Prdm12 is induced by retinoic acid and exhibits anti-proliferative properties through the cell cycle modulation of P19 embryonic carcinoma cells

Cell Structure and Function

Volumn 38, Issue 2, 2013, Pages 195-204

  Yang, Chia Ming ^a   Shinkai, Yoichi ^b  

^a KYOTO UNIVERSITY   (Japan)

^b RIKEN   (Japan)

Author keywords

Cell cycle; Histone methyltransferase; Prdm12; Retinoic acid

Indexed keywords

B LYMPHOCYTE INDUCED MATURATION PROTEIN 1; HISTONE H3; LYSINE; PROTEIN P27; PROTEIN PRDM12; RETINOIC ACID; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; CARRIER PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; NERVE PROTEIN; PRDM12 PROTEIN, HUMAN; PRDM12 PROTEIN, MOUSE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

ANIMAL CELL; ARTICLE; CANCER CELL CULTURE; CELL CYCLE; CELL CYCLE G1 PHASE; CELL DIFFERENTIATION; CELL GROWTH; CELL POPULATION; CONTROLLED STUDY; EMBRYONAL CARCINOMA STEM CELL; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; P19 CELL LINE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; 3T3 CELL LINE; ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; CYTOLOGY; EMBRYOLOGY; GENETICS; HEK293 CELL LINE; METABOLISM; METHYLATION; NERVOUS SYSTEM; RNA INTERFERENCE; TUMOR CELL LINE;

ANIMALIA;

3T3 CELLS; ANIMALS; CARRIER PROTEINS; CELL CYCLE; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P27; EMBRYONAL CARCINOMA STEM CELLS; HEK293 CELLS; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HUMANS; METHYLATION; MICE; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; NEUROGENESIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRETINOIN; ZINC FINGERS;

EID: 84897364620     PISSN: 03867196     EISSN: 13473700     Source Type: Journal    
DOI: 10.1247/csf.13010     Document Type: Article

References (24)

1. Chia, N.Y., Chan, Y.S., Feng, B., Lu, X., Orlov, Y.L., Moreau, D., Kumar, P., Yang, L., Jiang, J., Lau, M.S., Huss, M., Soh, B.S., Kraus, P., Li, P., Lufkin, T., Lim, B., Clarke, N.D., Bard, F., and Ng, H.H. 2010. A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity. Nature, 468: 316-320.
2. Chittka, A., Arevalo, J.C., Rodriguez-Guzman, M., Perez, P., Chao, M.V., and Sendtner, M. 2004. The p75NTR-interacting protein SC1 inhibits cell cycle progression by transcriptional repression of cyclin E. J. Cell Biol., 164: 985-996.
3. Corcoran, J., Shroot, B., Pizzey, J., and Maden, M. 2000. The role of retinoic acid receptors in neurite outgrowth from different populations of embryonic mouse dorsal root ganglia. J. Cell Sci., 113(Pt14): 2567-2574.
4. Fog, C.K., Galli, G.G., and Lund, A.H. 2012. PRDM proteins: important players in differentiation and disease. Bioessays, 34: 50-60.
5. Gill, R.M., Slack, R., Kiess, M., and Hamel, P.A. 1998. Regulation of expression and activity of distinct pRB, E2F, D-type cyclin, and CKI family members during terminal differentiation of P19 cells. Exp. Cell Res., 244: 157-170.
6. Gyory, I., Wu, J., Fejer, G., Seto, E., and Wright, K.L. 2004. PRDI-BF1 recruits the histone H3 methyltransferase G9a in transcriptional silencing. Nat. Immunol., 5: 299-308.
7. Hernandez-Lagunas, L., Choi, I.F., Kaji, T., Simpson, P., Hershey, C., Zhou, Y., Zon, L., Mercola, M., and Artinger, K.B. 2005. Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification. Dev. Biol., 278: 347-357.
8. Hohenauer, T. and Moore, A.W. 2012. The Prdm family: expanding roles in stem cells and development. Development, 139: 2267-2282.
9. Jones-Villeneuve, E.M., McBurney, M.W., Rogers, K.A., and Kalnins, V.I. 1982. Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells. J. Cell Biol., 94: 253-262.
10. Katoh, K., Yamazaki, R., Onishi, A., Sanuki, R., and Furukawa, T. 2012. G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells. J Neurosci., 32: 17658-17670.
11. Kinameri, E., Inoue, T., Aruga, J., Imayoshi, I., Kageyama, R., Shimogori, T., and Moore, A.W. 2008. Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS ONE, 3: e3859.
12. Komai, T., Iwanari, H., Mochizuki, Y., Hamakubo, T., and Shinkai, Y. 2009. Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Gene Expr. Patterns, 9: 503-514.
13. Kranenburg, O., Scharnhorst, V., Van der Eb, A.J., and Zantema, A. 1995. Inhibition of cyclin-dependent kinase activity triggers neuronal differentiation of mouse neuroblastoma cells. J. Cell Biol., 131: 227-234.
14. Liu, C., Ma, W., Su, W., and Zhang, J. 2012. Prdm14 acts upstream of islet2 transcription to regulate axon growth of primary motoneurons in zebrafish. Development, 139: 4591-4600.
15. Maden, M. 2007. Retinoic acid in the development, regeneration and maintenance of the nervous system. Nat. Rev. Neurosci., 8: 755-765.
16. Pao, P.C., Huang, N.K., Liu, Y.W., Yeh, S.H., Lin, S.T., Hsieh, C.P., Huang, A.M., Huang, H.S., Tseng, J.T., Chang, W.C., and Lee, Y.C. 2011. A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells. Cell Death Differ., 18: 1791-1804.
17. Ross, S.E., McCord, A.E., Jung, C., Atan, D., Mok, S.I., Hemberg, M., Kim, T.K., Salogiannis, J., Hu, L., Cohen, S., Lin, Y., Harrar, D., McInnes, R.R., and Greenberg, M.E. 2012. Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron, 73: 292-303.
18. Sasaki, K., Tamura, S., Tachibana, H., Sugita, M., Gao, Y., Furuyama, J., Kakishita, E., Sakai, T., Tamaoki, T., and Hashimoto-Tamaoki, T. 2000. Expression and role of p27(kip1) in neuronal differentiation of embryonal carcinoma cells. Brain Res. Mol. Brain Res., 77: 209-221.
19. Sun, X.J., Xu, P.F., Zhou, T., Hu, M., Fu, C.T., Zhang, Y., Jin, Y., Chen, Y., Chen, S.J., Huang, Q.H., Liu, T.X., and Chen, Z. 2008. Genomewide survey and developmental expression mapping of zebrafish SET domain-containing genes. PLoS ONE, 3: e1499.
20. Tachibana, M., Sugimoto, K., Fukushima, T., and Shinkai, Y. 2001. Set domain-containing protein, G9a, is a novel lysine-preferring mammalian histone methyltransferase with hyperactivity and specific selectivity to lysines 9 and 27 of histone H3. J. Biol. Chem., 276: 25309-25317.
21. Tachibana, M., Sugimoto, K., Nozaki, M., Ueda, J., Ohta, T., Ohki, M., Fukuda, M., Takeda, N., Niida, H., Kato, H., and Shinkai, Y. 2002. G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis. Genes Dev., 16: 1779-1791.
22. Tsuneyoshi, N., Sumi, T., Onda, H., Nojima, H., Nakatsuji, N., and Suemori, H. 2008. PRDM14 suppresses expression of differentiation marker genes in human embryonic stem cells. Biochem. Biophys. Res. Commun., 367: 899-905.
23. Völkel, P. and Angrand, P.O. 2007. The control of histone lysine methylation in epigenetic regulation. Biochimie, 89: 1-20.
24. Wong, L.F., Yip, P.K., Battaglia, A., Grist, J., Corcoran, J., Maden, M., Azzouz, M., Kingsman, S.M., Kingsman, A.J., Mazarakis, N.D., and McMahon, S.B. 2006. Retinoic acid receptor beta2 promotes functional regeneration of sensory axons in the spinal cord. Nat. Neurosci., 9: 243-250.