메뉴 건너뛰기




Volumn 41, Issue 4, 2014, Pages 666-672

Abatacept reduces levels of switched memory B cells, autoantibodies, and immunoglobulins in patients with rheumatoid arthritis

Author keywords

ABatacept; B lymphocytes; Free light chains anticitrullinated protein antibodies; Rheumatoid factor

Indexed keywords

ABATACEPT; ANTICITRULLINATED PROTEIN AUTOANTIBODY; AUTOANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; UNCLASSIFIED DRUG; ANTIBODY CONJUGATE; IMMUNOSUPPRESSIVE AGENT; RHEUMATOID FACTOR;

EID: 84897403943     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.130905     Document Type: Article
Times cited : (67)

References (37)
  • 1
    • 84855172814 scopus 로고    scopus 로고
    • The pathogenesis of rheumatoid arthritis
    • McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med 2011;365:2205-19.
    • (2011) N Engl J Med , vol.365 , pp. 2205-2219
    • McInnes, I.B.1    Schett, G.2
  • 2
    • 80855138676 scopus 로고    scopus 로고
    • B-cells and their targeting in rheumatoid arthritis - Current concepts and future perspectives
    • Nakken B, Munthe LA, Konttinen YT, Sandberg AK, Szekanecz Z, Alex P, et al. B-cells and their targeting in rheumatoid arthritis - current concepts and future perspectives. Autoimmun Rev 2011;11:28-34.
    • (2011) Autoimmun Rev , vol.11 , pp. 28-34
    • Nakken, B.1    Munthe, L.A.2    Konttinen, Y.T.3    Sandberg, A.K.4    Szekanecz, Z.5    Alex, P.6
  • 3
    • 33846001611 scopus 로고    scopus 로고
    • Serum immunoglobulin free light chain assessment in rheumatoid arthritis and primary sjogren's syndrome
    • Gottenberg JE, Aucouturier F, Goetz J, Sordet C, Jahn I, Busson M, et al. Serum immunoglobulin free light chain assessment in rheumatoid arthritis and primary Sjogren's syndrome. Ann Rheum Dis 2007;66:23-7.
    • (2007) Ann Rheum Dis , vol.66 , pp. 23-27
    • Gottenberg, J.E.1    Aucouturier, F.2    Goetz, J.3    Sordet, C.4    Jahn, I.5    Busson, M.6
  • 4
    • 0032476611 scopus 로고    scopus 로고
    • Human immunoglobulin (ig)m+igd+ peripheral blood b cells expressing the cd27 cell surface antigen carry somatically mutated variable region genes: Cd27 as a general marker for somatically mutated (memory) b cells
    • Klein U, Rajewsky K, Kuppers R. Human immunoglobulin (Ig)M+IgD+ peripheral blood B cells expressing the CD27 cell surface antigen carry somatically mutated variable region genes: CD27 as a general marker for somatically mutated (memory) B cells. J Exp Med 1998;188:1679-89.
    • (1998) J Exp Med , vol.188 , pp. 1679-1689
    • Klein, U.1    Rajewsky, K.2    Kuppers, R.3
  • 5
    • 34248140178 scopus 로고    scopus 로고
    • A new population of cells lacking expression of cd27 represents a notable component of the b cell memory compartment in systemic lupus erythematosus
    • Wei C, Anolik J, Cappione A, Zheng B, Pugh-Bernard A, Brooks J, et al. A new population of cells lacking expression of CD27 represents a notable component of the B cell memory compartment in systemic lupus erythematosus. J Immunol 2007;178:6624-33.
    • (2007) J Immunol , vol.178 , pp. 6624-6633
    • Wei, C.1    Anolik, J.2    Cappione, A.3    Zheng, B.4    Pugh-Bernard, A.5    Brooks, J.6
  • 6
    • 67649472564 scopus 로고    scopus 로고
    • Alterations in peripheral blood memory b cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor
    • Souto-Carneiro MM, Mahadevan V, Takada K, Fritsch-Stork R, Nanki T, Brown M, et al. Alterations in peripheral blood memory B cells in patients with active rheumatoid arthritis are dependent on the action of tumour necrosis factor. Arthritis Res Ther 2009;11:R84.
    • (2009) Arthritis Res Ther , vol.11
    • Souto-Carneiro, M.M.1    Mahadevan, V.2    Takada, K.3    Fritsch-Stork, R.4    Nanki, T.5    Brown, M.6
  • 7
    • 84858776729 scopus 로고    scopus 로고
    • B-cell subsets in the joint compartments of seropositive and seronegative rheumatoid arthritis (ra) and no-ra arthritides express memory markers and zap70 and characterize the aggregate pattern irrespectively of the autoantibody status
    • Michelutti A, Gremese E, Morassi F, Petricca L, Arena V, Tolusso B, et al. B-cell subsets in the joint compartments of seropositive and seronegative rheumatoid arthritis (RA) and no-RA arthritides express memory markers and ZAP70 and characterize the aggregate pattern irrespectively of the autoantibody status. Mol Med 2011;17:901-9.
    • (2011) Mol Med , vol.17 , pp. 901-909
    • Michelutti, A.1    Gremese, E.2    Morassi, F.3    Petricca, L.4    Arena, V.5    Tolusso, B.6
  • 8
    • 76649140079 scopus 로고    scopus 로고
    • Abatacept for rheumatoid arthritis: A cochrane systematic review
    • Maxwell LJ, Singh JA. Abatacept for rheumatoid arthritis: a Cochrane systematic review. J Rheumatol 2010;37:234-45.
    • (2010) J Rheumatol , vol.37 , pp. 234-245
    • Maxwell, L.J.1    Singh, J.A.2
  • 9
    • 84877819591 scopus 로고    scopus 로고
    • Advances in ctla-4-ig-mediated modulation of inflammatory cell and immune response activation in rheumatoid arthritis
    • Cutolo M, Nadler SG. Advances in CTLA-4-Ig-mediated modulation of inflammatory cell and immune response activation in rheumatoid arthritis. Autoimmun Rev 2013;12:758-67.
    • (2013) Autoimmun Rev , vol.12 , pp. 758-767
    • Cutolo, M.1    Nadler, S.G.2
  • 11
    • 67449116863 scopus 로고    scopus 로고
    • Validation of the 28-joint disease activity score (das28) and european league against rheumatism response criteria based on c-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the das28 based on erythrocyte sedimentation rate
    • Wells G, Becker J-C, Teng J, Dougados M, Schiff M, Smolen J, et al. Validation of the 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on C-reactive protein against disease progression in patients with rheumatoid arthritis, and comparison with the DAS28 based on erythrocyte sedimentation rate. Ann Rheum Dis 2009;68:954-60.
    • (2009) Ann Rheum Dis , vol.68 , pp. 954-960
    • Wells, G.1    Becker, J.-C.2    Teng, J.3    Dougados, M.4    Schiff, M.5    Smolen, J.6
  • 12
    • 0030035470 scopus 로고    scopus 로고
    • Consensus of a group of professional societies and diagnostic companies on guidelines for interim reference ranges for 14 proteins in serum based on the standardization against the ifcc/bcr/cap reference material (crm 470
    • Dati F, Schumann G, Thomas L, Aguzzi F, Baudner S, Bienvenu J, et al. Consensus of a group of professional societies and diagnostic companies on guidelines for interim reference ranges for 14 proteins in serum based on the standardization against the IFCC/BCR/CAP reference material (CRM 470). Eur J Clin Chem Clin Biochem 1996;34:517-20.
    • (1996) Eur J Clin Chem Clin Biochem , vol.34 , pp. 517-520
    • Dati, F.1    Schumann, G.2    Thomas, L.3    Aguzzi, F.4    Baudner, S.5    Bienvenu, J.6
  • 13
    • 0036720993 scopus 로고    scopus 로고
    • Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: Relative sensitivity for detection of monoclonal light chains
    • Katzmann JA, Clark RJ, Abraham RS, Bryant S, Lymp JF, Bradwell AR, et al. Serum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains. Clin Chem 2002;48:1437-44.
    • (2002) Clin Chem , vol.48 , pp. 1437-1444
    • Katzmann, J.A.1    Clark, R.J.2    Abraham, R.S.3    Bryant, S.4    Lymp, J.F.5    Bradwell, A.R.6
  • 15
    • 78649748637 scopus 로고    scopus 로고
    • Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-cd20) treatment correlates with decrease in disease activity
    • Kormelink TG, Tekstra J, Thurlings RM, Boumans MH, Vos K, Tak PP, et al. Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity. Ann Rheum Dis 2010;69:2137-44.
    • (2010) Ann Rheum Dis , vol.69 , pp. 2137-2144
    • Kormelink, T.G.1    Tekstra, J.2    Thurlings, R.M.3    Boumans, M.H.4    Vos, K.5    Tak, P.P.6
  • 16
    • 68649106906 scopus 로고    scopus 로고
    • Markers of b-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the espoir cohort
    • Gottenberg JE, Miceli-Richard C, Ducot B, Goupille P, Combe B, Mariette X. Markers of B-lymphocyte activation are elevated in patients with early rheumatoid arthritis and correlated with disease activity in the ESPOIR cohort. Arthritis Res Ther 2009;11:R114.
    • (2009) Arthritis Res Ther , vol.11
    • Gottenberg, J.E.1    Miceli-Richard, C.2    Ducot, B.3    Goupille, P.4    Combe, B.5    Mariette, X.6
  • 17
    • 79953711736 scopus 로고    scopus 로고
    • B cell activation biomarkers as predictive factors for the response to rituximab in rheumatoid arthritis
    • Sellam J, Hendel-Chavez H, Rouanet S, Abbed K, Combe B, Le Loët X, et al. B Cell activation biomarkers as predictive factors for the response to rituximab in rheumatoid arthritis. Arthritis Rheum 2011;63:933-8.
    • (2011) Arthritis Rheum , vol.63 , pp. 933-938
    • Sellam, J.1    Hendel-Chavez, H.2    Rouanet, S.3    Abbed, K.4    Combe, B.5    Le Loët, X.6
  • 18
    • 84867401801 scopus 로고    scopus 로고
    • Positivity for anti-cyclic citrullinated peptide is associated with a better response to abatacept: Data from the 'orencia and rheumatoid arthritis' registry
    • Gottenberg JE, Rayaud P, Cantagrel A, Combe B, Flipo RM, Schaeverbeke T, et al. Positivity for anti-cyclic citrullinated peptide is associated with a better response to abatacept: data from the 'Orencia and Rheumatoid Arthritis' registry. Ann Rheum Dis 2012;71:1815-9.
    • (2012) Ann Rheum Dis , vol.71 , pp. 9
    • Gottenberg, J.E.1    Rayaud, P.2    Cantagrel, A.3    Combe, B.4    Flipo, R.M.5    Schaeverbeke, T.6
  • 19
    • 84872088361 scopus 로고    scopus 로고
    • Serological changes in the course of traditional and biological disease modifying therapy of rheumatoid arthritis
    • Bohler C, Radner H, Smolen JS, Aletaha D. Serological changes in the course of traditional and biological disease modifying therapy of rheumatoid arthritis. Ann Rheum Dis 2013;72:241-4.
    • (2013) Ann Rheum Dis , vol.72 , pp. 241-244
    • Bohler, C.1    Radner, H.2    Smolen, J.S.3    Aletaha, D.4
  • 20
    • 1942440157 scopus 로고    scopus 로고
    • Decrease of anti-cyclic citrullinated peptide antibodies and rheumatoid factor following anti-tnfa therapy (infliximab) in rheumatoid arthritis is associated with clinical improvement
    • Alessandri C, Bombardieri M, Del Papa N, Cinquini M, Magrini L, Tincani A, et al. Decrease of anti-cyclic citrullinated peptide antibodies and rheumatoid factor following anti-TNFa therapy (infliximab) in rheumatoid arthritis is associated with clinical improvement. Ann Rheum Dis 2004;63:1218-21.
    • (2004) Ann Rheum Dis , vol.63 , pp. 1218-1221
    • Alessandri, C.1    Bombardieri, M.2    Del Papa, N.3    Cinquini, M.4    Magrini, L.5    Tincani, A.6
  • 21
    • 34147220774 scopus 로고    scopus 로고
    • High iga rheumatoid factor levels are associated with poor clinical response to tumour necrosis factor a inhibitors in rheumatoid arthritis
    • Bobbio-Pallavicini F, Caporali R, Alpini C, Avalle S, Epis OM, Klersy C, et al. High IgA rheumatoid factor levels are associated with poor clinical response to tumour necrosis factor a inhibitors in rheumatoid arthritis. Ann Rheum Dis 2007;66:302-7.
    • (2007) Ann Rheum Dis , vol.66 , pp. 302-307
    • Bobbio-Pallavicini, F.1    Caporali, R.2    Alpini, C.3    Avalle, S.4    Epis, O.M.5    Klersy, C.6
  • 22
    • 67349090358 scopus 로고    scopus 로고
    • Adalimumab clinical efficacy is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibody titer reduction: A one-year prospective study
    • Atzeni F, Sarzi-Puttini P, Dell'Acqua D, de Portu S, Cecchini G, Cruini C, et al. Adalimumab clinical efficacy is associated with rheumatoid factor and anti-cyclic citrullinated peptide antibody titer reduction: a one-year prospective study. Arthritis Res Ther 2006;8:R3.
    • (2006) Arthritis Res Ther , vol.8
    • Atzeni, F.1    Sarzi-Puttini, P.2    Dell'Acqua, D.3    De Portu, S.4    Cecchini, G.5    Cruini, C.6
  • 23
    • 29144519684 scopus 로고    scopus 로고
    • The effect of etanercept on anti-cyclic citrullinated peptide antibodies and rheumatoid factor in patients with rheumatoid arthritis
    • Chen HA, Lin KC, Chen CH, Liao HT, Wang HP, Chang HN, et al. The effect of etanercept on anti-cyclic citrullinated peptide antibodies and rheumatoid factor in patients with rheumatoid arthritis. Ann Rheum Dis 2006;65:35-9.
    • (2006) Ann Rheum Dis , vol.65 , pp. 35-39
    • Chen, H.A.1    Lin, K.C.2    Chen, C.H.3    Liao, H.T.4    Wang, H.P.5    Chang, H.N.6
  • 24
    • 13244261140 scopus 로고    scopus 로고
    • Rheumatoid factor, but not anti-cyclic citrullinated peptide antibodies, is modulated by infliximab treatment in rheumatoid arthritis
    • De Rycke L, Verhelst X, Kruithof E, Van den Bosch F, Hoffman IE, Veys EM, et al. Rheumatoid factor, but not anti-cyclic citrullinated peptide antibodies, is modulated by infliximab treatment in rheumatoid arthritis. Ann Rheum Dis 2005;64:299-302.
    • (2005) Ann Rheum Dis , vol.64 , pp. 299-302
    • De Rycke, L.1    Verhelst, X.2    Kruithof, E.3    Van Den Bosch, F.4    Hoffman, I.E.5    Veys, E.M.6
  • 26
    • 38149044612 scopus 로고    scopus 로고
    • Synovial tissue response - Rituximab: Mechanism of action and identification of biomarkers of response
    • Thurlings RM, Vos K, Wijbrandts CA, Zwinderman AH, Gerlag DM, Tak PP. Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response. Ann Rheum Dis 2008;67:917-25.
    • (2008) Ann Rheum Dis , vol.67 , pp. 917-925
    • Thurlings, R.M.1    Vos, K.2    Wijbrandts, C.A.3    Zwinderman, A.H.4    Gerlag, D.M.5    Tak, P.P.6
  • 27
    • 65949099716 scopus 로고    scopus 로고
    • Class-switched b cells display response to therapeutic b-cell depletion in rheumatoid arthritis
    • Moller B, Aeberli D, Eggli S, Fuhrer M, Vajtai I, Vögelin E, et al. Class-switched B cells display response to therapeutic B-cell depletion in rheumatoid arthritis. Arthritis Res Ther 2009;11:R62.
    • (2009) Arthritis Res Ther , vol.11
    • Moller, B.1    Aeberli, D.2    Eggli, S.3    Fuhrer, M.4    Vajtai, I.5    Vögelin, E.6
  • 28
    • 67549119579 scopus 로고    scopus 로고
    • Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: A histological, gene expression and dynamic magnetic resonance imaging pilot study
    • Buch MH, Boyle DL, Rosengren S, Saleem B, Reece RJ, Rhodes LA, et al. Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study. Ann Rheum Dis 2009;68:1220-7.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1220-1227
    • Buch, M.H.1    Boyle, D.L.2    Rosengren, S.3    Saleem, B.4    Reece, R.J.5    Rhodes, L.A.6
  • 29
    • 84879693915 scopus 로고    scopus 로고
    • Immunohistological analysis of synovium treated with abatacept in rheumatoid arthritis
    • Kanbe K, Chiba J, Nakamura A. Immunohistological analysis of synovium treated with abatacept in rheumatoid arthritis. Rheumatol Int 2013;33:1883-7.
    • (2013) Rheumatol Int , vol.33 , pp. 7
    • Kanbe, K.1    Chiba, J.2    Nakamura, A.3
  • 30
    • 84871033136 scopus 로고    scopus 로고
    • Forget personalized medicine and focus on abating disease activity
    • Smolen JS, Aletaha D. Forget personalized medicine and focus on abating disease activity. Ann Rheum Dis 2013;72:3-6.
    • (2013) Ann Rheum Dis , vol.72 , pp. 3-6
    • Smolen, J.S.1    Aletaha, D.2
  • 31
    • 77956410939 scopus 로고    scopus 로고
    • Abatacept limits breach of self-tolerance in a murine model of arthritis via effects on the generation of t follicular helper cells
    • Platt AM, Gibson VB, Patakas A, Benson RA, Nadler SG, Brewer JM, et al. Abatacept limits breach of self-tolerance in a murine model of arthritis via effects on the generation of T follicular helper cells. J Immunol 2010;185:1558-67.
    • (2010) J Immunol , vol.185 , pp. 1558-1567
    • Platt, A.M.1    Gibson, V.B.2    Patakas, A.3    Benson, R.A.4    Nadler, S.G.5    Brewer, J.M.6
  • 32
    • 84861799713 scopus 로고    scopus 로고
    • T cell lessons from the rheumatoid arthritis synovium scid mouse model: Cd3-rich synovium lacks response to ctla-4ig but is successfully treated by interleukin-17 neutralization
    • Koenders MI, Marijnissen RJ, Joosten LA, Abdollahi-Roodsaz S, Di Padova FE, van de Loo FA, et al. T cell lessons from the rheumatoid arthritis synovium SCID mouse model: CD3-rich synovium lacks response to CTLA-4Ig but is successfully treated by interleukin-17 neutralization. Arthritis Rheum 2012;64:1762-70.
    • (2012) Arthritis Rheum , vol.64 , pp. 1762-1770
    • Koenders, M.I.1    Marijnissen, R.J.2    Joosten, L.A.3    Abdollahi-Roodsaz, S.4    Di Padova, F.E.5    Van De Loo, F.A.6
  • 33
    • 77951785328 scopus 로고    scopus 로고
    • Decreased circulating cd28-negative t cells in patients with rheumatoid arthritis treated with abatacept are correlated with clinical response
    • Scarsi M, Ziglioli T, Airò P. Decreased circulating CD28-negative T cells in patients with rheumatoid arthritis treated with abatacept are correlated with clinical response. J Rheumatol 2010;37:911-6.
    • (2010) J Rheumatol , vol.37 , pp. 911-916
    • Scarsi, M.1    Ziglioli, T.2    Airò, P.3
  • 34
    • 84871712547 scopus 로고    scopus 로고
    • Targeting cd4+cd28- t cells by blocking cd28 co-stimulation
    • Airò P, Scarsi M. Targeting CD4+CD28- T cells by blocking CD28 co-stimulation. Trends Mol Med 2013;19:1-2.
    • (2013) Trends Mol Med , vol.19 , pp. 1-2
    • Airò, P.1    Scarsi, M.2
  • 35
    • 84876323608 scopus 로고    scopus 로고
    • Abatacept and reduced immune response to pandemic 2009 influenza a/h1n1 vaccination in patients with rheumatoid arthritis
    • Ribeiro AC, Laurindo IM, Guedes LK, Saad CG, Moraes JC, Silva CA, et al. Abatacept and reduced immune response to pandemic 2009 influenza A/H1N1 vaccination in patients with rheumatoid arthritis. Arthritis Care Res 2013;65:476-80.
    • (2013) Arthritis Care Res , vol.65 , pp. 476-480
    • Ribeiro, A.C.1    Laurindo, I.M.2    Guedes, L.K.3    Saad, C.G.4    Moraes, J.C.5    Silva, C.A.6
  • 36
    • 84858639592 scopus 로고    scopus 로고
    • Protective effect of a/h1n1 vaccination in immune-mediated disease - A prospectively controlled vaccination study
    • Adler S, Krivine A, Weix J, Rozenberg F, Launay O, Huesler J, et al. Protective effect of A/H1N1 vaccination in immune-mediated disease - a prospectively controlled vaccination study. Rheumatology 2012;51:695-700.
    • (2012) Rheumatology , vol.51 , pp. 695-700
    • Adler, S.1    Krivine, A.2    Weix, J.3    Rozenberg, F.4    Launay, O.5    Huesler, J.6
  • 37
    • 84878631800 scopus 로고    scopus 로고
    • Safety of abatacept administered intravenously in treatment of rheumatoid arthritis: Integrated analyses of up to 8 years of treatment from the abatacept clinical trial program
    • Weinblatt ME, Moreland LW, Westhovens R, Cohen RB, Kelly SM, Khan N, et al. Safety of abatacept administered intravenously in treatment of rheumatoid arthritis: integrated analyses of up to 8 years of treatment from the abatacept clinical trial program. J Rheumatol 2013;40:787-97.
    • (2013) J Rheumatol , vol.40 , pp. 787-797
    • Weinblatt, M.E.1    Moreland, L.W.2    Westhovens, R.3    Cohen, R.B.4    Kelly, S.M.5    Khan, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.