Genome-wide genotyping demonstrates a polygenic risk score associated with white matter hyperintensity volume in CADASIL

Stroke

Volumn 45, Issue 4, 2014, Pages 968-972

  Opherk, Christian ^a   Gonik, Mariya ^a   Duering, Marco ^a   Malik, Rainer ^a   Jouvent, Eric ^b   Hervé, Dominique ^c   Adib Samii, Poneh ^d   Bevan, Steve ^d   Pianese, Luigi ^h   Silvestri, Serena ^e   Dotti, Maria Teresa ^f   De Stefano, Nicola ^f   Liem, Michael ^g   Boon, Elles M J ^g   Pescini, Francesca ^h   Pachai, Chahin ⁱ   Bracoud, Luc ⁱ   Müller Myhsok, Bertram ^j   Meitinger, Thomas ^k   Rost, Natalia ^l   Pantoni, Leonardo ^e   Lesnik Oberstein, Saskia ^g   Federico, Antonio ^f   Ragno, Michele ^e   Markus, Hugh S ^m   Tournier Lasserve, Elisabeth ^c   Rosand, Jonathan ^l,n   Chabriat, Hugues ^b   Dichgans, Martin ^a,o   more..

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b HÔPITAL LARIBOISIÈRE   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^e Mazzoni Hospital   (Italy)

^f UNIVERSITY OF SIENA   (Italy)

^g LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^h CAREGGI UNIVERSITY HOSPITAL   (Italy)

ⁱ BioClinica Inc   (United States)

^j MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^k INSTITUTE OF EPIDEMIOLOGY   (Germany)

^l MASSACHUSETTS GENERAL HOSPITAL   (United States)

^m UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁿ BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^o Technische Universität München Munich Cluster for Systems Neurology   (Germany)

more..

Author keywords

CADASIL; Cerebral small vessel diseases; Genetics

Indexed keywords

ADULT; AGED; ARTICLE; BRAIN SIZE; CADASIL; EUROPE; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HERITABILITY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SINGLE NUCLEOTIDE POLYMORPHISM; WHITE MATTER; WHITE MATTER HYPERINTENSITY VOLUME; YOUNG ADULT;

CADASIL; CEREBRAL SMALL VESSEL DISEASES; GENETICS; GENOME-WIDE ASSOCIATION STUDY; LEUKOARAIOSIS;

ADULT; AGED; CADASIL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; HYPERTENSION; LEUKOENCEPHALOPATHIES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MODELS, GENETIC; QUANTITATIVE TRAIT LOCI; RISK FACTORS;

EID: 84897414534     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.004461     Document Type: Article

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