CHIP-MYTH: A novel interactive proteomics method for the assessment of agonist-dependent interactions of the human β2-adrenergic receptor

Biochemical and Biophysical Research Communications

Volumn 445, Issue 4, 2014, Pages 746-756

  Kittanakom, Saranya ^a   Barrios Rodiles, Miriam ^b   Petschnigg, Julia ^a   Arnoldo, Anthony ^a   Wong, Victoria ^a   Kotlyar, Max ^c   Heisler, Lawrence E ^a   Jurisica, Igor ^a,c,d   Wrana, Jeffrey L ^b   Nislow, Corey ^e   Stagljar, Igor ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

drug dependent protein interactions; G protein coupled receptors; high throughput screening; LUMIER assay; membrane two hybrid assay; protein protein interactions

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; MEMBRANE PROTEIN; SALMETEROL;

ANALYTIC METHOD; ARTICLE; CONTROLLED STUDY; DISSOCIATION; DNA MICROARRAY; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LUMINESCENCE BASED MAMMALIAN INTERACTOME ASSAY; MAMMAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEOMICS; QUANTITATIVE ANALYSIS; RECEPTOR UPREGULATION; SCREENING; SIGNAL TRANSDUCTION; TECHNOLOGY; TWO HYBRID SYSTEM;

MAMMALIA;

DRUG-DEPENDENT PROTEIN INTERACTIONS; G-PROTEIN COUPLED RECEPTORS; HIGH-THROUGHPUT SCREENING; LUMIER ASSAY; MEMBRANE TWO-HYBRID ASSAY; PROTEIN-PROTEIN INTERACTIONS;

ADRENERGIC BETA-2 RECEPTOR AGONISTS; ALBUTEROL; ANIMALS; HEK293 CELLS; HUMANS; MODELS, MOLECULAR; PROTEIN INTERACTION MAPPING; PROTEIN INTERACTION MAPS; PROTEOMICS; RECEPTORS, ADRENERGIC, BETA-2; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION; TWO-HYBRID SYSTEM TECHNIQUES; UBIQUITIN;

EID: 84897449272     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.02.033     Document Type: Article

References (31)

1. M.C. Lagerstrom, and H.B. Schioth Structural diversity of G protein-coupled receptors and significance for drug discovery Nat. Rev. Drug. Discov. 7 2008 339 357
2. R. Lappano, and M. Maggiolini G protein-coupled receptors: novel targets for drug discovery in cancer Nat. Rev. Drug. Discov. 10 2011 47 60
3. J.P. Overington, B. Al-Lazikani, and A.L. Hopkins How many drug targets are there? Nat. Rev. Drug. Discov. 5 2006 993 996
4. N. Johnsson, and A. Varshavsky Split ubiquitin as a sensor of protein interactions in vivo Proc. Natl. Acad. Sci. USA 91 1994 10340 10344
5. I. Stagljar, C. Korostensky, N. Johnsson, and S. te Heesen A genetic system based on split-ubiquitin for the analysis of interactions between membrane proteins in vivo Proc. Natl. Acad. Sci. USA 95 1998 5187 5192
6. J. Snider, S. Kittanakom, D. Damjanovic, J. Curak, V. Wong, and I. Stagljar Detecting interactions with membrane proteins using a membrane two-hybrid assay in yeast Nat. Protoc. 5 2010 1281 1293
7. Y.L. Deribe, P. Wild, A. Chandrashaker, J. Curak, M.H. Schmidt, Y. Kalaidzidis, N. Milutinovic, I. Kratchmarova, L. Buerkle, M.J. Fetchko, P. Schmidt, S. Kittanakom, K.R. Brown, I. Jurisica, B. Blagoev, M. Zerial, I. Stagljar, and I. Dikic Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6 Sci. Signal. 2 2009 ra84
8. J. Jin, S. Kittanakom, V. Wong, B.A. Reyes, E.J. Van Bockstaele, I. Stagljar, W. Berrettini, and R. Levenson Interaction of the mu-opioid receptor with GPR177 (Wntless) inhibits Wnt secretion: potential implications for opioid dependence BMC Neurosci. 11 2010 33
9. J. Snider, A. Hanif, M.E. Lee, K. Jin, A.R. Yu, C. Graham, M. Chuk, D. Damjanovic, M. Wierzbicka, P. Tang, D. Balderes, V. Wong, M. Jessulat, K.D. Darowski, B.J. San Luis, I. Shevelev, S.L. Sturley, C. Boone, J.F. Greenblatt, Z. Zhang, C.M. Paumi, M. Babu, H.O. Park, S. Michaelis, and I. Stagljar Mapping the functional yeast ABC transporter interactome Nat. Chem. Biol. 9 2013 565 572
10. C.M. Paumi, J. Menendez, A. Arnoldo, K. Engels, K.R. Iyer, S. Thaminy, O. Georgiev, Y. Barral, S. Michaelis, and I. Stagljar Mapping protein-protein interactions for the yeast ABC transporter Ycf1p by integrated split-ubiquitin membrane yeast two-hybrid analysis Mol. Cell 26 2007 15 25
11. M. Tanowitz, and M. von Zastrow Identification of protein interactions by yeast two-hybrid screening and coimmunoprecipitation Methods Mol. Biol. 259 2004 353 369
12. F. Ciruela Fluorescence-based methods in the study of protein-protein interactions in living cells Curr. Opin. Biotechnol. 19 2008 338 343
13. F. Ciruela, J.P. Vilardaga, and V. Fernandez-Duenas Lighting up multiprotein complexes: lessons from GPCR oligomerization Trends Biotechnol. 28 2010 407 415
14. L. Prezeau, M.L. Rives, L. Comps-Agrar, D. Maurel, J. Kniazeff, and J.P. Pin Functional crosstalk between GPCRs: with or without oligomerization Curr. Opin. Pharmacol. 10 2010 6 13
15. K. Iyer, L. Burkle, D. Auerbach, S. Thaminy, M. Dinkel, K. Engels, and I. Stagljar Utilizing the split-ubiquitin membrane yeast two-hybrid system to identify protein-protein interactions of integral membrane proteins Sci. STKE 2005 2005 pl3
16. S. Kittanakom, M. Chuk, V. Wong, J. Snyder, D. Edmonds, A. Lydakis, Z. Zhang, D. Auerbach, and I. Stagljar Analysis of membrane protein complexes using the split-ubiquitin membrane yeast two-hybrid (MYTH) system Methods Mol. Biol. 548 2009 247 271
17. M. Barrios-Rodiles, K.R. Brown, B. Ozdamar, R. Bose, Z. Liu, R.S. Donovan, F. Shinjo, Y. Liu, J. Dembowy, I.W. Taylor, V. Luga, N. Przulj, M. Robinson, H. Suzuki, Y. Hayashizaki, I. Jurisica, and J.L. Wrana High-throughput mapping of a dynamic signaling network in mammalian cells Science 307 2005 1621 1625
18. J.D. Ellis, M. Barrios-Rodiles, R. Colak, M. Irimia, T. Kim, J.A. Calarco, X. Wang, Q. Pan, D. O'Hanlon, P.M. Kim, J.L. Wrana, and B.J. Blencowe Tissue-specific alternative splicing remodels protein-protein interaction networks Mol. Cell 46 2012 884 892
19. M. Johnson Beta2-adrenoceptors: mechanisms of action of beta2-agonists Paediatr. Respir. Rev. 2 2001 57 62
20. M. Johnson Molecular mechanisms of beta(2)-adrenergic receptor function, response, and regulation J. Allergy Clin. Immunol. 117 2006 18 24 (quiz 25)
21. K.L. Pierce, R.T. Premont, and R.J. Lefkowitz Seven-transmembrane receptors Nat. Rev. Mol. Cell Biol. 3 2002 639 650
22. S.C. Prinster, C. Hague, and R.A. Hall Heterodimerization of g protein-coupled receptors: specificity and functional significance Pharmacol. Rev. 57 2005 289 298
23. A. Salahpour, S. Angers, J.F. Mercier, M. Lagace, S. Marullo, and M. Bouvier Homodimerization of the beta2-adrenergic receptor as a prerequisite for cell surface targeting J. Biol. Chem. 279 2004 33390 33397
24. A.A. Roy, K.E. Lemberg, and P. Chidiac Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions Mol. Pharmacol. 64 2003 587 593
25. P. Braun, M. Tasan, M. Dreze, M. Barrios-Rodiles, I. Lemmens, H. Yu, J.M. Sahalie, R.R. Murray, L. Roncari, A.S. de Smet, K. Venkatesan, J.F. Rual, J. Vandenhaute, M.E. Cusick, T. Pawson, D.E. Hill, J. Tavernier, J.L. Wrana, F.P. Roth, and M. Vidal An experimentally derived confidence score for binary protein-protein interactions Nat. Methods 6 2009 91 97
26. J. Dusonchet, J.C. Bensadoun, B.L. Schneider, and P. Aebischer Targeted overexpression of the parkin substrate Pael-R in the nigrostriatal system of adult rats to model Parkinson's disease Neurobiol. Dis. 35 2009 32 41
27. J.L. Moreno, S.C. Sealfon, and J. Gonzalez-Maeso Group II metabotropic glutamate receptors and schizophrenia Cell. Mol. Life Sci. 66 2009 3777 3785
28. J.D. Violin, L.M. DiPilato, N. Yildirim, T.C. Elston, J. Zhang, and R.J. Lefkowitz Beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics J. Biol. Chem. 283 2008 2949 2961
29. C.L. Reiner, J.S. McCullar, R.L. Kow, J.H. Le, D.R. Goodlett, and N.M. Nathanson RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking PLoS One 5 2010 e13517
30. K.R. Brown, and I. Jurisica Unequal evolutionary conservation of human protein interactions in interologous networks Genome Biol. 8 2007 R95
31. K.R. Brown, D. Otasek, M. Ali, M. McGuffin, W. Xie, B. Devani, I.L. Van Toch, and I. Jurisica NAViGaTOR: network analysis, visualization & graphing Toronto Bioinformatics 25 2009 3327 3329