; TISSUE SCAFFOLD; TRANSPLANTATION; TREATMENT OUTCOME;

ALLOGRAFTS; ANIMALS; AUTOGRAFTS; BIOPSY; CATTLE; CICATRIX; COLLAGEN; COLOR; EPITHELIAL CELLS; ESTHETICS, DENTAL; FIBROBLASTS; FOLLOW-UP STUDIES; GINGIVA; GINGIVAL DISEASES; HUMANS; KELOID; KERATINOCYTES; KERATINS; MOUTH MUCOSA; PHOTOGRAPHY; TISSUE ENGINEERING; TISSUE SCAFFOLDS; TREATMENT OUTCOME;

EID: 84897453293     PISSN: 00223492     EISSN: None     Source Type: Journal    
DOI: 10.1902/jop.2013.130348     Document Type: Article

References (21)

1. Harris RJ. Clinical evaluation of 3 techniques to augment keratinized tissue without root coverage. J Periodontol 2001;72:932-938.
2. McGuire MK, Scheyer ET, Nunn ME, Lavin PT. A pilot study to evaluate a tissue-engineered bilayered cell therapy as an alternative to tissue from the palate. J Periodontol 2008;79:1847-1856.
3. Karring T, Ostergaard E, Löe H. Conservation of tissue specificity after heterotopic transplantation of gingiva and alveolar mucosa. J Periodontal Res 1971;6:282-293.
4. Karring T, Lang NP, Löe H. The role of gingival connective tissue in determining epithelial differentiation. J Periodontal Res 1975;10:1-11.
5. Wei PC, Laurell L, Lingen MW, Geivelis M. Acellular dermal matrix allografts to achieve increased attached gingiva. Part 2. A histological comparative study. J Periodontol 2002;73:257-265.
6. Cooke JW, Sarment DP, Whitesman LA, et al. Effect of rhPDGF-BB delivery on mediators of periodontal wound repair. Tissue Eng 2006;12:1441-1450.
7. Giannobile WV, Somerman MJ. Growth and amelogenin-like factors in periodontal wound healing. A systematic review. Ann Periodontol 2003;8:193-204.
8. Veves A, Falanga V, Armstrong DG, Sabolinski ML; Apligraf Diabetic Foot Ulcer Study. Graftskin, a human skin equivalent, is effective in the management of noninfected neuropathic diabetic foot ulcers: A prospective randomized multicenter clinical trial. Diabetes Care 2001;24:290-295.
9. Muhart M, McFalls S, Kirsner RS, et al. Behavior of tissue-engineered skin: A comparison of a living skin equivalent, autograft, and occlusive dressing in human donor sites. Arch Dermatol 1999;135:913-918.
10. Waymack P, Duff RG, Sabolinski M; The Apligraf Burn Study Group. The effect of a tissue engineered bilayered living skin analog, over meshed splitthickness autografts on the healing of excised burn wounds. Burns 2000;26:609-619.
11. Falanga V, Margolis D, Alvarez O, et al; Human Skin Equivalent Investigators Group. Rapid healing of venous ulcers and lack of clinical rejection with an allogeneic cultured human skin equivalent. Arch Dermatol 1998;134:293-300.
12. McGuire MK, Scheyer ET, Nevins ML, et al. Living cellular construct for increasing the width of keratinized gingiva: Results from a randomized, withinpatient, controlled trial. J Periodontol 2011;82:1414-1423.
13. Brem H, Young J, Tomic-Canic M, Isaacs C, Ehrlich HP. Clinical efficacy and mechanism of bilayered living human skin equivalent (HSE) in treatment of diabetic foot ulcers. Surg Technol Int 2003;11:23-31.
14. Griffiths M, Ojeh N, Livingstone R, Price R, Navsaria H. Survival of Apligraf in acute human wounds. Tissue Eng 2004;10:1180-1195.
15. Morelli T, Neiva R, Nevins ML, et al. Angiogenic biomarkers and healing of living cellular constructs. J Dent Res 2011;90:456-462.
16. Nevins ML. Tissue-engineered bilayered cell therapy for the treatment of oral mucosal defects: A case series. Int J Periodontics Restorative Dent 2010;30:31-39.
17. Ferguson MW, O'Kane S. Scar-free healing: From embryonic mechanisms to adult therapeutic intervention. Philos Trans R Soc Lond B Biol Sci 2004; 359:839-850.
18. Cairo F, Rotundo R, Miller PD, Pini Prato GP. Root coverage esthetic score: A system to evaluate the esthetic outcome of the treatment of gingival recession through evaluation of clinical cases. J Periodontol 2009;80:705-710.
19. Hsia HC, Schwarzbauer JE. Meet the tenascins: Multifunctional and mysterious. J Biol Chem 2005; 280:26641-26644.
20. Wong JW, Gallant-Behm C, Wiebe C, et al. Wound healing in oral mucosa results in reduced scar formation as compared with skin: Evidence from the red Duroc pig model and humans. Wound Repair Regen 2009;17:717-729.
21. Wei PC, Laurell L, Geivelis M, Lingen MW, Maddalozzo D. Acellular dermal matrix allografts to achieve increased attached gingiva. Part 1. A clinical study. J Periodontol 2000;71:1297-1305.