Prothrombin complex concentrate safely reverses warfarin-related bleeding

Evidence-Based Medicine

Volumn 19, Issue 2, 2014, Pages 75-

  Tran, Huyen ^a   Chunilal, Sanjeev ^b  

^a ALFRED HOSPITAL   (Australia)

^b MONASH MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

FRESH FROZEN PLASMA; PROTHROMBIN COMPLEX; WARFARIN;

ANTICOAGULANT THERAPY; BLEEDING; BLOOD CLOTTING DISORDER; DRUG EFFICACY; DRUG SAFETY; ERYTHROCYTE TRANSFUSION; FATALITY; HUMAN; INTERNATIONAL NORMALIZED RATIO; NOTE; OUTCOME ASSESSMENT; THROMBOSIS; UNSPECIFIED SIDE EFFECT;

BLOOD COAGULATION FACTORS; FEMALE; HEMORRHAGE; HUMANS; MALE; PLASMA; THROMBOEMBOLISM; WARFARIN;

EID: 84897419923     PISSN: 13565524     EISSN: 14736810     Source Type: Journal    
DOI: 10.1136/eb-2013-101523     Document Type: Note

References (4)

1. Levi M, Hovingh K. Bleeding complications in patients on anticoagulants who would have been disqualified for clinical trials. Thromb Haemost 2008;100:1047-51.
2. Lubetsky A, Yonath H, Olchovsky D, et al . Comparison of oral vs intravenous phytonadione (vitamin K1) in patients with excessive anticoagulation: a prospective randomized controlled study. Arch Intern Med 2003;163:2469-73. (Pubitemid 37385789)
3. Goodnough LT, Shander A. How I treat warfarin-associated coagulopathy in patients with intracerebral hemorrhage. Blood 2011;117:6091-9.
4. Burbury KL, Milner A, Snooks B, et al. Short-term warfarin reversal for elective surgery - using low-dose intravenous vitamin K: safe, reliable and convenient. Br J Haematol 2011;154:626-34.