Combination treatment with N-acetyl-seryl-aspartyl-lysyl-proline and tissue plasminogen activator provides potent neuroprotection in rats after stroke

Stroke

Volumn 45, Issue 4, 2014, Pages 1108-1114

  Zhang, Li ^a   Chopp, Michael ^a,c   Teng, Hua ^a   Ding, Guangliang ^a   Jiang, Quan ^a   Yang, Xiao Ping ^b   Rhaleb, Nour Eddine ^b   Zhang, Zheng Gang ^a  

^a HENRY FORD HOSPITAL   (United States)

^b HENRY FORD HEALTH SCIENCES CENTER   (United States)

^c OAKLAND UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; FIBRIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; SERASPENIDE; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD VESSEL PERMEABILITY; BRAIN BLOOD VESSEL; BRAIN HEMORRHAGE; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CAPILLARY PERMEABILITY; CEREBROSPINAL FLUID; CEREBROVASCULAR ACCIDENT; CONTROLLED STUDY; ENZYME IMMUNOASSAY; FIBRINOLYTIC THERAPY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MICROVASCULAR ENDOTHELIAL CELL; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; THROMBOCYTE;

CAPILLARY PERMEABILITY; ISCHEMIA; STROKE;

ANIMALS; BLOOD-BRAIN BARRIER; DISEASE MODELS, ANIMAL; DRUG THERAPY, COMBINATION; ENDOTHELIAL CELLS; FIBRINOLYTIC AGENTS; GROWTH INHIBITORS; HUMANS; INTRACRANIAL EMBOLISM; MAGNETIC RESONANCE IMAGING; MALE; NEUROPROTECTIVE AGENTS; NF-KAPPA B; OLIGOPEPTIDES; PLASMINOGEN ACTIVATOR INHIBITOR 1; PRIMARY CELL CULTURE; RATS; RATS, WISTAR; STROKE; TISSUE PLASMINOGEN ACTIVATOR; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84897372521     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.113.004399     Document Type: Article

References (0)