-
1
-
-
0036956424
-
Protein kinase C-epsilon (PKC-epsilon): Its unique structure and function
-
Akita Y (2002) Protein kinase C-epsilon (PKC-epsilon): its unique structure and function. J Biochem 132(6):847-852
-
(2002)
J Biochem
, vol.132
, Issue.6
, pp. 847-852
-
-
Akita, Y.1
-
2
-
-
79960542143
-
The mechanistic basis for the induction of hepatic steatosis by xenobiotics
-
Amacher DE (2011a) The mechanistic basis for the induction of hepatic steatosis by xenobiotics. Expert Opin Drug Metab Toxicol 7(8):949-965
-
(2011)
Expert Opin Drug Metab Toxicol
, vol.7
, Issue.8
, pp. 949-965
-
-
Amacher, D.E.1
-
3
-
-
78650018055
-
Strategies for the early detection of drug-induced hepatic steatosis in preclinical drug safety evaluation studies
-
Amacher DE (2011b) Strategies for the early detection of drug-induced hepatic steatosis in preclinical drug safety evaluation studies. Toxicology 279(1-3):10-18
-
(2011)
Toxicology
, vol.279
, Issue.1-3
, pp. 10-18
-
-
Amacher, D.E.1
-
4
-
-
0024461867
-
Alcoholic-like liver lesions induced by nifedipine
-
Babany G, Uzzan F, Larrey D et al (1989) Alcoholic-like liver lesions induced by nifedipine. J Hepatol 9(2):252-255 (Pubitemid 19224217)
-
(1989)
Journal of Hepatology
, vol.9
, Issue.2
, pp. 252-255
-
-
Babany, G.1
Uzzan, F.2
Larrey, D.3
Degott, C.4
Bourgeois, P.5
Rene, E.6
Vissuzaine, C.7
Erlinger, S.8
Benhamou, J.-P.9
-
5
-
-
0032410542
-
Binding of nonsteroidal antiinflammatory drugs to the alpha-subunit of the trifunctional protein of long chain fatty acid oxidation
-
Baldwin GS, Murphy VJ, Yang Z, Hashimoto T (1998) Binding of nonsteroidal antiinflammatory drugs to the alpha-subunit of the trifunctional protein of long chain fatty acid oxidation. J Pharmacol Exp Ther 286(2):1110-1114 (Pubitemid 29003510)
-
(1998)
Journal of Pharmacology and Experimental Therapeutics
, vol.286
, Issue.2
, pp. 1110-1114
-
-
Baldwin, G.S.1
Murphy, V.J.2
Yang, Z.3
Hashimoto, T.4
-
6
-
-
79952702137
-
Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver
-
Begriche K, Massart J, Robin MA, Borgne-Sanchez A, Fromenty B (2011) Drug-induced toxicity on mitochondria and lipid metabolism: mechanistic diversity and deleterious consequences for the liver. J Hepatol 54(4):773-794
-
(2011)
J Hepatol
, vol.54
, Issue.4
, pp. 773-794
-
-
Begriche, K.1
Massart, J.2
Robin, M.A.3
Borgne-Sanchez, A.4
Fromenty, B.5
-
7
-
-
0036145372
-
Toxicological consequences of altered peroxisome proliferator-activated receptor gamma (PPARgamma) expression in the liver: Insights from models of obesity and type 2 diabetes
-
DOI 10.1016/S0006-2952(01)00817-6, PII S0006295201008176
-
Boelsterli UA, Bedoucha M (2002) Toxicological consequences of altered peroxisome proliferator-activated receptor gamma (PPARgamma) expression in the liver: insights from models of obesity and type 2 diabetes. Biochem Pharmacol 63(1):1-10 (Pubitemid 34075287)
-
(2002)
Biochemical Pharmacology
, vol.63
, Issue.1
, pp. 1-10
-
-
Boelsterli, U.A.1
Bedoucha, M.2
-
9
-
-
79959517565
-
Human fatty liver disease: Old questions and new insights
-
Cohen JC, Horton JD, Hobbs H (2011) Human fatty liver disease: old questions and new insights. Science 332(6037):1519-1523
-
(2011)
Science
, vol.332
, Issue.6037
, pp. 1519-1523
-
-
Cohen, J.C.1
Horton, J.D.2
Hobbs, H.3
-
10
-
-
0345017786
-
Transcription Factors in Liver Development, Differentiation, and Regeneration
-
DOI 10.1016/j.hep.2003.09.034
-
Costa RH, Kalinichenko VV, Holterman AX, Wang X (2003) Transcription factors in liver development, differentiation, and regeneration. Hepatology 38(6):1331-1347 (Pubitemid 37466956)
-
(2003)
Hepatology
, vol.38
, Issue.6
, pp. 1331-1347
-
-
Costa, R.H.1
Kalinichenko, V.V.2
Holterman, A.-X.L.3
Wang, X.4
-
11
-
-
33645863768
-
Transcriptional regulation of metabolism
-
Desvergne B, Michalik L, Wahli W (2006) Transcriptional regulation of metabolism. Physiol Rev 86(2):465-514
-
(2006)
Physiol Rev
, vol.86
, Issue.2
, pp. 465-514
-
-
Desvergne, B.1
Michalik, L.2
Wahli, W.3
-
12
-
-
84868026974
-
Drug-induced liver steatosis and phospholipidosis: Cell-based assays for early screening of drug candidates
-
Donato MT, Gomez-Lechon MJ (2012) Drug-induced liver steatosis and phospholipidosis: cell-based assays for early screening of drug candidates. Curr Drug Metab 13(8):1160-1173
-
(2012)
Curr Drug Metab
, vol.13
, Issue.8
, pp. 1160-1173
-
-
Donato, M.T.1
Gomez-Lechon, M.J.2
-
13
-
-
70249107777
-
Cytometric analysis for drug-induced steatosis in HepG2 cells
-
Donato MT, Martinez-Romero A, Jimenez N et al (2009) Cytometric analysis for drug-induced steatosis in HepG2 cells. Chem Biol Interact 181(3):417-423
-
(2009)
Chem Biol Interact
, vol.181
, Issue.3
, pp. 417-423
-
-
Donato, M.T.1
Martinez-Romero, A.2
Jimenez, N.3
-
14
-
-
84859057446
-
High-content imaging technology for the evaluation of drug-induced steatosis using a multiparametric cell-based assay
-
Donato MT, Tolosa L, Jimenez N, Castell JV, Gomez-Lechon MJ (2012) High-content imaging technology for the evaluation of drug-induced steatosis using a multiparametric cell-based assay. J Biomol Screen 17(3):394-400
-
(2012)
J Biomol Screen
, vol.17
, Issue.3
, pp. 394-400
-
-
Donato, M.T.1
Tolosa, L.2
Jimenez, N.3
Castell, J.V.4
Gomez-Lechon, M.J.5
-
15
-
-
0034827301
-
Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes
-
Drocourt L, Pascussi JM, Assenat E, Fabre JM, Maurel P, Vilarem MJ (2001) Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes. Drug Metab Dispos 29(10):1325-1331 (Pubitemid 32896582)
-
(2001)
Drug Metabolism and Disposition
, vol.29
, Issue.10
, pp. 1325-1331
-
-
Drocourt, L.1
Pascussi, J.-M.2
Assenat, E.3
Fabre, J.-M.4
Maurel, P.5
Vilarem, M.-J.6
-
16
-
-
33644547706
-
Nonalcoholic fatty liver disease: From steatosis to cirrhosis
-
Farrell GC, Larter CZ (2006) Nonalcoholic fatty liver disease: from steatosis to cirrhosis. Hepatology 43(2 Suppl 1):S99-S112
-
(2006)
Hepatology
, vol.43
, Issue.2 SUPPL. 1
-
-
Farrell, G.C.1
Larter, C.Z.2
-
17
-
-
0025250709
-
Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids
-
Freneaux E, Fromenty B, Berson A et al (1990) Stereoselective and nonstereoselective effects of ibuprofen enantiomers on mitochondrial beta-oxidation of fatty acids. J Pharmacol Exp Ther 255(2):529-535
-
(1990)
J Pharmacol Exp Ther
, vol.255
, Issue.2
, pp. 529-535
-
-
Freneaux, E.1
Fromenty, B.2
Berson, A.3
-
18
-
-
0029127584
-
Inhibition of mitochondrial betaoxidation as a mechanism of hepatotoxicity
-
Fromenty B, Pessayre D (1995) Inhibition of mitochondrial betaoxidation as a mechanism of hepatotoxicity. Pharmacol Ther 67(1):101-154
-
(1995)
Pharmacol Ther
, vol.67
, Issue.1
, pp. 101-154
-
-
Fromenty, B.1
Pessayre, D.2
-
19
-
-
65649112138
-
In vitro assay for drug-induced hepatosteatosis using rat primary hepatocytes, a fluorescent lipid analog and gene expression analysis
-
Fujimura H, Murakami N, Kurabe M, Toriumi W (2009) In vitro assay for drug-induced hepatosteatosis using rat primary hepatocytes, a fluorescent lipid analog and gene expression analysis. J Appl Toxicol 29(4):356-363
-
(2009)
J Appl Toxicol
, vol.29
, Issue.4
, pp. 356-363
-
-
Fujimura, H.1
Murakami, N.2
Kurabe, M.3
Toriumi, W.4
-
20
-
-
0033983457
-
Subacute hepatic failure associated with a new antidiabetic agent, troglitazone: A case report with autopsy examination
-
Fukano M, Amano S, Sato J et al (2000) Subacute hepatic failure associated with a new antidiabetic agent, troglitazone: a case report with autopsy examination. Hum Pathol 31(2):250-253 (Pubitemid 30090658)
-
(2000)
Human Pathology
, vol.31
, Issue.2
, pp. 250-253
-
-
Fukano, M.1
Amano, S.2
Sato, J.3
Yamamoto, K.4
Adachi, H.5
Okabe, H.6
Fujiyama, Y.7
Bamba, T.8
-
21
-
-
77957021236
-
Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project
-
Gomez-Lechon MJ, Tolosa L, Castell JV, Donato MT (2010) Mechanism-based selection of compounds for the development of innovative in vitro approaches to hepatotoxicity studies in the LIINTOP project. Toxicol in Vitro 24(7):1879-1889
-
(2010)
Toxicol in Vitro
, vol.24
, Issue.7
, pp. 1879-1889
-
-
Gomez-Lechon, M.J.1
Tolosa, L.2
Castell, J.V.3
Donato, M.T.4
-
22
-
-
79955053506
-
Sry-box (Sox) transcription factors in gastrointestinal physiology and disease
-
Gracz AD, Magness ST (2011) Sry-box (Sox) transcription factors in gastrointestinal physiology and disease. Am J Physiol Gastrointest Liver Physiol 300(4):G503-G515
-
(2011)
Am J Physiol Gastrointest Liver Physiol
, vol.300
, Issue.4
-
-
Gracz, A.D.1
Magness, S.T.2
-
23
-
-
25844445911
-
Fatty liver and drugs
-
Grieco A, Forgione A, Miele L et al (2005) Fatty liver and drugs. Eur Rev Med Pharmacol Sci 9(5):261-263 (Pubitemid 41387388)
-
(2005)
European Review for Medical and Pharmacological Sciences
, vol.9
, Issue.5
, pp. 261-263
-
-
Grieco, A.1
Forgione, A.2
Miele, L.3
Vero, V.4
Greco, A.V.5
Gasbarrini, A.6
Gasbarrini, G.7
-
24
-
-
84872335543
-
An overview of transcriptional regulation in response to toxicological insult
-
Jennings P, Limonciel A, Felice L, Leonard MO (2013) An overview of transcriptional regulation in response to toxicological insult. Arch Toxicol 87(1):49-72
-
(2013)
Arch Toxicol
, vol.87
, Issue.1
, pp. 49-72
-
-
Jennings, P.1
Limonciel, A.2
Felice, L.3
Leonard, M.O.4
-
25
-
-
0033678859
-
Troglitazone prevents fatty changes of the liver in obese diabetic rats
-
Jia DM, Tabaru A, Akiyama T, Abe S, Otsuki M (2000) Troglitazone prevents fatty changes of the liver in obese diabetic rats. J Gastroenterol Hepatol 15(10):1183-1191
-
(2000)
J Gastroenterol Hepatol
, vol.15
, Issue.10
, pp. 1183-1191
-
-
Jia, D.M.1
Tabaru, A.2
Akiyama, T.3
Abe, S.4
Otsuki, M.5
-
26
-
-
0026515929
-
Evaluation of the cytotoxicity of ten chemicals on human cultured hepatocytes: Predictability of human toxicity and comparison with rodent cell culture systems
-
Jover R, Ponsoda X, Castell JV, Gomez-Lechon MJ (1992) Evaluation of the cytotoxicity of ten chemicals on human cultured hepatocytes: predictability of human toxicity and comparison with rodent cell culture systems. Toxicol In Vitro 6(1):47-52
-
(1992)
Toxicol in Vitro
, vol.6
, Issue.1
, pp. 47-52
-
-
Jover, R.1
Ponsoda, X.2
Castell, J.V.3
Gomez-Lechon, M.J.4
-
27
-
-
0036623233
-
Nuclear receptor regulation of hepatic function
-
Karpen SJ (2002) Nuclear receptor regulation of hepatic function. J Hepatol 36(6):832-850
-
(2002)
J Hepatol
, vol.36
, Issue.6
, pp. 832-850
-
-
Karpen, S.J.1
-
28
-
-
56049089150
-
Role of hepatic STAT3 in the regulation of lipid metabolism
-
Kinoshita S, Ogawa W, Okamoto Y et al (2008) Role of hepatic STAT3 in the regulation of lipid metabolism. Kobe J Med Sci 54(4):E200-E208
-
(2008)
Kobe J Med Sci
, vol.54
, Issue.4
-
-
Kinoshita, S.1
Ogawa, W.2
Okamoto, Y.3
-
29
-
-
60349084474
-
Activation of PPARalpha and PPARgamma reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1
-
Konig B, Koch A, Spielmann J et al (2009) Activation of PPARalpha and PPARgamma reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1. Eur J Pharmacol 605(1-3):23-30
-
(2009)
Eur J Pharmacol
, vol.605
, Issue.1-3
, pp. 23-30
-
-
Konig, B.1
Koch, A.2
Spielmann, J.3
-
30
-
-
55949124005
-
Drug-induced liver injury through mitochondrial dysfunction: Mechanisms and detection during preclinical safety studies
-
Labbe G, Pessayre D, Fromenty B (2008) Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies. Fundam Clin Pharmacol 22(4):335-353
-
(2008)
Fundam Clin Pharmacol
, vol.22
, Issue.4
, pp. 335-353
-
-
Labbe, G.1
Pessayre, D.2
Fromenty, B.3
-
31
-
-
84864104444
-
A myriad of pathways to NASH
-
Larrain S, Rinella ME (2012) A myriad of pathways to NASH. Clin Liver Dis 16(3):525-548
-
(2012)
Clin Liver Dis
, vol.16
, Issue.3
, pp. 525-548
-
-
Larrain, S.1
Rinella, M.E.2
-
32
-
-
33947224232
-
Gene expression profiles of murine fatty liver induced by the administration of valproic acid
-
DOI 10.1016/j.taap.2006.12.016, PII S0041008X0600487X
-
Lee MH, Hong I, Kim M et al (2007) Gene expression profiles of murine fatty liver induced by the administration of valproic acid. Toxicol Appl Pharmacol 220(1):45-59 (Pubitemid 46427862)
-
(2007)
Toxicology and Applied Pharmacology
, vol.220
, Issue.1
, pp. 45-59
-
-
Lee, M.-H.1
Hong, I.2
Kim, M.3
Lee, B.H.4
Kim, J.-H.5
Kang, K.-S.6
Kim, H.-L.7
Yoon, B.-I.8
Chung, H.9
Kong, G.10
Lee, M.-O.11
-
33
-
-
44649091222
-
Gene expression profiles of murine fatty liver induced by the administration of methotrexate
-
Lee MH, Hong I, Kim M et al (2008a) Gene expression profiles of murine fatty liver induced by the administration of methotrexate. Toxicology 249(1):75-84
-
(2008)
Toxicology
, vol.249
, Issue.1
, pp. 75-84
-
-
Lee, M.H.1
Hong, I.2
Kim, M.3
-
34
-
-
38649097885
-
Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver
-
DOI 10.1016/j.taap.2007.09.014, PII S0041008X07004218
-
Lee MH, Kim M, Lee BH et al (2008b) Subchronic effects of valproic acid on gene expression profiles for lipid metabolism in mouse liver. Toxicol Appl Pharmacol 226(3):271-284 (Pubitemid 351172413)
-
(2008)
Toxicology and Applied Pharmacology
, vol.226
, Issue.3
, pp. 271-284
-
-
Lee, M.-H.1
Kim, M.2
Lee, B.-H.3
Kim, J.-H.4
Kang, K.-S.5
Kim, H.-L.6
Yoon, B.-I.7
Chung, H.8
Kong, G.9
Lee, M.-O.10
-
35
-
-
78650509559
-
Gene expression profiling of murine hepatic steatosis induced by tamoxifen
-
Lee MH, Kim JW, Kim JH, Kang KS, Kong G, Lee MO (2010) Gene expression profiling of murine hepatic steatosis induced by tamoxifen. Toxicol Lett 199(3):416-424
-
(2010)
Toxicol Lett
, vol.199
, Issue.3
, pp. 416-424
-
-
Lee, M.H.1
Kim, J.W.2
Kim, J.H.3
Kang, K.S.4
Kong, G.5
Lee, M.O.6
-
36
-
-
0038643426
-
Inhibition of microsomal triglyceride transfer protein: Another mechanism for drug-induced steatosis in mice
-
DOI 10.1053/jhep.2003.50309
-
Letteron P, Sutton A, Mansouri A, Fromenty B, Pessayre D (2003) Inhibition of microsomal triglyceride transfer protein: another mechanism for drug-induced steatosis in mice. Hepatology 38(1):133-140 (Pubitemid 36775804)
-
(2003)
Hepatology
, vol.38
, Issue.1
, pp. 133-140
-
-
Letteron, P.1
Sutton, A.2
Mansouri, A.3
Fromenty, B.4
Pessayre, D.5
-
37
-
-
84869224848
-
Hematopoietically-expressed homeobox gene three widely-evaluated polymorphisms and risk for diabetes: A meta-analysis
-
Li X, Li Y, Song B et al (2012) Hematopoietically-expressed homeobox gene three widely-evaluated polymorphisms and risk for diabetes: a meta-analysis. PLoS ONE 7(11):e49917
-
(2012)
PLoS ONE
, vol.7
, Issue.11
-
-
Li, X.1
Li, Y.2
Song, B.3
-
38
-
-
77949329263
-
Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation
-
Liu Y, Brent GA (2010) Thyroid hormone crosstalk with nuclear receptor signaling in metabolic regulation. Trends Endocrinol Metab 21(3):166-173
-
(2010)
Trends Endocrinol Metab
, vol.21
, Issue.3
, pp. 166-173
-
-
Liu, Y.1
Brent, G.A.2
-
39
-
-
84874396118
-
Estrogen signalling and the metabolic syndrome: Targeting the hepatic estrogen receptor alpha action
-
Matic M, Bryzgalova G, Gao H et al (2013) Estrogen signalling and the metabolic syndrome: targeting the hepatic estrogen receptor alpha action. PLoS ONE 8(2):e57458
-
(2013)
PLoS ONE
, vol.8
, Issue.2
-
-
Matic, M.1
Bryzgalova, G.2
Gao, H.3
-
40
-
-
68949116060
-
A novel pregnane X receptor and S14-mediated lipogenic pathway in human hepatocyte
-
Moreau A, Teruel C, Beylot M et al (2009) A novel pregnane X receptor and S14-mediated lipogenic pathway in human hepatocyte. Hepatology 49(6):2068-2079
-
(2009)
Hepatology
, vol.49
, Issue.6
, pp. 2068-2079
-
-
Moreau, A.1
Teruel, C.2
Beylot, M.3
-
41
-
-
77949916811
-
Enhanced steatosis by nuclear receptor ligands: A study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile
-
Moya M, Gomez-Lechon MJ, Castell JV, Jover R (2010) Enhanced steatosis by nuclear receptor ligands: a study in cultured human hepatocytes and hepatoma cells with a characterized nuclear receptor expression profile. Chem Biol Interact 184(3):376-387
-
(2010)
Chem Biol Interact
, vol.184
, Issue.3
, pp. 376-387
-
-
Moya, M.1
Gomez-Lechon, M.J.2
Castell, J.V.3
Jover, R.4
-
42
-
-
84855430898
-
Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver
-
Moya M, Benet M, Guzman C et al (2012) Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver. PLoS ONE 7(1):e30014
-
(2012)
PLoS ONE
, vol.7
, Issue.1
-
-
Moya, M.1
Benet, M.2
Guzman, C.3
-
43
-
-
33747084103
-
High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening
-
DOI 10.1007/s00204-006-0091-3
-
O'Brien PJ, Irwin W, Diaz D et al (2006) High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening. Arch Toxicol 80(9):580-604 (Pubitemid 44214526)
-
(2006)
Archives of Toxicology
, vol.80
, Issue.9
, pp. 580-604
-
-
O'Brien, P.J.1
Irwin, W.2
Diaz, D.3
Howard-Cofield, E.4
Krejsa, C.M.5
Slaughter, M.R.6
Gao, B.7
Kaludercic, N.8
Angeline, A.9
Bernardi, P.10
Brain, P.11
Hougham, C.12
-
44
-
-
44149094808
-
ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: Implications in hepatic stress responses
-
DOI 10.1124/dmd.107.019380
-
Pascual M, Gomez-Lechon MJ, Castell JV, Jover R (2008) ATF5 is a highly abundant liver-enriched transcription factor that cooperates with constitutive androstane receptor in the transactivation of CYP2B6: implications in hepatic stress responses. Drug Metab Dispos 36(6):1063-1072 (Pubitemid 351717463)
-
(2008)
Drug Metabolism and Disposition
, vol.36
, Issue.6
, pp. 1063-1072
-
-
Pascual, M.1
Gomez-Lechon, M.J.2
Castell, J.V.3
Jover, R.4
-
45
-
-
0033769812
-
COUP-TF orphan nuclear receptors in development and differentiation
-
Pereira FA, Tsai MJ, Tsai SY (2000) COUP-TF orphan nuclear receptors in development and differentiation. Cell Mol Life Sci 57(10):1388-1398
-
(2000)
Cell Mol Life Sci
, vol.57
, Issue.10
, pp. 1388-1398
-
-
Pereira, F.A.1
Tsai, M.J.2
Tsai, S.Y.3
-
46
-
-
84855890664
-
Chemometric approaches to improve PLSDA model outcome for predicting human non-alcoholic fatty liver disease using UPLC-MS as a metabolic profiling tool
-
Quintás G, Portillo N, García-Cañaveras JC, Castell JV, Ferrer A, Lahoz A (2012) Chemometric approaches to improve PLSDA model outcome for predicting human non-alcoholic fatty liver disease using UPLC-MS as a metabolic profiling tool. Metabolomics 8(1):86-98
-
(2012)
Metabolomics
, vol.8
, Issue.1
, pp. 86-98
-
-
Quintás, G.1
Portillo, N.2
García-Cañaveras, J.C.3
Castell, J.V.4
Ferrer, A.5
Lahoz, A.6
-
47
-
-
70349779185
-
Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes
-
Rachek LI, Yuzefovych LV, Ledoux SP, Julie NL, Wilson GL (2009) Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes. Toxicol Appl Pharmacol 240(3):348-354
-
(2009)
Toxicol Appl Pharmacol
, vol.240
, Issue.3
, pp. 348-354
-
-
Rachek, L.I.1
Yuzefovych, L.V.2
Ledoux, S.P.3
Julie, N.L.4
Wilson, G.L.5
-
48
-
-
67649221506
-
Histological patterns in drug-induced liver disease
-
Ramachandran R, Kakar S (2009) Histological patterns in drug-induced liver disease. J Clin Pathol 62(6):481-492
-
(2009)
J Clin Pathol
, vol.62
, Issue.6
, pp. 481-492
-
-
Ramachandran, R.1
Kakar, S.2
-
49
-
-
34247136256
-
Metabolic enzymes regulated by the Myc oncogene are possible targets for chemotherapy or chemoprevention
-
DOI 10.1042/BST0350305
-
Rimpi S, Nilsson JA (2007) Metabolic enzymes regulated by the Myc oncogene are possible targets for chemotherapy or chemoprevention. Biochem Soc Trans 35(Pt 2):305-310 (Pubitemid 46596496)
-
(2007)
Biochemical Society Transactions
, vol.35
, Issue.2
, pp. 305-310
-
-
Rimpi, S.1
Nilsson, J.A.2
-
50
-
-
84876484196
-
Chemotherapy-associated liver injury in patients with colorectal liver metastases: A systematic review and meta-analysis
-
Robinson SM, Wilson CH, Burt AD, Manas DM, White SA (2012) Chemotherapy-associated liver injury in patients with colorectal liver metastases: a systematic review and meta-analysis. Ann Surg Oncol 19(13):4287-4299
-
(2012)
Ann Surg Oncol
, vol.19
, Issue.13
, pp. 4287-4299
-
-
Robinson, S.M.1
Wilson, C.H.2
Burt, A.D.3
Manas, D.M.4
White, S.A.5
-
52
-
-
0036200587
-
Liver-enriched transcription factors in liver function and development. Part I: The hepatocyte nuclear factor network and liver-specific gene expression
-
DOI 10.1124/pr.54.1.129
-
Schrem H, Klempnauer J, Borlak J (2002) Liver-enriched transcription factors in liver function and development. Part I: the hepatocyte nuclear factor network and liver-specific gene expression. Pharmacol Rev 54(1):129-158 (Pubitemid 34208830)
-
(2002)
Pharmacological Reviews
, vol.54
, Issue.1
, pp. 129-158
-
-
Schrem, H.1
Klempnauer, J.2
Borlak, J.3
-
53
-
-
2642549921
-
Liver-enriched transcription factors in liver function and development. Part II: The C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation
-
DOI 10.1124/pr.56.2.5
-
Schrem H, Klempnauer J, Borlak J (2004) Liver-enriched transcription factors in liver function and development. Part II: the C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation. Pharmacol Rev 56(2):291-330 (Pubitemid 38720832)
-
(2004)
Pharmacological Reviews
, vol.56
, Issue.2
, pp. 291-330
-
-
Schrem, H.1
Klempnauer, J.2
Borlak, J.3
-
54
-
-
84860177830
-
Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs
-
Tolosa L, Pinto S, Donato MT et al (2012) Development of a multiparametric cell-based protocol to screen and classify the hepatotoxicity potential of drugs. Toxicol Sci 127(1):187-198
-
(2012)
Toxicol Sci
, vol.127
, Issue.1
, pp. 187-198
-
-
Tolosa, L.1
Pinto, S.2
Donato, M.T.3
-
55
-
-
36549009674
-
Gene expression profiling in livers of mice after acute inhibition of beta-oxidation
-
DOI 10.1016/j.ygeno.2007.08.004, PII S0888754307002042
-
van der Leij FR, Bloks VW, Grefhorst A et al (2007) Gene expression profiling in livers of mice after acute inhibition of beta-oxidation. Genomics 90(6):680-689 (Pubitemid 350176644)
-
(2007)
Genomics
, vol.90
, Issue.6
, pp. 680-689
-
-
Van Der Leij, F.R.1
Bloks, V.W.2
Grefhorst, A.3
Hoekstra, J.4
Gerding, A.5
Kooi, K.6
Gerbens, F.7
Te, M.G.8
Kuipers, F.9
-
56
-
-
63349084334
-
Hematopoietically expressed homeobox is a target gene of farnesoid x receptor in chenodeoxycholic acid-induced liver hypertrophy
-
Xing X, Burgermeister E, Geisler F et al (2009) Hematopoietically expressed homeobox is a target gene of farnesoid x receptor in chenodeoxycholic acid-induced liver hypertrophy. Hepatology 49(3):979-988
-
(2009)
Hepatology
, vol.49
, Issue.3
, pp. 979-988
-
-
Xing, X.1
Burgermeister, E.2
Geisler, F.3
-
57
-
-
33749624887
-
Hepatic gene expression profiling and lipid homeostasis in mice exposed to seatogenic drug, tetracycline
-
DOI 10.1093/toxsci/kfl078
-
Yin HQ, Kim M, Kim JH et al (2006) Hepatic gene expression profiling and lipid homeostasis in mice exposed to steatogenic drug, tetracycline. Toxicol Sci 94(1):206-216 (Pubitemid 44542343)
-
(2006)
Toxicological Sciences
, vol.94
, Issue.1
, pp. 206-216
-
-
Yin, H.-Q.1
Kim, M.2
Kim, J.-H.3
Kong, G.4
Lee, M.-O.5
Kang, K.-S.6
Yoon, B.-I.7
Kim, H.-L.8
Lee, B.-H.9
-
58
-
-
15044362819
-
GATA6 is essential for embryonic development of the liver but dispensable for early heart formation
-
DOI 10.1128/MCB.25.7.2622-2631.2005
-
Zhao R, Watt AJ, Li J, Luebke-Wheeler J, Morrisey E, Duncan SA (2005) GATA6 is essential for embryonic development of the liver but dispensable for early heart formation. Mol Cell Biol 25(7):2622-2631 (Pubitemid 40381626)
-
(2005)
Molecular and Cellular Biology
, vol.25
, Issue.7
, pp. 2622-2631
-
-
Zhao, R.1
Watt, A.J.2
Li, J.3
Luebke-Wheeler, J.4
Morrisey, E.E.5
Duncan, S.A.6
-
59
-
-
38649096259
-
Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis
-
Zhou J, Febbraio M, Wada T et al (2008) Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology 134(2):556-567
-
(2008)
Gastroenterology
, vol.134
, Issue.2
, pp. 556-567
-
-
Zhou, J.1
Febbraio, M.2
Wada, T.3
-
60
-
-
33947267189
-
Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases
-
DOI 10.1002/bjs.5719
-
Zorzi D, Laurent A, Pawlik TM, Lauwers GY, Vauthey JN, Abdalla EK (2007) Chemotherapy-associated hepatotoxicity and surgery for colorectal liver metastases. Br J Surg 94(3):274-286 (Pubitemid 46423843)
-
(2007)
British Journal of Surgery
, vol.94
, Issue.3
, pp. 274-286
-
-
Zorzi, D.1
Laurent, A.2
Pawlik, T.M.3
Lauwers, G.Y.4
Vauthey, J.-N.5
Abdalla, E.K.6
-
61
-
-
79955042823
-
Vitamin D and the vitamin D receptor in liver pathophysiology
-
Zuniga S, Firrincieli D, Housset C, Chignard N (2011) Vitamin D and the vitamin D receptor in liver pathophysiology. Clin Res Hepatol Gastroenterol 35(4):295-302
-
(2011)
Clin Res Hepatol Gastroenterol
, vol.35
, Issue.4
, pp. 295-302
-
-
Zuniga, S.1
Firrincieli, D.2
Housset, C.3
Chignard, N.4
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